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What symptoms can Tacrolimus cause?

Tacrolimus Safety Information and Side Effects

Tacrolimus Safety Information

Death ( 158 reports)    ➢ More

Pulmonary Embolism, Hypotension, Post Procedural Haemorrhage

This case suggests a potential Tacrolimus Sustained-release Capsules Death side effect(s) that can have serious consequences. A 49-year-old patient from CN (weight:NA) was diagnosed with the following health condition(s): prophylaxis against transplant rejection and used Tacrolimus Sustained-release Capsules (dosage: NA) starting Dec 14, 2013. Soon after starting Tacrolimus Sustained-release Capsules the patient began experiencing various side effects, including:
  • Pulmonary Embolism
  • Hypotension
  • Post Procedural Haemorrhage
Drugs used concurrently:
  • Atg-fresenius S (500 Mg, Uid/qd)
  • Methylprednisolone (1000 Mg, Uid/qd)
  • Methylprednisolone (500 Mg, Uid/qd)
  • Insulin Aspart (Unk)
  • Although Tacrolimus Sustained-release Capsules demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Death, may still occur.

    Off Label Use ( 158 reports)    ➢ More

    Off Label Use, Epilepsy, Syncope

    Adverse event was reported on Mar 03, 2014 by a male taking Tacrolimus Ointment (Dosage: 0.1 %, Once A Day, Twice Weekly) was diagnosed with and. Location: NL , child 9. years of age, Directly after treatment started, patient experienced the unwanted or unexpected Tacrolimus side effects: off label use, epilepsy, syncope.

    Blood Creatinine Increased ( 139 reports)    ➢ More

    Exposure During Pregnancy, Transplant Rejection, Blood Creatinine Increased, Anaemia, Hypertension, Foetal Growth Restriction, C-reactive Protein Increased, Haemorrhage, Retained Placenta Or Membranes

    This Blood Creatinine Increased problem was reported by a consumer or non-health professional from SE. A 28-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): immunosuppression.On NS a consumer started treatment with Tacrolimus Systemic (dosage: Unk). The following health products were being taken at the same time:
  • Mycophenolate Mofetil (Unk)
  • Prednisolone (Unk)
  • Azathioprine (Unk)
  • Vitamin D /00107901/ (Unk)
  • Folic Acid (Unk)
  • Vitamin B12 /00056201/ (Unk)
  • Zinc (Unk)
  • When commencing Tacrolimus Systemic, the patient experienced the following unwanted symptoms /side effects:
    • Exposure During Pregnancy
    • Transplant Rejection
    • Blood Creatinine Increased
    • Anaemia
    • Hypertension
    • Foetal Growth Restriction
    • C-reactive Protein Increased
    • Haemorrhage
    • Retained Placenta Or Membranes
    Although all health products are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Blood Creatinine Increased, may become evident only after a product is in use by the general population.

    Diarrhoea ( 126 reports)    ➢ More

    Off Label Use, Hepatic Failure, Chronic Graft Versus Host Disease, Nerve Compression, Polyneuropathy, Gastrointestinal Haemorrhage, Diarrhoea

    A case of a 51-year-old patient (weight: NA) from DE was presented. The patient developed the following symptoms/conditions: chronic graft versus host disease,immunosuppression and was treated with Tacrolimus Systemic (dosage: Unk) starting NS. Concurrently used drugs:
  • Prednisolone (Unk)
  • Prednisolone
  • Mycophenolate Mofetil (Unk)
  • Rituximab (Unk)
  • Soon after that, the subject experienced the following of symptoms:
    • Off Label Use
    • Hepatic Failure
    • Chronic Graft Versus Host Disease
    • Nerve Compression
    • Polyneuropathy
    • Gastrointestinal Haemorrhage
    • Diarrhoea
    This opens a possibility that Tacrolimus Systemic could cause Diarrhoea and that some subjects may be more susceptible.

    Pyrexia ( 122 reports)    ➢ More

    Pyrexia, Vomiting, Abdominal Pain

    on Mar 11, 2014 a male from GB , 16 years of age, weighting 110.2 lb, was diagnosed with and was treated with Tacrolimus Mr4 Capsules. Directly after treatment started, patient experienced the unwanted or unexpected Tacrolimus side effects: pyrexia, vomiting, abdominal pain. Tacrolimus Mr4 Capsules dosage: 4 Mg, Uid/qd.
    Associated medications used:
    • Prednisolone (5 Mg, Uid/qd)
    • Magnesium (4 Mmol, Monthly)
    • Mycophenolate (500 Mg, Bid)
    • Gentamicin (Unk)
    • Cefotaxime (Unk)
    • Amoxicillin (250 Mg, Tid)
    • Paracetamol (Unk)
    • Paracetamol
    The patient was hospitalized.

    Common Tacrolimus Side Effects

    Click to view detailed reports:

    Death (158)
    Off Label Use (158)
    Blood Creatinine Increased (139)
    Diarrhoea (126)
    Pyrexia (122)
    Renal Impairment (116)
    Pneumonia (111)
    Condition Aggravated (103)
    Cytomegalovirus Infection (91)
    Renal Failure Acute (81)
    Transplant Rejection (77)
    Abdominal Pain (74)
    Thrombotic Microangiopathy (69)
    Convulsion (68)
    Hypertension (68)
    Vomiting (66)
    Renal Failure (65)
    Sepsis (64)
    Graft Versus Host Disease (59)
    Nausea (59)
    Anaemia (58)
    Respiratory Failure (57)
    Multi-organ Failure (57)
    Interstitial Lung Disease (56)
    Complications Of Transplanted Kidney (53)
    Tremor (53)
    Kidney Transplant Rejection (52)
    Headache (51)
    Dyspnoea (49)
    Urinary Tract Infection (48)
    Hyperglycaemia (47)
    Confusional State (44)
    Dehydration (44)
    Diabetes Mellitus (44)
    Septic Shock (43)
    Haemodialysis (42)
    Neurotoxicity (41)
    Aspartate Aminotransferase Increased (41)
    Toxicity To Various Agents (40)
    Thrombocytopenia (40)
    Pancytopenia (40)
    Alanine Aminotransferase Increased (40)
    Posterior Reversible Encephalopathy Syndrome (40)
    Platelet Count Decreased (39)
    Liver Transplant Rejection (39)
    Asthma (38)
    Cardiac Arrest (37)
    Haemoglobin Decreased (37)
    Blood Urea Increased (36)
    Asthenia (35)

    ➢ More

    Have you considered participating in a Tacrolimus Clinical Research Study or a Tacrolimus Clinical Trial? Check latest here

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    Tacrolimus Forum

    Did You Have a Tacrolimus Side Effect?

    Yes, Severe
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    How Effective is Tacrolimus for You?

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