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METASTASES TO CENTRAL NERVOUS SYSTEM side effect

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Cetuximab Side Effects Report #5646740-8
Health Professional from GERMANY reported CETUXIMAB problem on Feb 21, 2008. Male patient, 75 years of age, was diagnosed with non-small cell lung cancer and was treated with CETUXIMAB. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, transient ischaemic attack, . CETUXIMAB dosage: unknown. During the same period patient was treated with CARBOPLATIN, GEMCITABINE. Patient was hospitalized. Patient recovered.

Cetuximab Side Effects Report #5682435-2
CETUXIMAB problem was reported by a Health Professional from GERMANY on Mar 19, 2008. Male patient, 75 years of age, weighting 167.6 lb, was diagnosed with non-small cell lung cancer and was treated with CETUXIMAB. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, transient ischaemic attack, . CETUXIMAB dosage: unknown. During the same period patient was treated with CARBOPLATIN, GEMCITABINE. Patient was hospitalized. Patient recovered.

Rebif Side Effects Report #5683333-0
Consumer or non-health professional from UNITED STATES reported REBIF problem on Mar 14, 2008. Female patient, 47 years of age, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, metastases to liver, metastatic malignant melanoma, . REBIF dosage: unknown. During the same period patient was treated with TYSABRI. Patient died on 02/20/2008.

Cetuximab Side Effects Report #5627480-8
CETUXIMAB problem was reported by a Health Professional from GERMANY on Feb 12, 2008. Male patient, 75 years of age, was diagnosed with non-small cell lung cancer and was treated with CETUXIMAB. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . CETUXIMAB dosage: unknown. During the same period patient was treated with CARBOPLATIN, GEMCITABINE. Patient was hospitalized. Patient recovered.


Arimidex Side Effects Report #5588276-9
Consumer or non-health professional from BRAZIL reported ARIMIDEX problem on Jan 10, 2008. Female patient, 51 years of age, was diagnosed with breast cancer and was treated with ARIMIDEX. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, metastases to lung, multi-organ failure, . ARIMIDEX dosage: unknown. Patient was hospitalized. Patient died on 12/30/2007.

Vagifem Side Effects Report #5589369-2
VAGIFEM problem was reported by a Physician from FRANCE on Jan 08, 2008. Female patient, weighting 196.2 lb, was diagnosed with atrophic vulvovaginitis, depression, venous stasis, arrhythmia and was treated with VAGIFEM. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . VAGIFEM dosage: unknown. During the same period patient was treated with EFFEXOR, DELURSAN, PREVISCAN, KERLONE. Patient died on 12/30/2007.

Herceptin Side Effects Report #5596187-8
Consumer or non-health professional from ITALY reported HERCEPTIN problem on Jan 15, 2008. Female patient, 36 years of age, was diagnosed with breast cancer, breast cancer metastatic and was treated with HERCEPTIN. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . HERCEPTIN dosage: 4 MG/KG, UNK. During the same period patient was treated with PACLITAXEL. Patient recovered.

Herceptin Side Effects Report #5548434-6
HERCEPTIN problem was reported by a Consumer or non-health professional from UNITED STATES on Dec 10, 2007. Female patient, 64 years of age, was treated with HERCEPTIN. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . HERCEPTIN dosage: unknown. Patient recovered.

Tarceva Side Effects Report #5573942-1
Health Professional from UNITED STATES reported TARCEVA problem on Dec 05, 2007. Female patient, 54 years of age, was treated with TARCEVA. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, metastasis, . TARCEVA dosage: (150 MG), ORAL. Patient died.


Herceptin Side Effects Report #5484207-0
HERCEPTIN problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 02, 2007. Female patient, 64 years of age, was treated with HERCEPTIN. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . HERCEPTIN dosage: unknown. Patient recovered.

Ketoconazole Side Effects Report #5444471-0
Physician from GERMANY reported KETOCONAZOLE problem on Sept 03, 2007. Female patient, 68 years of age, was diagnosed with blood cortisol increased and was treated with KETOCONAZOLE. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, off label use, . KETOCONAZOLE dosage: unknown. Patient died.

