Drug Side Effects Index: A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z


Insomnia from HPV (GARDASIL) 2009

Vaccine Manufacturer:MERCK & CO. INC.
Vaccine Code:HPV4
Vaccine Type:HUMAN PAPILLOVAVIRUS QUADRIVALENT
Vaccine Name:HPV (GARDASIL)
Year Reported:2009
Symptom Reported:Insomnia

HPV (GARDASIL) Side Effects Report #337591
HPV (GARDASIL) vaccine side effect was reported on 01/15/2009. Female patient, 13.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a physician concerning a 15 year old female with no previous medical, family, or social history who on 19-NOV-2007 was vaccinated with a first dose of GARDASIL IM. The patient's mother told the physician that a few weeks after the GARDASIL, the patient had body aches and generalized pain. The patient was seen by her pediatrician and a neurologist, and they both thought that it was from GARDASIL. The neurologist had diagnosed the patient with fibromyalgia. CPK was elevated. At the time of reporting, the patient was being treated with cyclobenzapine hydrochloride (MSD), melatonin, imipramine, and chiropractic therapy for the pain and insomnia. The patient has missed many days from school and volleyball because of the fibromyalgia. At the time of reporting, fibromyalgia persisted. The reporter considered fibromyalgia to be disabling. Additional information has been requested. 1/29/09-According to the general practitioner, fibromyalgia persisted while insomnia was being controlled on medication (not recovered).Onset Date: Approximately December 2007 (~a few weeks after Gardasil~, per pt's mother) 2/17/09-records received for DOS 7/23/08-neurology notes-C/O muscle aches and pains as well as sleep disturbance. Previously evaluated on 5/12/08, continues with pain on an almost daily basis. However no discomfort in past few days. Impression:history of severe pain in legs and arms and along cervical spine. Sleep disturbance resolved with use of Seroquel. No neurological cause of pain. No rheumatology consult at this time due to insurance issues." None"plasma creatine kinase, elevated 2/17/09-records received-MRI brain normal, MRI cervical spine minimal bulge at C5 to C6. Pseudotumor Chiari malformation and spinal instability ruled o ut. EMG and nerve conductions tudies normal. CPK sligh" . During the same period patient was treated with Unknown. Patient recovered.

HPV (GARDASIL) Side Effects Report #337792
HPV (GARDASIL) vaccine side effect was reported on 01/21/2009. Female patient, 25.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "extreme weakness, fatigue, dizziness, severe mood changes, anxiety, low grade fever, severe headaches, chills 1/30/09 Received PCP medical records of 1/22-1/30/2009. FINAL DX: Records reveal patient experienced weakness, dizziness, moody, decreased energy after HPV #1 & #2 given 7/10/2008 & 9/11/08. Increased fatigue, moody, nervous, heaviness in legs, sensitive to touch, generalized aching, low grade fever, chills after HPV#3 1/20/09. RTC 1/30 symptoms except dizziness persist & now w/tingling in back & arms. Difficulty sleeping. DTRs WNL. Dx w/rhinitis & possible early sinusitis. Tx w/nasal spray & given Rx for antibiotics if symptoms persist." none"allergy to Bactrum and Ceclor PMH: bronchitis, pneumonia. Hives. Family hx: arthtis, DM, HTN."LABS: WBC 13.1(H). ESR 4(N). . During the same period patient was treated with none. Patient recovered.

HPV (GARDASIL) Side Effects Report #339516
HPV (GARDASIL) vaccine side effect was reported on 02/12/2009. Female patient, 14.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "2/6/2009 7:00 p.m. To E.R. by ambulance for sudden onset altered loss of consciousness. Obtained labs, CT, lumbar puncture. Had been c/o insomnia over 3 weeks prior to event, but also documented in pt. record as having 'troubles getting to sleep at night' in 4/2008. 3/23/08 MR received for ER visit 2/6/08 with DX: Vomiting, unclear etiology. Altered LOC, unclear etiology. Pt presented with acute onset of vomiting with altered LOC. Pt recently reporting H/As and near syncopal episode. PE WNL. Given KCl for mild hypokalemia and d/c home for outpt f/u." none"scoliosis, headaches, muscle spasms in lumbar area. PMH: difficulty falling asleep 4/2008""CSF - neg. CBC - WNL UA - WNL, + for Tricyclics CT/head - no acute intracranial abnormality. Labs and Diagnostics: CBC WNL. Tox screen (-) for drugs of abuse. CT brain (-). K+ 3.1. BS 142. CSF WNL. CSF cx (-)." . During the same period patient was treated with 1. Amitriptyline 10 mg. 1 pill p.o. night before event. 2. Flexeril 10 mg. q8 hrs. prn back spasms.. Patient recovered.

HPV (GARDASIL) Side Effects Report #339960
HPV (GARDASIL) vaccine side effect was reported on 01/21/2009. Female patient, 24.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "One day after receiving injection patient had localized pain at site, aches, drowsy, muscle soreness especially in back down to middle lower back. C/o fever, some headaches, trouble sleeping and hard time getting going in the am." NoneNoneNone . Patient recovered.

HPV (GARDASIL) Side Effects Report #340451
HPV (GARDASIL) vaccine side effect was reported on 02/13/2009. Female patient, child 12.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a consumer concerning her daughter who on 18-Apr-2008 was vaccinated with the first 0.5ml dose of GARDASIL. After getting the first dose the patient experienced joint pain in back, hip and knees. On 16-Jul-2008 received the second dose of HPV vaccine and experienced fainting, dizziness, headache, trouble comprehending in school and joint pains. At the time of reporting the mother's patient stated that daughter still had headaches and dizziness. The patient sought unspecified medical attention. Additional information has been requested. 6/19/09 Medical records received DOS 4/4/08 to 5/08/09. Assessment: Insomnia, weight loss, otitis externa acute, depression with anxiety Patient became pale and c/o blurred vision, dizziness. Difficulty walking, lightheaded. Later otalgia, URI. Aching joints - hip, back, knee. Headache, abdominal pain, anxiety. Coughing, nose congestion with headaches, postnasal drip, sore throat. acute sinusitis, dyspnea. Hyperactivity. PTSD. ICD-9 Codes: 780.52, 783.21, 380.10, 300.4, 461.9 786.2 786.09, 784.0 789.07, 300.00, 995.20, 780.4, 388.70, V65.40, 465.9, V04.89" Unknown. 6/19/09 Medical records received DOS 4/4/08 to 5/08/09. Erythromycin allergy.Unknown. 6/19/09 Medical records received DOS 4/4/08 to 5/08/09. LABS and Diagnostics: Spirometry. CBC - WNL. TSH 1.220 ulU/ml. . During the same period patient was treated with Unknown. Patient recovered.

HPV (GARDASIL) Side Effects Report #340466
HPV (GARDASIL) vaccine side effect was reported on 02/13/2009. Female patient, child 12.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a physician concerning his 12 year old daughter with no known medical history and drug allergies, who on 22-JAN-2009 was vaccinated with a third dose of HPV vaccine at 15:00. Concomitant therapy included PREVACID. On 22-JAN-2009 the patient had a hard time falling sleep and woke up with a 102 degree fever and her legs were achy. The physician had given his daughter ADVIL liquid gels 400 mg for her symptoms. No laboratory studies were performed. The patient sought medical attention with her father. At the time of this report the patient had not recovered. Additional information has been requested." NoneNone . During the same period patient was treated with PREVACID. Patient recovered.

