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Forteo Side Effects Report #5677524-2
Physician from CANADA reported FORTEO problem on Mar 12, 2008. Male patient, 49 years of age, was diagnosed with osteoporosis and was treated with FORTEO. After drug was administered, patient experienced the following problems/side effects: amputation, blood test abnormal, impaired healing, limb discomfort, lupus vasculitis, . FORTEO dosage: unknown. During the same period patient was treated with EFFEXOR, VITAMIN B, ROCALTROL, CRESTOR, PARIET, PREDNISONE, FOLIC ACID, SYNTHROID. Patient was hospitalized and became disabled. Patient died on 03/18/2008.

Ambisome Side Effects Report #5679566-X
AMBISOME problem was reported by a Physician from ITALY on Mar 07, 2008. Female patient, 39 years of age, was diagnosed with soft tissue infection and was treated with AMBISOME. After drug was administered, patient experienced the following problems/side effects: amputation, kidney infection, pancytopenia, soft tissue infection, . AMBISOME dosage: 4.5 MG/KG, UID/QD, IV NOS. Patient was hospitalized. Patient recovered.

Naprosyn Side Effects Report #5684707-4
Physician from UNITED STATES reported NAPROSYN problem on June 30, 1982. Female patient, 60 years of age, was treated with NAPROSYN. After drug was administered, patient experienced the following problems/side effects: amputation, ecchymosis, gangrene, pain, petechiae, pyrexia, radial nerve palsy, vasculitis, . NAPROSYN dosage: unknown. During the same period patient was treated with GOLD NOS, PENICILLAMINE, ASPIRIN, BUFFERIN, NALFON. Patient died.

Nexium Side Effects Report #5593668-8
NEXIUM problem was reported by a Consumer or non-health professional from CANADA on Jan 11, 2008. Male patient, 86 years of age, was diagnosed with gastrooesophageal reflux disease, pain and was treated with NEXIUM. After drug was administered, patient experienced the following problems/side effects: amputation, spinal column stenosis, . NEXIUM dosage: unknown. During the same period patient was treated with TYLENOL. Patient was hospitalized. Patient recovered.


Fabrazyme Side Effects Report #5605453-9
Physician from POLAND reported FABRAZYME problem on Jan 09, 2008. Male patient was diagnosed with fabry's disease and was treated with FABRAZYME. After drug was administered, patient experienced the following problems/side effects: amputation, bone density decreased, cardiac valve disease, chills, dyspnoea, extremity necrosis, heart valve incompetence, impaired healing, inflammation, . FABRAZYME dosage: 1 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with ACETYLSALICYLIC ACID SRT, STEROIDS, METHYLPREDNISOLONE, ACETAMINOPHEN, ACE INHIBITOR NOS, BETA BLOCKING AGENTS, STATIN. Patient was hospitalized. Patient recovered.

Zoledronic Side Effects Report #5556890-2
ZOLEDRONIC ACID problem was reported by a Physician from ARGENTINA on Dec 14, 2007. Female patient, 56 years of age, weighting 179.7 lb, was diagnosed with osteoporotic fracture, type 2 diabetes mellitus, hypothyroidism and was treated with ZOLEDRONIC ACID. After drug was administered, patient experienced the following problems/side effects: amputation, concomitant disease progression, diabetes mellitus, enterococcal infection, morganella infection, osteomyelitis, skin ulcer, . ZOLEDRONIC ACID dosage: unknown. During the same period patient was treated with ZOLEDRONIC ACID, CALCIUM CARBONATE, VITAMIN D, GLYBURIDE, LEVOTIROXINA. Patient was hospitalized. Patient recovered.

Zoledronic Side Effects Report #5572882-1
Physician from UNITED STATES reported ZOLEDRONIC ACID problem on Dec 22, 2007. Male patient, 84 years of age, weighting 240.3 lb, was diagnosed with osteoporotic fracture and was treated with ZOLEDRONIC ACID. After drug was administered, patient experienced the following problems/side effects: amputation, arterial occlusive disease, cellulitis, diabetes mellitus, diabetic foot, disease progression, infection, osteomyelitis, . ZOLEDRONIC ACID dosage: unknown. During the same period patient was treated with ZOLEDRONIC ACID, VITAMIN D, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.

Alkeran Side Effects Report #5579975-3
ALKERAN problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 21, 2007. Female patient, 83 years of age, was diagnosed with sarcoma and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: amputation, soft tissue necrosis, . ALKERAN dosage: 1 MG/KG. During the same period patient was treated with TUMOR NECROSIS FACTORECTION, HEPARIN, PROTAMINE SULPHATE. Patient was hospitalized and became disabled. Patient recovered.

