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ACUTE GRAFT VERSUS HOST DISEASE IN SKIN side effect

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Cyclosporine Side Effects Report #5677016-0
Health Professional from PAKISTAN reported CYCLOSPORINE problem on Mar 12, 2008. Male patient, 22 years of age, was diagnosed with prophylaxis against graft versus host disease, stem cell transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, aspergillosis, cough, crepitations, dyspnoea, febrile neutropenia, nephropathy toxic, nodule, pneumonia cytomegaloviral, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with METHOTREXATE, BUSULFAN, CYCLOPHOSPHAMIDE, ANTIBIOTICS. Patient was hospitalized. Patient died.

Cyclosporine Side Effects Report #5682243-2
CYCLOSPORINE problem was reported by a Consumer or non-health professional from ITALY on Mar 13, 2008. Female patient, child 9 years of age, was diagnosed with graft versus host disease, aplastic anaemia and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, ataxia, convulsion, diplopia, guillain-barre syndrome, miller fisher syndrome, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with ANTITHYMOCYTE GLOBULIN, CYCLOPHOSPHAMIDE, METHOTREXATE. Patient recovered.

Revlimid Side Effects Report #5637757-8
Physician from UNITED STATES reported REVLIMID problem on Feb 11, 2008. Female patient, 62 years of age, was diagnosed with multiple myeloma and was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, acute myeloid leukaemia, alpha haemolytic streptococcal infection, blood culture positive, bone marrow transplant rejection, febrile neutropenia, hepatotoxicity, thrombocytopenia, . REVLIMID dosage: 5 MG, 1 IN 1 D, ORAL; 10 MG, 1 IN 1 D, ORAL. Patient died on 12/02/2007.

Cytarabine Side Effects Report #5597224-7
CYTARABINE problem was reported by a Health Professional from JAPAN on Jan 14, 2008. Male patient, 17 years of age, was diagnosed with stem cell transplant and was treated with CYTARABINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, blood beta-d-glucan increased, chest pain, chronic graft versus host disease, dyspnoea, dyspnoea exertional, hepatic function abnormal, hypogammaglobulinaemia, lymphopenia, . CYTARABINE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, IRRADIATION, METHOTREXATE, TOSUFLOXACIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, FLUCONAZOLE, CYCLOSPORINE. Patient was hospitalized. Patient recovered.


Methotrexate Side Effects Report #5598688-5
Physician from GERMANY reported METHOTREXATE problem on Jan 08, 2008. Female patient, child 5 years of age, was diagnosed with prophylaxis against graft versus host disease, bone marrow conditioning regimen and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, bacteria stool identified, enterococcal infection, mucosal inflammation, pyrexia, . METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, CYCLOSPORINE. Patient recovered.

Methotrexate Side Effects Report #5598690-3
METHOTREXATE problem was reported by a Physician from GERMANY on Jan 08, 2008. Female patient, child 10 years of age, was diagnosed with prophylaxis against graft versus host disease, bone marrow conditioning regimen and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, epstein-barr virus infection, leukaemia recurrent, mucosal inflammation, pericardial effusion, pulmonary oedema, renal failure, . METHOTREXATE dosage: unknown. During the same period patient was treated with ETOPOSIDE, CYCLOSPORINE. Patient recovered.

Zonisamide Side Effects Report #5613454-X
Health Professional from JAPAN reported ZONISAMIDE problem on Jan 10, 2008. Female patient was diagnosed with convulsion and was treated with ZONISAMIDE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, alopecia, autoimmune disorder, human herpes virus 6 serology positive, pancytopenia, raynaud's phenomenon, scleroderma, thyroid disorder, . ZONISAMIDE dosage: 200 MG DAILY, ORAL. During the same period patient was treated with CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5613959-1
PROGRAF problem was reported by a Physician from JAPAN on Jan 10, 2008. Female patient, child 10 years of age, was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, chest pain, disease progression, pleural effusion, pleurisy, . PROGRAF dosage: 0.03 MG/KG, IV NOS. During the same period patient was treated with PREDNISOLONE. Patient recovered.

Cytarabine Side Effects Report #5535264-4
Physician from UNITED STATES reported CYTARABINE problem on Nov 16, 2007. Female patient, 33 years of age, was diagnosed with graft versus host disease, acute graft versus host disease and was treated with CYTARABINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, lip and/or oral cavity cancer, . CYTARABINE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ANTINEOPLASTICS, METHOTREXATE, AZATHIOPRINE, PREDNISONE. Patient died.


