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Ibuprofen Side Effects Report #5671047-2
Health Professional from UNITED KINGDOM reported IBUPROFEN problem on Mar 13, 2008. Male patient, 22 years of age, weighting 110.2 lb, was diagnosed with muscle injury and was treated with IBUPROFEN. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, hyponatraemic encephalopathy, subarachnoid haemorrhage, . IBUPROFEN dosage: unknown. Patient died on 04/22/2007.

Ibuprofen Side Effects Report #5671934-5
IBUPROFEN problem was reported by a Health Professional from UNITED KINGDOM on Mar 14, 2008. Male patient, 22 years of age, weighting 110.2 lb, was diagnosed with muscle injury and was treated with IBUPROFEN. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, hyponatraemic encephalopathy, . IBUPROFEN dosage: unknown. Patient died on 04/22/2007.

Revlimid Side Effects Report #5680951-0
Physician from UNITED STATES reported REVLIMID problem on Mar 19, 2008. Female patient, 67 years of age, was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain mass, cerebellar haemorrhage, malignant neoplasm progression, myelodysplastic syndrome, nervous system disorder, pancytopenia, . REVLIMID dosage: 5 MG, 1 IN 1 D, ORAL. Patient died.

Bisoprolol Side Effects Report #5682241-9
BISOPROLOL FUMARATE problem was reported by a Consumer or non-health professional from FRANCE on Mar 17, 2008. Female patient, 87 years of age, was treated with BISOPROLOL FUMARATE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, coma, fall, haematoma, humerus fracture, international normalised ratio increased, musculoskeletal disorder, pallor, . BISOPROLOL FUMARATE dosage: unknown. During the same period patient was treated with PREVISCAN, ALLOPURINOL, PRAVASTATIN, TOPALGIC, ZOLOFT, PREDNISOLONE, FUROSEMIDE, FORLAX. Patient was hospitalized. Patient died.


Arixtra Side Effects Report #5612621-9
Physician from FRANCE reported ARIXTRA problem on Jan 25, 2008. Female patient, 74 years of age, weighting 165.3 lb, was diagnosed with deep vein thrombosis and was treated with ARIXTRA. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebrovascular accident, . ARIXTRA dosage: 7.5MG PER DAY. During the same period patient was treated with PREVISCAN, VASTAREL, ATACAND, LODALES, ART, MOPRAL, ACETAMINOPHEN. Patient was hospitalized. Patient died on 12/01/2007.

Enbrel Side Effects Report #5622824-5
ENBREL problem was reported by a Physician from UNITED STATES on Feb 08, 2008. Male patient was diagnosed with psoriasis and was treated with ENBREL. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, intracranial pressure increased, pupil fixed, respiratory arrest, . ENBREL dosage: 50 MG BIW SQ. Patient died on 01/27/2008.

Arsenic Side Effects Report #5646733-0
Consumer or non-health professional from UNITED KINGDOM reported ARSENIC TRIOXIDE problem on Feb 20, 2008. Female patient, 71 years of age, was diagnosed with acute myeloid leukaemia and was treated with ARSENIC TRIOXIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, haemoglobin decreased, hydrocephalus, platelet count abnormal, subdural haemorrhage, white blood cell count decreased, . ARSENIC TRIOXIDE dosage: unknown. During the same period patient was treated with CYTARABINE. Patient recovered.

Arixtra Side Effects Report #5600208-3
ARIXTRA problem was reported by a Pharmacist from UNITED STATES on Jan 17, 2008. Male patient, 58 years of age, weighting 192.0 lb, was diagnosed with cardiolipin antibody positive and was treated with ARIXTRA. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, respiratory failure, . ARIXTRA dosage: 7.5MG QD SQ. Patient died on 01/11/2008.

Arsenic Side Effects Report #5614444-3
Physician from UNITED KINGDOM reported ARSENIC TRIOXIDE problem on Jan 15, 2008. Female patient, 71 years of age, was diagnosed with acute myeloid leukaemia and was treated with ARSENIC TRIOXIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, haemoglobin decreased, hydrocephalus, platelet count decreased, subdural haemorrhage, white blood cell count increased, . ARSENIC TRIOXIDE dosage: unknown. During the same period patient was treated with CYTARABINE. Patient recovered.