Voriconazole Side Effects Report #5511728-4
Consumer or non-health professional from FRANCE reported VORICONAZOLE problem on Oct 30, 2007. Female patient, 84 years of age, was treated with VORICONAZOLE. After drug was administered, patient experienced the following problems/side effects: amputation, fracture, loss of consciousness, osteoarthritis, osteolysis, osteomyelitis, . VORICONAZOLE dosage: unknown. Patient died.


Dianeal Side Effects Report #5517420-4
DIANEAL problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 05, 2007. Male patient, 71 years of age, was diagnosed with peritoneal dialysis, gastrooesophageal reflux disease and was treated with DIANEAL. After drug was administered, patient experienced the following problems/side effects: amputation, asthenia, cellulitis, malaise, sepsis, . DIANEAL dosage: unknown. During the same period patient was treated with POTASSIUM CHLORIDE, GLIMEPIRIDE, COLCHICINE, COLACE, PROTONIX, NORVASC, LOVENOX. Patient was hospitalized. Patient recovered.

Dianeal Side Effects Report #5517422-8
Consumer or non-health professional from UNITED STATES reported DIANEAL problem on Nov 05, 2007. Male patient, 71 years of age, was diagnosed with peritoneal dialysis, gastrooesophageal reflux disease and was treated with DIANEAL. After drug was administered, patient experienced the following problems/side effects: amputation, asthenia, cellulitis, malaise, sepsis, . DIANEAL dosage: unknown. During the same period patient was treated with POTASSIUM CHLORIDE, GLIMEPIRIDE, COLCHICINE, COLACE, PROTONIX, NORVASC, LOVENOX. Patient was hospitalized. Patient recovered.

Seroquel Side Effects Report #5521257-X
SEROQUEL problem was reported by a Health Professional from UNITED STATES on June 20, 2007. Male patient, weighting 207.5 lb, was diagnosed with stress, depression and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: amputation, cardiac disorder, cardiac operation, diabetes mellitus, emotional distress, poor peripheral circulation, . SEROQUEL dosage: unknown. During the same period patient was treated with CLOZARIL, ZOLOFT, RISPERDAL. Patient recovered.

Azathioprine Side Effects Report #5487353-0
Consumer or non-health professional from reported AZATHIOPRINE problem on Oct 10, 2007. Female patient, 84 years of age, was diagnosed with pemphigoid and was treated with AZATHIOPRINE. After drug was administered, patient experienced the following problems/side effects: amputation, cryptococcal cutaneous infection, meningitis, osteomyelitis acute, renal impairment, . AZATHIOPRINE dosage: unknown. During the same period patient was treated with PREDNISONE, LEVOTHYROXINE, SPIRONOLACTONE, WARFARIN, ATORVASTATIN CALCIUM, DOXYCYCLINE, LANSOPRAZOLE, ASPIRIN. Patient was hospitalized. Patient died.

Prempro Side Effects Report #5501465-4
PREMPRO problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 19, 2007. Female patient, weighting 240.2 lb, was diagnosed with hot flush, insomnia and was treated with PREMPRO. After drug was administered, patient experienced the following problems/side effects: amputation, arterial thrombosis limb, cerebrovascular accident, . PREMPRO dosage: unknown. During the same period patient was treated with PREMARIN. Patient recovered.


Activase Side Effects Report #5445674-1
Health Professional from GERMANY reported ACTIVASE problem on Sept 06, 2007. Female patient was diagnosed with arterial thrombosis and was treated with ACTIVASE. After drug was administered, patient experienced the following problems/side effects: amputation, . ACTIVASE dosage: 3 MG/KG/H, 6 HOURS PER DAY. During the same period patient was treated with HEPARIN. Patient recovered.

Chantix Side Effects Report #5457178-0
CHANTIX problem was reported by a Physician from UNITED STATES on Sept 06, 2007. Male patient, weighting 199.1 lb, was diagnosed with nicotine dependence and was treated with CHANTIX. After drug was administered, patient experienced the following problems/side effects: amputation, hypertension, hypotonia, necrosis, pain, peripheral vascular disorder, . CHANTIX dosage: unknown. During the same period patient was treated with VERELAN PM, ATACAND, HYDROCHLOROTHIAZIDE, TOPROL. Patient recovered.

Thalomid Side Effects Report #5407840-0
Physician from UNITED STATES reported THALOMID problem on July 24, 2007. Male patient, 55 years of age, was diagnosed with multiple myeloma and was treated with THALOMID. After drug was administered, patient experienced the following problems/side effects: amputation, cellulitis, osteomyelitis, ulcer, . THALOMID dosage: 200 MG, 1 IN 1 D, ORAL. During the same period patient was treated with DECADRON, ZOCOR, ZYPREXA, LITHIUM CARBONATE, CALCIUM WITH D. Patient recovered.