Prograf Side Effects Report #5542788-2
PROGRAF problem was reported by a Physician from UNITED STATES on Nov 27, 2007. Male patient, 49 years of age, was diagnosed with stem cell transplant and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, hepatic enzyme increased, . PROGRAF dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5542811-5
Physician from UNITED STATES reported PROGRAF problem on Nov 27, 2007. Male patient, 57 years of age, was diagnosed with stem cell transplant and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, . PROGRAF dosage: unknown. During the same period patient was treated with PREDNISONE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5542812-7
PROGRAF problem was reported by a Physician from UNITED STATES on Nov 27, 2007. Female patient, 55 years of age, was diagnosed with stem cell transplant and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, . PROGRAF dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5542822-X
Physician from UNITED STATES reported PROGRAF problem on Nov 27, 2007. Male patient, 36 years of age, was diagnosed with stem cell transplant and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, . PROGRAF dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, MYCOPHENOLATE MOFETIL. Patient recovered.

Prograf Side Effects Report #5542911-X
PROGRAF problem was reported by a Physician from UNITED STATES on Nov 27, 2007. Female patient, 33 years of age, was diagnosed with bone marrow transplant and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, . PROGRAF dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE, HYDROXYCHLOROQUINE SULPHATE. Patient recovered.


Prograf Side Effects Report #5542932-7
Physician from UNITED STATES reported PROGRAF problem on Nov 27, 2007. Female patient, 54 years of age, was diagnosed with bone marrow transplant and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, graft versus host disease in lung, . PROGRAF dosage: unknown. During the same period patient was treated with PREDNISOLONE ACETATE. Patient recovered.

Irradiation Side Effects Report #5512164-7
IRRADIATION problem was reported by a Consumer or non-health professional from JAPAN on Oct 31, 2007. Female patient, 28 years of age, was treated with IRRADIATION. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, cytomegalovirus antigen positive, febrile neutropenia, . IRRADIATION dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHOTREXATE, ENDOXAN, NEUPOGEN. Patient recovered.

Cyclosporine Side Effects Report #5524705-4
Health Professional from TURKEY reported CYCLOSPORINE problem on Nov 14, 2007. Female patient, child 7 years of age, was diagnosed with bone marrow transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, blood sodium decreased, cerebral atrophy, electrolyte imbalance, encephalopathy, epistaxis, febrile neutropenia, fluid overload, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with METHOTREXATE, BUSULFAN, CYCLOPHOSPHAMIDE, ATGAM. Patient was hospitalized. Patient died.

Irradiation Side Effects Report #5524774-1
IRRADIATION problem was reported by a Consumer or non-health professional from JAPAN on Nov 14, 2007. Female patient, 28 years of age, was treated with IRRADIATION. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, cytomegalovirus antigen positive, febrile neutropenia, . IRRADIATION dosage: unknown. During the same period patient was treated with CYCLOSPORINE, METHOTREXATE, CYCLOPHOSPHAMIDE, NEUPOGEN. Patient recovered.

Cyclosporine Side Effects Report #5526092-4
Consumer or non-health professional from GERMANY reported CYCLOSPORINE problem on Nov 05, 2007. Female patient, 56 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, acute respiratory distress syndrome, blood lactate dehydrogenase increased, coma, convulsion, eyelid ptosis, hypertension, leukoencephalopathy, mucosal inflammation, . CYCLOSPORINE dosage: 5 MG/KG/DAY, DAILY DOSES WERE REDUCED. During the same period patient was treated with METHOTREXATE, FLUDARABINE, CARMUSTINE, MELPHALAN, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient died.


Cytarabine Side Effects Report #5527446-2
CYTARABINE problem was reported by a Health Professional from UNITED STATES on Nov 13, 2007. Female patient, 33 years of age, was diagnosed with chronic myeloid leukaemia, prophylaxis against graft versus host disease, stem cell transplant and was treated with CYTARABINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, lip and/or oral cavity cancer, . CYTARABINE dosage: unknown. During the same period patient was treated with METHOTREXATE, AZATHIOPRINE, PREDNISONE, CYCLOPHOSPHAMIDE, IRRADIATION. Patient recovered.

