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Trazodone Depression Side Effects

Trazodone Depression Side Effect Reports


The following Trazodone Depression side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Depression, can occur, and what you can do about them.

A side effect could appear soon after you start Trazodone or it might take time to develop.



Uterine Perforation, Ectopic Pregnancy With Contraceptive Device, Ruptured Ectopic Pregnancy, Depression, Anxiety, Fear Of Pregnancy, Injury

This Depression side effect was reported by a consumer or non-health professional from US. A 21-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Trazodone (dosage: Unk), which was started on Apr 04, 2006. Concurrently used drugs:
  • Lorazepam (Unk)
  • Mirena (20 Mcg/24hr, Cont)
  • Percocet
  • Ibuprofen
When starting to take Trazodone the consumer reported the following symptoms:
  • Uterine Perforation
  • Ectopic Pregnancy With Contraceptive Device
  • Ruptured Ectopic Pregnancy
  • Depression
  • Anxiety
  • Fear Of Pregnancy
  • Injury
The patient was hospitalized. These side effects may potentially be related to Trazodone.
Anger, Nervousness, Mania, Depression

This Depression Trazodone side effect was reported by a consumer or non-health professional from US on Jan 03, 2013. A Female , 44 years of age, weighting 210.0 lb, was diagnosed with and was treated with Trazodone. The patient presented the following health conditions:
  • Anger
  • Nervousness
  • Mania
  • Depression
. Trazodone dosage: NA. Additional drugs used at the same time:
  • Ziprasidone
  • Ziprasidone
Lethargy, Mental Impairment, Overdose, Depression, Confusional State

This is a Trazodone Hcl side effect report of a 52-year-old female patient (weight:NA) from UNITED STATES, suffering from the following symptoms/conditions: NA, who was treated with Trazodone Hcl (dosage:NA, start time: Jan 01, 2009), combined with:
  • Lexapro
  • Clonazepam
  • Vyvanse (80 Mg, 1x/day:qd ; 80 Mg, 1x/day:gd (two 40 Mg Capsules), Oral)
  • Lamictal
  • Zegerid /00661201/ (omeprazole)
, and developed a serious reaction and a Depression side effect. The patient presented with:
  • Lethargy
  • Mental Impairment
  • Overdose
  • Depression
  • Confusional State
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Trazodone Hcl treatment in female patients suffering from NA, resulting in Depression.

Malaise, Off Label Use, Depression, Irritability, Insomnia

A 54-year-old patient (weight: NA) from UNITED STATES with the following symptoms: NA started Trazodone Hcl treatment (dosage: NA) on Jan 01, 2006. Soon after starting Trazodone Hcl treatment, the consumer experienced several side effects, including:
  • Malaise
  • Off Label Use
  • Depression
  • Irritability
  • Insomnia
. Concurrently used drugs:
  • Seroquel
  • Seroquel
  • Seroquel
This finding indicates that some patients can be more vulnerable to developing Trazodone Hcl side effects, such as Depression.
Depression, Agitation, Hallucination, Auditory, Mental Disorder

A female patient from UNITED KINGDOM was prescribed and started Trazodone Hcl on May 25, 2012. Patient felt the following Trazodone side effects: depression, agitation, hallucination, auditory, mental disorder Additional patient health information: Female , 44 years of age, The consumer reported the following symptoms: . Trazodone Hcl dosage: Unk. Concurrently used drugs:
  • Betaseron (Unk)
Mental Disorder, Agitation, Hallucination, Auditory, Depression

This report suggests a potential Trazodone Hcl Depression side effect(s) that can have serious consequences. A 44-year-old female patient from UNITED KINGDOM (weight:NA) was diagnosed with the following health condition(s): NA and used Trazodone Hcl (dosage: Unk) starting May 11, 2012. Soon after starting Trazodone Hcl the patient began experiencing various side effects, including:
  • Mental Disorder
  • Agitation
  • Hallucination, Auditory
  • Depression
Drugs used concurrently:
  • Betaseron (Unk)
Although Trazodone Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Depression, may still occur.
Psychotic Disorder, Aggression, Suicidal Ideation, Depression