Prednisone Side Effects Report #5578180-4
PREDNISONE problem was reported by a Physician from IRAN (ISLAMIC REPUBLIC OF) on Dec 08, 2007. Female patient, 22 years of age, was diagnosed with colitis ulcerative and was treated with PREDNISONE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, depressed level of consciousness, encephalitis herpes, . PREDNISONE dosage: unknown. During the same period patient was treated with AZATHIOPRINE, ORAPRED, AMINOSALICYLATE. Patient was hospitalized. Patient recovered.

Phenytoin Side Effects Report #5580029-0
Health Professional from UNITED KINGDOM reported PHENYTOIN problem on Dec 18, 2007. Female patient, 66 years of age, was diagnosed with convulsion prophylaxis and was treated with PHENYTOIN. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral ischaemia, haemoglobin decreased, haemorrhage intracranial, thrombocytopenia, . PHENYTOIN dosage: 300 MG; DAILY;. During the same period patient was treated with DEXAMETHASONE, AMLODIPINE, METFORMIN. Patient died.

Warfarin Side Effects Report #5580118-0
WARFARIN problem was reported by a Pharmacist from UNITED STATES on Dec 27, 2007. Female patient, 73 years of age, was diagnosed with heart valve replacement and was treated with WARFARIN. After drug was administered, patient experienced the following problems/side effects: brain herniation, coagulopathy, fall, international normalised ratio increased, loss of consciousness, subdural haematoma, . WARFARIN dosage: unknown. During the same period patient was treated with STARLIX, PROTONIX, FOSAMAX, LIPITOR, AVANDIA, CALCIUM, FISH OIL. Patient was hospitalized. Patient died on 12/11/2007.

Novoseven Side Effects Report #5512598-0
Pharmacist from UNITED STATES reported NOVOSEVEN problem on Nov 08, 2007. Male patient, 55 years of age, weighting 172.0 lb, was treated with NOVOSEVEN. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral infarction, electroencephalogram abnormal, encephalopathy, loss of consciousness, . NOVOSEVEN dosage: 4.8 MG TWICE 4 HRS APART IV. Patient died on 11/02/2007.

Actos Side Effects Report #5518303-6
ACTOS problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 14, 2007. Male patient, weighting 195.0 lb, was diagnosed with blood glucose increased and was treated with ACTOS. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain malformation, cardiac failure congestive, cardiomegaly, fall, nosocomial infection, oedema, pseudomonas infection, staphylococcal infection, . ACTOS dosage: 15 MG DAILY PO. Patient was hospitalized. Patient died on 03/05/2007.


Bactrim Side Effects Report #5518416-9
Pharmacist from UNITED STATES reported BACTRIM problem on Nov 13, 2007. Female patient, 17 years of age, weighting 110.2 lb, was diagnosed with acne and was treated with BACTRIM. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral disorder, headache, mental status changes, pyrexia, rash maculo-papular, skin disorder, . BACTRIM dosage: unknown. Patient died on 06/14/2007.

Campath Side Effects Report #5520119-1
CAMPATH problem was reported by a Health Professional from UNITED STATES on Nov 06, 2007. Male patient, 64 years of age, weighting 269.0 lb, was diagnosed with infection prophylaxis and was treated with CAMPATH. After drug was administered, patient experienced the following problems/side effects: brain herniation, convulsion, hypertension, meningitis viral, somnolence, . CAMPATH dosage: 3/10/30 MG TIWX6 WEEKS. During the same period patient was treated with FLUDARA, RITUXAN, BENADRYL, ACETAMINOPHEN, COTRIM, ACYCLOVIR, TRICOR, CYCLOBENZAPRINE. Patient was hospitalized. Patient died on 06/01/2006.

Campath Side Effects Report #5523872-6
Health Professional from UNITED STATES reported CAMPATH problem on Nov 09, 2007. Male patient, 64 years of age, weighting 269.0 lb, was diagnosed with infection prophylaxis and was treated with CAMPATH. After drug was administered, patient experienced the following problems/side effects: brain herniation, convulsion, hypertension, meningitis viral, somnolence, . CAMPATH dosage: 3/10/30 MG TIWX6 WEEKS. During the same period patient was treated with FLUDARA, RITUXAN, BENADRYL, ACETAMINOPHEN, COTRIM, ACYCLOVIR, TRICOR, CYCLOBENZAPRINE. Patient was hospitalized. Patient died on 06/01/2006.