Sunitinib Side Effects Report #5423522-3
SUNITINIB problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 09, 2007. Female patient, 67 years of age, weighting 145.0 lb, was diagnosed with malignant melanoma, metastases to central nervous system and was treated with SUNITINIB. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, status epilepticus, . SUNITINIB dosage: 37.5MG DAILY PO. During the same period patient was treated with RADIATION, DECADRON, OXYCODONE. Patient was hospitalized. Patient died on 06/29/2007.

Bevacizumab Side Effects Report #5392592-3
Physician from UNITED STATES reported BEVACIZUMAB problem on July 11, 2007. Male patient was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, radiation pneumonitis, . BEVACIZUMAB dosage: 15 MG/KG, SINGLE. During the same period patient was treated with PACLITAXEL, CARBOPLATIN. Patient recovered.

Bevacizumab Side Effects Report #5392592-3
BEVACIZUMAB problem was reported by a Physician from UNITED STATES on July 11, 2007. Male patient was diagnosed with non-small cell lung cancer and was treated with BEVACIZUMAB. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, radiation pneumonitis, . BEVACIZUMAB dosage: 15 MG/KG, SINGLE. During the same period patient was treated with PACLITAXEL, CARBOPLATIN. Patient recovered.


Rebif Side Effects Report #5734764-1
Consumer or non-health professional from UNITED STATES reported REBIF problem on Apr 29, 2008. Female patient, 47 years of age, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, metastases to liver, metastatic malignant melanoma, . REBIF dosage: unknown. During the same period patient was treated with TYSABRI. Patient died on 02/20/2008.

Vagifem Side Effects Report #5690156-5
VAGIFEM problem was reported by a Physician from FRANCE on Jan 08, 2008. Female patient, weighting 196.2 lb, was diagnosed with atrophic vulvovaginitis, depression, venous stasis, arrhythmia and was treated with VAGIFEM. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . VAGIFEM dosage: unknown. During the same period patient was treated with EFFEXOR, DELURSAN, PREVISCAN, KERLONE. Patient died on 12/30/2007.

Zometa Side Effects Report #5699729-7
Physician from JAPAN reported ZOMETA problem on Mar 26, 2008. Female patient, 59 years of age, was diagnosed with metastases to bone and was treated with ZOMETA. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, osteomyelitis, tooth disorder, . ZOMETA dosage: 4 MG, QMO. During the same period patient was treated with THYRADIN, IRESSA. Patient recovered.

Zometa Side Effects Report #5716386-1
ZOMETA problem was reported by a Physician from JAPAN on Apr 16, 2008. Female patient, 59 years of age, was diagnosed with metastases to bone and was treated with ZOMETA. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, osteomyelitis, tooth disorder, . ZOMETA dosage: 4 MG, QMO. During the same period patient was treated with THYRADIN, IRESSA. Patient recovered.

Leuprolide Side Effects Report #5377766-X
Consumer or non-health professional from JAPAN reported LEUPROLIDE ACETATE problem on June 21, 2007. Male patient, 74 years of age, was diagnosed with prostate cancer stage iv and was treated with LEUPROLIDE ACETATE. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, metastases to lung, . LEUPROLIDE ACETATE dosage: 11.25 MG (11.25 MG, 1 IN 12 WK) SUBCUTANEOUS. During the same period patient was treated with CASODEX. Patient died.


Rebif Side Effects Report #5333457-2
REBIF problem was reported by a Physician from UNITED STATES on May 15, 2007. Female patient, 60 years of age, weighting 207.0 lb, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, metastatic neoplasm, . REBIF dosage: unknown. During the same period patient was treated with COPAXONE. Patient died on 09/02/2005.

Rebif Side Effects Report #5334488-9
Physician from UNITED STATES reported REBIF problem on May 15, 2007. Female patient, 60 years of age, weighting 207.0 lb, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, neoplasm malignant, . REBIF dosage: unknown. During the same period patient was treated with COPAXONE. Patient died on 09/02/2005.

Rebif Side Effects Report #5343723-2
REBIF problem was reported by a Physician from UNITED STATES on May 18, 2007. Female patient, 60 years of age, weighting 207.0 lb, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, neoplasm malignant, nervous system disorder, . REBIF dosage: unknown. During the same period patient was treated with COPAXONE. Patient died on 09/02/2005.

