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Orlistat Side Effects Report #5612379-3
Consumer or non-health professional from UNITED KINGDOM reported ORLISTAT problem on Jan 22, 2008. Male patient, 67 years of age, weighting 210.1 lb, was diagnosed with obesity and was treated with ORLISTAT. After drug was administered, patient experienced the following problems/side effects: toe amputation, . ORLISTAT dosage: unknown. Patient was hospitalized. Patient recovered.

Humalog Side Effects Report #5631057-8
HUMALOG problem was reported by a Consumer or non-health professional from TURKEY on Feb 06, 2008. Female patient, 40 years of age, weighting 187.4 lb, was diagnosed with hypertension and was treated with HUMALOG. After drug was administered, patient experienced the following problems/side effects: toe amputation, weight increased, . HUMALOG dosage: unknown. During the same period patient was treated with DIAMICRON, NEURONTIN, LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Avastin Side Effects Report #5606823-5
Health Professional from UNITED KINGDOM reported AVASTIN problem on Jan 14, 2008. Female patient, 58 years of age, was diagnosed with glaucoma and was treated with AVASTIN. After drug was administered, patient experienced the following problems/side effects: toe amputation, . AVASTIN dosage: 2.5 MG, UNK. Patient recovered.

Humira Side Effects Report #5575217-3
HUMIRA problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Dec 17, 2007. Female patient, weighting 112.4 lb, was diagnosed with rheumatoid arthritis and was treated with HUMIRA. After drug was administered, patient experienced the following problems/side effects: toe amputation, . HUMIRA dosage: unknown. During the same period patient was treated with PREDNISOLONE, NIFEDIPINE, ATENOLOL, BENDROFLUMETHIAZIDE, CALCIUM CARBONATE, HYPROMELLOSE, LANSOPRAZOLE, NABUMETONE. Patient was hospitalized. Patient recovered.


Humulin Side Effects Report #5514850-1
Consumer or non-health professional from TURKEY reported HUMULIN N problem on Nov 05, 2007. Male patient, weighting 94.80 lb, was treated with HUMULIN N. After drug was administered, patient experienced the following problems/side effects: toe amputation, . HUMULIN N dosage: unknown. During the same period patient was treated with HUMULIN R, HUMULIN R, HUMULIN R. Patient was hospitalized. Patient recovered.

Cyclosporine Side Effects Report #5346891-1
CYCLOSPORINE problem was reported by a Consumer or non-health professional from UNITED STATES on May 29, 2007. Female patient was diagnosed with immunosuppression, antiviral prophylaxis and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: toe amputation, . CYCLOSPORINE dosage: MEAN DOSE 186.7 MG (DIVIDED DOSING). During the same period patient was treated with ACYCLOVIR OR GANCICLOVIR, MYCOPHENOLATE MOFETIL, PREDNISONE. Patient recovered.

Humulin Side Effects Report #5620351-2
Consumer or non-health professional from TURKEY reported HUMULIN problem on Jan 28, 2008. Female patient, weighting 176.4 lb, was diagnosed with type 2 diabetes mellitus and was treated with HUMULIN. After drug was administered, patient experienced the following problems/side effects: foot amputation, toe amputation, . HUMULIN dosage: unknown. During the same period patient was treated with LANTUS. Patient recovered.

Seroquel Side Effects Report #5601450-8
SEROQUEL problem was reported by a Health Professional from UNITED STATES on Jan 15, 2008. Male patient, 48 years of age, weighting 370.8 lb, was diagnosed with depression and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, toe amputation, . SEROQUEL dosage: unknown. During the same period patient was treated with HALDOL, ZYPREXA, ATIVAN, BENADRYL. Patient recovered.

Avastin Side Effects Report #5606866-1
Health Professional from UNITED KINGDOM reported AVASTIN problem on Jan 14, 2008. Female patient, 41 years of age, was diagnosed with glaucoma and was treated with AVASTIN. After drug was administered, patient experienced the following problems/side effects: off label use, toe amputation, . AVASTIN dosage: 2.5 MG, UNK. Patient recovered.


