Multiple Sclerosis | Upper Limbs Intervention in Multiple Sclerosis
Multiple Sclerosis research study
What is the primary objective of this study?
Multiple sclerosis is a chronic and highly disabling disorder with considerable social impact and economic consequences. It is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. Different areas are affected, including manual dexterity, strength, coordination and function. The objective of this study is to evaluate the improvement in these variables in patients with multiple sclerosis after a 8-weeks intervention focused on upper limbs.
Who is eligible to participate?
Inclusion Criteria: - Patients diagnosed with multiple sclerosis. - Subjects who can complete the assessment battery of tests at the beginning and at the end of the study Exclusion Criteria: - Auditive and visual disturbances. - Cognitive problems. - Psychiatric pathology. - Sensorial disturbances. - Traumatic pathology of the hand. - Concomitant neurological conditions
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Other:Upper limbs interventionAn 8-week intervention with different exercises will be performed. This intervention will focus on upper limbs. The exercises will include plaster of resistance, elastic bands and other exercises.
Other:Usual treatmentOccupational therapy and physiotherapy, twice a week, as usual.
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Experimental groupThe patients included in this group will receive an intensive intervention based on upper limbs intervention with exercises added to the usual treatment they receive.
Control groupPatients with multiple sclerosis not included in the intensive intervention. They receive the usual treatment of occupational and physical therapy.
Start Date: January 2014
Completed Date: February 2016
Primary Outcome: Changes in manual dexterity
Secondary Outcome: Changes in apraxia
Study sponsors, principal investigator, and references
Principal Investigator: Marie Carmen Valenza, PhD
Lead Sponsor: Universidad de Granada
Ortiz-Rubio A, Cabrera-Martos I, Rodríguez-Torres J, Fajardo-Contreras W, Díaz-Pelegrina A, Valenza MC. Effects of a Home-Based Upper Limb Training Program in Patients With Multiple Sclerosis: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2016 Dec;97(12):2027-2033. doi: 10.1016/j.apmr.2016.05.018. Epub 2016 Jun 22.