Cytarabine Side Effects Report #5533453-6
Consumer or non-health professional from UNITED STATES reported CYTARABINE problem on Nov 14, 2007. Female patient, 33 years of age, was diagnosed with acute myeloid leukaemia, prophylaxis against graft versus host disease and was treated with CYTARABINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, lip and/or oral cavity cancer, refusal of treatment by patient, . CYTARABINE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, AZATHIOPRINE, PREDNISONE. Patient died.

Primaxin Side Effects Report #5478768-5
PRIMAXIN problem was reported by a Health Professional from MALAYSIA on Sept 25, 2007. Female patient, 42 years of age, was diagnosed with sepsis, transplant, fungal infection and was treated with PRIMAXIN. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, pathogen resistance, rash macular, sepsis, . PRIMAXIN dosage: unknown. During the same period patient was treated with VANCOMYCIN, METHYLPREDNISOLONE, CYCLOSPORINE, TACROLIMUS, GLOBULIN, INFLIXIMAB, FLUCONAZOLE, ACYCLOVIR. Patient died.

Fludarabine Side Effects Report #5479816-9
Consumer or non-health professional from JAPAN reported FLUDARABINE PHOSPHATE problem on Sept 27, 2007. Male patient, child 12 years of age, was diagnosed with stem cell transplant and was treated with FLUDARABINE PHOSPHATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, rash, stomatitis, . FLUDARABINE PHOSPHATE dosage: 25 MG/M2. During the same period patient was treated with MELPHALAN, METHOTREXATE, SANDIMMUNE. Patient recovered.

Primaxin Side Effects Report #5483132-9
PRIMAXIN problem was reported by a Health Professional from MALAYSIA on Sept 25, 2007. Female patient, 42 years of age, was diagnosed with sepsis, transplant, fungal infection and was treated with PRIMAXIN. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, pathogen resistance, rash macular, sepsis, . PRIMAXIN dosage: unknown. During the same period patient was treated with VANCOMYCIN, METHYLPREDNISOLONE, CYCLOSPORINE, TACROLIMUS, GLOBULIN, INFLIXIMAB, FLUCONAZOLE, ACYCLOVIR. Patient died.

Prograf Side Effects Report #5492842-9
Physician from AUSTRALIA reported PROGRAF problem on Oct 05, 2007. Male patient, 39 years of age, was diagnosed with stem cell transplant and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, blood lactate dehydrogenase decreased, blood lactate dehydrogenase increased, colonic polyp, diarrhoea, disease progression, hepatic function abnormal, hepatosplenomegaly, . PROGRAF dosage: unknown. During the same period patient was treated with CYCLOSPORINE, PREDNISOLONE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, ETANERCEPT. Patient died.

Prograf Side Effects Report #5449541-9
PROGRAF problem was reported by a Physician from UNITED STATES on Aug 09, 2007. Male patient, 63 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, disease recurrence, diverticulitis, escherichia bacteraemia, hepatic infection fungal, mucormycosis, neutropenia, pancytopenia, pneumonitis, . PROGRAF dosage: unknown. During the same period patient was treated with CELLCEPT, METHOTREXATE, FLUCONAZOLE, FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE. Patient was hospitalized. Patient died.

Abelcet Side Effects Report #5453477-7
Physician from UNITED STATES reported ABELCET problem on Sept 06, 2007. Male patient, 63 years of age, was diagnosed with zygomycosis and was treated with ABELCET. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, diarrhoea, disease recurrence, hepatic lesion, large intestinal ulcer, mucormycosis, pleuritic pain, pneumonitis, . ABELCET dosage: 5 MG/KG; QD; IV. During the same period patient was treated with FLUCONAZOLE, MYCOPHENOLATE MOFETIL, TACROLIMUS. Patient died.

Prednisolone Side Effects Report #5467659-1
PREDNISOLONE problem was reported by a Consumer or non-health professional from JAPAN on Sept 10, 2007. Male patient, 14 years of age, was diagnosed with acute lymphocytic leukaemia, prophylaxis against graft versus host disease and was treated with PREDNISOLONE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, blood cholesterol increased, blood triglycerides increased, chronic graft versus host disease, cryptogenic organising pneumonia, diabetes mellitus, diabetic ketoacidosis, mucosal inflammation, post procedural complication, . PREDNISOLONE dosage: unknown. During the same period patient was treated with TACROLIMUS, VINCRISTINE, DANORUBICIN, CYCLOPHOSPHAMIDE, CYTARABINE, ETOPOSIDE, METHOTREXATE. Patient was hospitalized. Patient recovered.