HPV (GARDASIL) Side Effects Report #340807
HPV (GARDASIL) vaccine side effect was reported on 02/26/2009. Female patient, 16.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "chronic debilitating headaches, chronic diahrrea, severe back & abdominal pain, tingling in hands and feet,numbness in hands & feet, stabbing pain in lower legs and feet, inability to stand, inability to walk, difficulty breathing, swollen lips, chest pain in conjunction with neck pain, loss of hair, chronic debilitating fatigue, nausea, vomiting, short term memory loss, inability to concentrate, stares off in the distance for long periods of time. These started right after the vaccination and continue to this day & have made her life as she knew it unmanageable. She can no longer attend school. Numerous trips to her pediatrician, blood tests, urine test, stool tests, emergency room visits, referred to neurologists, nutritionist. No one knows how to treat her. There is no treatment apparently. 3/16/09 Received consult records of 2/24/2009. FINAL DX: probable chronic fatigue syndrome, possibly exacerbated by recent EBV infection; reactive depression; likely vasovagal episodes; possible anxiety disorder. Records reveal patient experienced fatigue, nausea, numbness/tingling of hands/feet, HA, neck pain, intermittent diarrhea, chest pain w/SOB & heart pounding, intermittent difficulty walking, difficulty concentrating, decreased appetite, insomnia, apathy, moody, irritable. Approx 1 wk after initial HPV & Depoprovera injections, 11/12/08, developed waxing/waning fatigue which escalated to missing school in Dec & Jan. Suggested antidepressant & counseling. 3/9/09 Received PCP medical records of 2/2007-3/2/2009 included ER records of 2/9/2009. FINAL DX:none provided Records reveal patient experienced good health on 11/12, received depo-provera 1st dose along w/HPV #1. RTC 2/11 s/p ER visit 2/9 for chest pain, cough, runny nose, phlegm congestion. Parent reported back pain, hand tremors, leg pain, leg swelling, back pain, dizziness, joint stiffness, decreased concentration, fatigue, intermittent diarrhea, nausea since 11/08. Missed several days of school. Developed leg heaviness, gait disturbance," none"none PMH: acute pharyngitis, HA, acute sinusitis, cough, acne vulgaris tx w/minocin, abdominal pain, diarrhea. Family hx: depression, suicide.""ESR, ASO, FT4, TSH, ANA TITER, ANTI-DS-DNA, EBV AB PROFILE ACT WKST: FANA, STOOL, URINE, CARDIAC ENZYMES, EKG, CHEST X-RAY, CAT SCAN - NEURO TESTING IS NEXT WEEK. LABS 2/18/09: ASO 161(H). EBV IgG (+), nuclear antigen neg, IgM (+). ESR 3" . During the same period patient was treated with none. Patient recovered.

HPV (GARDASIL) Side Effects Report #341124
HPV (GARDASIL) vaccine side effect was reported on 03/04/2009. Female patient, child 11.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from the patient's sister concerning her sister with no pertinent medical history or drug reactions or allergies who on unspecified dates was vaccinated with three doses of GARDASIL. There was no concomitant medication. After the third dose of GARDASIL, the patient experienced numbness in both legs. The consumer reported that the patient could not walk so she was admitted to a hospital for one week. When the patient was in the hospital they did many tests (also reported as no lab tests were performed) but could not find anything wrong and the patient was told it was psychological. The consumer also reported that in 2009, ~recently~, the patient was just administered a fourth dose of GARDASIL, but no adverse event was involved. At the time of this report, the outcome was unknown. No further information is available. 4/23/09 MR received from PCP with vax rec. Multiple vax received 9/10/07. Admitted to hospital 11/11-14/2007 with D/C DX: Convulsion Disorder (no mention of convusions in MR-conversion d/o dx by psych). Anxiety, convulsion reaction and asthma. Pt presented with increasing weakness and numbness of arms and legs. Recent viral gastritis. Psych consult to deal with family related anxiety. Able to walk with crutches at d/c. HPV#2 given 11/15/07. No mention of hospitalization in record. MD unaware of admission. Viral syndrome 3/27/08. HPV#3 5/13/08. OV 6/24/08 to r/o UTI 2' to urinary incontinence x 10 with dysuria. Tx abx. Reporting leg pain and dizziness 10/24/08. Diarrhea reported 12/27/08. Stomach pain and diarrhea reported 2/3/09. Recieved 4th dose Gardasil 2/26/09 4/27/09 MR received for DOS 11/11-14/07 with DX as above. Conversion Disorder (not convulsion disorder mentioned by neuro consult). Admitted to r/o TM or GBS. Pt reports cannot feel legs, arms are weak, with neck pain 7/10. Pt reports recent virus. (+) Waddell's sign. Medical w/u has been (-), so physch consult requested.. Pt has had multiple stressors recently. (+) insomnia. DX: Conversion" None. PMH: obesity. scoliosis. folliculitis. mild SAR/RAR.Unknown. Labs and diagnostics: 11/11/07- MRI T-spine WNL. MRI brain (+) for CSF attenuation in L cerebellopontine angle-likely archnoid cyst. . During the same period patient was treated with None. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #341419
HPV (GARDASIL) vaccine side effect was reported on 02/12/2009. Female patient, child 12.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "8/1/08- 1st shot- fainting began, headaches. 10/2/08-2nd shot- fainting + headaches continue inability to sleep or concentrate, inability to see or have use of her legs during fainting, sensitive nerves. 5/18/09 hospital records received DOS 3/5/09 to 3/6/09. FINAL DIAGNOSIS: Migraine - non-classic type, urinary tract infection Post vaccination: light headedness, feels that she will fall over, floating in lower extremities, and tunnel vision. Later insomnia, syncope on standing, fell backwards with stiffening in legs. 4/5 strenght L upper extremity. Urinary tract infection. 5/18/09 medical records received - includes neuro consult - DOS 12/1/08 to 4/8/09. FINAL DIAGNOSIS: Seizures presented as syncope Post vaccination: with change of position sees dark spots. Fell backwards with episode of rigidity. Weight loss, lower abdominal pain. Acne forehead, cheeks, chin, chest. URI with cough, congestion, rhinorrhea, hoarse, sore throat, chest heavy, difficulty taking deep breaths. Neurology consult - headaches, stress, people picking on me," NoneAsthma"MRI; EEG; Heart monitor; Blood work. 5/18/09 hospital records received DOS 3/5/09 to 3/6/09. LABS and DIAGNOSTICS: Urinalysis - hazy, protein trace, leukocyte esterase, WBC 2, RBC 1, bacteria moderate, squamous epithelial cells 5, tr" . During the same period patient was treated with "None 5/18/09 medical records received DOS 12/1/08 to 4/8/09. benzaclin, albuterol, Pediazole". Patient recovered.

HPV (GARDASIL) Side Effects Report #342430
HPV (GARDASIL) vaccine side effect was reported on 03/13/2009. Female patient, 14.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a licensed visiting nurse concerning a 15 year old female patient with no pertinent medical history and no know drug allergies, who on 26-JUN-2008 was vaccinated with the first dose of GARDASIL (lot# 660391/0063X) 0.5ml intramuscularly. There was no concomitant medication. Subsequently the patient experienced insomnia that lasted for a period of three weeks. Patient was seen at the practice. No lab diagnostic studies performed. At the time of this report the patient had recovered. Additional information has been requested." NoneNone . During the same period patient was treated with None. Patient recovered.

