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BONE MARROW TOXICITY side effect

What is BONE MARROW TOXICITY ?
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Drugs associated with BONE MARROW TOXICITY

AVASTIN  AZATHIOPRINE  CYCLOPHOSPHAMIDE ERLOTINIB  ETOPOSIDE  EXJADE  HUMIRA  LEFLUNOMIDE  MABTHERA  MEMANTINE  METHOTREXATE  NABUCOX  NOVATREX  PREDNISOLONE  PROGRAF  REVLIMID  STAVUDINE  TAXOTERE  TAZOCILLINE  TEMOZOLOMIDE  THYROGEN  VELCADE  ZEVALIN  


Memantine Side Effects Report #5650243-4
Consumer or non-health professional from ITALY reported MEMANTINE problem on Feb 14, 2008. Male patient, 83 years of age, was diagnosed with dementia alzheimer's type and was treated with MEMANTINE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, condition aggravated, erythropenia, influenza, leukopenia, myocardial infarction, pulmonary embolism, thrombocytopenia, . MEMANTINE dosage: 20 MG QD;PO. During the same period patient was treated with METFORMIN, RAMIPRIL, TRAZODONE. Patient recovered.

Azathioprine Side Effects Report #5663673-1
AZATHIOPRINE problem was reported by a Physician from UNITED KINGDOM on Feb 25, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with AZATHIOPRINE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cerebellar syndrome, cystitis haemorrhagic, disease recurrence, dysphagia, herpes zoster, jc virus infection, neutrophil count decreased, no therapeutic response, . AZATHIOPRINE dosage: unknown. During the same period patient was treated with PREDNISOLONE, RITUXIMAB, CYCLOPHOSPHAMIDE. Patient died.

Azathioprine Side Effects Report #5671843-1
Consumer or non-health professional from UNITED KINGDOM reported AZATHIOPRINE problem on Feb 26, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with AZATHIOPRINE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cystitis haemorrhagic, jc virus infection, progressive multifocal leukoencephalopathy, respiratory failure, weight decreased, . AZATHIOPRINE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, RITUXIMAB, PREDNISOLONE. Patient died.

Memantine Side Effects Report #5677450-9
MEMANTINE problem was reported by a Health Professional from GERMANY on Mar 03, 2008. Male patient, 83 years of age, was diagnosed with dementia alzheimer's type and was treated with MEMANTINE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, dehydration, dementia, incontinence, influenza, leukopenia, myocardial infarction, pulmonary embolism, red blood cell count decreased, . MEMANTINE dosage: 20 MG QD PO. During the same period patient was treated with METFORMIN, RAMIPRIL, TRAZODONE. Patient died on 01/26/2008.


Prednisolone Side Effects Report #5685309-6
Consumer or non-health professional from UNITED KINGDOM reported PREDNISOLONE problem on Mar 20, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with PREDNISOLONE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cystitis haemorrhagic, dysphagia, herpes zoster, pneumonia, progressive multifocal leukoencephalopathy, respiratory failure, weight decreased, . PREDNISOLONE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, RITUXIMAB, CORTICOSTEROIDS. Patient died.

Memantine Side Effects Report #5619270-7
MEMANTINE problem was reported by a Health Professional from ITALY on Jan 22, 2008. Male patient, 83 years of age, was diagnosed with dementia alzheimer's type and was treated with MEMANTINE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, fibrin d dimer increased, haematocrit decreased, haemoglobin decreased, leukopenia, red blood cell count decreased, thrombocytopenia, . MEMANTINE dosage: 20 MG QD PO. During the same period patient was treated with METFORMIN, RAMIPRIL, TRAZODONE. Patient recovered.

Avastin Side Effects Report #5620553-5
Physician from UNITED KINGDOM reported AVASTIN problem on Jan 25, 2008. Female patient, weighting 138.9 lb, was diagnosed with breast cancer and was treated with AVASTIN. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, disseminated intravascular coagulation, febrile bone marrow aplasia, hepatocellular injury, mucosal inflammation, staphylococcal infection, . AVASTIN dosage: unknown. During the same period patient was treated with TAXOL. Patient recovered.