Leuprolide Side Effects Report #5499323-7
LEUPROLIDE ACETATE problem was reported by a Consumer or non-health professional from NEW ZEALAND on Oct 22, 2007. Male patient, 71 years of age, was diagnosed with prostate cancer and was treated with LEUPROLIDE ACETATE. After drug was administered, patient experienced the following problems/side effects: peripheral ischaemia, toe amputation, . LEUPROLIDE ACETATE dosage: 22.5 MG (22.5 MG, 1 IN 3 M). During the same period patient was treated with ZOLEDRONIC ACID, ALLPURINOL, OMEPRAZOLE, ATENOLOL, BUDESONIDE. Patient was hospitalized. Patient recovered.

Leuprolide Side Effects Report #5422940-7
Consumer or non-health professional from NEW ZEALAND reported LEUPROLIDE ACETATE problem on Aug 15, 2007. Male patient, 71 years of age, was diagnosed with prostate cancer and was treated with LEUPROLIDE ACETATE. After drug was administered, patient experienced the following problems/side effects: peripheral ischaemia, toe amputation, . LEUPROLIDE ACETATE dosage: 22.5 MG (22.5 MG, 1 IN 3 M) INJECTION. During the same period patient was treated with ZOLEDRONIC ACID, ALLOPURINOL, OMEPRAZOLE, ATENOLOL, BUDESONIDE. Patient was hospitalized. Patient recovered.

Cyclosporine Side Effects Report #5377266-7
CYCLOSPORINE problem was reported by a Consumer or non-health professional from UNITED STATES on June 22, 2007. Male patient, 63 years of age, was diagnosed with renal transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: skin ulcer, toe amputation, . CYCLOSPORINE dosage: 100 MG, QD. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Viagra Side Effects Report #5398207-2
Consumer or non-health professional from BRAZIL reported VIAGRA problem on July 16, 2007. Male patient, weighting 202.8 lb, was diagnosed with erectile dysfunction and was treated with VIAGRA. After drug was administered, patient experienced the following problems/side effects: arrhythmia, toe amputation, . VIAGRA dosage: unknown. During the same period patient was treated with CAPTOPRIL, INSULIN. Patient recovered.

Cyclosporine Side Effects Report #5377266-7
CYCLOSPORINE problem was reported by a Consumer or non-health professional from UNITED STATES on June 22, 2007. Male patient, 63 years of age, was diagnosed with renal transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: skin ulcer, toe amputation, . CYCLOSPORINE dosage: 100 MG, QD. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.


Viagra Side Effects Report #5398207-2
Consumer or non-health professional from BRAZIL reported VIAGRA problem on July 16, 2007. Male patient, weighting 202.8 lb, was diagnosed with erectile dysfunction and was treated with VIAGRA. After drug was administered, patient experienced the following problems/side effects: arrhythmia, toe amputation, . VIAGRA dosage: unknown. During the same period patient was treated with CAPTOPRIL, INSULIN. Patient recovered.

Alprostadil Side Effects Report #5797889-0
ALPROSTADIL problem was reported by a Consumer or non-health professional from GERMANY on June 13, 2008. Male patient, 72 years of age, was diagnosed with arterial occlusive disease and was treated with ALPROSTADIL. After drug was administered, patient experienced the following problems/side effects: condition aggravated, toe amputation, . ALPROSTADIL dosage: unknown. Patient recovered.

Zemplar Side Effects Report #5737683-X
Physician from GERMANY reported ZEMPLAR problem on Mar 19, 2008. Female patient, weighting 154.3 lb, was diagnosed with hyperparathyroidism secondary and was treated with ZEMPLAR. After drug was administered, patient experienced the following problems/side effects: coronary artery bypass, toe amputation, . ZEMPLAR dosage: unknown. During the same period patient was treated with SEVELAMER HYDROCHLORIDE, ALFACALCIDOL, AQUAPHOR, TORSEMIDE, FOSINOPRIL, METOPROLOL SUCCINATE, DREISAVIT. Patient was hospitalized. Patient recovered.

Zemplar Side Effects Report #5738200-0
ZEMPLAR problem was reported by a Physician from GERMANY on May 13, 2008. Female patient, weighting 154.3 lb, was diagnosed with hyperparathyroidism secondary and was treated with ZEMPLAR. After drug was administered, patient experienced the following problems/side effects: coronary artery bypass, toe amputation, . ZEMPLAR dosage: unknown. During the same period patient was treated with SEVELAMER HYDROCHLORIDE, ALFACALCIDOL, AQUAPHOR, TORSEMIDE, FOSINOPRIL, METOPROLOL SUCCINATE, DREISAVIT. Patient was hospitalized. Patient recovered.

