PLEURISY side effect
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Drugs associated with PLEURISY
ABATACEPT ACTOS ADVAIR ALBUTEROL ALKERAN APRANAX ARAVA ARIXTRA AVANDAMET AVONEX AZMACORT BOTOX BYETTA CABASER CAP CARBOPLATIN CHAMPIX CHANTIX CRESTOR DACTINOMYCIN DURAGESIC ENBREL ENDOXAN EVISTA FORTEO GLEEVEC HERCEPTIN HUMIRA INFLIXIMAB IRESSA LIPITOR MABTHERA MACRODANTIN MICARDIS NICOTINELL NUVARING ORLISTAT OXYCONTIN PEGASYS PEMETREXED PENTASA PROGRAF RANITIDINE REBIF REMICADE REVLIMID RIBASPHERE SINGULAIR SUTENT SYMBICORT TARCEVA TOSITUMOMAB TRETINOIN TRISENOX TYSABRI VORICONAZOLE WELLBUTRIN XENICAL ZEMAIRA ZEVALINRevlimid Side Effects Report #5639440-1
Health Professional from UNITED STATES reported REVLIMID problem on Feb 14, 2008. Male patient, 75 years of age, was diagnosed with multiple myeloma and was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: pleurisy, . REVLIMID dosage: 25 MG, DAILY FOR 21 DAYS, ORAL. Patient recovered.
Remicade Side Effects Report #5541629-7
REMICADE problem was reported by a Health Professional from FRANCE on Nov 30, 2007. Male patient, weighting 132.3 lb, was diagnosed with ankylosing spondylitis, inflammatory pain and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: pleurisy, tuberculosis, . REMICADE dosage: unknown. During the same period patient was treated with METHOTREXATE, SPECIAFOLDINE. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5557978-2
Consumer or non-health professional from BELGIUM reported HUMIRA problem on Dec 06, 2007. Female patient, weighting 143.3 lb, was diagnosed with rheumatoid arthritis, vitamin supplementation, hyperlipidaemia, depression and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, . HUMIRA dosage: unknown. During the same period patient was treated with METHOTREXATE, FOLIC ACID, ATORVASTATIN CALCIUM, METOPROLOL SUCCINATE, COMMERCIAL HUMIRA. Patient was hospitalized. Patient recovered.
Lipitor Side Effects Report #5567705-0
LIPITOR problem was reported by a Physician from SOUTH AFRICA on Dec 11, 2007. Male patient, 36 years of age, was diagnosed with dyslipidaemia and was treated with LIPITOR. After drug was administered, patient experienced the following problems/side effects: pleurisy, . LIPITOR dosage: unknown. Patient recovered.
Voriconazole Side Effects Report #5506867-8
Consumer or non-health professional from FRANCE reported VORICONAZOLE problem on Oct 24, 2007. Male patient, 56 years of age, was diagnosed with lung abscess and was treated with VORICONAZOLE. After drug was administered, patient experienced the following problems/side effects: pleurisy, . VORICONAZOLE dosage: unknown. Patient recovered.
Remicade Side Effects Report #5514015-3
REMICADE problem was reported by a Health Professional from FRANCE on Nov 05, 2007. Male patient, weighting 132.3 lb, was diagnosed with ankylosing spondylitis, inflammatory pain and was treated with REMICADE. After drug was administered, patient experienced the following problems/side effects: pleurisy, tuberculosis, . REMICADE dosage: unknown. During the same period patient was treated with METHOTREXATE, SPECIAFOLDINE. Patient was hospitalized. Patient recovered.
Tarceva Side Effects Report #5518675-2
Pharmacist from BELGIUM reported TARCEVA problem on Oct 29, 2007. Male patient was treated with TARCEVA. After drug was administered, patient experienced the following problems/side effects: pleurisy, . TARCEVA dosage: unknown. Patient recovered.
Oxycontin Side Effects Report #5527980-5
OXYCONTIN problem was reported by a Physician from NETHERLANDS on Nov 19, 2007. Male patient, 46 years of age, was diagnosed with cervical root pain and was treated with OXYCONTIN. After drug was administered, patient experienced the following problems/side effects: pleurisy, . OXYCONTIN dosage: 5 MG, DAILY. During the same period patient was treated with DICLOFENAC. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5483157-3
Consumer or non-health professional from UNITED KINGDOM reported HUMIRA problem on Oct 03, 2007. Male patient, weighting 213.8 lb, was diagnosed with rheumatoid arthritis and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, . HUMIRA dosage: unknown. During the same period patient was treated with PREDNISOLONE, ALENDRONATE, AMITRIPTYLINE, ACETYLSALICYLIC ACID, ACETYLSALICYLIC ACID, ATENOLOL. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5484230-6
HUMIRA problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 02, 2007. Female patient, weighting 123.5 lb, was diagnosed with rheumatoid arthritis and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, pneumonia, . HUMIRA dosage: unknown. During the same period patient was treated with SULFASALAZINE, METHOTREXATE, DICLOFENAC, FOLIC ACID, PARACETAMOL. Patient was hospitalized. Patient recovered.