Memantine Side Effects Report #5611848-X
MEMANTINE problem was reported by a Consumer or non-health professional from ITALY on Jan 16, 2008. Male patient, 83 years of age, was treated with MEMANTINE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, haematocrit decreased, haemoglobin decreased, leukopenia, red blood cell count decreased, thrombocytopenia, . MEMANTINE dosage: 20 MG QD PO. During the same period patient was treated with METFORMIN, RAMIPRIL, TRAZODONE. Patient recovered.

Zevalin Side Effects Report #5550376-7
Physician from POLAND reported ZEVALIN problem on Dec 10, 2007. Female patient, 66 years of age, was diagnosed with mantle cell lymphoma recurrent and was treated with ZEVALIN. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, haemorrhage intracranial, thrombocytopenia, . ZEVALIN dosage: unknown. During the same period patient was treated with RITUXIMAB, FLUDARA. Patient died on 10/20/2005.


Leflunomide Side Effects Report #5447464-2
LEFLUNOMIDE problem was reported by a Physician from AUSTRIA on Aug 21, 2007. Female patient, 64 years of age, was diagnosed with rheumatoid arthritis and was treated with LEFLUNOMIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, leukopenia, lymphopenia, myelodysplastic syndrome, neutropenia, pyrexia, stomatitis, . LEFLUNOMIDE dosage: 10 MG, 20 MG. During the same period patient was treated with METAMIZOLE. Patient was hospitalized. Patient recovered.

Erlotinib Side Effects Report #5468390-9
Physician from FRANCE reported ERLOTINIB problem on Sept 07, 2007. Male patient, 60 years of age, was diagnosed with non-small cell lung cancer and was treated with ERLOTINIB. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, neutropenia, . ERLOTINIB dosage: 300 MG (QD), ORAL. During the same period patient was treated with MINOCIN, ADVIL, TOLEXINE. Patient was hospitalized. Patient recovered.

Erlotinib Side Effects Report #5423094-3
ERLOTINIB problem was reported by a Physician from FRANCE on Aug 06, 2007. Male patient, 60 years of age, was diagnosed with non-small cell lung cancer and was treated with ERLOTINIB. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, lymphocyte count decreased, monocyte count decreased, neutropenia, unevaluable event, white blood cell count decreased, . ERLOTINIB dosage: 300 MG (QD), ORAL. During the same period patient was treated with MINOCIN, ADVIL. Patient was hospitalized. Patient recovered.

Revlimid Side Effects Report #5781378-3
Consumer or non-health professional from UNITED STATES reported REVLIMID problem on June 10, 2008. Female patient was diagnosed with multiple myeloma and was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cerebral infarction, constipation, disease progression, fatigue, graft versus host disease, haematotoxicity, infection, leukopenia, . REVLIMID dosage: 25 MG, DAILY ON DAYS 1-21 EVERY 28 DAYS, ORAL, 10 MG, DAILY ON DAYS 1-21 EVERY 28 DAYS, ORAL. During the same period patient was treated with CORTICOSTEROIDS. Patient died.

Humira Side Effects Report #5743243-7
HUMIRA problem was reported by a Consumer or non-health professional from GERMANY on May 09, 2008. Female patient, 71 years of age, weighting 136.7 lb, was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, leukopenia, . HUMIRA dosage: unknown. During the same period patient was treated with ETANERCEPT, PROPIVERINE HYDROCHLORIDE, ATENOLOL, BUFLOMEDIL HYDROCHLORIDE, CITALOPRAM HYDROBROMIDE, LEKOVIT CA, ACTONEL. Patient was hospitalized. Patient recovered.


Prednisolone Side Effects Report #5694387-X
Health Professional from UNITED KINGDOM reported PREDNISOLONE problem on Mar 17, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with PREDNISOLONE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cystitis haemorrhagic, herpes zoster, jc virus infection, neutrophil count decreased, pneumonia, progressive multifocal leukoencephalopathy, respiratory failure, vision blurred, . PREDNISOLONE dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOPHOSPHAMIDE, RITUXIMAB. Patient died.

Mabthera Side Effects Report #5695032-X
MABTHERA problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 25, 2008. Female patient was diagnosed with systemic lupus erythematosus, raynaud's phenomenon, osteoporosis, hypothyroidism, hypersensitivity, premature menopause and was treated with MABTHERA. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, progressive multifocal leukoencephalopathy, respiratory failure, . MABTHERA dosage: 375 MG/M2, 1/WEEK. During the same period patient was treated with AMLODIPINE, CALCICHEW D, HYDROXYCHLOROQUINE, LEVOTHYROXINE, CLARITIN, NUVELLE. Patient died on 07/10/2006.