Chantix Side Effects Report #5408775-X
CHANTIX problem was reported by a Physician from UNITED STATES on July 27, 2007. Male patient, weighting 199.1 lb, was diagnosed with nicotine dependence and was treated with CHANTIX. After drug was administered, patient experienced the following problems/side effects: amputation, hypertension, hypotonia, necrosis, peripheral vascular disorder, . CHANTIX dosage: unknown. During the same period patient was treated with VERELAN PM, ATACAND, HYDROCHLOROTHIAZIDE, TOPROL. Patient recovered.

Tracleer Side Effects Report #5427661-2
Consumer or non-health professional from UNITED KINGDOM reported TRACLEER problem on Aug 08, 2007. Male patient, 38 years of age, was diagnosed with pulmonary hypertension and was treated with TRACLEER. After drug was administered, patient experienced the following problems/side effects: amputation, anaemia, cyanosis, disease progression, gangrene, infarction, ischaemia, microangiopathy, sclerodactylia, . TRACLEER dosage: 62.5 MG, BID, ORAL; 125 MG, BID. During the same period patient was treated with VENTAVIS, NIFEDIPINE, CLOPIDOGREL, FLUOXETINE, LANSOPRAZOLE, METHYLPREDNISOLONE, CYCLOPHOSPHAMIDE, LOSARTAN POTASSIUM. Patient was hospitalized. Patient recovered.


Avonex Side Effects Report #5442005-8
AVONEX problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 20, 2007. Female patient, 60 years of age, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: amputation, metastases to lymph nodes, metastasis, metastatic malignant melanoma, . AVONEX dosage: unknown. Patient was hospitalized. Patient recovered.

Seroquel Side Effects Report #5383376-0
Health Professional from UNITED STATES reported SEROQUEL problem on July 02, 2007. Female patient, 72 years of age, weighting 140.2 lb, was diagnosed with schizophrenia and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: amputation, diabetic ketoacidosis, type 2 diabetes mellitus, . SEROQUEL dosage: 100-300 MG. During the same period patient was treated with THORAZINE, ZYPREXA. Patient was hospitalized. Patient recovered.

Cisplatin Side Effects Report #5395411-4
CISPLATIN problem was reported by a Health Professional from UNITED STATES on July 23, 2007. Male patient, 48 years of age, was diagnosed with pancreatic carcinoma and was treated with CISPLATIN. After drug was administered, patient experienced the following problems/side effects: amputation, pneumonia, raynaud's phenomenon, . CISPLATIN dosage: unknown. During the same period patient was treated with GEMCITABINE, HYPERBARIC OXYGEN. Patient died.

Cubicin Side Effects Report #5397150-2
Physician from UNITED STATES reported CUBICIN problem on July 06, 2007. Female patient, 61 years of age, was diagnosed with arthritis infective and was treated with CUBICIN. After drug was administered, patient experienced the following problems/side effects: amputation, decubitus ulcer, fracture, hip disarticulation, post procedural complication, skin ulcer, treatment noncompliance, wound dehiscence, wound drainage, . CUBICIN dosage: 6 MG/KG;Q24H;. During the same period patient was treated with LEVOFLOXACIN. Patient recovered.

Cisplatin Side Effects Report #5399395-4
CISPLATIN problem was reported by a Health Professional from UNITED STATES on July 26, 2007. Male patient, 48 years of age, was diagnosed with pancreatic carcinoma and was treated with CISPLATIN. After drug was administered, patient experienced the following problems/side effects: amputation, pneumonia, raynaud's phenomenon, . CISPLATIN dosage: unknown. During the same period patient was treated with GEMCITABINE, HYPERBARIC OXYGEN. Patient died.

Activase Side Effects Report #5401945-6
Health Professional from GERMANY reported ACTIVASE problem on July 26, 2007. Female patient was diagnosed with arterial thrombosis and was treated with ACTIVASE. After drug was administered, patient experienced the following problems/side effects: amputation, . ACTIVASE dosage: 3 MG/KG/H, 6 HOURS PER DAY. During the same period patient was treated with HEPARIN. Patient recovered.

Seroquel Side Effects Report #5383376-0
SEROQUEL problem was reported by a Health Professional from UNITED STATES on July 02, 2007. Female patient, 72 years of age, weighting 140.2 lb, was diagnosed with schizophrenia and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: amputation, diabetic ketoacidosis, type 2 diabetes mellitus, . SEROQUEL dosage: 100-300 MG. During the same period patient was treated with THORAZINE, ZYPREXA. Patient was hospitalized. Patient recovered.