Cyclosporine Side Effects Report #5404823-1
Health Professional from SWEDEN reported CYCLOSPORINE problem on July 31, 2007. Male patient, child 9 years of age, was diagnosed with stem cell transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, blood lactate dehydrogenase increased, c-reactive protein increased, dehydration, enterococcal sepsis, haemodialysis, haemolysis, haemolytic uraemic syndrome, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with SULFAMETHOXAZOLE W, ONDANSETRON, ALLOPURINOL, ACETAMINOPHEN, CODEINE SUL, MESNA, ACYCLOVIR, FLUCONAZOLE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5379245-2
METHOTREXATE problem was reported by a Consumer or non-health professional from on June 27, 2007. Female patient, child 9 years of age, was diagnosed with prophylaxis against graft versus host disease, bone marrow conditioning regimen, immunosuppression and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, coordination abnormal, diplopia, grand mal convulsion, haemolytic anaemia, miller fisher syndrome, . METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, CYCLOSPORINE. Patient recovered.

Fludara Side Effects Report #5381115-0
Consumer or non-health professional from ITALY reported FLUDARA problem on June 27, 2007. Female patient, child 9 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with FLUDARA. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, convulsion, haemolytic anaemia, miller fisher syndrome, . FLUDARA dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE. Patient recovered.

Cyclosporine Side Effects Report #5382591-X
CYCLOSPORINE problem was reported by a Health Professional from SWEDEN on June 28, 2007. Male patient, child 9 years of age, was diagnosed with stem cell transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, blood lactate dehydrogenase increased, c-reactive protein increased, dehydration, enterococcal sepsis, haemodialysis, haemolysis, haemolytic uraemic syndrome, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with SULFAMETHOXAZOLE W, ONDANSETRON, ALLOPURINOL, ACETAMINOPHEN, CODEINE SUL, MESNA, ACYCLOVIR, FLUCONAZOLE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5387643-6
Physician from CHINA reported PROGRAF problem on July 02, 2007. Male patient, 64 years of age, was diagnosed with liver transplant, graft versus host disease and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, bone marrow failure, cerebral haemorrhage, disease progression, pancytopenia, . PROGRAF dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, ZENAPAX. Patient died.

Thymoglobulin Side Effects Report #5423722-2
THYMOGLOBULIN problem was reported by a Physician from UNITED STATES on Jan 19, 2006. Male patient, 56 years of age, weighting 191.0 lb, was diagnosed with multiple myeloma and was treated with THYMOGLOBULIN. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, epstein-barr virus test positive, gastroenteritis cryptosporidial, lymphoma, lymphoproliferative disorder, post procedural complication, retroperitoneal lymphadenopathy, . THYMOGLOBULIN dosage: 0.5 MG/KG IV. During the same period patient was treated with CORTICOSTEROIDS, CYCYLOSPORINE, MEDROL, VORICONAZOLE, VALCYTE, ACTICAL, NITAZOXANIDE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5379245-2
Consumer or non-health professional from reported METHOTREXATE problem on June 27, 2007. Female patient, child 9 years of age, was diagnosed with prophylaxis against graft versus host disease, bone marrow conditioning regimen, immunosuppression and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, coordination abnormal, diplopia, grand mal convulsion, haemolytic anaemia, miller fisher syndrome, . METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, FLUDARABINE PHOSPHATE, CYCLOSPORINE. Patient recovered.

Fludara Side Effects Report #5381115-0
FLUDARA problem was reported by a Consumer or non-health professional from ITALY on June 27, 2007. Female patient, child 9 years of age, was diagnosed with bone marrow conditioning regimen, prophylaxis against graft versus host disease and was treated with FLUDARA. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, convulsion, haemolytic anaemia, miller fisher syndrome, . FLUDARA dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, ANTITHYMOCYTE IMMUNOGLOBULIN, CYCLOSPORINE. Patient recovered.

