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Multiple Sclerosis | Upper Limbs Intervention in Multiple Sclerosis

Multiple Sclerosis research study

What is the primary objective of this study?

Multiple sclerosis is a chronic and highly disabling disorder with considerable social impact and economic consequences. It is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. Different areas are affected, including manual dexterity, strength, coordination and function. The objective of this study is to evaluate the improvement in these variables in patients with multiple sclerosis after a 8-weeks intervention focused on upper limbs.

Who is eligible to participate?

Inclusion Criteria: - Patients diagnosed with multiple sclerosis. - Subjects who can complete the assessment battery of tests at the beginning and at the end of the study Exclusion Criteria: - Auditive and visual disturbances. - Cognitive problems. - Psychiatric pathology. - Sensorial disturbances. - Traumatic pathology of the hand. - Concomitant neurological conditions

Which medical condition, disease, disorder, syndrome, illness, or injury is researched?

Multiple Sclerosis

Study Interventions

Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.

Other:Upper limbs interventionAn 8-week intervention with different exercises will be performed. This intervention will focus on upper limbs. The exercises will include plaster of resistance, elastic bands and other exercises.

Other:Usual treatmentOccupational therapy and physiotherapy, twice a week, as usual.

Study Arms

Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.

Experimental groupThe patients included in this group will receive an intensive intervention based on upper limbs intervention with exercises added to the usual treatment they receive.

Control groupPatients with multiple sclerosis not included in the intensive intervention. They receive the usual treatment of occupational and physical therapy.

Study Status

Completed

Start Date: January 2014

Completed Date: February 2016

Phase: N/A

Type: Interventional

Design:

Primary Outcome: Changes in manual dexterity

Secondary Outcome: Changes in apraxia

Study sponsors, principal investigator, and references

Principal Investigator: Marie Carmen Valenza, PhD

Lead Sponsor: Universidad de Granada

Collaborator:

More information:https://clinicaltrials.gov/show/NCT02047825

Ortiz-Rubio A, Cabrera-Martos I, Rodríguez-Torres J, Fajardo-Contreras W, Díaz-Pelegrina A, Valenza MC. Effects of a Home-Based Upper Limb Training Program in Patients With Multiple Sclerosis: A Randomized Controlled Trial. Arch Phys Med Rehabil. 2016 Dec;97(12):2027-2033. doi: 10.1016/j.apmr.2016.05.018. Epub 2016 Jun 22.

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