Cisplatin Side Effects Report #5395411-4
Health Professional from UNITED STATES reported CISPLATIN problem on July 23, 2007. Male patient, 48 years of age, was diagnosed with pancreatic carcinoma and was treated with CISPLATIN. After drug was administered, patient experienced the following problems/side effects: amputation, pneumonia, raynaud's phenomenon, . CISPLATIN dosage: unknown. During the same period patient was treated with GEMCITABINE, HYPERBARIC OXYGEN. Patient died.

Cubicin Side Effects Report #5397150-2
CUBICIN problem was reported by a Physician from UNITED STATES on July 06, 2007. Female patient, 61 years of age, was diagnosed with arthritis infective and was treated with CUBICIN. After drug was administered, patient experienced the following problems/side effects: amputation, decubitus ulcer, fracture, hip disarticulation, post procedural complication, skin ulcer, treatment noncompliance, wound dehiscence, wound drainage, . CUBICIN dosage: 6 MG/KG;Q24H;. During the same period patient was treated with LEVOFLOXACIN. Patient recovered.

Cisplatin Side Effects Report #5399395-4
Health Professional from UNITED STATES reported CISPLATIN problem on July 26, 2007. Male patient, 48 years of age, was diagnosed with pancreatic carcinoma and was treated with CISPLATIN. After drug was administered, patient experienced the following problems/side effects: amputation, pneumonia, raynaud's phenomenon, . CISPLATIN dosage: unknown. During the same period patient was treated with GEMCITABINE, HYPERBARIC OXYGEN. Patient died.

Activase Side Effects Report #5401945-6
ACTIVASE problem was reported by a Health Professional from GERMANY on July 26, 2007. Female patient was diagnosed with arterial thrombosis and was treated with ACTIVASE. After drug was administered, patient experienced the following problems/side effects: amputation, . ACTIVASE dosage: 3 MG/KG/H, 6 HOURS PER DAY. During the same period patient was treated with HEPARIN. Patient recovered.

Seroquel Side Effects Report #5765621-2
Consumer or non-health professional from UNITED STATES reported SEROQUEL problem on June 05, 2008. Female patient, 72 years of age, weighting 140.2 lb, was diagnosed with schizophrenia, depression and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: amputation, diabetic ketoacidosis, type 2 diabetes mellitus, . SEROQUEL dosage: 100-300 MG. During the same period patient was treated with THORAZINE, ZYPREXA. Patient recovered.

Keppra Side Effects Report #5729889-0
KEPPRA problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 18, 2008. Male patient was diagnosed with convulsion and was treated with KEPPRA. After drug was administered, patient experienced the following problems/side effects: amputation, . KEPPRA dosage: 750 MG 2/D. Patient recovered.

Erbitux Side Effects Report #5708227-3
Consumer or non-health professional from GERMANY reported ERBITUX problem on Apr 11, 2008. Female patient, 69 years of age, was diagnosed with colorectal cancer metastatic and was treated with ERBITUX. After drug was administered, patient experienced the following problems/side effects: amputation, . ERBITUX dosage: unknown. Patient was hospitalized. Patient recovered.

Humulin Side Effects Report #5716579-3
HUMULIN N problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 17, 2008. Female patient was treated with HUMULIN N. After drug was administered, patient experienced the following problems/side effects: amputation, blood glucose increased, . HUMULIN N dosage: unknown. During the same period patient was treated with HUMULIN N, HUMULIN N, GLUCOPHAGE. Patient recovered.

Tnkase Side Effects Report #5358846-1
Physician from GERMANY reported TNKASE problem on June 08, 2007. Female patient was diagnosed with peripheral ischaemia and was treated with TNKASE. After drug was administered, patient experienced the following problems/side effects: amputation, . TNKASE dosage: 0.25 MG/HR, UNK. During the same period patient was treated with HEPARIN. Patient recovered.

Humalog Side Effects Report #5382549-0
HUMALOG problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 20, 2007. Male patient, 50 years of age, was diagnosed with diabetes mellitus and was treated with HUMALOG. After drug was administered, patient experienced the following problems/side effects: amputation, coronary artery disease, myocardial infarction, peripheral vascular disorder, thrombosis, . HUMALOG dosage: unknown. Patient was hospitalized. Patient recovered.

