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Gleevec Side Effects Report #5688382-4
Physician from PERU reported GLEEVEC problem on Mar 25, 2008. Male patient, 64 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, leukocytosis, malignant neoplasm progression, pneumonia, systemic candida, thrombocytopenia, thrombophlebitis, . GLEEVEC dosage: 400 MG, QD. Patient was hospitalized. Patient died on 01/01/2008.

Gleevec Side Effects Report #5611248-2
GLEEVEC problem was reported by a Physician from CHINA on Jan 09, 2008. Female patient, 56 years of age, weighting 114.6 lb, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, chronic myeloid leukaemia, conjunctivitis, deafness, hypoacusis, platelet count increased, pyrexia, white blood cell count increased, . GLEEVEC dosage: 400 MG/ DAY. Patient was hospitalized and became disabled. Patient recovered.

Gleevec Side Effects Report #5629807-X
Physician from UNITED STATES reported GLEEVEC problem on Feb 13, 2008. Male patient, 49 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, cerebral infarction, disease progression, fungal infection, . GLEEVEC dosage: 600MG, QD. Patient was hospitalized. Patient died on 12/16/2007.

Imatinib Side Effects Report #5604034-0
IMATINIB problem was reported by a Health Professional from JAPAN on Jan 14, 2008. Male patient, 35 years of age, was diagnosed with chronic myeloid leukaemia and was treated with IMATINIB. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, chromosome analysis abnormal, disseminated intravascular coagulation, fibrin d dimer increased, fibrin degradation products, haemorrhagic diathesis, hypovolaemic shock, malignant neoplasm progression, petechiae, . IMATINIB dosage: 600 MG/D. During the same period patient was treated with DANAPAROID. Patient was hospitalized. Patient recovered.


Imatinib Side Effects Report #5608989-X
Health Professional from MALTA reported IMATINIB problem on Jan 25, 2008. Male patient was diagnosed with chronic myeloid leukaemia and was treated with IMATINIB. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, bone marrow failure, gastrointestinal haemorrhage, lung infection, malignant neoplasm progression, myelodysplastic syndrome, pancytopenia, pulmonary haemorrhage, thrombocytopenia, . IMATINIB dosage: 600 MG/D. Patient died.

Cyclosporine Side Effects Report #5486276-0
CYCLOSPORINE problem was reported by a Consumer or non-health professional from JAPAN on Oct 10, 2007. Female patient, 54 years of age, was diagnosed with stem cell transplant, acute graft versus host disease in liver and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, cd4 lymphocytes decreased, cerebral toxoplasmosis, csf protein increased, csf white blood cell count increased, headache, nuchal rigidity, pneumonia bacterial, pseudomonal sepsis, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with PREDNISOLONE, SULFAMETHOXAZOLE W. Patient died.

Cyclosporine Side Effects Report #5494605-7
Health Professional from JAPAN reported CYCLOSPORINE problem on Oct 22, 2007. Female patient, 54 years of age, was diagnosed with stem cell transplant, acute graft versus host disease in liver and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, cd4 lymphocytes decreased, cerebral toxoplasmosis, csf protein increased, csf white blood cell count increased, headache, nuchal rigidity, pneumonia bacterial, pseudomonal sepsis, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with PREDNISOLONE, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient died.

Exjade Side Effects Report #5466585-1
EXJADE problem was reported by a Physician from FRANCE on Sept 17, 2007. Female patient, 58 years of age, weighting 134.5 lb, was diagnosed with myeloid leukaemia and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, lumbar puncture, metastases to meninges, numb chin syndrome, papilloedema, vision blurred, visual acuity reduced, visual field defect, . EXJADE dosage: 1250 MG, QD. Patient was hospitalized. Patient recovered.

Cyclosporine Side Effects Report #5411970-7
Health Professional from JAPAN reported CYCLOSPORINE problem on Aug 07, 2007. Female patient, 54 years of age, was diagnosed with stem cell transplant, acute graft versus host disease in liver and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, cd4 lymphocytes decreased, cerebral toxoplasmosis, csf protein increased, csf white blood cell count increased, headache, nuchal rigidity, pneumonia bacterial, pseudomonal sepsis, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with PREDNISOLONE, SULFAMETHOXAZOLE W. Patient died.