HPV (GARDASIL) Side Effects Report #342647
HPV (GARDASIL) vaccine side effect was reported on 03/13/2009. Female patient, 20.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a physician concerning a 20 year old female patient with no pertinent medical history and no known allergies/drug reactions who on 25-Jan-2008 was vaccinated with the first dose of GARDASIL (lot#659962/17400) 0.5ml intramuscularly. The patient received the second dose of GARDASIL (lot# 660389 / 1968U) 0.5ml intramuscularly on 29-Apr-200. Concomitant therapy included ~~~~ 4/8/09 GYN records received. OV 1/28/08 with HPV#1 given-1740U. HPV#2 given-1968U. Report states no prior rxn to vaccine. 4/21/09 Office notes received from PCP for 2 OVs 3/4/09 with dx: Anxiety and 3/24/09 with DX: Herpes simplex oral-resolving. First seen for c/o 1-2 month hx of anxiety, tenseness, tremoulousness, palpitations, dyspnea, irritability, insomnia and difficulty relaxing r/t heavy school load. PE WNL. Returned 3/24/09 with R sided oral cold sore and swollen gland under the neck, now resolving. Pt reports no other c/o." NoneUnknown . During the same period patient was treated with Minocycline. Patient recovered.

HPV (GARDASIL) Side Effects Report #343798
HPV (GARDASIL) vaccine side effect was reported on 03/27/2009. Female patient, 13.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Fever 103 at 10:45 am 3/26/09, shaking. Poor sleep night of 3/25/09." NoneExercise- Induced BronchospasmCBC . During the same period patient was treated with VENTOLIN HFA. Patient recovered.

HPV (GARDASIL) Side Effects Report #343922
HPV (GARDASIL) vaccine side effect was reported on 04/10/2009. Female patient, 18.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "within 20 mins of injections, pain, stiffness, extreme fatigue, lethargic . Then experienced cont. pain and soreness, stiffness on and off for next week and 1/2 when became increasingly worse with joints locking up, severe pain and stiffness, fatigue, fever, swelling of joints. Small relief with pain meds. 4/29/009 Received PCP medical records of 8/25/08-4/8/2009. FINAL DX: polyarticular arthralgias Records reveal patient experienced good general health & was on OCP on 3/23/09 for HPV#1 & Menactra. RTC 4/8 & reported malaise since day after vax & then developed progressively worsening joint pain, stiffness & swelling w/difficulty sleeping & generalized body aching x 1 wk. Tx w/NSAIDS & heat. Patient still has pain in the joints and stiffness in the joints at times. We would not make the same decision, if we had it to do over again." none also received TB test/neg"PMH: Irregular menses. Juvenile osteoporosis. Heart murmur in childhood. Allergy: suprax. Family hx: CAD, asthma, DM, CVA, colon, cervical & breast cancer.""Tests done on 4-8-09, show high SED rate and low blood iron levels. LABS: H/H 9.7/29.0(L). ESR 30(H). CMP, TSH, T4, mono WNL. ANA (+). RF neg. Uric acid 3.7(N)." . Patient recovered.

HPV (GARDASIL) Side Effects Report #345222
HPV (GARDASIL) vaccine side effect was reported on 04/14/2009. Female patient, 21.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from an office nurse concerning a female who on an unknown date, was vaccinated with the third dose of GARDASIL (lot# not reported). Subsequently the patient was diagnosed with Guillain Barre by a neurologist. Upon internal review, Guillain Barre was considered to be an other important medical event. In follow-up, the nurse revealed that the approximately 22 year old patient received two doses of GARDASIL on 18-JUL-2007 (lot# 658100/0525U) and 20-DEC-2007 (lot# 659439/1267U). Additional information has been requested. 8/26/09 MR rec'd for DOS 5/6-12/2008 with D/C DX: Guillain-Barre Syndome, s/p 5 days of IVIG. ADHD. Pt initially presented to ER with 9 day hx of ascending numbness and weakness to the level of the abdomen. 2 prior ER visits, but presented again with chest pressure, decreased strength, difficulty walking, and worry re: condition. PE (+) for decreased strength and sensation. DTRs trace or absent. Admitted for IVIG. Pt had autonomic instability with tachycardia and HTN, insomnia, H/A and constipation, somewhat improved by d/c. Transferred for rehab 5/12/08 ICD9-357.0, 787.20, 349.0,314.01, 9/4/09 Hospital records received DOS 5/23/08 to 6/9/08. Assessment: Guillain-Barre' Syndrome Previous hospital stay complicated by respiratory distress / insufficiency. Transferred and placed on respiratory support (BiPAP). 7 days of plasmapheresis. Dysphagia, PEG tube. Difficulty activating facial muscles. Decreased muscle strength. Deep tendon reflexes absent lower extremities, trace in upper extremities. Anemia. Headache. Discharge to rehabilitation." Unknown PMH: ADHDUnknown Labs and Diagnostics: alk phos (H) at 137. AST 112. ALT 131. MRI brain WNL. ANA (+). CSF WNL. 9/4/09 Hospital records received DOS 5/23/08 to 6/9/08. LABS and DIAGNOSTICS: Elevated serum transaminase levels. CBC - WBC 3.7 X10 . During the same period patient was treated with Unknown. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #345239
HPV (GARDASIL) vaccine side effect was reported on 04/14/2009. Female patient, child 11.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a consumer concerning her daughter, a 11 year old female patient, with no known drug allergies, joint pain and problems with bones who was vaccinated with her first and second doses of GARDASIL (lot number, site and route not reported) several months ago. There was no concomitant medication. A few months ago, the patient experienced a fever, vomiting, headache, blurred vision, trouble sleeping, chest pain and dizziness. MRI and other unspecified lab work were performed on an unspecified date (no result reported). The events persisted at the time of this report. An unspecified medical attention was sought. Additional information has been requested." Arthralgia; Bone disorderUnknown . During the same period patient was treated with None. Patient recovered.

HPV (GARDASIL) Side Effects Report #344447
HPV (GARDASIL) vaccine side effect was reported on 04/20/2009. Female patient, 14.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "fever, vomiting,malise, headache could not get out of bed for 2 weeks after 1st shot. Developed periphreal neurapathy within 30 days of 1st shot. However it took 3 months to diagnose. Gastritis several times. Migraines constantly, fainting with muscle weakness...can not use legs for hours after faintinf, bloody stools, paralysis in right arm immediately after third vaccine. Pallor, clamminess, amennorhea no period since first vaccine. fatigue, insomnia, sleep apnea, chest pain, pins and needle sensations throughout extremities, sinusitis several times, pins and needles feelings in stomach, fevers on and off, slurred speech. She has been very ill since first vaccine and in a lot of pain. 5/1/09 Received vaccine & PCP medical records of 11/14/06-1/9/2009. FINAL DX: none provided Records reveal patient experienced shooting paine & numbness of extremities 2 wks prior to HPV #1 & flu shot. RTC w/recurrent depression, left plantar fasciitis, migraine HAs. Seen in ER 3/13/08 for HA & dx w/ethmoid sinusitis, tonsillitis & URI. RTC w/viral gastroenteritis, right CTS, recurrent allergic rhinitis. 8/18/08 w/spells x 3-4 yrs which had increased in frequency x 3 wks; dx w/presyncopal episodes. Seen in ER w/dx gastroenteritis. Referred to Neuro for syncope. Missed several days of school. RTC for LBP s/p fall, gastritis w/bloody stools. 6/15/09 Received consultant medical records of 1/29/08-5/26/2009. Pulmonology records reveal patient experienced sleep disturbance, obstructive sleep apnea, increasing obesity, nasal congestion, and allergic rhinitis. Residual cough. Low bloodpressure. ENT - intranasal mucosal edema and clear drainage, deviated septum, mouth and oral cavity small, enlarged tonsils, redundant pharyngeal mucosa, obese neck. Tonsillectomy / Adenoidectomy. Neurology - patient c/o burning in feet, dizzeness, fainting spells, clamminess, sweating, shooting pains in wrists /ankles, difficulty focusing / concentrating. Examination is unremarkable. Ophthalmologic evaluation reports some loss of peri" "hypoglycemia, PCOS, depression""mold, cockroaches, smoke, dust, dust mites, trees, grass,perfume allergies PCOS, blounts, hypoglycemia, PMH: exudative pharyngitis, metabolic syndrome w/hirsutism, Type II DM w/peripheral neuropathy, metromenorrhagia, morbid obesity, Blount's disease w/left tibial lengthenins & reshaping via cage, left gastrocnemius contracture, bronchitis, URI, sleep apnea, restless leg syndrom""EKG, Holter Monitor, EEG, Sleep Studies, Heavy Metal test, CBC, Urinalysis, Upper GI, Stool sample, Hepatitis test, CBC, metobolic study, Cat Scans, MRI, Has seen neurologist, pulmonary doctor, podiatrist, endocrinologist, tons on blood wor" . During the same period patient was treated with "lo-ogesterl, vitamins, metanx, glucophase, prozac, trazadone, spironlactone". Patient recovered.