Warfarin Side Effects Report #5533290-2
WARFARIN problem was reported by a Pharmacist from UNITED STATES on Nov 30, 2007. Male patient, 70 years of age, was treated with WARFARIN. After drug was administered, patient experienced the following problems/side effects: brain herniation, fall, loss of consciousness, subdural haematoma, . WARFARIN dosage: 15MG DAILY PO. During the same period patient was treated with LOVENOX, AMLODIPINE, COREG, SURFAK, PHOSLO, ZOLOFT, LANTUS, PROVENTIL. Patient was hospitalized. Patient died on 11/19/2007.

Dilantin Side Effects Report #5480036-2
Physician from PHILIPPINES reported DILANTIN problem on Sept 26, 2007. Male patient, 56 years of age, was diagnosed with convulsion and was treated with DILANTIN. After drug was administered, patient experienced the following problems/side effects: brain herniation, stevens-johnson syndrome, . DILANTIN dosage: unknown. During the same period patient was treated with METOPROLOL TARTRATE, NORVASC, PLAVIX. Patient died on 09/11/2007.


Dilantin Side Effects Report #5464914-6
DILANTIN problem was reported by a Physician from PHILIPPINES on Sept 11, 2007. Male patient, 56 years of age, was diagnosed with convulsion and was treated with DILANTIN. After drug was administered, patient experienced the following problems/side effects: brain herniation, stevens-johnson syndrome, . DILANTIN dosage: unknown. During the same period patient was treated with METOPROLOL SUCCINATE, NORVASC, PLAVIX. Patient died on 09/11/2007.

Irinotecan Side Effects Report #5409404-1
Consumer or non-health professional from UNITED STATES reported IRINOTECAN problem on Aug 08, 2007. Male patient, weighting 159.6 lb, was diagnosed with glioblastoma multiforme and was treated with IRINOTECAN. After drug was administered, patient experienced the following problems/side effects: brain herniation, convulsion, haemorrhage, headache, mental status changes, nervous system disorder, posturing, . IRINOTECAN dosage: 325MG/M2 DAY 1 IV. During the same period patient was treated with TEMODAR, DILANTIN KAPSEAL, DEXAMETHASONE, ATIVAN, DECADRON, PHENERGAN, MOTRIN, OXYCODONE. Patient died on 07/03/2007.

Pramipexole Side Effects Report #5411982-3
PRAMIPEXOLE DIHYDROCHLORIDE problem was reported by a Consumer or non-health professional from JAPAN on Aug 07, 2007. Female patient, weighting 83.78 lb, was diagnosed with parkinson's disease, psychiatric symptom, constipation and was treated with PRAMIPEXOLE DIHYDROCHLORIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral artery embolism, decreased appetite, fall, femur fracture, gamma-glutamyltransferase increased, hallucination, pneumonia aspiration, syncope, . PRAMIPEXOLE DIHYDROCHLORIDE dosage: unknown. During the same period patient was treated with ARICEPT, TETRAMIDE, SEROQUEL, PURSENNID, SYMMETREL, NEODOPASOL. Patient was hospitalized. Patient died on 09/16/2006.

Pramipexole Side Effects Report #5421443-3
Consumer or non-health professional from JAPAN reported PRAMIPEXOLE DIHYDROCHLORIDE problem on Aug 07, 2007. Female patient, weighting 83.78 lb, was diagnosed with parkinson's disease, psychiatric symptom, constipation and was treated with PRAMIPEXOLE DIHYDROCHLORIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral artery embolism, decreased appetite, fall, femur fracture, gamma-glutamyltransferase increased, hallucination, pneumonia aspiration, syncope, . PRAMIPEXOLE DIHYDROCHLORIDE dosage: unknown. During the same period patient was treated with ARICEPT, TETRAMIDE, SEROQUEL, PURSENNID, SYMMETREL, NEODOPASOL. Patient was hospitalized and became disabled. Patient died on 09/16/2006.