Cyclosporine Side Effects Report #5412282-8
CYCLOSPORINE problem was reported by a Health Professional from JAPAN on Aug 07, 2007. Female patient, 54 years of age, was diagnosed with stem cell transplant, acute graft versus host disease in liver and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, cd4 lymphocytes decreased, cerebral toxoplasmosis, csf protein increased, csf white blood cell count increased, headache, nuchal rigidity, pneumonia bacterial, pseudomonal sepsis, . CYCLOSPORINE dosage: unknown. During the same period patient was treated with PREDNISOLONE, SULFAMETHOXAZOLE W. Patient died.

Tasigna Side Effects Report #5762321-X
Physician from SLOVAKIA (Slovak Republic) reported TASIGNA problem on May 30, 2008. Male patient, weighting 187.4 lb, was diagnosed with chronic myeloid leukaemia, leukocytosis, hyperuricaemia and was treated with TASIGNA. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, chronic myeloid leukaemia, hyperuricaemia, leukocytosis, thrombocytopenia, . TASIGNA dosage: 800MG. During the same period patient was treated with HYDROXYUREA, MILURIT. Patient was hospitalized. Patient recovered.

Tasigna Side Effects Report #5742225-9
TASIGNA problem was reported by a Physician from SLOVAKIA (Slovak Republic) on May 08, 2008. Male patient, 70 years of age, weighting 187.4 lb, was diagnosed with chronic myeloid leukaemia, leukocytosis, hyperuricaemia and was treated with TASIGNA. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, chronic myeloid leukaemia, hyperuricaemia, leukocytosis, thrombocytopenia, . TASIGNA dosage: 800MG. During the same period patient was treated with HYDROXYUREA, MILURIT. Patient was hospitalized. Patient recovered.

Tasigna Side Effects Report #5762833-9
Health Professional from UNITED STATES reported TASIGNA problem on Apr 24, 2008. Male patient, 47 years of age, was diagnosed with chronic myeloid leukaemia and was treated with TASIGNA. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, cardiac failure, chronic myeloid leukaemia, ejection fraction decreased, infection, . TASIGNA dosage: 400 MG, BID, ORAL. Patient died on 03/01/2008.

Gleevec Side Effects Report #5370640-4
GLEEVEC problem was reported by a Physician from UNITED STATES on Aug 14, 2006. Male patient, 54 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, white blood cell count decreased, . GLEEVEC dosage: 600 MG, QD, ORAL. Patient was hospitalized. Patient recovered.


Gleevec Side Effects Report #5253178-4
Consumer or non-health professional from JAPAN reported GLEEVEC problem on Feb 23, 2007. Male patient, 31 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: blast crisis in myelogenous leukaemia, graft versus host disease, sepsis, stem cell transplant, . GLEEVEC dosage: 400 MG/DAY. Patient was hospitalized. Patient died on 08/01/2005.

Temozolomide Side Effects Report #5678349-4
TEMOZOLOMIDE problem was reported by a Health Professional from UNITED STATES on Mar 13, 2008. Male patient, 78 years of age, weighting 149.9 lb, was diagnosed with acute myeloid leukaemia and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: atrial fibrillation, blast crisis in myelogenous leukaemia, cardiac arrest, cardiac failure, constipation, dialysis, escherichia sepsis, fatigue, febrile neutropenia, . TEMOZOLOMIDE dosage: 180 MG; QD; PO; 370 MG; QD; PO. Patient was hospitalized. Patient died on 03/08/2008.

Tasigna Side Effects Report #5727159-8
Physician from BRAZIL reported TASIGNA problem on Apr 29, 2008. Female patient, 39 years of age, weighting 134.5 lb, was diagnosed with chronic myeloid leukaemia and was treated with TASIGNA. After drug was administered, patient experienced the following problems/side effects: anaemia, blast crisis in myelogenous leukaemia, candidiasis, chronic myeloid leukaemia, dyspnoea, endotracheal intubation complication, fungal infection, headache, . TASIGNA dosage: 800MG DAILY. During the same period patient was treated with VANCOMYCIN. Patient was hospitalized. Patient died on 08/18/2007.