Gleevec Side Effects Report #5305290-9
Consumer or non-health professional from JAPAN reported GLEEVEC problem on Apr 11, 2007. Male patient, 76 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, osteomyelitis fungal, . GLEEVEC dosage: 400 MG/D. Patient recovered.

Gleevec Side Effects Report #5305847-5
GLEEVEC problem was reported by a Consumer or non-health professional from JAPAN on Apr 11, 2007. Male patient, 76 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, osteomyelitis fungal, . GLEEVEC dosage: 400 MG/D. Patient recovered.

Iressa Side Effects Report #5263436-5
Physician from UNITED STATES reported IRESSA problem on Sept 03, 2004. Male patient, 64 years of age, was treated with IRESSA. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, metastases to liver, . IRESSA dosage: unknown. During the same period patient was treated with CAMPTOSAR. Patient recovered.

Iressa Side Effects Report #5263516-4
IRESSA problem was reported by a Consumer or non-health professional from UNITED STATES on Jan 19, 2004. Female patient was diagnosed with neoplasm and was treated with IRESSA. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . IRESSA dosage: 250 MG PO. Patient recovered.

Nolvadex Side Effects Report #5267954-5
Physician from UNITED STATES reported NOLVADEX problem on June 03, 2002. Female patient, 71 years of age, was treated with NOLVADEX. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . NOLVADEX dosage: unknown. Patient died on 08/30/2001.

Iressa Side Effects Report #5268464-1
IRESSA problem was reported by a Consumer or non-health professional from UNITED STATES on Sept 23, 2004. Female patient, 69 years of age, weighting 140.0 lb, was diagnosed with non-small cell lung cancer and was treated with IRESSA. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . IRESSA dosage: 250 MG PO. Patient was hospitalized. Patient recovered.

Nexavar Side Effects Report #5655328-4
Consumer or non-health professional from UNITED STATES reported NEXAVAR problem on Feb 26, 2008. Female patient, 72 years of age, was diagnosed with renal cell carcinoma and was treated with NEXAVAR. After drug was administered, patient experienced the following problems/side effects: cardiac disorder, metastases to central nervous system, metastases to liver, metastases to lung, metastasis, thrombosis, . NEXAVAR dosage: TOTAL DAILY DOSE: 400 MG UNIT DOSE: 200 MG. During the same period patient was treated with DIGITEK, SOTALOL, NEXIUM, ARICEPT, ALLEGRA, WARFARIN. Patient recovered.

Revlimid Side Effects Report #5679894-8
REVLIMID problem was reported by a Health Professional from GERMANY on Mar 17, 2008. Male patient was diagnosed with multiple myeloma and was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: lung neoplasm, metastases to central nervous system, . REVLIMID dosage: 25 MG, ORAL. Patient recovered.

Humira Side Effects Report #5622429-6
Consumer or non-health professional from GERMANY reported HUMIRA problem on Jan 30, 2008. Female patient, 54 years of age, was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: inflammatory carcinoma of breast stage iv, metastases to central nervous system, metastases to liver, . HUMIRA dosage: unknown. During the same period patient was treated with INFLIXIMAB, ETANERCEPT, METHOTREXATE. Patient was hospitalized. Patient died on 05/15/2007.

Remicade Side Effects Report #5595395-X
REMICADE problem was reported by a Health Professional from PORTUGAL on Jan 10, 2008. Female patient, 41 years of age, was diagnosed with ankylosing spondylitis and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: metastases to bone, metastases to central nervous system, metastases to liver, metastases to lung, metastasis, salivary gland cancer, . REMICADE dosage: unknown. Patient died on 08/09/2007.

Revlimid Side Effects Report #5506970-2
Physician from UNITED STATES reported REVLIMID problem on Oct 24, 2007. Female patient, 63 years of age, was diagnosed with multiple myeloma and was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, metastases to central nervous system, metastasis, multiple myeloma, . REVLIMID dosage: 25 MG, QD, ORAL. During the same period patient was treated with DEXAMETHASONE, VICODIN. Patient died on 09/09/2007.

Tarceva Side Effects Report #5512594-3
TARCEVA problem was reported by a Physician from NETHERLANDS on Oct 22, 2007. Female patient, 73 years of age, was treated with TARCEVA. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, metastases to central nervous system, skin ulcer, . TARCEVA dosage: unknown. Patient died.