Pramipexole Side Effects Report #5422740-8
PRAMIPEXOLE DIHYDROCHLORIDE problem was reported by a Consumer or non-health professional from JAPAN on Aug 07, 2007. Female patient, weighting 83.78 lb, was diagnosed with parkinson's disease, psychiatric symptom, constipation and was treated with PRAMIPEXOLE DIHYDROCHLORIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral artery embolism, decreased appetite, fall, femur fracture, gamma-glutamyltransferase increased, hallucination, pneumonia aspiration, syncope, . PRAMIPEXOLE DIHYDROCHLORIDE dosage: unknown. During the same period patient was treated with SEROQUEL, ARICEPT, TETRAMIDE, PURSENNID, SYMMETREL, NEODOPASOL, GRAMALIL. Patient was hospitalized. Patient died on 09/16/2006.

Alteplase Side Effects Report #5424707-2
Pharmacist from UNITED STATES reported ALTEPLASE problem on Aug 22, 2007. Male patient, 80 years of age, weighting 160.1 lb, was diagnosed with ischaemic stroke and was treated with ALTEPLASE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, subarachnoid haemorrhage, . ALTEPLASE dosage: 7.2MG ONCE IV. Patient died on 06/11/2007.

Pramipexole Side Effects Report #5425420-8
PRAMIPEXOLE DIHYDROCHLORIDE problem was reported by a Consumer or non-health professional from JAPAN on Aug 07, 2007. Female patient, weighting 83.78 lb, was diagnosed with parkinson's disease, psychiatric symptom, constipation and was treated with PRAMIPEXOLE DIHYDROCHLORIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral artery embolism, decreased appetite, fall, femur fracture, gamma-glutamyltransferase increased, hallucination, pneumonia aspiration, syncope, . PRAMIPEXOLE DIHYDROCHLORIDE dosage: unknown. During the same period patient was treated with SEROQUEL, ARICEPT, TETRAMIDE, PURSENNID, SYMMETREL, NEODOPASOL, GRAMALIL. Patient was hospitalized. Patient died on 09/16/2006.

Irinotecan Side Effects Report #5427033-0
Consumer or non-health professional from UNITED STATES reported IRINOTECAN problem on Aug 24, 2007. Male patient, weighting 185.2 lb, was diagnosed with glioblastoma multiforme and was treated with IRINOTECAN. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, depressed level of consciousness, diarrhoea, glioblastoma multiforme, nausea, neoplasm progression, somnolence, . IRINOTECAN dosage: 325MG/M2 DAY 1,8,22,29 IV. During the same period patient was treated with TEMODAR, DEXAMETHASONE, ZANTAC, PHENOBARBITAL. Patient was hospitalized. Patient recovered.

Vincristine Side Effects Report #5427320-6
VINCRISTINE problem was reported by a Consumer or non-health professional from FRANCE on Aug 13, 2007. Male patient, 61 years of age, was treated with VINCRISTINE. After drug was administered, patient experienced the following problems/side effects: brain herniation, endocarditis staphylococcal, ischaemic stroke, lung abscess, sepsis, septic embolus, . VINCRISTINE dosage: unknown. During the same period patient was treated with DEXAMETHASONE, DOXORUBICIN. Patient died on 06/29/2007.

Irinotecan Side Effects Report #5427509-6
Consumer or non-health professional from UNITED STATES reported IRINOTECAN problem on Aug 24, 2007. Male patient, weighting 159.6 lb, was diagnosed with glioblastoma multiforme and was treated with IRINOTECAN. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, convulsion, headache, incontinence, mental status changes, neoplasm progression, . IRINOTECAN dosage: 325MG/M2 DAY 1 IV. During the same period patient was treated with TEMODAR, DILANTIN, DEXAMETHASONE, ATIVAN. Patient died on 07/03/2007.

Pramipexole Side Effects Report #5428324-X
PRAMIPEXOLE DIHYDROCHLORIDE problem was reported by a Consumer or non-health professional from JAPAN on Aug 07, 2007. Female patient, weighting 83.78 lb, was diagnosed with parkinson's disease, psychiatric symptom, constipation and was treated with PRAMIPEXOLE DIHYDROCHLORIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral artery embolism, decreased appetite, fall, femur fracture, gamma-glutamyltransferase increased, hallucination, pneumonia aspiration, syncope, . PRAMIPEXOLE DIHYDROCHLORIDE dosage: unknown. During the same period patient was treated with SEROQUEL, ARICEPT, TETRAMIDE, PURSENNID, SYMMETREL, NEODOPASOL, GRAMALIL. Patient was hospitalized. Patient died on 09/16/2006.