Enbrel Side Effects Report #5501766-X
Physician from JAPAN reported ENBREL problem on Oct 18, 2007. Female patient, weighting 132.3 lb, was diagnosed with rheumatoid arthritis and was treated with ENBREL. After drug was administered, patient experienced the following problems/side effects: pleurisy, . ENBREL dosage: unknown. During the same period patient was treated with CYTOTEC, SULFASALAZINE, LOXONIN. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5473074-7
TRISENOX problem was reported by a Physician from JAPAN on Sept 19, 2007. Female patient, 28 years of age, was treated with TRISENOX. After drug was administered, patient experienced the following problems/side effects: pleurisy, pyrexia, . TRISENOX dosage: unknown. Patient recovered.
Forteo Side Effects Report #5407400-1
Consumer or non-health professional from FRANCE reported FORTEO problem on July 31, 2007. Female patient, 62 years of age, was diagnosed with osteoporosis and was treated with FORTEO. After drug was administered, patient experienced the following problems/side effects: pleurisy, . FORTEO dosage: unknown. Patient was hospitalized. Patient recovered.
Rebif Side Effects Report #5420626-6
REBIF problem was reported by a Consumer or non-health professional from UNITED STATES on Aug 07, 2007. Female patient, 48 years of age, was diagnosed with multiple sclerosis and was treated with REBIF. After drug was administered, patient experienced the following problems/side effects: pleurisy, systemic lupus erythematosus, . REBIF dosage: unknown. During the same period patient was treated with DETROL, PROVIGIL. Patient recovered.
Abatacept Side Effects Report #5759907-5
Consumer or non-health professional from AUSTRALIA reported ABATACEPT problem on June 03, 2008. Female patient, 50 years of age, was diagnosed with systemic lupus erythematosus and was treated with ABATACEPT. After drug was administered, patient experienced the following problems/side effects: pleurisy, . ABATACEPT dosage: unknown. During the same period patient was treated with HYDROXYCHLOROQUINE SULPHATE, ASPIRIN, TRAMADOL, OXYCODONE, TEMAZEPAM, RABEPRAZOLE, SERTRALINE, ACETAMINOPHEN. Patient was hospitalized. Patient recovered.
Iressa Side Effects Report #5762751-6
IRESSA problem was reported by a Physician from JAPAN on June 05, 2008. Female patient, 60 years of age, was diagnosed with lung neoplasm malignant and was treated with IRESSA. After drug was administered, patient experienced the following problems/side effects: pleurisy, . IRESSA dosage: unknown. Patient recovered.
Iressa Side Effects Report #5764991-9
Physician from JAPAN reported IRESSA problem on June 03, 2008. Female patient, weighting 112.4 lb, was diagnosed with lung adenocarcinoma and was treated with IRESSA. After drug was administered, patient experienced the following problems/side effects: pleurisy, pneumonia, . IRESSA dosage: unknown. During the same period patient was treated with CALSLOT, LENDORMIN, CLEANAL, PREDONINE. Patient was hospitalized. Patient recovered.
Symbicort Side Effects Report #5776643-X
SYMBICORT problem was reported by a Physician from UNITED STATES on Feb 26, 2008. Male patient, child 12 years of age, was treated with SYMBICORT. After drug was administered, patient experienced the following problems/side effects: pleurisy, . SYMBICORT dosage: unknown. Patient recovered.
Revlimid Side Effects Report #5735999-4
Physician from UNITED STATES reported REVLIMID problem on May 02, 2008. Male patient, 75 years of age, was diagnosed with multiple myeloma and was treated with REVLIMID. After drug was administered, patient experienced the following problems/side effects: pleurisy, . REVLIMID dosage: 25 MG, DAILY FOR 21 DAYS, ORAL. Patient recovered.
Orlistat Side Effects Report #5708248-0
ORLISTAT problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 09, 2008. Female patient, weighting 210.1 lb, was diagnosed with obesity, hypertension and was treated with ORLISTAT. After drug was administered, patient experienced the following problems/side effects: pleurisy, pulmonary oedema, . ORLISTAT dosage: unknown. During the same period patient was treated with ASPIRIN, ZANIDIP, PRITOR, LEVOTHYROXINE, FUROSEMIDE, DOXYCYCLINE. Patient was hospitalized. Patient recovered.