Cyclosporine Side Effects Report #5382591-X
Health Professional from SWEDEN reported CYCLOSPORINE problem on June 28, 2007. Male patient, child 9 years of age, was diagnosed with stem cell transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, blood lactate dehydrogenase increased, c-reactive protein increased, dehydration, enterococcal sepsis, haemodialysis, haemolysis, haemolytic uraemic syndrome, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with SULFAMETHOXAZOLE W, ONDANSETRON, ALLOPURINOL, ACETAMINOPHEN, CODEINE SUL, MESNA, ACYCLOVIR, FLUCONAZOLE. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5387643-6
PROGRAF problem was reported by a Physician from CHINA on July 02, 2007. Male patient, 64 years of age, was diagnosed with liver transplant, graft versus host disease and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, bone marrow failure, cerebral haemorrhage, disease progression, pancytopenia, . PROGRAF dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, ZENAPAX. Patient died.

Thymoglobulin Side Effects Report #5423722-2
Physician from UNITED STATES reported THYMOGLOBULIN problem on Jan 19, 2006. Male patient, 56 years of age, weighting 191.0 lb, was diagnosed with multiple myeloma and was treated with THYMOGLOBULIN. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, epstein-barr virus test positive, gastroenteritis cryptosporidial, lymphoma, lymphoproliferative disorder, post procedural complication, retroperitoneal lymphadenopathy, . THYMOGLOBULIN dosage: 0.5 MG/KG IV. During the same period patient was treated with CORTICOSTEROIDS, CYCYLOSPORINE, MEDROL, VORICONAZOLE, VALCYTE, ACTICAL, NITAZOXANIDE. Patient was hospitalized. Patient recovered.

Cyclosporine Side Effects Report #5764670-8
CYCLOSPORINE problem was reported by a Health Professional from UNITED STATES on May 27, 2008. Female patient, 23 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, convulsion, cystitis haemorrhagic, metabolic disorder, metabolic encephalopathy, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with BUSULFAN, CYCLOPHOSPHAMIDE, MESNA, PLATELETS. Patient recovered.

Busulfex Side Effects Report #5767265-5
Consumer or non-health professional from GERMANY reported BUSULFEX problem on May 28, 2008. Male patient, 67 years of age, was diagnosed with stem cell transplant and was treated with BUSULFEX. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, cytomegalovirus infection, deafness, demyelination, disorientation, hemianopia homonymous, incontinence, . BUSULFEX dosage: 4 ML, DAILY DOSE INTRAVENOUS. During the same period patient was treated with CYCLOSPORINE, FLUDARABINE PHOSPHATE, ALEMTUZUMAS, PREDNISOLONE. Patient died.

Clolar Side Effects Report #5776285-6
CLOLAR problem was reported by a Health Professional from UNITED STATES on June 06, 2008. Female patient, 60 years of age, weighting 193.1 lb, was diagnosed with acute myeloid leukaemia and was treated with CLOLAR. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, acute myeloid leukaemia recurrent, deep vein thrombosis, haemosiderosis, hepatocellular injury, hyperglycaemia, hypermagnesaemia, liver injury, no therapeutic response, . CLOLAR dosage: 53 MG, QDX5, INTRAVENOUS. During the same period patient was treated with BUSULFAN. Patient was hospitalized. Patient recovered.

Prednisolone Side Effects Report #5736835-2
Consumer or non-health professional from GERMANY reported PREDNISOLONE problem on Apr 22, 2008. Male patient was diagnosed with acute graft versus host disease in skin and was treated with PREDNISOLONE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, cytomegalovirus infection, deafness, demyelination, disease recurrence, hemianopia homonymous, incontinence, jc virus infection, . PREDNISOLONE dosage: 50 MG /D. During the same period patient was treated with FLUDARABINE PHOSPHATE, CYCLOPHOSPHAMIDE, ALEMTUZUMAB, BUSULFAN. Patient died.

Fludarabine Side Effects Report #5738634-4
FLUDARABINE PHOSPHATE problem was reported by a Health Professional from GERMANY on May 06, 2008. Male patient was diagnosed with b-cell small lymphocytic lymphoma and was treated with FLUDARABINE PHOSPHATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, progressive multifocal leukoencephalopathy, . FLUDARABINE PHOSPHATE dosage: AS USED: 25 MG/M2. During the same period patient was treated with FLUDARABINE PHOSPHATE, ALEMTUZUMAB, PREDNISONE, CYCLOPHOSPHAMIDE, VINCRISTINE. Patient was hospitalized. Patient died.