Enalapril Side Effects Report #5429189-2
Consumer or non-health professional from UNITED KINGDOM reported ENALAPRIL MALEATE problem on Aug 02, 2007. Male patient, 32 years of age, was diagnosed with hypertension and was treated with ENALAPRIL MALEATE. After drug was administered, patient experienced the following problems/side effects: brain herniation, bronchopneumonia, cerebral infarction, hypertension, left ventricular hypertrophy, leukoencephalomyelitis, vasculitis, . ENALAPRIL MALEATE dosage: unknown. During the same period patient was treated with AMLODIPINE BESYLATE, INSULIN. Patient died.

Amantadine Side Effects Report #5377693-8
AMANTADINE problem was reported by a Consumer or non-health professional from on July 02, 2007. Female patient, child 10 years of age, was diagnosed with rabies and was treated with AMANTADINE. After drug was administered, patient experienced the following problems/side effects: brain herniation, diabetes insipidus, inappropriate antidiuretic hormone secretion, intracranial pressure increased, intracranial venous sinus thrombosis, pancreatitis, . AMANTADINE dosage: unknown. During the same period patient was treated with MIDAZOLAM, ASCORBIC ACID, PHENOBARBITAL, KETAMINE, RIBAVIRIN, COENZYME Q, TETRAHYDROBIOPTERIN. Patient died on 11/02/2006.

Amantadine Side Effects Report #5377693-8
Consumer or non-health professional from reported AMANTADINE problem on July 02, 2007. Female patient, child 10 years of age, was diagnosed with rabies and was treated with AMANTADINE. After drug was administered, patient experienced the following problems/side effects: brain herniation, diabetes insipidus, inappropriate antidiuretic hormone secretion, intracranial pressure increased, intracranial venous sinus thrombosis, pancreatitis, . AMANTADINE dosage: unknown. During the same period patient was treated with MIDAZOLAM, ASCORBIC ACID, PHENOBARBITAL, KETAMINE, RIBAVIRIN, COENZYME Q, TETRAHYDROBIOPTERIN. Patient died on 11/02/2006.

Tasigna Side Effects Report #5774991-0
TASIGNA problem was reported by a Physician from TAIWAN, PROVINCE OF CHINA on June 13, 2008. Female patient, weighting 131.2 lb, was diagnosed with chronic myeloid leukaemia and was treated with TASIGNA. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebrovascular accident, haemorrhage intracranial, headache, hypertension, loss of consciousness, thrombocytopenia, . TASIGNA dosage: 800MG DAILY. Patient was hospitalized. Patient died on 05/26/2008.

Arixtra Side Effects Report #5731850-7
Consumer or non-health professional from FRANCE reported ARIXTRA problem on Apr 28, 2008. Male patient, 83 years of age, was diagnosed with phlebitis and was treated with ARIXTRA. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haematoma, cerebral haemorrhage, . ARIXTRA dosage: unknown. During the same period patient was treated with PLAVIX, SERTRALINE, VITAMIN E, GINKGO BILOBA. Patient was hospitalized. Patient died on 02/07/2008.

Arixtra Side Effects Report #5747818-0
ARIXTRA problem was reported by a Consumer or non-health professional from FRANCE on May 15, 2008. Male patient, 83 years of age, weighting 198.4 lb, was diagnosed with phlebitis and was treated with ARIXTRA. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haematoma, cerebral haemorrhage, . ARIXTRA dosage: unknown. During the same period patient was treated with PLAVIX, SERTRALINE, VITAMIN E, GINKGO BILOBA. Patient was hospitalized. Patient died on 02/07/2008.

Campath Side Effects Report #5749033-3
Consumer or non-health professional from UNITED STATES reported CAMPATH problem on May 20, 2008. Male patient, 63 years of age, weighting 269.0 lb, was diagnosed with chronic lymphocytic leukaemia, infection prophylaxis and was treated with CAMPATH. After drug was administered, patient experienced the following problems/side effects: brain herniation, convulsion, hypertension, meningitis viral, somnolence, . CAMPATH dosage: unknown. During the same period patient was treated with FLUDARA, RITUXAN, BENADRYL, ACETAMINOPHEN, COTRIM, ACYCLOVIR, TRICOR, CYCLOBENZAPRINE. Patient was hospitalized. Patient died on 06/16/2006.