Singulair Side Effects Report #5719258-1
Pharmacist from UNITED STATES reported SINGULAIR problem on Sept 13, 2007. Female patient was treated with SINGULAIR. After drug was administered, patient experienced the following problems/side effects: pleurisy, . SINGULAIR dosage: 10 MG/DAILY/PO. During the same period patient was treated with ALLEGRA, SYNTHROID, DOXYCYCLINE, VENLAFAXINE HYDROCHLORIDE. Patient recovered.
Advair Side Effects Report #5314784-1
ADVAIR DISKUS problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 27, 2007. Female patient, 80 years of age, was diagnosed with asthma and was treated with ADVAIR DISKUS. After drug was administered, patient experienced the following problems/side effects: pleurisy, pneumonia, . ADVAIR DISKUS dosage: unknown. During the same period patient was treated with PRINIVIL. Patient recovered.
Humira Side Effects Report #5322832-8
Physician from FRANCE reported HUMIRA problem on May 03, 2007. Male patient, weighting 149.9 lb, was diagnosed with rheumatoid arthritis, analgesic effect, diabetes mellitus non-insulin-dependent and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, pulmonary tuberculosis, . HUMIRA dosage: unknown. During the same period patient was treated with PREDNISONE, METHOTREXATE, CELECOXIB, FOLIC ACID, GLIBENCLAMIDE. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5285346-X
HUMIRA problem was reported by a Health Professional from UNITED KINGDOM on Mar 26, 2007. Female patient, weighting 174.2 lb, was diagnosed with rheumatoid arthritis and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, . HUMIRA dosage: unknown. During the same period patient was treated with METHOTREXATE, PREDNISOLONE, CODEINE, FOLIC ACID, OMEPRAZOLE, ACETAMINOPHEN, ROFECOXIB. Patient recovered.
Carboplatin Side Effects Report #5300400-1
Consumer or non-health professional from UNITED STATES reported CARBOPLATIN problem on Apr 17, 2007. Female patient, 60 years of age, weighting 112.4 lb, was diagnosed with ovarian cancer and was treated with CARBOPLATIN. After drug was administered, patient experienced the following problems/side effects: pleurisy, splenic rupture, . CARBOPLATIN dosage: unknown. During the same period patient was treated with DOXORUBICIN, NEULASTA. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5303663-1
HUMIRA problem was reported by a Health Professional from UNITED KINGDOM on Apr 10, 2007. Female patient, weighting 160.9 lb, was diagnosed with rheumatoid arthritis and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, pneumonia, . HUMIRA dosage: unknown. During the same period patient was treated with PREDNISOLONE, AZITHROMYCIN, BENDROFLUMETHIAZIDE, FLIXOTIDE, PARACETAMOL, FELODIPINE, SALBUTAMOL, LEVOTHYROXINE. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5253811-7
Consumer or non-health professional from GERMANY reported HUMIRA problem on Feb 23, 2007. Female patient, weighting 198.4 lb, was diagnosed with rheumatoid arthritis, hyperthyroidism, hypothyroidism, meniere's disease and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, pneumonitis, . HUMIRA dosage: unknown. During the same period patient was treated with COMERCIAL HUMIRA, L THYROXCIN, VINCAMIN, DECORTIN. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5259426-9
HUMIRA problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 26, 2007. Female patient, weighting 160.9 lb, was diagnosed with rheumatoid arthritis and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: pleurisy, pneumonia, . HUMIRA dosage: unknown. During the same period patient was treated with PREDNISOLONE, AZITHROMYCIN, BENDROFLUMETHIAZIDE, FLIXOTIDE, ACETAMINOPHEN, FELODIPINE, SALBUTAMOL, LEVOTHYROXINE. Patient was hospitalized. Patient recovered.
Pentasa Side Effects Report #5271893-3
Physician from JAPAN reported PENTASA problem on Mar 02, 2007. Female patient, child 10 years of age, was diagnosed with crohn's disease and was treated with PENTASA. After drug was administered, patient experienced the following problems/side effects: pleurisy, . PENTASA dosage: 500 MG 3XS DAILY, ORAL. Patient was hospitalized. Patient recovered.
Enbrel Side Effects Report #5281614-6
ENBREL problem was reported by a Physician from JAPAN on Mar 20, 2007. Male patient, weighting 116.8 lb, was diagnosed with rheumatoid arthritis, antibiotic prophylaxis and was treated with ENBREL. After drug was administered, patient experienced the following problems/side effects: pleurisy, . ENBREL dosage: unknown. During the same period patient was treated with RHEUMATREX, PREDONINE, ISCOTIN, LOXONIN, ULGUT. Patient was hospitalized. Patient recovered.