Angiomax Side Effects Report #5330888-1
Consumer or non-health professional from UNITED STATES reported ANGIOMAX problem on May 04, 2007. Female patient was diagnosed with heparin-induced thrombocytopenia and was treated with ANGIOMAX. After drug was administered, patient experienced the following problems/side effects: amputation, cerebrovascular accident, deep vein thrombosis, ecchymosis, epistaxis, eye haemorrhage, haematuria, haemoglobin decreased, . ANGIOMAX dosage: unknown. During the same period patient was treated with ARGATROBAN, LEPIRUDIN, HEPARIN. Patient died.

Cafergot Side Effects Report #5290566-4
CAFERGOT problem was reported by a Health Professional from UNITED KINGDOM on Mar 27, 2007. Male patient, 69 years of age, was diagnosed with migraine and was treated with CAFERGOT. After drug was administered, patient experienced the following problems/side effects: amputation, hypertension, . CAFERGOT dosage: unknown. During the same period patient was treated with PREDNISOLONE, FLUDROCORTISONE ACETATE, INSULIN LISPRO, INSULIN INSULATARD, ASPIRIN, DOXYCYCLINE, RIFAMPICIN. Patient was hospitalized. Patient recovered.

Tamoxifen Side Effects Report #5300442-6
Consumer or non-health professional from UNITED STATES reported TAMOXIFEN CITRATE problem on Apr 13, 2007. Female patient, weighting 120.0 lb, was diagnosed with breast cancer and was treated with TAMOXIFEN CITRATE. After drug was administered, patient experienced the following problems/side effects: amputation, foot amputation, gangrene, sepsis, thrombosis, . TAMOXIFEN CITRATE dosage: 20MG QD PO. Patient was hospitalized and became disabled. Patient recovered.

Remicade Side Effects Report #5310465-9
REMICADE problem was reported by a Pharmacist from CANADA on Apr 19, 2007. Male patient was diagnosed with crohn's disease and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: amputation, injury, . REMICADE dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient recovered.

Seroquel Side Effects Report #5261846-3
Health Professional from UNITED STATES reported SEROQUEL problem on Feb 28, 2007. Male patient, weighting 207.5 lb, was diagnosed with stress, depression and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: amputation, cardiac disorder, diabetes mellitus, emotional distress, poor peripheral circulation, . SEROQUEL dosage: unknown. During the same period patient was treated with CLOZARIL, ZOLOFT, RISPERDAL. Patient recovered.

Valsartan Side Effects Report #5278269-3
VALSARTAN AND HYDROCHLOROTHIAZIDE problem was reported by a Consumer or non-health professional from TAIWAN, PROVINCE OF CHINA on Mar 16, 2007. Female patient, 77 years of age, weighting 167.6 lb, was diagnosed with hypertension and was treated with VALSARTAN AND HYDROCHLOROTHIAZIDE. After drug was administered, patient experienced the following problems/side effects: amputation, . VALSARTAN AND HYDROCHLOROTHIAZIDE dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Rebif Side Effects Report #5278460-6
Consumer or non-health professional from UNITED STATES reported REBIF problem on Mar 13, 2007. Female patient, 44 years of age, weighting 225.0 lb, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: amputation, extremity necrosis, raynaud's phenomenon, skin ulcer, splinter haemorrhages, . REBIF dosage: unknown. During the same period patient was treated with AMANTADINE, ASPIRIN, DYAZIDE, NORVASC, NEXIUM, NITRO CREAM, POTASSIUM. Patient recovered.

Innohep Side Effects Report #5797192-9
INNOHEP problem was reported by a Physician from FRANCE on June 12, 2008. Male patient, 78 years of age, weighting 220.5 lb, was diagnosed with thrombosis prophylaxis and was treated with INNOHEP. After drug was administered, patient experienced the following problems/side effects: adrenal insufficiency, amputation, arterial thrombosis, blood lactic acid abnormal, embolism, heparin-induced thrombocytopenia, hepatic failure, multi-organ failure, peripheral ischaemia, . INNOHEP dosage: unknown. During the same period patient was treated with HYZAAR, ACTRAPID. Patient was hospitalized. Patient recovered.

Neurontin Side Effects Report #5254618-7
Health Professional from UNITED STATES reported NEURONTIN problem on Feb 19, 2007. Male patient, weighting 170.0 lb, was diagnosed with pain and was treated with NEURONTIN. After drug was administered, patient experienced the following problems/side effects: aggression, amputation, depression, pain in extremity, stent placement, suicidal behaviour, . NEURONTIN dosage: unknown. During the same period patient was treated with LYRICA, CHANTIX, OXYIR, WARFARIN, ATIVAN, BACLOFEN, TYLENOL, FAMOTIDINE. Patient recovered.