HPV (GARDASIL) Side Effects Report #344938
HPV (GARDASIL) vaccine side effect was reported on 04/27/2009. Female patient, 22.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "autoimmune disease fibromyalgia, raynods, numbness, flushing/sweats, anxiety,headaches, exhaustion to the point where its impossible to work, total body pain constantly,hair loss, vision problems,stiff and sore muscles,insomnia, trouble focusing and concentrating, memory loss, weakness, trouble breathing,and dizziness near syncope. All the side effects happened and intensified during December through January so I had an anti nuclear antibody blood test that was positive revealing the autoimmune disease fibromyalgia and raynods. My ANA blood test has come back positive several times. The doctors put me through a ridiculous amount of tests to try to figure out a diagnosis and why this had come out of nowhere. They thought I had at one point every different type of autoimmune disease including lupus but settled on FIbromyalgia with raynods and the possible beginnings of Lupus. I have to frequent a rheumatologist, neurologist,and primary care doctor several times a month. The side effects have made me very weak and unable to live my life normally, its hard for me to work. I teach children which take a lot of energy when I have none what so ever. I used to be strong and able to work out and ride horses and live a healthy active lifestyle, now I cannot enjoy any of it. My body is in such pain all the time that its impossible for me to have a normal life. I wanted this vaccine to help prevent problems, when all it did was destroy my life. 5/18/09 Vax info received. HPV#1 7/7/08 0847X. HPV#2 9/8/08 0546X. HPV#3 1/7/09 0546X. 7/15/09 Rheumatology consult rec'd dated 1/29/09 to 6/8/09 with final dx: Inflammatory arthritis, arthralgias. Pt presented with c/o numbness and bluish discoloration of the feet. Pt also has a blackish scab on the R 3rd toe. Pt reports feeling achy all over. PE (+) for cold fingers and toes and bluish discoloration of toes. (+) fibromyalgia tender points. Assess: Raynaud's. ANA (+). Scoliosis. Possible fibromyalgia. F/U 3/5/09 with dx: fibromyalgia. Pt reporting poor sleep" PMH: scoliosis. tonsillectomypositive anti nuclear antibody blood test. Labs: ANA 1:640. RF (-). Anti-DNA (-). Echo WNL. CXR WNL. US R LE (-) for DVT. . During the same period patient was treated with "pentoxifllyne,". Patient recovered.

HPV (GARDASIL) Side Effects Report #346337
HPV (GARDASIL) vaccine side effect was reported on 05/14/2009. Female patient, 16.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "During the series of 3 injections and after the patient developed utis, uris, strep throat 3 times, joint pains, muscle weakness, numbness, insomnia, mental status changes, POTS, clinical lyme disease, rheumatoid arthritis, gastrointestinal disturbances following vaccination of gardasil. Two years later still has not recovered. Recently developed presepal cellulitis and was hospitalized. 7/21/09 Medical records received DOS 1/24/08 to 4/9/09. Assessment: Chronic pain in neck, back, and mid spine region. Patient presents with missing school, severe joint pain neck and back - hurt all the time. Reports eyes dilated. Constantly tired. Pain also shoulders, wrists, hands, ankles, feet. Difficulty walking. Hypersensitive. emotional. Acute tracheitis, sore throat. Myalgias, myositis. Fibromyalgia. Feels sad. Depression, difficulty sleeping. Parent says patient ~talking crazy things~ and wanted to kill herself. Crying hysterically. Therapeutic abortion. Cafe-au-lait spots noted. Limitation of cervical range of motion. 7/24/09 Cardial consultant records received DOS 4/22/09. Assessment: Chronic fatigue, chronic Lyme disease, autonomic disfunction, postural orthostatic tachycardia syndrome. Patient presents with dizziness, 'declining cognitive' and poor memory. Frequent headaches and insomnia. Generalized body aches. Nausea. Hand and feet are cold. Head felt foggy, lightheaded. 'Marijuana intake' 7/27/09 Hospital records received DOS 5/9/09 to 5/11/09. Discharge Diagnosis: Severe Periorbital Cellulitis, Chronic Lyme Disease, Seronegative Rheumatoid Arthritis, Post reactive Streptococcal Arthritis, and POTS, Chronic pain/chronic opiates, Polyarthralgia, Euthyroid Sick Syndrome. Patient was extracting blackheads and plucking ingrown eyebrow hairs, presents with red swollen right eyelid and face with prurulent areas, tenderness, scaling. Marked facial erythema and edema on the right, left side much less red and swollen. Honey-crusted papules. Difficulty opening right eye. Poor eye contact, flat affect. Drowsy" Mono diagnosed 5/2006 - shot given 12/2006 at pediatrician's urging"none. 7/21/09 Medical records received DOS 1/24/08 to 4/9/09. Tonsillectomy. Infectious mononucleosis, chronic fatigue syndrome. Spinal tap headaches, Strep throat, ADD, ruptured ovarian cyst. Rheumatoid arthritis. Has abused alcohol and used drugs. 7/27/09 Hospital records received DOS 5/9/09 to 5/11/09. Allergies to hydrocodone and provigil. Babesiosis.""Head Mri-normal, Cat scan body-normal except for mild degenerative disc disease of the thoracolumbar junction,lyme igenex 41k 58k igg positive-igm 30+,31-ind,39-ind,41-ind, babesia 1:20 igm titer, CD57-low,EBV igg high,parvo-igg high,crysta" . During the same period patient was treated with none. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #346885
HPV (GARDASIL) vaccine side effect was reported on 05/14/2009. Female patient, 14.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a pharmacist reported that he received a call from a mother concerning a 14 female daughter who was vaccinated with a first dose of GARDASIL (date, dose, route and lot number unknown), laboratory performed were magnetic resonance imaging and blood work (date and results unknown). The mother reported her daughter, experienced adrenal insufficiency, curvature of her spine, bouts of intense abdominal cramps, nausea, vomiting and headache. The patient's symptoms began one week after administration. The patient sought specified medical attention a neurologist and gastroenterologist. The outcome was not recovered. The vaccine was administered with a different facility. Follow up has been received from a patient's mother who reported that in addition to the previous symptoms, the patient was experiencing insomnia, fever, joint pain, chronic cough, severe migraines, back pain. The patient was 15 years old (also reported by a pharmacist as 14 years old) and received her first dose of the vaccine on 17-OCT-2008 and the second dose on 19-DEC-2008. The patient had been tested for Lyme disease, mononucleosis, West Nile virus and rheumatoid arthritis with negative results. The patient was seeing a chiropractor and alternative medicine doctor. Follow up information his been received from a registered nurse which reported that on 17-OCT-2008 the patient received a dose of FLUZONE (lot no. U274AA) and on 19-DEC-2008. It was reported that the patient did not received any concomitant vaccinations. The nurse reported that the patient had 5 follow up visits with the physician since 19-DEC-2008. The patient was seen in the office on 05-JAN-2009. At this visit the patient had complained of headaches. The registered nurse refused to five additional information concerning the patient. Additional information has been requested. 5/28/09 Received vaccine records & PCP medical records for 11/5/2008-3/18/2009. FINAL DX: menstrual migraine, migraine, flu, bronochitis, viral syndrome. Records reveal patie" "Unknown PMH: migraines, daily HA since 5/07, palpitations, lightheadness, possible IBS, insomnia, iron deficiency anemia, chickenpox, lactose intolerance, irregular menses. Allergy: red dye. Family hx: breast cancer, hyperlipidemia, CAD.""Magnetic resonance, C-spine and brain: Normal; Diagnostic laboratory, Diagnostic laboratory, Lyme disease teste-negative results; Diagnostic laboratory, rheumatoid arthritis-Negative results; Serum Epstein-Barr, Negative results; Serum West" . During the same period patient was treated with Unknown. Patient recovered.