Velcade Side Effects Report #5738751-9
Health Professional from UNITED STATES reported VELCADE problem on May 01, 2008. Male patient, 60 years of age, was diagnosed with myelofibrosis and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, glucose tolerance impaired, toxic epidermal necrolysis, . VELCADE dosage: 1.3 MG/M2, INTRAVENOUS. During the same period patient was treated with TACROLIMUS, METHOTREXATE, ACTOS, ACYCLOVIR, BACTRIM, CELLCEPT, CLOBETASOL PROPIONATE, DIOVAN HCT. Patient was hospitalized. Patient recovered.

Antithymocyte Side Effects Report #5693239-9
ANTITHYMOCYTE IMMUNOGLOBULIN problem was reported by a Consumer or non-health professional from JAPAN on Mar 27, 2008. Female patient, child 4 years of age, was diagnosed with graft versus host disease and was treated with ANTITHYMOCYTE IMMUNOGLOBULIN. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, bacterial culture positive, biopsy skin abnormal, lymph node pain, lymphadenopathy, mycobacterium chelonei infection, purulent discharge, rash, . ANTITHYMOCYTE IMMUNOGLOBULIN dosage: 10 MG/KG/DAY. During the same period patient was treated with CYCLOSPORINE, METHYLPREDNISOLONE, MYCOPHENOLATE MOFETIL, BUSULFAN, CYCLOPHOSPHAMIDE, ETOPOSIDE, METHOTREXATE. Patient recovered.

Tacrolimus Side Effects Report #5697471-X
Health Professional from GERMANY reported TACROLIMUS problem on Mar 31, 2008. Male patient, 58 years of age, was diagnosed with stem cell transplant and was treated with TACROLIMUS. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, csf test abnormal, cytomegalovirus infection, deafness, demyelination, disorientation, faecal incontinence, hemianopia homonymous, . TACROLIMUS dosage: 1 MG, BID. During the same period patient was treated with PREDNISOLONE, CYCLOSPORINE. Patient died.

Revlimid Side Effects Report #5708803-8
REVLIMID problem was reported by a Physician from UNITED STATES on Apr 07, 2008. Female patient, 62 years of age, was diagnosed with myelodysplastic syndrome and was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, acute myeloid leukaemia, alpha haemolytic streptococcal infection, amyloidosis, bacterial infection, bone marrow transplant, febrile neutropenia, hepatotoxicity, thrombocytopenia, . REVLIMID dosage: 5 MG, 1 IN 1 D, ORAL, 10 MG, 1 IN 1 D, ORAL. Patient died on 12/02/2007.

Progesterone Side Effects Report #5711212-9
Consumer or non-health professional from ISRAEL reported PROGESTERONE problem on Apr 11, 2008. Female patient, 25 years of age, was diagnosed with amenorrhoea, stem cell transplant and was treated with PROGESTERONE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, conjunctivitis, . PROGESTERONE dosage: DAILY DOSE: 200 MILLIGRAM(S). During the same period patient was treated with DONOR LYMPHOCYTE INFUSIONS. Patient recovered.

Prograf Side Effects Report #5728738-4
PROGRAF problem was reported by a Health Professional from GERMANY on Apr 15, 2008. Male patient, 58 years of age, was diagnosed with prophylaxis against graft versus host disease, chronic lymphocytic leukaemia and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, cytomegalovirus infection, jc virus infection, progressive multifocal leukoencephalopathy, . PROGRAF dosage: 1 MG, BID,. During the same period patient was treated with CAMPATH, FLUDARABINE PHOSPHATE, BUSULFAN, CYCLOSPORINE. Patient died.

Prograf Side Effects Report #5353655-1
Physician from JAPAN reported PROGRAF problem on May 28, 2007. Female patient, child 10 years of age, weighting 83.78 lb, was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, anaemia, back pain, cystitis haemorrhagic, encephalopathy, enterocolitis haemorrhagic, grand mal convulsion, immunosuppression, . PROGRAF dosage: 1.2 MG, CONTINUOUS, IV DRIP. During the same period patient was treated with FUNGIZONEECTION, PREDNISOLONE, BUSULFAN, ETOPOSIDE, NIMUSTINE HYDROCHLORIDE. Patient died on 01/11/2000.