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RECTAL PERFORATION side effect

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Avastin Side Effects Report #5720032-0
Physician from UNITED STATES reported AVASTIN problem on Apr 10, 2007. Female patient, 54 years of age, was diagnosed with colorectal cancer metastatic and was treated with AVASTIN. After drug was administered, patient experienced the following problems/side effects: impaired healing, rectal perforation, sepsis, . AVASTIN dosage: 343 MG, Q2W, INTRAVENOUS. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, OXALIPLATIN, ARANSEP, COMPAZINE, COUMADIN, NEXIUM. Patient was hospitalized. Patient recovered.

Avastin Side Effects Report #5338217-4
AVASTIN problem was reported by a Physician from UNITED STATES on Feb 05, 2007. Female patient, 54 years of age, was diagnosed with colorectal cancer metastatic and was treated with AVASTIN. After drug was administered, patient experienced the following problems/side effects: impaired healing, rectal perforation, sepsis, . AVASTIN dosage: unknown. During the same period patient was treated with FLUOROURACIL, LEUCOVORIN CALCIUM, OXALIPLATIN, ARANESP, COMPAZINE, COUMADIN, NEXIUM, COLACE. Patient was hospitalized. Patient recovered.

Isovorin Side Effects Report #5602097-X
Health Professional from JAPAN reported ISOVORIN problem on Jan 16, 2008. Female patient, 54 years of age, was diagnosed with rectal cancer metastatic and was treated with ISOVORIN. After drug was administered, patient experienced the following problems/side effects: gastrointestinal perforation, peritonitis, rectal perforation, . ISOVORIN dosage: 100 MG. During the same period patient was treated with FLUOROURACIL, AVASTIN, ELPLAT. Patient recovered.

Voltaren Side Effects Report #5746496-4
VOLTAREN problem was reported by a Physician from JAPAN on May 14, 2008. Male patient, 62 years of age, weighting 134.5 lb, was diagnosed with procedural pain and was treated with VOLTAREN. After drug was administered, patient experienced the following problems/side effects: anal haemorrhage, rectal discharge, rectal perforation, . VOLTAREN dosage: 50 MG, QD. Patient was hospitalized. Patient recovered.