HPV (GARDASIL) Side Effects Report #347953
HPV (GARDASIL) vaccine side effect was reported on 05/22/2009. Female patient, 18.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Patient complained of ~high~ fever several hours after injection (although did not have a thermometer). Sweating, could not sleep, numbness and tingling in both legs. Symptoms resolved in approximately 24 hours. Was patient's 2nd injection." Possible URInone . During the same period patient was treated with Low-ogestrel. Patient recovered.

HPV (GARDASIL) Side Effects Report #350863
HPV (GARDASIL) vaccine side effect was reported on 07/06/2009. Female patient was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a physician concerning a female patient with asthma who on an unknown date, was vaccinated with the first dose of GARDASIL. Concomitant therapy included MAXAIR. A couple of days later after receiving GARDASIL, the patient started presenting with anxiety, dementia, panic attacks, loss of sleep, weight loss, hallucinations and hyperventilation. The patient was put on antidepressants (unspecified) and her symptoms got worse and she was taken to the ER on 02-FEB-2009. After the antidepressants the patient experienced burning, sweating, tics, rapid heart beat and vocal grunt and was admitted to the psychiatric hospital. The patient will not receive further doses of GARDASIL. The patient was released since she was feeling a little better and started eating, however she is showing early signs of dementia. The patient's adverse experiences were considered to be disabling. Additional information has been requested." AsthmaUnknown . During the same period patient was treated with MAXAIR. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #350870
HPV (GARDASIL) vaccine side effect was reported on 07/02/2009. Female patient, 17.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Pt had 3rd GARDASIL Injection and was diagnosed with transverse myelitis and is being treated with steroids. Pt has LE weakness. 7/17/09 Medical records received DOS 6/25/09. Assessment: Skin sensation disturb, toxic effect venom, cervicalgia. Patient presents with entire left side numb, neck pain and trunk area tingling X 3 days. Not able to sleep because of neck pain, paresthesias. Decreased ROM of cervical spine. 7/23/09 Hospital records received DOS 6/30/09. Diagnosis: tranverse myelitis, hypertension, anxiety, constipation, urinary retention. Patient presented with worsening neck pain and weakness below the waist. Numbness left side of neck, shoulder, arm. Babinski (+) No patellar reflex on right. Tremor in hands. Weakness, paresthesias, brisk tendon reflexes, clonus ankles, alterations in temperature and vibration sense. Neck stiffness." None"Bee stings. 7/23/09 Hospital records received DOS 6/30/09. Gravida 1, para 0. Chickenpox. Wheezing as a toddler. Smokes. Alcohol. Marijuana. Allergy to a venom."7/17/09 Medical records received DOS 6/25/09. LABS and DIAGNOSTICS: Monofilament feels different on left. CBC - Lymphocytes 18% (L). TSH - WNL. Vitamin B12 - WNL. 7/23/09 Hospital records received DOS 6/30/09. LABS and DIAGNOSTICS: Urin . During the same period patient was treated with DEPO-PROVERA. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #351015
HPV (GARDASIL) vaccine side effect was reported on 07/08/2009. Female patient, child 12.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a consumer concerning her 12 year old student daughter with no known drug allergies who on 09-MAY-2007 was vaccinated with the first dose of GARDASIL. On 08-AUG-2007 the patient was vaccinated with the second dose of GARDASIL. In September 2007, the patient developed severe nausea and severe dizziness, unable to function-can't walk, stand up, read, no computer work. The patient could not go to sleep at night because when she closed her eyes the dizziness was even worse, black outs. Symptoms lasted from 10 minutes to several hours. The patient missed a total of 30 days of school in 2007. This year she missed 27 days of school. Symptoms continued. Studies of X-rays, MRI, CT scan, vestibular testing, sleep studies, EEG were all negative. Severe nausea, severe dizziness, black outs, can't walk and missed a total of 30 days of school in 2007 and 27 days this year were considered to be disabling and other important medical events by the reporter. Additional information has been requested. 9/28/09 Note in vaccine records. Patient had 2 doses of Gardasil. Did not complete series." None"X-ray, negative; magnetic resonance, negative; computed axial, negative; sleep study, negative; electroencephalography, negative" . During the same period patient was treated with Unknown. Patient recovered.

HPV (GARDASIL) Side Effects Report #351793
HPV (GARDASIL) vaccine side effect was reported on 07/18/2009. Female patient, 26.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "at 9:00 am I had the 3rd gardasil shot and about 10 minutes later I was feeling sick, nausea,diarriah, stomache pains, insomnia, heart palpatations,feeling like my skin is on fire.sweaty, cold and hot flashes." anxietyn/a . Patient recovered.

HPV (GARDASIL) Side Effects Report #352152
HPV (GARDASIL) vaccine side effect was reported on 07/22/2009. Female patient, 21.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Seizures, Slurred speech, Dizziness, muffled hearing, blurred vision, involuntary joint movement, easily frustrated, muscle spasms, taste and memory disturbances, loss of sleep, extreme stress and anxiety related to symptoms and treatments. 7/23/09 Consultant records received DOS 7/31/07 to 7/13/09. Assessment: Partial seizure emanating from the left hemisphere. Patient ~felt like something would happen~ Then unable to speak appropriately, jumbled words, could not speak properly. Right arm made involuntary movements, felt like she was out of her body. Make loud noises. Hearing felt muffled. Felt on edge and not as sharp for 24 hours. Slightly mumbles, tired at times. Recurrent episode. Blotches in vision, headache. Agitated, irritability - Keppra. ICD-9 Code: 345.11, 780.39, 784.0 7/28/09 Medical records received DOS 5/30/07 to 1/29/09. Patient requests Gardasil vaccine. 1st dose of Gardasil given. Oral contraceptive changed from Desogen to Seasonique. Has had two seizures, on Keppra. 2nd, 3rd doses of Gardasil given. Denies any side effects from this medication (Gardasil)." N/AN/A 7/28/09 Medical records received DOS 5/30/07 to 1/29/09 Caffeine."MRI, Multiple EEG, Multiplte Doctor Visits, all from having to traveling long distances. 7/23/09 Consultant records received DOS 7/31/07 to 7/13/09. LABS and DIAGNOSTICS: MRI - Normal. MRI angiogram normal. WBC / CBC normal. Comprehensive" . During the same period patient was treated with N/A 7/28/09 Medical records received DOS 5/30/07 to 1/29/09. Oral contraceptives. Oral contraceptive changed from Desogen to Seasonique.. Patient recovered.

