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What symptoms can Sulfasalazine cause?

Sulfasalazine Safety Information and Side Effects

Sulfasalazine Safety Information

Pyrexia ( 106 reports)    ➢ More

Cerebral Infarction, Hemiparesis, Hypersensitivity, Headache, Pyrexia

This case suggests a potential Sulfasalazine Pyrexia side effect(s) that can have serious consequences. A 13-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): crohn^s disease and used Sulfasalazine (dosage: 1.5 G, Daily) starting NS. Soon after starting Sulfasalazine the patient began experiencing various side effects, including:
  • Cerebral Infarction
  • Hemiparesis
  • Hypersensitivity
  • Headache
  • Pyrexia
Drugs used concurrently:NA. Although Sulfasalazine demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pyrexia, may still occur.

Rash ( 62 reports)    ➢ More

Rash, Liver Function Test Abnormal, Neutropenic Sepsis, Hepatitis

Adverse event was reported on Mar 12, 2014 by a male taking Sulfasalazine (Dosage: NA) . Location: GB , 40 years of age, Directly after treatment started, patient experienced the unwanted or unexpected Sulfasalazine side effects: rash, liver function test abnormal, neutropenic sepsis, hepatitis.
Associated medications used:
  • 6-mercaptopurine (Unk)
  • Pentasa (Unk)
  • Co-codamol (Unk)
  • Difflam (Unk (spray))
  • Penicillin V (Unk)
The patient was hospitalized.

Headache ( 60 reports)    ➢ More

Cerebral Infarction, Hemiparesis, Hypersensitivity, Headache, Pyrexia

This Headache problem was reported by a physician from US. A 13-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): crohn^s disease.On NS a consumer started treatment with Sulfasalazine (dosage: 1.5 G, Daily). The following health products were being taken at the same time: NA. When commencing Sulfasalazine, the patient experienced the following unwanted symptoms /side effects:
  • Cerebral Infarction
  • Hemiparesis
  • Hypersensitivity
  • Headache
  • Pyrexia
Although all health products are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Headache, may become evident only after a product is in use by the general population.

Nausea ( 51 reports)    ➢ More

Abdominal Pain, Nausea

A case of a 52-year-old female patient (weight: NA) from US was presented. The patient developed the following symptoms/conditions: rheumatoid arthritis and was treated with Sulfasalazine (dosage: NA) starting Feb 18, 2008. Concurrently used drugs: NA. Soon after that, the subject experienced the following of symptoms:
  • Abdominal Pain
  • Nausea
This opens a possibility that Sulfasalazine could cause Nausea and that some female subjects may be more susceptible.

Lymphadenopathy ( 41 reports)    ➢ More

Toxic Epidermal Necrolysis, Stomatitis, Lymphadenopathy, Abdominal Pain, Fatigue, Headache, Nausea, Oedema, Pharyngitis

on Dec 13, 2012 a Female from CA , 42 years of age, weighting 163.1 lb, was treated with Sulfasalazine. Directly after treatment started, patient experienced the unwanted or unexpected Sulfasalazine side effects: toxic epidermal necrolysis, stomatitis, lymphadenopathy, abdominal pain, fatigue, headache, nausea, oedema, pharyngitis. Sulfasalazine dosage: Unk, 3x/day.
Associated medications used:
  • Amitriptyline (Unk)
  • Calcitriol (Unk)
  • Cefazolin (Unk)
  • Clonazepam (Unk)
  • Hydrochlorothiazide (25mg Daily)
  • L-thyroxin (0.15 Mg, Unk)
The patient was hospitalized.

Common Sulfasalazine Side Effects

Click to view detailed reports:

Pyrexia (106)
Rash (62)
Headache (60)
Nausea (51)
Lymphadenopathy (41)
Neutropenia (40)
Diarrhoea (40)
Dyspnoea (37)
Fatigue (37)
Malaise (33)
Cough (30)
Arthralgia (29)
Hypersensitivity (29)
Agranulocytosis (27)
Interstitial Lung Disease (27)
Vomiting (25)
Pruritus (24)
Anaemia (24)
Alanine Aminotransferase Increased (24)
Cytolytic Hepatitis (23)
Eosinophilia (23)
Hepatitis (23)
Liver Disorder (22)
Pneumonia (22)
Asthenia (21)
Erythema (21)
Liver Function Test Abnormal (21)
Pain (20)
Colitis Ulcerative (20)
Toxic Epidermal Necrolysis (18)
Pancytopenia (18)
Hepatic Function Abnormal (18)
Chills (18)
C-reactive Protein Increased (18)
Abdominal Pain (18)
Lung Disorder (17)
Depression (17)
Oropharyngeal Pain (17)
Sepsis (17)
Face Oedema (16)
Stevens-johnson Syndrome (16)
Renal Failure (15)
Rash Maculo-papular (15)
Pulmonary Fibrosis (15)
Neutropenic Sepsis (15)
Dizziness (15)
Aspartate Aminotransferase Increased (14)
Swelling Face (14)
Histiocytosis Haematophagic (13)
Leukopenia (13)

➢ More

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Sulfasalazine Forum

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