Prednisolone Side Effects Report #5695127-0
Consumer or non-health professional from UNITED KINGDOM reported PREDNISOLONE problem on Mar 27, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with PREDNISOLONE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cystitis haemorrhagic, herpes zoster, pneumonia, progressive multifocal leukoencephalopathy, respiratory failure, weight decreased, . PREDNISOLONE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, RITUXIMAB. Patient died.

Prednisolone Side Effects Report #5716996-1
PREDNISOLONE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 18, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with PREDNISOLONE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cystitis haemorrhagic, herpes zoster, pneumonia, progressive multifocal leukoencephalopathy, respiratory failure, weight decreased, . PREDNISOLONE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, AZATHIOPRINE, RITUXIMAB, AMLODIPINE, CALCICHEW, CLARYTINE, FOLIC ACID, HYDROXYCHLOROQUINE SULPHATE. Patient died on 07/10/2006.

Tazocilline Side Effects Report #5361480-0
Health Professional from FRANCE reported TAZOCILLINE problem on June 14, 2007. Female patient, 68 years of age, was treated with TAZOCILLINE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, granulocytes abnormal, megakaryocytes abnormal, pancytopenia, pyrexia, respiratory distress, . TAZOCILLINE dosage: unknown. During the same period patient was treated with MOTILIUM, TRIFLUCAN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.


Taxotere Side Effects Report #5262360-1
TAXOTERE problem was reported by a Consumer or non-health professional from ITALY on Feb 27, 2007. Male patient, 62 years of age, weighting 138.9 lb, was diagnosed with non-small cell lung cancer and was treated with TAXOTERE. After drug was administered, patient experienced the following problems/side effects: bone marrow toxicity, cardiac failure, . TAXOTERE dosage: 42.5 MG. During the same period patient was treated with CISPLATIN, GEMZAR, MELOXICAM, PREGABALIN, LEVODROPROPIZINE, ASPIRIN. Patient was hospitalized. Patient recovered.

Nabucox Side Effects Report #5647023-2
Consumer or non-health professional from FRANCE reported NABUCOX problem on Feb 25, 2008. Male patient, 57 years of age, was treated with NABUCOX. After drug was administered, patient experienced the following problems/side effects: anaemia, bone marrow toxicity, cardiac arrest, cytolytic hepatitis, haematoma, histiocytosis haematophagic, inflammation, lung disorder, pain, . NABUCOX dosage: unknown. During the same period patient was treated with PROFENID, ACUPAN, MIOREL, NUROFEN, ACETAMINOPHEN, ZALDIAR, METHOCARBAMOL, EFFERALGAN CODEINE. Patient was hospitalized. Patient died on 09/09/2007.

Exjade Side Effects Report #5616690-1
EXJADE problem was reported by a Physician from FRANCE on Jan 30, 2008. Female patient, 81 years of age, weighting 103.6 lb, was diagnosed with haemochromatosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: anaemia, bone marrow toxicity, condition aggravated, haemoglobin decreased, neutrophil count decreased, pancytopenia, platelet count decreased, white blood cell count decreased, . EXJADE dosage: unknown. During the same period patient was treated with DANATROL, NITRODERM, MEDIATENSYL, LEXOMIL, LAROXYL. Patient recovered.

Exjade Side Effects Report #5535168-7
Physician from FRANCE reported EXJADE problem on Nov 28, 2007. Female patient, 81 years of age, weighting 103.6 lb, was diagnosed with haemochromatosis and was treated with EXJADE. After drug was administered, patient experienced the following problems/side effects: anaemia, bone marrow toxicity, condition aggravated, haemoglobin decreased, neutrophil count decreased, pancytopenia, platelet count decreased, white blood cell count decreased, . EXJADE dosage: unknown. During the same period patient was treated with DANATROL, NITRODERM, MEDIATENSYL, LEXOMIL, LAROXYL. Patient recovered.