An adverse event was reported by a health professional on Aug 05, 2011 by a Female taking Trazodone Hcl (dosage: NA) . Location: UNITED STATES , weighting 225.2 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Trazodone side effects: psychotic disorder, aggression, suicidal ideation, depression. Additional medications/treatments:
Associated medications used:
  • Advair Diskus 100/50
  • Lorazepam
  • Singulair
  • Effexor Xr
  • Nuvigil
  • Nuvigil (250 Milligram;)
  • Avonex
  • Topamax
Irritability, Blood Creatinine Increased, Emotional Disorder, Urinary Hesitation, Renal Impairment, Osteoporosis, Depression

This Depression problem was reported by a consumer or non-health professional from UNITED STATES. A female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Apr 01, 2009 a consumer started treatment with Trazodone (dosage: Unk). The following drugs/medications were being taken at the same time:
  • Levothyroxine (Unk)
  • Effexor Xr (300 Mg, 1x/day)
  • Pristiq (100 Mg, 1x/day)
  • Klonopin (Unk, As Needed)
  • Effexor (Unk)
  • Effexor Xr
  • Pristiq (50 Mg, 1x/day)
When commencing Trazodone, the patient experienced the following unwanted symptoms /side effects:
  • Irritability
  • Blood Creatinine Increased
  • Emotional Disorder
  • Urinary Hesitation
  • Renal Impairment
  • Osteoporosis
  • Depression
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Depression, may become evident only after a product is in use by the general population.
Depression, Anxiety, Malaise, Panic Attack, Adverse Event

This is a Trazodone Hcl side effect report of a 45-year-old female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Trazodone Hcl (dosage: NA) starting NS. Concurrently used drugs:
  • Seroquel
  • Seroquel
Soon after that, the consumer experienced the following of symptoms:
  • Depression
  • Anxiety
  • Malaise
  • Panic Attack
  • Adverse Event
The patient was hospitalized. This opens a possibility that Trazodone Hcl could cause Depression and that some female patients may be more susceptible.
Erectile Dysfunction, Erection Increased, Depression

This Depression side effect was reported by a consumer or non-health professional from UNITED STATES on Oct 06, 2011. A patient from UNITED STATES , 24 years of age, was diagnosed with and was treated with Trazodone Hcl. Directly after treatment started, patient experienced the unwanted or unexpected Trazodone side effects: erectile dysfunction, erection increased, depression. Trazodone Hcl dosage: (50 Mg). The patient was hospitalized. These side effects may potentially be related to Trazodone Hcl.
Irritability, Agitation, Depression, Back Pain, Feeling Abnormal, Blood Pressure Increased

This Depression side effect was reported by a consumer or non-health professional from UNITED STATES. A 46-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Trazodone Hcl (dosage: NA), which was started on Jan 01, 2010. Concurrently used drugs:
  • Lisinopril W/hydrochlorothiazide (prinzide /00977901/)
  • Risperidone (91 Dosage Forms, 1 D), Oral)
  • Risperidone (91 Dosage Forms, 1 D), Oral)
  • Risperidone (91 Dosage Forms, 1 D), Oral)
  • Metformin Hcl
  • Ativan
  • Celexa
  • Neurontin (1200 Mg (400 Mg, 3 In 1 D))
When starting to take Trazodone Hcl the consumer reported the following symptoms:
  • Irritability
  • Agitation
  • Depression
  • Back Pain
  • Feeling Abnormal
  • Blood Pressure Increased
These side effects may potentially be related to Trazodone Hcl.
Suicide Attempt, Abnormal Behaviour, Unresponsive To Stimuli, Cataplexy, Depression, Condition Aggravated, Bipolar Disorder, Sleep-related Eating Disorder