Chantix Side Effects Report #5744030-6
Health Professional from UNITED STATES reported CHANTIX problem on May 16, 2008. Male patient, weighting 140.0 lb, was treated with CHANTIX. After drug was administered, patient experienced the following problems/side effects: skin ulcer, toe amputation, . CHANTIX dosage: unknown. Patient recovered.


Humalog Side Effects Report #5706872-2
HUMALOG problem was reported by a Consumer or non-health professional from TURKEY on Apr 02, 2008. Male patient, 72 years of age, weighting 198.4 lb, was diagnosed with diabetes mellitus and was treated with HUMALOG. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, toe amputation, weight increased, . HUMALOG dosage: unknown. Patient was hospitalized. Patient recovered.

Humulin Side Effects Report #5706875-8
Consumer or non-health professional from TURKEY reported HUMULIN R problem on Apr 02, 2008. Female patient, weighting 202.8 lb, was diagnosed with hypertension, diabetes mellitus and was treated with HUMULIN R. After drug was administered, patient experienced the following problems/side effects: blood glucose increased, toe amputation, wound, . HUMULIN R dosage: unknown. During the same period patient was treated with DIOVAN HCT, METFORMIN HYDROCHLORIDE, PAROL. Patient was hospitalized and became disabled. Patient recovered.

Humulin Side Effects Report #5333827-2
HUMULIN problem was reported by a Consumer or non-health professional from UNITED STATES on May 17, 2007. Female patient, 78 years of age, was diagnosed with diabetes mellitus and was treated with HUMULIN. After drug was administered, patient experienced the following problems/side effects: blood glucose decreased, toe amputation, . HUMULIN dosage: unknown. During the same period patient was treated with ACTOS, NOVOLOG. Patient was hospitalized. Patient recovered.

Avonex Side Effects Report #5316386-X
Consumer or non-health professional from UNITED STATES reported AVONEX problem on Apr 17, 2007. Male patient, 52 years of age, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: localised infection, toe amputation, vein disorder, . AVONEX dosage: unknown. Patient was hospitalized. Patient recovered.

Seroquel Side Effects Report #5262138-9
SEROQUEL problem was reported by a Health Professional from UNITED STATES on Feb 28, 2007. Male patient, 48 years of age, weighting 370.8 lb, was diagnosed with depression and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, toe amputation, . SEROQUEL dosage: unknown. During the same period patient was treated with HALDOL, ZYPREXA. Patient recovered.

Erbitux Side Effects Report #5284322-0
Health Professional from UNITED STATES reported ERBITUX problem on Mar 30, 2007. Male patient, weighting 221.0 lb, was diagnosed with lung neoplasm malignant and was treated with ERBITUX. After drug was administered, patient experienced the following problems/side effects: gangrene, toe amputation, . ERBITUX dosage: 540MG WEEKLY IV. Patient was hospitalized. Patient recovered.

Humulin Side Effects Report #5623504-2
HUMULIN N problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 01, 2008. Female patient was treated with HUMULIN N. After drug was administered, patient experienced the following problems/side effects: pain, skin discolouration, toe amputation, . HUMULIN N dosage: unknown. Patient recovered.

Lantus Side Effects Report #5513005-4
Consumer or non-health professional from UNITED STATES reported LANTUS problem on Nov 03, 2007. Male patient, 48 years of age, was treated with LANTUS. After drug was administered, patient experienced the following problems/side effects: gangrene, staphylococcal infection, toe amputation, . LANTUS dosage: unknown. During the same period patient was treated with LEXAPRO, RISPERDAL, GLUCOPHAGE, ANTITHROMBOTIC AGENTS. Patient recovered.