Humira Side Effects Report #5668412-6
Consumer or non-health professional from UNITED STATES reported HUMIRA problem on Feb 25, 2008. Female patient, weighting 150.1 lb, was diagnosed with rheumatoid arthritis and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: bronchiectasis, pleurisy, pleuritic pain, . HUMIRA dosage: unknown. During the same period patient was treated with METHOTREXATE, LEVOTHYROXINE, DICLOFENAC, ESOMEPRAZOLE MAGNESIUM. Patient recovered.
Infliximab Side Effects Report #5675473-7
INFLIXIMAB problem was reported by a Physician from GERMANY on Mar 12, 2008. Male patient, weighting 167.6 lb, was diagnosed with psoriasis and was treated with INFLIXIMAB. After drug was administered, patient experienced the following problems/side effects: lymphoma, pleurisy, pulmonary embolism, . INFLIXIMAB dosage: unknown. Patient was hospitalized. Patient recovered.
Avonex Side Effects Report #5679772-4
Consumer or non-health professional from UNITED STATES reported AVONEX problem on Mar 10, 2008. Female patient, 56 years of age, weighting 115.0 lb, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: no therapeutic response, pleurisy, pneumonia, white blood cell count increased, . AVONEX dosage: unknown. During the same period patient was treated with PLASMA, AZITHROMYCIN. Patient was hospitalized. Patient recovered.
Infliximab Side Effects Report #5682372-3
INFLIXIMAB problem was reported by a Physician from GERMANY on Mar 18, 2008. Male patient, weighting 167.6 lb, was diagnosed with psoriasis and was treated with INFLIXIMAB. After drug was administered, patient experienced the following problems/side effects: lymphoma, pleurisy, pulmonary embolism, . INFLIXIMAB dosage: unknown. Patient was hospitalized. Patient recovered.
Infliximab Side Effects Report #5630291-0
Physician from GERMANY reported INFLIXIMAB problem on Feb 13, 2008. Male patient, weighting 167.6 lb, was diagnosed with psoriasis and was treated with INFLIXIMAB. After drug was administered, patient experienced the following problems/side effects: lymphoma, pleurisy, pulmonary embolism, . INFLIXIMAB dosage: unknown. Patient was hospitalized. Patient recovered.
Prograf Side Effects Report #5584746-8
PROGRAF problem was reported by a Physician from JAPAN on Dec 19, 2007. Male patient, child 5 years of age, was treated with PROGRAF. After drug was administered, patient experienced the following problems/side effects: interstitial lung disease, pleurisy, . PROGRAF dosage: 0.03 MG/KG, /D, IV NOS. During the same period patient was treated with PREDNISOLONE. Patient recovered.
Alkeran Side Effects Report #5588783-9
Physician from JAPAN reported ALKERAN problem on Jan 10, 2008. Female patient, 26 years of age, weighting 123.5 lb, was diagnosed with immunosuppression and was treated with ALKERAN. After drug was administered, patient experienced the following problems/side effects: hepatic failure, pleurisy, . ALKERAN dosage: 60MGM2 PER DAY. During the same period patient was treated with BUSULFAN, TACROLIMUS HYDRATE, ALOSITOL, GASTER, CRAVIT, DIFLUCAN, ZOVIRAX. Patient was hospitalized. Patient died on 04/18/2002.
Botox Side Effects Report #5553681-3
BOTOX problem was reported by a Physician from JAPAN on Dec 07, 2007. Male patient was diagnosed with muscle spasms and was treated with BOTOX. After drug was administered, patient experienced the following problems/side effects: cholecystitis, pleurisy, . BOTOX dosage: unknown. Patient was hospitalized. Patient recovered.
Infliximab Side Effects Report #5566324-X
Physician from GERMANY reported INFLIXIMAB problem on Dec 07, 2007. Male patient, weighting 167.6 lb, was diagnosed with psoriasis and was treated with INFLIXIMAB. After drug was administered, patient experienced the following problems/side effects: lymphoma, pleurisy, pulmonary embolism, . INFLIXIMAB dosage: unknown. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5506363-8
TRISENOX problem was reported by a Physician from JAPAN on Oct 18, 2007. Female patient, 28 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with TRISENOX. After drug was administered, patient experienced the following problems/side effects: neuropathy peripheral, pleurisy, . TRISENOX dosage: 10.05 MG QD INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.
