Heart Failure | Exercise Training and Testosterone Replacement in Heart Failure Patients
Heart Failure research study
What is the primary objective of this study?
The purpose of this study is to determine if exercise training with or without testosterone
replacement can improve cardiopathy in heart failure patients
Who is eligible to participate?
- heart failure
- left ventricular fraction ejection < 45%
- chronic renal failure
- normal testosterone
- pace maker
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Drug:Testosterone replacementApplication quarterly of Testosterone Undecylate
Other:Exercise trainingAerobic and strength exercise training
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Exercise trainingAerobic and strength exercise training
Testosterone replacementTestosterone replacement will be done quarterly
Testosterone replacement+ExerciseBoth Testosterone replacement and Exercise will done
Start Date: July 2009
Completed Date: July 2015
Phase: Phase 4
Primary Outcome: Microneurography
Secondary Outcome: Cardiopulmonary exercise
Study sponsors, principal investigator, and references
Principal Investigator: Maria Janieire N Alves, MD; PhD
Lead Sponsor: University of Sao Paulo General Hospital