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Fabrazyme Side Effects Report #5405598-2
Consumer or non-health professional from UNITED STATES reported FABRAZYME problem on July 23, 2007. Male patient, 49 years of age, weighting 120.6 lb, was diagnosed with fabry's disease and was treated with FABRAZYME. After drug was administered, patient experienced the following problems/side effects: finger amputation, gangrene, impaired healing, localised infection, osteomyelitis, skin laceration, toe amputation, . FABRAZYME dosage: 1 MG/KG, Q2WKS; IV. During the same period patient was treated with ASPIRIN, LASIX, TOPROL XL, VERAPAMIL EXTENDED, AMIODARONE, COZAAR, PRAVACHOL, MEDROL. Patient was hospitalized. Patient recovered.

Humira Side Effects Report #5737182-5
HUMIRA problem was reported by a Consumer or non-health professional from UNITED STATES on May 13, 2008. Female patient, 39 years of age, weighting 215.0 lb, was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: finger amputation, gangrene, nasopharyngitis, pain in extremity, sepsis, skin ulcer, streptococcal infection, . HUMIRA dosage: unknown. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient recovered.

Thalomid Side Effects Report #5373146-1
Physician from UNITED STATES reported THALOMID problem on June 18, 2007. Female patient, 68 years of age, was diagnosed with myelofibrosis and was treated with THALOMID. After drug was administered, patient experienced the following problems/side effects: finger amputation, gangrene, nail bed infection, pain in extremity, . THALOMID dosage: 50-100 MG, DAILY, ORAL. During the same period patient was treated with XANAX, CIPRO, PREDNISONE. Patient was hospitalized. Patient recovered.

Thalomid Side Effects Report #5373985-7
THALOMID problem was reported by a Physician from UNITED STATES on June 19, 2007. Male patient, 55 years of age, was diagnosed with multiple myeloma and was treated with THALOMID. After drug was administered, patient experienced the following problems/side effects: finger amputation, osteomyelitis, . THALOMID dosage: 200 MG, 1 IN 1D, ORAL. During the same period patient was treated with DECADRON, ZOCOR, ZYPREXA, LITHIUM CARBONATE, CACLIUM WITH D. Patient recovered.


Rebif Side Effects Report #5318547-2
Physician from UNITED STATES reported REBIF problem on Apr 19, 2007. Female patient, 44 years of age, weighting 225.0 lb, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: finger amputation, necrosis, raynaud's phenomenon, skin ulcer, splinter haemorrhages, . REBIF dosage: unknown. During the same period patient was treated with AMANTADINE, ASPIRIN, DYAZIDE, NORVASC, NEXIUM, NITRO CREAM, POTASSIUM. Patient recovered.

Fabrazyme Side Effects Report #5613988-8
FABRAZYME problem was reported by a Physician from UNITED STATES on Jan 22, 2008. Male patient, 50 years of age, weighting 120.6 lb, was diagnosed with fabry's disease and was treated with FABRAZYME. After drug was administered, patient experienced the following problems/side effects: cardiac arrest, finger amputation, pneumonia, sepsis, . FABRAZYME dosage: 1 MG/KG, Q2W, INTRAVENOUS. During the same period patient was treated with COZAAR, PRAVACHOL, MEDROL, RENAL CAPS, COMBIVENT, ADVAIR, COUMADIN, IMURAN. Patient died on 01/04/2008.

Aranesp Side Effects Report #5562772-2
Physician from AUSTRALIA reported ARANESP problem on Dec 05, 2007. Male patient, weighting 121.3 lb, was treated with ARANESP. After drug was administered, patient experienced the following problems/side effects: calciphylaxis, finger amputation, haemoglobin increased, ischaemia, . ARANESP dosage: unknown. Patient was hospitalized. Patient recovered.

Nitroglycerin Side Effects Report #5503525-0
NITROGLYCERIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 11, 2007. Male patient, 34 years of age, was diagnosed with peripheral vascular disorder, pain in extremity and was treated with NITROGLYCERIN. After drug was administered, patient experienced the following problems/side effects: cyanosis, finger amputation, gangrene, no therapeutic response, peripheral arterial occlusive disease, peripheral ischaemia, peripheral vascular disorder, . NITROGLYCERIN dosage: unknown. During the same period patient was treated with NIFEDIPINE, HYDROXYUREA, ASPIRIN. Patient was hospitalized and became disabled. Patient recovered.

Humira Side Effects Report #5767782-8
Consumer or non-health professional from BRAZIL reported HUMIRA problem on June 04, 2008. Female patient, weighting 114.6 lb, was diagnosed with rheumatoid arthritis, cardiovascular disorder, blood pressure management, anaemia and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: cardiovascular disorder, finger amputation, localised infection, urinary tract infection, . HUMIRA dosage: unknown. During the same period patient was treated with LEFLUNOMIDE, PENTOXIFYLLINE, LOSARTAN POTASSIUM, ERITROPOYETINA. Patient was hospitalized. Patient recovered.


Erbitux Side Effects Report #5719437-3
ERBITUX problem was reported by a Consumer or non-health professional from GERMANY on Apr 21, 2008. Female patient, 69 years of age, was diagnosed with colorectal cancer metastatic and was treated with ERBITUX. After drug was administered, patient experienced the following problems/side effects: disease progression, finger amputation, inflammation, metastases to bone, osteomyelitis, . ERBITUX dosage: unknown. Patient was hospitalized. Patient recovered.