This Depression Trazodone Hcl side effect was reported by a physician from UNITED STATES on Jan 19, 2012. A male , 45 years of age, weighting 210.0 lb, was diagnosed with and was treated with Trazodone Hcl. The patient presented the following health conditions:
  • Suicide Attempt
  • Abnormal Behaviour
  • Unresponsive To Stimuli
  • Cataplexy
  • Depression
  • Condition Aggravated
  • Bipolar Disorder
  • Sleep-related Eating Disorder
. Trazodone Hcl dosage: NA. Additional drugs used at the same time:
  • Fluoxetine Hydrochloride
  • Xyrem (See Image: Oral)
  • Xyrem (See Image: Oral)
  • Xyrem (See Image: Oral)
  • Xyrem (See Image: Oral)
  • Xyrem (See Image: Oral)
  • Zolpidem Tartrate
  • Omeprazole
The patient was hospitalized.
Delirium, Metabolic Encephalopathy, Depression, Suicide Attempt, Blood Creatinine Decreased, Ataxia, Weight Increased, Condition Aggravated

This is a Trazodone Hydrochloride side effect report of a 72-year-old patient (weight:NA) from SWITZERLAND, suffering from the following symptoms/conditions: depression, who was treated with Trazodone Hydrochloride (dosage:300 Mg Daily, Oral, start time: NS), combined with:
  • Bupropion Hcl (300 Mg Daily, Oral)
  • Lithium Carbonate (Oral)
, and developed a serious reaction and a Depression side effect. The patient presented with:
  • Delirium
  • Metabolic Encephalopathy
  • Depression
  • Suicide Attempt
  • Blood Creatinine Decreased
  • Ataxia
  • Weight Increased
  • Condition Aggravated
which developed after the beginning of treatment. The patient was hospitalized and became disabled. This side effect report can indicate a possible existence of increased vulnerability to Trazodone Hydrochloride treatment in patients suffering from depression, resulting in Depression.
Suicidal Ideation, Depression, Suicide Attempt, Mental Disorder, Activities Of Daily Living Impaired

A female patient (weight: NA) from UNITED STATES with the following symptoms: NA started Trazodone treatment (dosage: Unk) on NS. Soon after starting Trazodone treatment, the consumer experienced several side effects, including:
  • Suicidal Ideation
  • Depression
  • Suicide Attempt
  • Mental Disorder
  • Activities Of Daily Living Impaired
. Concurrently used drugs:
  • Methylphenidate (Unk)
  • Lorazepam (5 Mg, 1x/day)
  • Lamotrigine (Unk)
  • Zolpidem (Unk)
  • Geodon (160 Mg, 1x/day)
This finding indicates that some patients can be more vulnerable to developing Trazodone side effects, such as Depression.
Vomiting, Joint Stiffness, Suicidal Ideation, Depression, Dependence

A female patient from UNITED STATES was prescribed and started Trazodone Hcl on Jan 12, 2012. After Trazodone was administered, patient encountered several Trazodone side effects: vomiting, joint stiffness, suicidal ideation, depression, dependence Additional patient health information: Female , weighting 165.0 lb, The consumer reported the following symptoms: was diagnosed with and. Trazodone Hcl dosage: NA. Concurrently used drugs:
  • Alprazolam
  • Adderall 5
Multiple Sclerosis Relapse, Depression, Memory Impairment, Blood Glucose Increased, Progressive Multifocal Leukoencephalopathy, Weight Decreased

This report suggests a potential Trazodone Hcl Depression side effect(s) that can have serious consequences. A 37-year-old female patient from UNITED STATES (weight:NA) was diagnosed with the following health condition(s): NA and used Trazodone Hcl (dosage: NA) starting Aug 06, 2008. Soon after starting Trazodone Hcl the patient began experiencing various side effects, including:
  • Multiple Sclerosis Relapse
  • Depression
  • Memory Impairment
  • Blood Glucose Increased
  • Progressive Multifocal Leukoencephalopathy
  • Weight Decreased
Drugs used concurrently:
  • Cymbalta
  • Acetaminophen
  • Acetaminophen
  • Seroquel
  • Methylphenidate
  • Hydrocodone Bitartrate
  • Tizanidine Hcl
  • Seroquel
Although Trazodone Hcl demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Depression, may still occur.
Suicidal Ideation, Depression, Weight Decreased