Thalomid Side Effects Report #5518882-9
Physician from UNITED STATES reported THALOMID problem on Nov 06, 2007. Female patient, 78 years of age, was diagnosed with lymphoma and was treated with THALOMID. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, multiple myeloma, neuralgia, . THALOMID dosage: 100 MG, 1 IN 1 D, ORAL ; 200 MG, 1 IN 1 D, ORAL ; ORAL. Patient recovered.

Lasix Side Effects Report #5519269-5
LASIX problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 12, 2007. Female patient was diagnosed with lung cancer metastatic and was treated with LASIX. After drug was administered, patient experienced the following problems/side effects: dehydration, metastases to central nervous system, paraesthesia, . LASIX dosage: unknown. During the same period patient was treated with THALOMID, TARCEVA, DECADRON, VITAMINS. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5521526-3
Health Professional from UNITED STATES reported TEMODAR problem on Nov 16, 2007. Female patient, 65 years of age, weighting 141.0 lb, was diagnosed with malignant melanoma and was treated with TEMODAR. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, metastases to central nervous system, metastases to lung, metastatic malignant melanoma, pneumonia staphylococcal, . TEMODAR dosage: 170MG PO DAILY. During the same period patient was treated with SUTENT. Patient was hospitalized. Patient died on 08/12/2007.

Intron Side Effects Report #5526282-0
INTRON A problem was reported by a Consumer or non-health professional from UNITED STATES on Nov 21, 2007. Male patient, weighting 205.5 lb, was treated with INTRON A. After drug was administered, patient experienced the following problems/side effects: depressed level of consciousness, metastases to central nervous system, . INTRON A dosage: 2684.5 MILLION IU. Patient was hospitalized. Patient recovered.

Procrit Side Effects Report #5529454-4
Physician from UNITED STATES reported PROCRIT problem on Nov 19, 2007. Female patient, 52 years of age, was diagnosed with anaemia of malignant disease and was treated with PROCRIT. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, . PROCRIT dosage: unknown. During the same period patient was treated with DEXAMETHASONE. Patient recovered.

Gliadel Side Effects Report #5484879-0
GLIADEL problem was reported by a Physician from SPAIN on Dec 05, 2006. Male patient, 63 years of age, was diagnosed with glioblastoma multiforme and was treated with GLIADEL. After drug was administered, patient experienced the following problems/side effects: intracranial pressure increased, metastases to central nervous system, pneumocephalus, . GLIADEL dosage: unknown. Patient died.

Leuplin Side Effects Report #5491362-5
Physician from JAPAN reported LEUPLIN problem on Oct 11, 2007. Male patient, 74 years of age, was diagnosed with prostate cancer stage iv and was treated with LEUPLIN. After drug was administered, patient experienced the following problems/side effects: condition aggravated, metastases to central nervous system, metastases to lung, prostate cancer stage iv, . LEUPLIN dosage: 11.25 MG (11.25 MG, 1 IN 12 WK) SUBCUTANEOUS. During the same period patient was treated with CASODEX. Patient died.

Zyprexa Side Effects Report #5447237-0
ZYPREXA problem was reported by a Physician from JAPAN on Aug 29, 2007. Female patient, 62 years of age, was diagnosed with major depression and was treated with ZYPREXA. After drug was administered, patient experienced the following problems/side effects: malaise, metastases to central nervous system, somnolence, . ZYPREXA dosage: 5 MG, DAILY (1/D). During the same period patient was treated with MILNACIPRAN, MAPROTILINE, AMITRIPTYLINE, ETIZOLAM. Patient was hospitalized. Patient recovered.

Propranolol Side Effects Report #5447360-0
Physician from INDIA reported PROPRANOLOL problem on Sept 05, 2007. Male patient, 58 years of age, was diagnosed with cachexia and was treated with PROPRANOLOL. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, metastases to central nervous system, non-small cell lung cancer, . PROPRANOLOL dosage: 40MG 20MG BREAKFAST 10MG LUNCH 10MG EVENING ORAL. During the same period patient was treated with ETODOLAC, FAMOTIDINE, NEUROBION. Patient was hospitalized. Patient recovered.