Remicade Side Effects Report #5283387-X
Physician from UNITED STATES reported REMICADE problem on Mar 19, 2007. Female patient, weighting 128.0 lb, was diagnosed with rheumatoid arthritis and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: dry gangrene, finger amputation, leg amputation, legionella infection, lung infection, renal failure acute, septic shock, staphylococcal skin infection, . REMICADE dosage: unknown. During the same period patient was treated with ARAVA, PREDNISONE. Patient was hospitalized and became disabled. Patient recovered.

Stilnox Side Effects Report #5289831-6
STILNOX problem was reported by a Consumer or non-health professional from AUSTRALIA on Mar 28, 2007. Male patient was treated with STILNOX. After drug was administered, patient experienced the following problems/side effects: amnesia, finger amputation, . STILNOX dosage: unknown. Patient recovered.

Ethyol Side Effects Report #5298474-X
Health Professional from UNITED STATES reported ETHYOL problem on Mar 27, 2007. Male patient, 53 years of age, weighting 180.0 lb, was diagnosed with neoplasm malignant and was treated with ETHYOL. After drug was administered, patient experienced the following problems/side effects: erythema, finger amputation, neoplasm recurrence, oedema peripheral, pain in extremity, pyrexia, secretion discharge, skin discolouration, skin ulcer, . ETHYOL dosage: 500 MG, 5 IN 5 D, SUBCUTANEOUS. During the same period patient was treated with ERBITUX, CISPLATIN, TAXOTERE, PROTONIX, DECADRON. Patient was hospitalized. Patient recovered.

Remicade Side Effects Report #5254880-0
REMICADE problem was reported by a Physician from UNITED STATES on Feb 26, 2007. Female patient, 42 years of age, was diagnosed with rheumatoid arthritis and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: dry gangrene, finger amputation, leg amputation, legionella infection, renal failure acute, septic shock, . REMICADE dosage: unknown. During the same period patient was treated with PREDNISONE. Patient was hospitalized. Patient recovered.


Heparin Side Effects Report #5657489-X
Health Professional from UNITED KINGDOM reported HEPARIN problem on Feb 27, 2008. Male patient, 43 years of age, was diagnosed with arterial thrombosis limb and was treated with HEPARIN. After drug was administered, patient experienced the following problems/side effects: extremity necrosis, finger amputation, . HEPARIN dosage: unknown. During the same period patient was treated with ACTIVASE. Patient was hospitalized. Patient recovered.

Nifedipine Side Effects Report #5494146-7
NIFEDIPINE problem was reported by a Physician from UNITED STATES on Oct 11, 2007. Male patient, 34 years of age, was diagnosed with pain in extremity and was treated with NIFEDIPINE. After drug was administered, patient experienced the following problems/side effects: cyanosis, finger amputation, gangrene, pain in extremity, peripheral ischaemia, peripheral vascular disorder, platelet count abnormal, skin discolouration, . NIFEDIPINE dosage: unknown. During the same period patient was treated with ASPIRIN, NITROGLYCERIN, HYDROXYUREA. Patient was hospitalized and became disabled. Patient recovered.

Promethazine Side Effects Report #5389131-X
Pharmacist from UNITED STATES reported PROMETHAZINE problem on July 13, 2007. Male patient, 39 years of age, weighting 170.0 lb, was diagnosed with nausea, vomiting and was treated with PROMETHAZINE. After drug was administered, patient experienced the following problems/side effects: cyanosis, dry gangrene, finger amputation, infusion related reaction, neuralgia, no therapeutic response, pain, thrombosis, . PROMETHAZINE dosage: unknown. Patient recovered.

Promethazine Side Effects Report #5389131-X
PROMETHAZINE problem was reported by a Pharmacist from UNITED STATES on July 13, 2007. Male patient, 39 years of age, weighting 170.0 lb, was diagnosed with nausea, vomiting and was treated with PROMETHAZINE. After drug was administered, patient experienced the following problems/side effects: cyanosis, dry gangrene, finger amputation, infusion related reaction, neuralgia, no therapeutic response, pain, thrombosis, . PROMETHAZINE dosage: unknown. Patient recovered.

Avonex Side Effects Report #5367985-0
Consumer or non-health professional from UNITED KINGDOM reported AVONEX problem on June 11, 2007. Male patient, 36 years of age, weighting 167.6 lb, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: accident, fatigue, finger amputation, influenza like illness, limb injury, . AVONEX dosage: unknown. During the same period patient was treated with BRUFEN, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.


Avonex Side Effects Report #5318471-5
AVONEX problem was reported by a Consumer or non-health professional from on Apr 24, 2007. Male patient, 36 years of age, weighting 167.6 lb, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: accident, feeling abnormal, finger amputation, influenza like illness, limb injury, . AVONEX dosage: unknown. Patient was hospitalized. Patient recovered.

Chantix Side Effects Report #5281493-7
Physician from UNITED STATES reported CHANTIX problem on Mar 23, 2007. Female patient, 43 years of age, weighting 137.1 lb, was treated with CHANTIX. After drug was administered, patient experienced the following problems/side effects: blister, extremity necrosis, finger amputation, skin graft, . CHANTIX dosage: 0.5 MG DAILY PO. Patient was hospitalized. Patient recovered.