HPV (GARDASIL) Side Effects Report #352421
HPV (GARDASIL) vaccine side effect was reported on 07/27/2009. Female patient, 17.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Nausea & vomiting, abdominal pain, joint pain, numbness & tingling in hands & feet, fatigue, weight loss. Unable to eat certain foods. Developed allergy to wheat. These symptoms started 1 to 2 weeks after 1st vaccine. Pt stated felt like ~she was 80 yrs old.~ Started wheat free diet, visited doctor, lab tests for celiac disease negative, numerous lab tests (lyme titer, cbc, rheumatoid workup, ANA, Sed rate, lupus and all negative. 2 months after vaccine peripheral neuropathy, joint pain symptoms improved. Continues with abdominal pain, weakness, weight loss & difficulty with foods. Diarrhea begins and continues to present. Work up by GI specialist includes EGD, colonoscopy, CT's, MRI, GI series, video capsule endoscopy, numerous lab studies. Allergy testing showing allergy to wheat. Positive for fructose malabsorption. Wheat free & fructose free diet. Work up continues after 1 year to find source of abdominal pain and watery diarrhea. 7/30/09 PCP records received 7/11/08 to note written 7/28/09. Initially presented 7/11/08 request to be tested for celiac disease. Reports 2 yr hx of abdominal pain, recently improved on wheat-free diet. Returned 8/11/08 with c/o 2 months hx of ~everything hurting~- joints and muscles, fatigue, decreased sleep, sensitive hearing. Labs all WNL except (+) EBV Ab IgG showing recent infection. 10/8/09 Hospital records, DC summary received, service dates 3/16/09 to 3/18/09. Assessment: Chronic complex of abdominal pain with diarrhea. Patient developed myalgias, asthenia, fatigue, arthralgias, nausea and vomiting - now resolved. Lost weight. Constipated. Patient now presents with abdominal pain and postprandial diarrhea. Abdomen - diffuse tenderness to palpation. ICD-9 Codes: 564.1 Irritable bowel syndrome, 787.91 Diarrhea." Pectus Excavatum PMH: abdominal pain. 10/8/09 Hospital records 3/16/09 to 3/18/09. Blastocystis hominis infection. Possible Joubert's Syndrome.Small bowel biopsy with intraepithelial lymphocytes. Labs: EBV IgG (+). 10/8/09 Hospital records 3/16/09 to 3/18/09. LABS and DIAGNOSTICS: CT Scan Abdomen/Pelvis - Abnormal. . Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #353080
HPV (GARDASIL) vaccine side effect was reported on 08/03/2009. Female patient, 23.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a physician concerning a female who in January 2009, was vaccinated IM with the second 0.5ml dose of GARDASIL (lot# not reported). The patient exhibited ~multiple sclerosis (MS)-like symptoms~. The date of onset of the symptoms was unknown. The patient was hospitalized overnight at hospital for testing to rule-out multiple sclerosis. The physician relayed that unspecified test results were ~non-specific~. The dates of hospitalization were unknown. The physician did not provide details of the specific symptoms experienced by the patient but added that ~the symptoms are improving.~ Follow up information was received via telephone call from the patient's mother who worked in the doctor's office and was not a Health Professional provided the patient's full name and birth date. It was reported that the patient was 23 year old and had received 2 doses of GARDASIL. The patient received the first dose of GARDASIL from her gynecologist (GYN) physician (date, dose and lot number unknown to reporter). The patient received the second dose of GARDASIL on 12-NOV-2008 (lot# 659184/0843X) (previously reported as January 2009). The patient began having the following symptoms in the middle of December 2008; ~Swelling in her arm, twitches, constant back pain, could not walk at times~. The patient was hospitalized of over night, early in 2009 to rule out (R/O) multiple sclerosis (MS) (hospital name and hospitalization dates not reported). The patient's mother stated that the patient could walk and was improving. Follow up information was received via telephone call from a person from the patient's gynecologist's office who provided the doctor's address and reported that the patient received the first dose of GARDASIL on 05-MAY-2008 (expiration date 14-JUN-2009). Additional information has been requested. 8/7/09 Medical records received DOS 11/12/08 to 7/28/09. C/O heartburn, rosacea, joint stiffness. Second dose of Gardasil administered. Post vaccination patient presents with back pain, insomn" "8/7/09 Medical records received DOS 11/12/08 to 7/28/09. C/O heartburn, rosacea, joint stiffness.""Unknown. 8/10/09 Hospital records received DOS 12/26/09 to 1/24/09. B12 deficiency, bipolar disease, asthma. Septoplasty. Alcohol, tobacco use. Fibromyalgia. Sulfa allergy."Unknown. 8/7/09 Medical records received DOS 11/12/08 to 7/28/09. LABS and DIAGNOSTICS: Mantoux. 8/10/09 Hospital records received DOS 12/26/09 to 1/24/09. LABS and DIAGNOSTICS: MRI Cervical Spine - Right sided predominant disc bulge at . During the same period patient was treated with Unknown. 8/7/09 Medical records received DOS 11/12/08 to 7/28/09. 'B12 pills'. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #353201
HPV (GARDASIL) vaccine side effect was reported on 08/05/2009. Female patient, 15.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "48 hours after the vacination of Gardasil, I has a reaction. My legs swelled and I had small red bumps all over my legs. I couldn't walk because of the pain and large amout of swelling in my knees and ankles. About 8 days after I had severe abdominal pain with vomiting and fever. I went to the doctor about a week after the shot because my legs were swelling all over and so were my elbows. The dots were spreading and they stung. She looked and examined me and we concluded I had HSP. It's an autoimmune desease that causes the blood veins to pop and leak. It is supposed to go away after 4-8 weeks. I have had it since Sep. 11th of 2008. We went to a skin doctor to make sure and he took a biopsy of my leg in 2 places and it was in fact HSP. About a month or 2 after we found out what I had, we started noticing I got sick very easily. I had my blood and urine tested and the doctors saw that I had an extremely high level of protein and blood in my urine. In the blood they took they saw that my iron was low and I had a low white blood cell count. We kept testing one or twice every 2 or 3 weeks. The protien and blood went up and down but was never at a normal or healthy amount. We then went to a doctor. He looked at my urine and blood and decided to preform a kidney biopsy. He saw that I had scarring on my kidneys and found that I have an IgA protien that causes my kidneys to overwork. I was put on blood pressure medicine and bottomed out so we stopped that. We are still to this day trying to find out what to do about the situation. We've also been to an allergist. She saw that the ingredients in Gardasil along with the protien in my body are reacting. I can't take any medication because I might have a reaction. Plus it goes to my kidneys which could cause damage. I might be put on steroids but we aren't sure. I just hope more people know about Gardasil before someone else gets what I have or worse. 8/17/09 PCP medical records received DOS 8/12/08 to 7/13/09. Assessment: Henoch-Schoenlein Purpura. Patient presents wit" "none. 8/17/09 PCP medical records received DOS 8/12/08 to 7/13/09. Oral candidiasis, Diflucan. Hyperhydrosis.""none. 8/17/09 PCP medical records received DOS 8/12/08 to 7/13/09. Hyperhydrosis, allergic rhinitis, recurrent otitis media, chronic constipation, GERD. 8/17/09 Consultant records and labs received DOS 11/18/08 to 8/10/09. Ear infections. Dental extraction."in the skin biopsy we found that i had hsp. kidney biopsy showed protein and scarring. it was all un normal. 8/17/09 PCP medical records received DOS 8/12/08 to 7/13/09. LABS and DIAGNOSTICS: ANA (+). Urine culture (+) - E. coli. Urinalys . During the same period patient was treated with none. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #354967
HPV (GARDASIL) vaccine side effect was reported on 08/21/2009. Female patient, 18.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Light-headed, dizzy, and nauseous immediately after vaccination. Since vaccination: headache, severe fatigue, numbness/tingling in extremities, sharp lower back pain, shoulder pain, hair-loss, memory 'fog'/concentration difficulties, breathing problems, muscle twitching, leg/arm cramping, insomnia, rapid heart beat, overall soreness, GI problems. 9/28/09 Neurology consult received DOS 2/13/08 to 6/6/2008 Assessment: Fibromyalgia. Restless leg syndrome. Patient presents with chronic lower back pain and paresthesias. Developed numbness and tingling ~pins and needles~ affecting anterior thighs/lower extremities and upper extremities, also including left hand. Gait affected, using wheelchair. Decreased sensation to light touch, pinprick and vibration right upper and lower extremities. Reflexes asymmetrical. Hoffman sign on right. Involutary loss of urine with activity. Post LP headaches, nausea, not eating or drinking very much. Muscle twitching. Difficulty falling asleep. 9/28/09 Rheumatology consult received DOS 2/15/08 to 2/29/08. Assessment: Likely demyelinating process of unclear etiology. Post lumbar puncture headache. Emotional lability brought on by stress of current illness. Patient c/o ~legs falling asleep~, lower back pain, ~pins and needles~ right and left arms. Thinning hair. Atypical Raynaud's symptoms, fingers appear dusky, livedo orver dorsum of hand. Eyes dry. Disconjugate movements extraocular muscles." nonenone. Chronic lower back pain. Seasonal allergies. Bilateral shoulder dystocia as a child. Wisdom tooth extraction. Migraine and tension headaches."Positive ANA, Postitive EEG. LABS and DIAGNOSTICS: Lumbar Puncture - Normal. MRI Head and Spine - Normal. Somatosensory Evoked Potentials - Abnormal. Visual Evoked Potentials - Abnormal. ANA (+). Sleep Study - Abnormal. MRI Back - heman" . Patient recovered.