Etoposide Side Effects Report #5448256-0
ETOPOSIDE problem was reported by a Pharmacist from IRELAND on Sept 04, 2007. Male patient, 40 years of age, was diagnosed with teratoma, renal transplant and was treated with ETOPOSIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, bone marrow toxicity, metastases to lung, neutropenia, neutropenic sepsis, renal impairment, teratoma, . ETOPOSIDE dosage: 240 MG/D. During the same period patient was treated with SANDIMMUNE, CARBOPLATIN. Patient was hospitalized. Patient recovered.

Velcade Side Effects Report #5441601-1
Physician from RUSSIAN FEDERATION reported VELCADE problem on Aug 23, 2007. Female patient, 70 years of age, weighting 154.3 lb, was diagnosed with multiple myeloma and was treated with VELCADE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, bone marrow toxicity, . VELCADE dosage: 1.70 MG, INTRAVENOUS. During the same period patient was treated with ETAMSILATE, RECORMON. Patient was hospitalized. Patient recovered.

Novatrex Side Effects Report #5399400-5
NOVATREX problem was reported by a Health Professional from FRANCE on July 23, 2007. Female patient, 68 years of age, weighting 134.5 lb, was diagnosed with rheumatoid arthritis, lung infection and was treated with NOVATREX. After drug was administered, patient experienced the following problems/side effects: asthenia, bone marrow toxicity, condition aggravated, dislocation of joint prosthesis, lung infection, pancytopenia, renal failure chronic, . NOVATREX dosage: 7.5 MG MONTHLY. During the same period patient was treated with ROCEPHIN, BREXIN, TAVANIC, KETEK, TAREG, SYMBICORT, BRONCHODUAL, ALPRAZOLAM. Patient was hospitalized. Patient recovered.

Novatrex Side Effects Report #5399400-5
Health Professional from FRANCE reported NOVATREX problem on July 23, 2007. Female patient, 68 years of age, weighting 134.5 lb, was diagnosed with rheumatoid arthritis, lung infection and was treated with NOVATREX. After drug was administered, patient experienced the following problems/side effects: asthenia, bone marrow toxicity, condition aggravated, dislocation of joint prosthesis, lung infection, pancytopenia, renal failure chronic, . NOVATREX dosage: 7.5 MG MONTHLY. During the same period patient was treated with ROCEPHIN, BREXIN, TAVANIC, KETEK, TAREG, SYMBICORT, BRONCHODUAL, ALPRAZOLAM. Patient was hospitalized. Patient recovered.

Thyrogen Side Effects Report #5796372-6
THYROGEN problem was reported by a Physician from UNITED STATES on June 16, 2008. Female patient, 67 years of age, weighting 207.2 lb, was treated with THYROGEN. After drug was administered, patient experienced the following problems/side effects: aptyalism, bone marrow toxicity, dehydration, diarrhoea, dry mouth, ecchymosis, epistaxis, fall, iodine uptake increased, . THYROGEN dosage: 0.9 MG, QD, INTRAMUSCULAR. During the same period patient was treated with ALLOPURINOL, ATENOLOL, DIOVAN, JANUVIA, DEMADEX, ASPIRIN, FORTAMET, LIPITOR. Patient recovered.

Cyclophosphamide Side Effects Report #5724613-X
Consumer or non-health professional from UNITED KINGDOM reported CYCLOPHOSPHAMIDE problem on Apr 17, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with CYCLOPHOSPHAMIDE. After drug was administered, patient experienced the following problems/side effects: acute respiratory distress syndrome, bone marrow toxicity, cystitis haemorrhagic, granulocytosis, herpes zoster, hypersensitivity, intestinal infarction, intestinal obstruction, neutropenia, . CYCLOPHOSPHAMIDE dosage: unknown. During the same period patient was treated with AZATHIOPRINE, RITUXIMAB, PREDNISOLONE, FOLIC ACID, AMLODIPINE, CALCICHEW D, CLARITIN, HYDROXYCHLOROQUINE SULPHATE. Patient died on 07/10/2006.

Methotrexate Side Effects Report #5374155-9
METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on June 19, 2007. Female patient, 75 years of age, was diagnosed with arthropathy, rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, bone marrow toxicity, glossitis, odynophagia, oral mucosal petechiae, pancytopenia, pneumonia, sepsis, . METHOTREXATE dosage: 15 MG WEEKLY;. During the same period patient was treated with AMINOGLYCOSIDE. Patient died.