Thalomid Side Effects Report #5453511-4
THALOMID problem was reported by a Physician from UNITED STATES on Sept 06, 2007. Female patient, 78 years of age, was diagnosed with lymphoma and was treated with THALOMID. After drug was administered, patient experienced the following problems/side effects: metastases to central nervous system, multiple myeloma, neuralgia, . THALOMID dosage: 100 MG, 1 IN 1 D, ORAL; 200 MG, 1 IN 1 D, ORAL; ORAL. Patient recovered.

Avastin Side Effects Report #5456619-2
Consumer or non-health professional from UNITED KINGDOM reported AVASTIN problem on Sept 04, 2007. Female patient, weighting 172.6 lb, was diagnosed with breast cancer metastatic and was treated with AVASTIN. After drug was administered, patient experienced the following problems/side effects: dermatitis acneiform, metastases to central nervous system, . AVASTIN dosage: 780 MG, QD. During the same period patient was treated with PACLITAXEL. Patient recovered.

Remicade Side Effects Report #5413475-6
REMICADE problem was reported by a Health Professional from UNITED KINGDOM on Aug 03, 2007. Male patient, 60 years of age, was diagnosed with rheumatoid arthritis and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm of thorax, metastases to central nervous system, . REMICADE dosage: unknown. During the same period patient was treated with ETANERCEPT, PREDNISOLONE, CALCICHEW, METHOTREXATE, FOLIC ACID, VENTOLIN, BECOTIDE. Patient recovered.

Enbrel Side Effects Report #5420825-3
Physician from UNITED KINGDOM reported ENBREL problem on Aug 14, 2007. Male patient, weighting 144.0 lb, was diagnosed with rheumatoid arthritis, emphysema, asthma and was treated with ENBREL. After drug was administered, patient experienced the following problems/side effects: lung cancer metastatic, metastases to central nervous system, . ENBREL dosage: unknown. During the same period patient was treated with METHOTREXATE, VENTOLIN, BECOTIDE, ASCORBIC ACID, FOLIC ACID, PREDNISOLONE. Patient recovered.

Rabeprazole Side Effects Report #5422316-2
RABEPRAZOLE problem was reported by a Physician from JAPAN on Aug 06, 2007. Male patient, 64 years of age, was diagnosed with reflux oesophagitis and was treated with RABEPRAZOLE. After drug was administered, patient experienced the following problems/side effects: memory impairment, metastases to central nervous system, neoplasm malignant, . RABEPRAZOLE dosage: 10 MG, 1 IN 1 D, ORAL. Patient was hospitalized. Patient recovered.

Remicade Side Effects Report #5425910-8
Health Professional from UNITED KINGDOM reported REMICADE problem on Aug 16, 2007. Male patient, weighting 154.3 lb, was diagnosed with rheumatoid arthritis and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: lung neoplasm malignant, metastases to central nervous system, . REMICADE dosage: unknown. During the same period patient was treated with ASCORBIC ACID, TRAMADOL, METHOTREXATE, PREDNISOLONE, BECOTIDE, CALCICHEW, CODYDRAMOL, FOLIC ACID. Patient recovered.

Etoposide Side Effects Report #5444318-2
ETOPOSIDE problem was reported by a Physician from ISRAEL on Aug 23, 2007. Male patient, 20 years of age, was diagnosed with neoplasm malignant, ovarian cancer and was treated with ETOPOSIDE. After drug was administered, patient experienced the following problems/side effects: glioblastoma multiforme, metastases to central nervous system, . ETOPOSIDE dosage: 75 MG/M2, DAILY X 3 COURSES. During the same period patient was treated with CARBOPLATIN, CISPLATIN, CYCLOPHOSPHAMIDE, VINCRISTINE. Patient died on 08/01/2005.

Faslodex Side Effects Report #5382503-9
Consumer or non-health professional from UNITED STATES reported FASLODEX problem on July 05, 2007. Female patient, 51 years of age, was diagnosed with breast cancer and was treated with FASLODEX. After drug was administered, patient experienced the following problems/side effects: hepatorenal syndrome, metastases to central nervous system, . FASLODEX dosage: unknown. During the same period patient was treated with SPIRONOLACTONE, LORTAB, NADOLOL, ZOFRAN, VITAMIN B6. Patient died on 04/02/2007.