Remicade Side Effects Report #5697490-3
REMICADE problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 28, 2008. Female patient, weighting 120.0 lb, was diagnosed with colitis ulcerative, insomnia, vomiting and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, thrombosis, . REMICADE dosage: unknown. During the same period patient was treated with ZOLPIDEM, LORAZEPAM, PREDNISONE, ASACOL, PENTASA, BELLADONNA, METOCLOPRAMIDE. Patient was hospitalized. Patient died on 07/26/2007.

Arsenic Side Effects Report #5700267-3
Health Professional from UNITED STATES reported ARSENIC TRIOXIDE problem on Mar 25, 2008. Female patient, 27 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with ARSENIC TRIOXIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, cerebral infarction, cerebrovascular disorder, confusional state, convulsion, disease complication, disseminated intravascular coagulation, dysarthria, . ARSENIC TRIOXIDE dosage: 0.15 MG/KG QD INTRAVENOUS. Patient was hospitalized. Patient died.

Aprovel Side Effects Report #5717522-3
APROVEL problem was reported by a Health Professional from FRANCE on Apr 22, 2008. Female patient, 80 years of age, was treated with APROVEL. After drug was administered, patient experienced the following problems/side effects: brain herniation, coma, fall, hypercreatininaemia, malaise, pneumocephalus, skull fractured base, subdural haematoma, . APROVEL dosage: unknown. During the same period patient was treated with SINTROM, LASILIX RETARD, CATAPRES, CHRONADALATE, HYDREA, FENOFIBRATE. Patient was hospitalized. Patient died on 10/17/2007.

Humira Side Effects Report #5342719-4
Physician from DENMARK reported HUMIRA problem on May 24, 2007. Male patient, weighting 187.4 lb, was diagnosed with rheumatoid arthritis, hypertension and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: brain herniation, cough, intracranial pressure increased, mass, metastases to central nervous system, metastases to lymph nodes, non-small cell lung cancer, . HUMIRA dosage: unknown. During the same period patient was treated with INFLIXIMAB, KINERET, RITUXIMAB, METHOTREXATE, FOLIC ACID, ACE INHIBITOR NOS. Patient was hospitalized. Patient died on 04/06/2007.

Campath Side Effects Report #5367778-4
CAMPATH problem was reported by a Physician from UNITED STATES on June 11, 2007. Female patient was diagnosed with infection prophylaxis and was treated with CAMPATH. After drug was administered, patient experienced the following problems/side effects: brain herniation, encephalitic infection, meningitis viral, . CAMPATH dosage: 3/10/30 MG TIWX6 WEEKS. During the same period patient was treated with FLUDARA, RITUXAN, BENADRYL, ACETAMINOPHEN, COTRIM. Patient died on 06/01/2006.

Landsen Side Effects Report #5320343-7
Physician from JAPAN reported LANDSEN problem on Apr 27, 2007. Male patient, 32 years of age, weighting 135.6 lb, was diagnosed with prophylaxis, sedation, schizophrenia and was treated with LANDSEN. After drug was administered, patient experienced the following problems/side effects: brain herniation, cardiac arrest, clonic convulsion, eczema, neuroleptic malignant syndrome, . LANDSEN dosage: 2 MG, DAILY (1/D). During the same period patient was treated with AKINETON, CERCINE, HALOPERIDOL. Patient was hospitalized and became disabled. Patient recovered.

Cyclophosphamide Side Effects Report #5323523-X
CYCLOPHOSPHAMIDE problem was reported by a Consumer or non-health professional from UNITED STATES on May 10, 2007. Female patient, weighting 132.1 lb, was treated with CYCLOPHOSPHAMIDE. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, hypotension, subarachnoid haemorrhage, tachycardia, . CYCLOPHOSPHAMIDE dosage: 2052 MG. During the same period patient was treated with DAUNORUBICIN, VINCRISTINE SULPHATE, ALLOPURINOL. Patient was hospitalized. Patient died on 05/06/2007.

Ambisome Side Effects Report #5324523-6
Health Professional from JAPAN reported AMBISOME problem on Apr 26, 2007. Female patient, 35 years of age, was diagnosed with cryptococcosis, hiv infection and was treated with AMBISOME. After drug was administered, patient experienced the following problems/side effects: brain herniation, condition aggravated, cryptococcosis, disease recurrence, gastrointestinal disorder, hypertension, immune reconstitution syndrome, . AMBISOME dosage: unknown. During the same period patient was treated with TRUVADA, ANCOTIL, EFAVIRENZ, SULFAMETHOXAZOLE, ZITHROMAC, MYCOPHENOLATE MOFETIL, PEPCID. Patient was hospitalized. Patient recovered.