HPV (GARDASIL) Side Effects Report #355483
HPV (GARDASIL) vaccine side effect was reported on 08/26/2009. Female patient, 14.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Severe headaches/migraines which cause sleeplessness, stomache aches, painful menstrual periods, nausea, always tired and feels like sleeping all the time, dizziness, heartburn. Unable to eat certain foods like fast food burgers. Had appendix taken out October 31, 2008 after one week of fevers above 103 for one week and emergency room visits. Finally after one week surgeon looked at records and determined appendix should have been removed one week earlier. 9/29/09 PCP records received DOS 1/5/07 to 8/7/09. Assessment: Transferred migraine, rebound analgesic headache, anxiety. Patient c/o recent headaches. Repeated strep pharyngitis. Plan B emergency contraception. Oral contraception initiated. Flat affect. Anxiety. Pelvic inflammatory disease. Headaches with photophobia and phonophobia. Pharyngitis/laryngitis with productive cough and wheezing. Bronchitis. Dry eczematous rash skin arms and legs. Abdominal pain, diarrhea, constipation. Gastroenteritis. Depo-Provera initiated. Muscle tension headaches. Insomnia. Painful intercourse. 9/29/09 Hospital records received DOS ER 10/25/08 Inpatient 10/31/08. Assessment: Appendicitis. Patient presented with right lower quandrant abdominal pain. Hematuria. Nauseous, vomited. Discharged from ER. Presents several days later with same complaints. Laparoscopic appendectomy. Pelvic inflammation. ICD-9 Codes: 540.9 Acute Appendicitis NOS, 784.0 Headache, 305.1 Tobacco use disorder/depend." none. 9/29/09 PCP records received DOS 1/5/07 to 8/7/09. Depression. Allergic rhinitis. Acne."allergic to cats. 9/29/09 PCP records received DOS 1/5/07 to 8/7/09. Strep Pharyngitis with fever, nausea and vomiting."9/29/09 PCP records received DOS 1/5/07 to 8/7/09. LABS and DIAGNOSTICS: Rapid Strep Test (+). CBC - WBC 13.0 Thous 10*3/ul(H) MPV 7.3 cu mic (L) Grans 81.1% (H) Lymphs 11.2% (L) ABS Gran 10.6 Thous (H). 9/29/09 Hospital records received . During the same period patient was treated with Doxycycline. Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #356192
HPV (GARDASIL) vaccine side effect was reported on 08/31/2009. Female patient, 19.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Information has been received from a physician concerning a 19 year old female patient who at the time of vaccination was with fever and congestion, on 02-Dec-2008 was vaccinated with 0.5ml of the ~first and only dose~ of GARDASIL (lot not reported) intramuscularly. There was no concomitant medication. On the same day of vaccination, 02-Dec-2008, the patient fainted, fell over, and had seizures after receiving her GARDASIL. The patient recovered at the office. She also experienced muscle soreness at the injection site, sleeplessness, and headaches after the vaccination from which she also recovered. Upon internal review seizures were considered to be other important medical event. Additional information has been requested." Fever; Respiratory tract congestionUnknownNone . During the same period patient was treated with None. Patient recovered.

HPV (GARDASIL) Side Effects Report #356323
HPV (GARDASIL) vaccine side effect was reported on 08/25/2009. Female patient, 13.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Aggression, seizures, rapid heart rate, brain damage, weakness, no sleep, changing skin color & textures, pain, numbness. 9/14/09 Hospital records received DOS 3/13/08 to 4/7/08. Assessment: Seizure activity with behavioral disorder. Insulin dependent diabetes mellitus. Patient transferred from another facility. Behavioral changes including defiance and disinhibited behaviors. Palpitations and transient sinus tachycardia. Agitation, aggression. Panic attacks. IVIG administration. 9/14/09 Hospital records received DOS 3/13/08 to 7/15/08. Additional information abstracted. Assessment: Meningoencephalitis with neurocognitive disturbance and disinhibition. Vaginal yeast infection. Patient c/o of palpitations. Emesis. Impulsive, compulsive eating behaviors. Increased lacrimation and salivation. Oral contraception. ICD-9 Codes: 345.90, 323.9, 341.9, 343.0, 293.0 307.51, 345.40, 343.9, 302.70, 312.9, 294.9, 310.1 293.84, 309.81, 296.90, 780.52, 250.92, 706.1, 274.9, 626.0 112.1 V15.81, V58.67, 313.81, 345.40, 293.89, 250.01, 298.9" NoneType I DM; Mild cerebral palsy but was an honor student. 9/14/09 Hospital records received DOS 3/13/08 to 7/15/08. Mild spastic diplegia cerebral palsy. Insulin-dependent diabetes mellitus.9/14/09 Hospital records received DOS 3/13/08 to 7/15/08. LABS and DIAGNOSTICS: Thyroid Ultrasound - Normal. TSH -Normal. Thyroid Peroxides Antibodies 66.1 elevated. EEG - Abnormal. MRI Brain - Abnormal. CBC - MCV 94 (H) RDWC 14.6% (H) N . Patient was hospitalized Patient recovered.