An adverse event was reported by a physician on Jan 06, 2012 by a Female taking Trazodone (dosage: 20 Mg, 1x/day At Bedtime) was diagnosed with and. Location: CANADA , 45 years of age, patient began experiencing various side effects, including: Patient felt the following Trazodone side effects: suicidal ideation, depression, weight decreased. Additional medications/treatments:
Multiple prescriptions taken:
  • Lyrica (50 Mg, 1x/day)
  • Nexium (40 Mg, 1x/day)
  • Diane (Unk)
  • Cymbalta
  • Cymbalta (60 Mg, 1x/day)
  • Lyrica (25 Mg, 1x/day)
  • Flexeril (10 Mg, 1x/day As Needed)
  • Maxeran (Unk)
Hallucination, Depression, Insomnia, Irritability

This Depression problem was reported by a health professional from UNITED STATES. A 12-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Nov 27, 2011 a consumer started treatment with Trazodone Hcl (dosage: NA). The following drugs/medications were being taken at the same time:
  • Zoloft (25mg)
  • Zoloft (50mg)
When commencing Trazodone Hcl, the patient experienced the following unwanted symptoms /side effects:
  • Hallucination
  • Depression
  • Insomnia
  • Irritability
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Depression, may become evident only after a product is in use by the general population.
Application Site Erosion, Depression, Product Adhesion Issue, Withdrawal Syndrome, Product Quality Issue

This is a Trazodone Hydrochloride side effect report of a patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: sleep disorder,depression,pain,anxiety and was treated with Trazodone Hydrochloride (dosage: 10mg/100 Mg Daily) starting Jan 01, 2011. Concurrently used drugs:
  • Pristiq
  • Fentanyl-100 (Ndc#0781-7244)
  • Lorazepam
  • Methadone Hcl
  • Lisinopril And Hydrochlorothiazide (20/25 Mg Daily)
Soon after that, the consumer experienced the following of symptoms:
  • Application Site Erosion
  • Depression
  • Product Adhesion Issue
  • Withdrawal Syndrome
  • Product Quality Issue
This opens a possibility that Trazodone Hydrochloride could cause Depression and that some patients may be more susceptible.
Anorgasmia, Economic Problem, Frustration, Depression, Urinary Incontinence, Condition Aggravated

This Depression side effect was reported by a consumer or non-health professional from UNITED STATES on Oct 13, 2011. A female patient from UNITED STATES , weighting 140.0 lb, was diagnosed with and was treated with Trazodone Hcl. Patient felt the following Trazodone side effects: anorgasmia, economic problem, frustration, depression, urinary incontinence, condition aggravated. Trazodone Hcl dosage: 100 Mg One Nightly.
Multiple prescriptions taken:
  • Zoloft (150 Mg Once Daily)
These side effects may potentially be related to Trazodone Hcl.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Trazodone Depression Causes and Reviews


Depression is a serious medical illness. It's more than just a feeling of being sad or "blue" for a few days. If you are one of the more than 19 million teens and adults in the United States who have Depression, the feelings do not go away. They persist and interfere with your everyday life. Symptoms can include

  • Feeling sad or "empty"
  • Loss of interest in favorite activities
  • Overeating, or not wanting to eat at all
  • Not being able to sleep, or sleeping too much
  • Feeling very tired
  • Feeling hopeless, irritable, anxious, or guilty
  • Aches or pains, headaches, cramps, or digestive problems
  • Thoughts of death or suicide

Depression is a disorder of the brain. There are a variety of causes, including genetic, biological, environmental, and psychological factors. Depression can happen at any age, but it often begins in teens and young adults. It is much more common in women. Women can also get postpartum Depression after the birth of a baby. Some people get seasonal affective disorder in the winter. Depression is one part of bipolar disorder.