Tasigna Side Effects Report #5737218-1
TASIGNA problem was reported by a Physician from BRAZIL on May 09, 2008. Female patient, 39 years of age, weighting 134.5 lb, was diagnosed with chronic myeloid leukaemia and was treated with TASIGNA. After drug was administered, patient experienced the following problems/side effects: anaemia, blast crisis in myelogenous leukaemia, candidiasis, chronic myeloid leukaemia, dyspnoea, endotracheal intubation complication, fungal infection, headache, . TASIGNA dosage: 800MG DAILY. During the same period patient was treated with VANCOMYCIN. Patient was hospitalized. Patient died on 08/18/2007.

Gleevec Side Effects Report #5332524-7
Consumer or non-health professional from JAPAN reported GLEEVEC problem on May 11, 2007. Male patient, 61 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: arthralgia, blast crisis in myelogenous leukaemia, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone cancer metastatic, bone marrow failure, c-reactive protein increased, dyspnoea, . GLEEVEC dosage: 300 MG/DAY. Patient was hospitalized. Patient recovered.


Gleevec Side Effects Report #5303149-4
GLEEVEC problem was reported by a Consumer or non-health professional from JAPAN on Apr 06, 2007. Male patient, 61 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: arthralgia, blast crisis in myelogenous leukaemia, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, bone cancer metastatic, bone marrow failure, c-reactive protein increased, dyspnoea, . GLEEVEC dosage: 300 MG/DAY. Patient was hospitalized. Patient recovered.

Lasix Side Effects Report #5271231-6
Consumer or non-health professional from UNITED STATES reported LASIX problem on Mar 09, 2007. Female patient, 31 years of age, was diagnosed with chronic myeloid leukaemia and was treated with LASIX. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, blast crisis in myelogenous leukaemia, deep vein thrombosis, splenic rupture, weight increased, white blood cell count increased, . LASIX dosage: 20 MG, PRN. During the same period patient was treated with GLEEVEC. Patient was hospitalized. Patient recovered.

Lasix Side Effects Report #5275686-2
LASIX problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 19, 2007. Female patient, 31 years of age, was diagnosed with chronic myeloid leukaemia and was treated with LASIX. After drug was administered, patient experienced the following problems/side effects: acute myeloid leukaemia, blast crisis in myelogenous leukaemia, cardiac arrest, deep vein thrombosis, platelet count decreased, pneumonia, pulmonary haemorrhage, splenic rupture, weight increased, . LASIX dosage: 20 MG, PRN. During the same period patient was treated with GLEEVEC. Patient was hospitalized. Patient died on 03/14/2007.

Gleevec Side Effects Report #5445891-0
Consumer or non-health professional from UNITED STATES reported GLEEVEC problem on Sept 05, 2007. Female patient, 80 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: asthenia, back pain, blast crisis in myelogenous leukaemia, cardiac disorder, cardiac failure, cerebrovascular accident, colonoscopy abnormal, coronary artery disease, diabetes mellitus, . GLEEVEC dosage: unknown. During the same period patient was treated with INSULIN. Patient was hospitalized. Patient died on 07/18/2007.

Gleevec Side Effects Report #5403652-2
GLEEVEC problem was reported by a Consumer or non-health professional from UNITED STATES on July 29, 2007. Female patient, 80 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: asthenia, back pain, blast crisis in myelogenous leukaemia, cardiac failure, cerebrovascular accident, colonoscopy abnormal, diabetes mellitus, dyspnoea, . GLEEVEC dosage: unknown. During the same period patient was treated with INSULIN. Patient was hospitalized. Patient died on 07/18/2007.

Gleevec Side Effects Report #5370674-X
Consumer or non-health professional from UNITED STATES reported GLEEVEC problem on Sept 22, 2006. Male patient, 45 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: abdominal distension, arthralgia, blast crisis in myelogenous leukaemia, chills, confusional state, constipation, eye disorder, fatigue, fluid retention, . GLEEVEC dosage: 400 MG, QD, ORAL. Patient was hospitalized. Patient recovered.

Gleevec Side Effects Report #5257631-9
GLEEVEC problem was reported by a Health Professional from ITALY on Feb 28, 2007. Male patient, 50 years of age, was diagnosed with chronic myeloid leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: asthenia, blast cells present, blast crisis in myelogenous leukaemia, cerebral haemorrhage, disseminated intravascular coagulation, haemoglobin decreased, platelet count decreased, white blood cell count decreased, . GLEEVEC dosage: 400 MG/D. Patient died.