HPV (GARDASIL) Side Effects Report #356573
HPV (GARDASIL) vaccine side effect was reported on 09/04/2009. Female patient, child 12.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "Gardasil #1, Hep A #1, Menactra and flu given 10/5/07. Patient seen 5/12/08 and reported vomiting several times a week since thanksgiving (about 6-7 weeks after vaccine), limb pain, parasthesia's, headaches and fatigue. Patient still nearly 2 years later with vomiting several times a week, leg pain and tremors in her right hand/arm bad enough to interfere with school work and writing. She has had extensive GI and neuro evaluation with no diagnosis and no satisfactory treatment of symptoms. We do not know if this is related to gardasil but have begun to question it. She had a second gardasil 7/21/08. Of note, this patient has a sister with a severe mitochondrial disorder affecting her gut function, seizures, deteriorating mental function. 9/14/09 MR received from pcp which include multi-specialty consults dated from 10/2007 to 9/2009. In for WCC 10/5/07 with dx: Well. 4 vax given. Multiple visits after for pharyngitis, URI, tinea corporis, vomiting x 6 months with 8 lb weight loss, H/A, blurry vision, lower limb pain, decreased sleep, strep throat. Dx: Migraine/vomiting weight loss. Referred for labs and consults. By 9/3/09 reporting continued vomiting, tremors, muscle pain. GI consult with no specific dx made. 6/16/09 reports worsening of sx. PE (+) for fine tremor of tongue and hands. Neuro consult 6/29/09 with impression: Migraine complex. Returned for w/u for possible seizures due to episodes or tremors and jerking of the R side." wellmenorrhagia. PMH: Menorrhagia. ankle pain."carnitine level low, scope nl, fasting blood sugar, b12, folate, heavy metal screen, sleep study, ekg all nl as far as I know. EEG abnl--getting further studies. Labs and diagnostics: MRI head (-). Upper GI with small bowel WNL. EGD WNL" . During the same period patient was treated with "micronor at time of vaccination. Now on lo ovral, ponstel, zofran, carafate, lactaid, prilosec, amitryptyline". Patient recovered.

HPV (GARDASIL) Side Effects Report #357797
HPV (GARDASIL) vaccine side effect was reported on 09/21/2009. Female patient, 18.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "extreme fatigue, mono, chronic strep throat, Hashimoto's, extreme face and body swelling, aching muscles. Got first vaccine 7/10/09 Lot 0072X in conjunction with Menactra vaccine. Second vaccine 12/22/08 Lot 1311X. Went to college on cross country scholarship. Started off season great. She said she started noticing that she was having trouble running mid October and that her legs felt heavy. Starting getting facial swelling second week of January. Went to doctor and they said it was allergic reaction. Got sick in February - dx with strep. Didn't get better. Went to ER end of March with extreme facial swelling. Told her it was allergy and gave her prednisone. Re-dx with strep again in early April and then mono April 9th. Got really sick and could not get better. Extreme facial and body swelling. Dx with Hashimoto's June 29th. and started thyroid treatment. Was not able to return to college in August and is still home. Started getting muscle soreness in July. Made Gardasil connection 2 weeks ago and is going to begin treatment by doctor who has helped several other gardasil patients. 10/13/09 Medical records received, Dates of Service 4/19/09-8/10/09. Dx: Other Specified Acquired Hypothyroidism, Abnormal Weight Gain, Oligomenorrhea, Fatigue, Thyromegaly. Presenting Sx: Pt. experienced an approximately 40 lb. weight gain over a 1 to 2 month period, additionally she c/o fatigue, trouble sleeping and staying asleep, facial swelling, swelling around eyes, acne, one terminal hair periumbilical, headaches and a heavy period. Pt. saw a nutritionist and was put on a diet plan. She experienced menarche at age 13 and had irregular periods for several years (approximately 6 periods/yr.). Ortho Tri-Cyclene-Low was initiated which she took for several years, but stopped early this year after missing several pills. She re-started the pill a few months ago. Concomitantly, she takes Synthroid, Cosyntropin and furosemide. She was diagnosed with mononucleosis in April, and tested positive for Epstein-Barr Virus in May. H" none"Ortho-tryclen Low. 10/13/09 Medical records received, Dates of Service 4/19/09-8/10/09. PMH: Streptococcal infection 4/9/09, ear infections, mononucleosis 4/12/09, Allergic to Penicillin.""mono - April 9, 2009 and June 30, 2009. Two Positive strep tests. Tested positive Hashimoto's - 6/30/2009. Thyroid Uptake and ultrasound confirmed thyroid on low side of normal -nothing accounted for extreme symptoms she was experiencing." . During the same period patient was treated with none. Patient recovered.

HPV (GARDASIL) Side Effects Report #372938
HPV (GARDASIL) vaccine side effect was reported on 12/11/2009. Female patient, 15.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "After the first shot, Her eyes stopped focusing and she got migraines. After the second shot, which she recieved on 8/3/09 Her ankles started to swell and be very painful. Her legs turn blue. Her knees, ankles, hips, elbows, and shoulders fall out of place. Her hands, feet, and legs also swell. She is constantly cold. her hands and her head shake uncontrollably. She has heart palpatations. She cant sleep.At times it is to painful to get out of bed. She has trouble concentrating. She has been to the er, then doctor, then the er again, then the rheumatologist, the er again, and the childrens institute where she may have to stay for two or more weeks for intense physical therapy, although to week at this time. She has to be built up before she can begin." noShe had a goider on her thyroid."They tested for lymes disease, cancer, lupus, etc. All tests come back negative so they told us she hs reflex neurovascular dystrophy but weare not sure that the diagnosis fits." . Patient recovered.

HPV (GARDASIL) Side Effects Report #375016
HPV (GARDASIL) vaccine side effect was reported on 12/27/2009. Female patient, 23.0 years of age, was vaccinated with HPV (GARDASIL). Patient symptoms: Insomnia, "I received the Guardasil shot series over the course of 6 months. After the first shot given in May, I was nauseous and vomited. I also developed severe facial acne that I'm still experiencing, two weeks after the first shot. I don't remember any problems after the second shot in August. Severe symptoms started on the evening the third shot was administered December 14, 2009. I had constant tingling in my right limbs (arm, all the way down to the tips of my fingers, and leg, from the knee down to the foot): the shot was given in my right arm. I was still able to walk and use my arm. It was not a sharp pain, just constant. By Thursday, Dec. 17 at 4 A.M., the tingling was prevalent in all my limbs and my feet felt numb. I went to the emergency room on Thursday, Dec. 17, 3 days after the shot as the tingling was worse and not subsiding. They ran a CT scan to rule out shunt problems since I have a VP shunt. All was fine with the shunt. On Friday Dec. 18, I went to another emergency room so I could be evaluated by a neurologist. He ran reflex tests and everything was working well. He diagnosed neuropathy and said he thought it would eventually subside. That night I experienced swimming vision for a few minutes and a headache. I had trouble sleeping each night, unable to get comfortable in bed; the tingling seemed to be worse when lying down. The next day I felt dizzy, had an intermittent headache, and experienced vision problems if there were bright lights. By Sunday, the symptoms became less severe and over the course of the next week, diminished completely." None"Codine, Hydrocephalus, VP Shunt""I had also received the H1N1 vaccination as well as the flu shot, about a month a before taking this final Guardasil shot." . Patient recovered.


Loading

Please Share Your Insomnia from HPV (GARDASIL) 2009 Experience, Join the Discussion:
Medical Device Index: A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z
Source: VAERS
PatientsVille.com does not provide medical advice, diagnosis or treatment. The information contained on PatientsVille.com site has not been scientifically or otherwise verified as to a cause and effect relationship and cannot be used to estimate the incidence of adverse drug reactions or for establishing or changing of patient treatments.The material on this site is for informational purposes only, and is not a substitute for medical advice, diagnosis or treatment provided by a qualified health care provider.We hope you found our information about b>Insomnia from HPV (GARDASIL) 2009.