There are effective treatments for Depression, including antidepressants, talk therapy, or both.

NIH: National Institute of Mental Health


Trazodone Depression Reviews

Sat, 07 Sep 2013

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Sun, 19 Jun 2011

I was walking through the wreckage of the north minneapolis tornado. I was worried about my middle daughter who hadn't picked up her phone when I called her to see if she was ok. The police said I would need to park my car and walk the rest of the way. I statred walking aafter a bit my neck to my R ear. I tried hard and couldn't straighten it. I was emotionally relieved to find there were no trees on her home(which my youngest daughter said there was. I started shaking once I got into the house and saw my middle daughter was alright. I also had been taking abilify. I'm also taking wellbutrin,lexapro and Trazodone. My psychiatrist said that the combination of anti-depressants could cause memory problems which I have been having.

Wed, 09 Nov 2011

I didn't even realize all the symptoms i was experiencing was from the wellbutrin until I stopped taking it and they all disappeared. I was on Wellbutrin XL 300mg, the generic for 6 months, and then switched to the brand name for about 4 months. I had some scary side effects the first two weeks, but most of those went away with time. After the initial 2 weeks, I suffered from a constant pressure headache that would NEVER go away no matter what I did or how many ibuprofen, tylenol, or naproxen I tried to take. I also had shaky hands and the occasional head twitch that I seemed to have no control over. I thought for a while I had some sort of neurological problem. My urine always smelled god awful and I would have to always spray the bathroom afterwards to cover the stench. I had trouble sleeping at night, insomnia and I even tried Trazodone and then Ambien after my doctor prescribed them. Neither one worked for me in the least bit. I was also slightly jittery, like I had just had a few cups of coffee. oh...and speaking of coffee, I had absolutely NO tolerance for coffee whatsoever. If I had a single sip of coffee, my heart started racing, my headache intensified, and I felt a strong sense of anxiety. It was the strangest thing. I didn't drink coffee for almost a year.
It wasn't until I quit Wellbutrin about 6 months ago, that I realized that all these things were caused by the Wellbutrin. I now can drink 2-3 cups of a coffee a day without any bad side effects, am headache free, my urine smells normal, and my hands no longer shake. Oh yes, and most important of all-I CAN SLEEP!!! YES!

Thu, 23 Apr 2009
can Trazodone hydrochloride cause steatosis of the liver or commonly called fatty liver diesise.
Thu, 05 May 2011
What are the common side effects of Venlafaxine; Trazodone
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Tramadol (5054)
Trazodone (1458)
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Top Trazodone Side Effects

Completed Suicide (190)
Priapism (134)
Insomnia (129)
Dizziness (118)
Nausea (113)
Depression (109)
Respiratory Arrest (108)
Pain (102)
Headache (101)
Vomiting (94)
Cardiac Arrest (94)
Fatigue (91)
Anxiety (89)
Dyspnoea (89)
Confusional State (88)
Serotonin Syndrome (86)
Overdose (86)
Diarrhoea (80)
Suicide Attempt (79)
Asthenia (68)
Suicidal Ideation (34)
Fall (33)
Somnolence (30)
Feeling Abnormal (30)
Convulsion (29)
Arthralgia (28)
Toxicity To Various Agents (28)
Malaise (28)
Pain In Extremity (28)
Rash (28)
Weight Increased (27)
Hypotension (27)
Gait Disturbance (26)
Product Quality Issue (26)
Intentional Overdose (26)
Myalgia (26)
Constipation (25)
Tremor (24)
Loss Of Consciousness (23)
Condition Aggravated (23)
Muscle Spasms (22)
Back Pain (22)
Cardio-respiratory Arrest (22)
Electrocardiogram Qt Prolonged (21)
Pyrexia (21)
Palpitations (21)
Hallucination (20)
Amnesia (20)
Erectile Dysfunction (19)
Paraesthesia (19)

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