Arixtra Side Effects Report #5337251-8
ARIXTRA problem was reported by a Physician from FRANCE on May 18, 2007. Female patient, 87 years of age, weighting 88.18 lb, was diagnosed with atrial fibrillation, myocardial ischaemia, arterial disorder and was treated with ARIXTRA. After drug was administered, patient experienced the following problems/side effects: brain herniation, coma, hypotonia, malaise, mydriasis, off label use, subdural haematoma, . ARIXTRA dosage: unknown. During the same period patient was treated with CORDARONE, TRIATEC, LASIX, VADILEX, KARDEGIC, CARDENSIEL. Patient was hospitalized. Patient died on 02/28/2007.

Orthoclone Side Effects Report #5228434-6
Physician from JAPAN reported ORTHOCLONE OKT problem on Jan 26, 2007. Male patient, 56 years of age, was diagnosed with transplant rejection, prophylaxis against transplant rejection, liver transplant and was treated with ORTHOCLONE OKT. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, cardio-respiratory arrest, cardiogenic shock, encephalopathy, haemolysis, renal failure acute, ventricular tachycardia, . ORTHOCLONE OKT dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, POLARAMINE, IMMUNE GLOBULIN INTRAVENOUS, VOLTAREN, CHLORTHALIDONE, CHLORPHENIRAMINE MALEATE, TACROLIMUS. Patient was hospitalized. Patient died on 01/26/2007.

Orthoclone Side Effects Report #5236862-8
ORTHOCLONE OKT problem was reported by a Physician from JAPAN on Feb 05, 2007. Male patient, 56 years of age, was diagnosed with transplant rejection, prophylaxis against transplant rejection, liver transplant and was treated with ORTHOCLONE OKT. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, cardio-respiratory arrest, cardiogenic shock, encephalopathy, haemolysis, multi-organ failure, pneumonia, renal failure acute, . ORTHOCLONE OKT dosage: unknown. During the same period patient was treated with METHYLPREDNISOLONE, POLARAMINE, IMMUNE GLOBULIN INTRAVENOUS, VOLTAREN, CHLORTHALIDONE, CHLORPHENIRAMINE MALEATE, TACROLIMUS. Patient was hospitalized. Patient died on 01/26/2007.

Gleevec Side Effects Report #5295683-0
Health Professional from UNITED STATES reported GLEEVEC problem on Apr 10, 2007. Male patient, weighting 111.1 lb, was diagnosed with astrocytoma and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: brain herniation, brain oedema, convulsion, headache, loss of consciousness, malignant neoplasm progression, respiratory arrest, . GLEEVEC dosage: 500 MG BID PO. During the same period patient was treated with HYDROXYUREA, CYMBALTA, DECADRON, PEPCIS, KEPPRA, DILANTIN, TRILEPTAL, POTASSIUM CHLORIDE. Patient was hospitalized. Patient died on 04/03/2007.

Enoxaparin Side Effects Report #5299340-6
ENOXAPARIN problem was reported by a Pharmacist from UNITED STATES on Apr 11, 2007. Female patient, 76 years of age, weighting 175.0 lb, was diagnosed with cerebrovascular accident, transient ischaemic attack, atrial fibrillation and was treated with ENOXAPARIN. After drug was administered, patient experienced the following problems/side effects: brain herniation, cerebral haemorrhage, depressed level of consciousness, haemorrhage intracranial, vomiting, . ENOXAPARIN dosage: 80MG BID SQ. During the same period patient was treated with WARFARIN, ASPIRIN, AGGRENOX, CYMBALTA, COZAAR, SENOKOT, VESICAR. Patient was hospitalized. Patient died on 12/18/2006.

Activase Side Effects Report #5304468-8
Physician from JAPAN reported ACTIVASE problem on Apr 18, 2007. Male patient, 65 years of age, was diagnosed with cerebral artery embolism and was treated with ACTIVASE. After drug was administered, patient experienced the following problems/side effects: brain herniation, . ACTIVASE dosage: 30.7 ML, SINGLE. During the same period patient was treated with ASPIRIN. Patient was hospitalized. Patient recovered.