Panafil Side Effects Report #5517800-7
PANAFIL problem was reported by a Consumer or non-health professional from UNITED STATES on Oct 29, 2007. Male patient, 82 years of age, weighting 177.9 lb, was diagnosed with diabetic ulcer and was treated with PANAFIL. After drug was administered, patient experienced the following problems/side effects: cellulitis, toe amputation, . PANAFIL dosage: unknown. During the same period patient was treated with INSULIN, METFORMIN, PAROXETINE, LISINOPRIL, GABAPENTIN, FLOMAX, NITROSTAT. Patient was hospitalized. Patient recovered.

Humalog Side Effects Report #5527765-X
Consumer or non-health professional from TURKEY reported HUMALOG problem on Nov 13, 2007. Female patient was diagnosed with type 2 diabetes mellitus and was treated with HUMALOG. After drug was administered, patient experienced the following problems/side effects: blood glucose decreased, oedema peripheral, toe amputation, treatment noncompliance, weight increased, . HUMALOG dosage: unknown. During the same period patient was treated with LANTUS, GLUKOFEN. Patient was hospitalized. Patient recovered.

Seroquel Side Effects Report #5394493-3
SEROQUEL problem was reported by a Health Professional from UNITED STATES on July 16, 2007. Male patient, weighting 220.5 lb, was diagnosed with schizoaffective disorder and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, leg amputation, toe amputation, . SEROQUEL dosage: unknown. During the same period patient was treated with RISPERDAL, ABILIFY. Patient was hospitalized. Patient recovered.

Cyclosporine Side Effects Report #5396203-2
Physician from UNITED STATES reported CYCLOSPORINE problem on July 18, 2007. Male patient, 63 years of age, was diagnosed with renal transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: osteomyelitis, skin ulcer, toe amputation, . CYCLOSPORINE dosage: 100 MG, QD. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5398228-X
METHOTREXATE problem was reported by a Consumer or non-health professional from on July 19, 2007. Male patient, 50 years of age, was diagnosed with psoriasis, hypertension, hypothyroidism, depression and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: osteomyelitis, skin cancer, toe amputation, . METHOTREXATE dosage: 15 MG WEEKLY. During the same period patient was treated with INFLIXIMAB, CYCLOSPORINE, FLUOCINONIDE, CLOBETASOL PROPIONATE, AMLODIPINE, LEVOTHYROXINE, VENLAFAXINE. Patient was hospitalized. Patient recovered.

Seroquel Side Effects Report #5394493-3
Health Professional from UNITED STATES reported SEROQUEL problem on July 16, 2007. Male patient, weighting 220.5 lb, was diagnosed with schizoaffective disorder and was treated with SEROQUEL. After drug was administered, patient experienced the following problems/side effects: diabetes mellitus, leg amputation, toe amputation, . SEROQUEL dosage: unknown. During the same period patient was treated with RISPERDAL, ABILIFY. Patient was hospitalized. Patient recovered.

Cyclosporine Side Effects Report #5396203-2
CYCLOSPORINE problem was reported by a Physician from UNITED STATES on July 18, 2007. Male patient, 63 years of age, was diagnosed with renal transplant and was treated with CYCLOSPORINE. After drug was administered, patient experienced the following problems/side effects: osteomyelitis, skin ulcer, toe amputation, . CYCLOSPORINE dosage: 100 MG, QD. During the same period patient was treated with MYCOPHENOLATE MOFETIL, PREDNISONE. Patient was hospitalized. Patient recovered.

Methotrexate Side Effects Report #5398228-X
Consumer or non-health professional from reported METHOTREXATE problem on July 19, 2007. Male patient, 50 years of age, was diagnosed with psoriasis, hypertension, hypothyroidism, depression and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: osteomyelitis, skin cancer, toe amputation, . METHOTREXATE dosage: 15 MG WEEKLY. During the same period patient was treated with INFLIXIMAB, CYCLOSPORINE, FLUOCINONIDE, CLOBETASOL PROPIONATE, AMLODIPINE, LEVOTHYROXINE, VENLAFAXINE. Patient was hospitalized. Patient recovered.

Avonex Side Effects Report #5712971-1
AVONEX problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 09, 2008. Male patient, 60 years of age, was diagnosed with multiple sclerosis and was treated with AVONEX. After drug was administered, patient experienced the following problems/side effects: amputation revision, cellulitis, toe amputation, . AVONEX dosage: unknown. Patient was hospitalized. Patient recovered.