Stavudine Side Effects Report #5288348-2
Health Professional from ITALY reported STAVUDINE problem on Mar 28, 2007. Female patient, 38 years of age, was treated with STAVUDINE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, bone marrow toxicity, hepatic failure, hepatotoxicity, platelet count decreased, renal failure, stevens-johnson syndrome, . STAVUDINE dosage: unknown. During the same period patient was treated with LAMIVUDINE, LOPINAVIR, RITONAVIR, FLUCONAZOLE, ATOVAQUONE. Patient recovered.

Etoposide Side Effects Report #5304163-5
ETOPOSIDE problem was reported by a Pharmacist from IRELAND on Apr 12, 2007. Male patient, 40 years of age, was diagnosed with teratoma, renal transplant and was treated with ETOPOSIDE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, bone marrow toxicity, metastases to lung, neutropenic sepsis, renal impairment, teratoma, . ETOPOSIDE dosage: 120MG/M2. During the same period patient was treated with SANDIMMUNE, CARBOPLATIN, ALLOPURINOL, COLCHICINE, PREDNISOLONE, NIFEDIPINE, OMEPRAZOLE, ATORVASTATIN CALCIUM. Patient recovered.

Taxotere Side Effects Report #5262360-1
Consumer or non-health professional from ITALY reported TAXOTERE problem on Feb 27, 2007. Female patient, 62 years of age, weighting 138.9 lb, was diagnosed with non-small cell lung cancer and was treated with TAXOTERE. After drug was administered, patient experienced the following problems/side effects: anaemia, bone marrow toxicity, cardiac failure, leukopenia, neutropenia, oedema peripheral, petechiae, . TAXOTERE dosage: 42.5 MG. During the same period patient was treated with CISPLATIN, GEMZAR, MELOXICAM, PREGABALIN, LEVODROPROPIZINE, ASPIRIN. Patient was hospitalized. Patient recovered.

Prograf Side Effects Report #5671991-6
PROGRAF problem was reported by a Physician from GERMANY on Feb 27, 2008. Male patient, 69 years of age, weighting 217.2 lb, was diagnosed with renal transplant, nephrogenic anaemia and was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: anisocytosis, blood creatine increased, bone marrow toxicity, epstein-barr virus test positive, haemoglobin decreased, mean cell volume increased, monocyte count increased, neutrophil count increased, red blood cell count decreased, . PROGRAF dosage: unknown. During the same period patient was treated with NEORECORMON, MYCOPHENOLATE MOFETIL, AZATHIOPRINE, ARANESP. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5677627-2
Physician from UNITED KINGDOM reported TEMOZOLOMIDE problem on Mar 06, 2008. Male patient, 40 years of age, weighting 181.7 lb, was diagnosed with metastatic malignant melanoma and was treated with TEMOZOLOMIDE. After drug was administered, patient experienced the following problems/side effects: blood bilirubin increased, blood lactate dehydrogenase increased, bone marrow toxicity, dehydration, dizziness, haemolytic anaemia, nausea, overdose, treatment noncompliance, . TEMOZOLOMIDE dosage: 320 MG. During the same period patient was treated with DOMPERIDONE, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Azathioprine Side Effects Report #5727145-8
AZATHIOPRINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 17, 2008. Female patient, 45 years of age, was diagnosed with systemic lupus erythematosus and was treated with AZATHIOPRINE. After drug was administered, patient experienced the following problems/side effects: ataxia, balance disorder, bone marrow toxicity, cerebellar syndrome, cystitis haemorrhagic, dysarthria, dysphagia, dysphasia, herpes zoster, . AZATHIOPRINE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, PREDNISOLONE, RITIUXIMAB, CORTICOSTEROIDS, LEVOTHYROXINE, PROBENECID, NUVELLE. Patient died.

Zevalin Side Effects Report #5262005-0
Health Professional from GERMANY reported ZEVALIN problem on Feb 20, 2007. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with ZEVALIN. After drug was administered, patient experienced the following problems/side effects: blood blister, bone marrow failure, bone marrow toxicity, macrocytosis, mucosal haemorrhage, neutropenia, oral mucosal blistering, red blood cell count decreased, thrombocytopenia, . ZEVALIN dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

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