Avonex Side Effects Report #5491789-1
Consumer or non-health professional from UNITED STATES reported AVONEX problem on Oct 09, 2007. Female patient, 48 years of age, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: myalgia, pleurisy, . AVONEX dosage: unknown. Patient was hospitalized. Patient recovered.
Tretinoin Side Effects Report #5413248-4
TRETINOIN problem was reported by a Physician from ITALY on Aug 08, 2007. Male patient, weighting 167.6 lb, was diagnosed with acute promyelocytic leukaemia, prophylaxis and was treated with TRETINOIN. After drug was administered, patient experienced the following problems/side effects: colitis, pleurisy, septic shock, . TRETINOIN dosage: unknown. During the same period patient was treated with ALLOPURINOL, VANCOMYCIN, CEFTAZIDIME, AMIKACIN, IDARUBICIN, ITRACONAZOLE. Patient was hospitalized. Patient recovered.
Avonex Side Effects Report #5382094-2
Consumer or non-health professional from UNITED STATES reported AVONEX problem on June 26, 2007. Female patient, 55 years of age, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: cystitis, pleurisy, urinary tract infection, . AVONEX dosage: unknown. Patient was hospitalized. Patient recovered.
Gleevec Side Effects Report #5388037-X
GLEEVEC problem was reported by a Pharmacist from JAPAN on July 11, 2007. Male patient, 79 years of age, was diagnosed with chronic myeloid leukaemia, tuberculosis and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pleurisy, renal failure, . GLEEVEC dosage: 400 MG/D. During the same period patient was treated with RIFAMPICIN. Patient died on 04/23/2007.
Gleevec Side Effects Report #5388561-X
Pharmacist from JAPAN reported GLEEVEC problem on July 11, 2007. Male patient, 79 years of age, was diagnosed with chronic myeloid leukaemia, tuberculosis and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pleurisy, renal failure, . GLEEVEC dosage: 400 MG/D. During the same period patient was treated with RIFAMPICIN. Patient died on 04/23/2007.
Actos Side Effects Report #5391803-8
ACTOS problem was reported by a Health Professional from GERMANY on July 04, 2007. Female patient, 66 years of age, was diagnosed with type 2 diabetes mellitus and was treated with ACTOS. After drug was administered, patient experienced the following problems/side effects: pleural effusion, pleurisy, . ACTOS dosage: 30 MG (30 MG, 1 IN 1 D); PER ORAL. During the same period patient was treated with STARLIX, METFORMIN. Patient was hospitalized. Patient recovered.
Avonex Side Effects Report #5382094-2
Consumer or non-health professional from UNITED STATES reported AVONEX problem on June 26, 2007. Female patient, 55 years of age, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: cystitis, pleurisy, urinary tract infection, . AVONEX dosage: unknown. Patient was hospitalized. Patient recovered.
Gleevec Side Effects Report #5388037-X
GLEEVEC problem was reported by a Pharmacist from JAPAN on July 11, 2007. Male patient, 79 years of age, was diagnosed with chronic myeloid leukaemia, tuberculosis and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pleurisy, renal failure, . GLEEVEC dosage: 400 MG/D. During the same period patient was treated with RIFAMPICIN. Patient died on 04/23/2007.
Gleevec Side Effects Report #5388561-X
Pharmacist from JAPAN reported GLEEVEC problem on July 11, 2007. Male patient, 79 years of age, was diagnosed with chronic myeloid leukaemia, tuberculosis and was treated with GLEEVEC. After drug was administered, patient experienced the following problems/side effects: platelet count decreased, pleurisy, renal failure, . GLEEVEC dosage: 400 MG/D. During the same period patient was treated with RIFAMPICIN. Patient died on 04/23/2007.
Actos Side Effects Report #5391803-8
ACTOS problem was reported by a Health Professional from GERMANY on July 04, 2007. Female patient, 66 years of age, was diagnosed with type 2 diabetes mellitus and was treated with ACTOS. After drug was administered, patient experienced the following problems/side effects: pleural effusion, pleurisy, . ACTOS dosage: 30 MG (30 MG, 1 IN 1 D); PER ORAL. During the same period patient was treated with STARLIX, METFORMIN. Patient was hospitalized. Patient recovered.
Herceptin Side Effects Report #5760023-7
Physician from UNITED KINGDOM reported HERCEPTIN problem on May 27, 2008. Female patient was diagnosed with breast cancer and was treated with HERCEPTIN. After drug was administered, patient experienced the following problems/side effects: pericarditis, pleurisy, . HERCEPTIN dosage: 6 MG/KG, UNK. Patient recovered.