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Zoloft Irritability Side Effects

Zoloft Irritability Side Effect Reports


The following Zoloft Irritability side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Irritability, can occur, and what you can do about them.

A side effect could appear soon after you start Zoloft or it might take time to develop.



Somnolence, Abnormal Behaviour, Irritability

This Irritability side effect was reported by a consumer or non-health professional from US. A 77-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression. The patient was prescribed Zoloft (dosage: 100 Mg, 1x/day), which was started on NS. Concurrently used drugs:
  • Centrum (Unk)
When starting to take Zoloft the consumer reported the following symptoms:
  • Somnolence
  • Abnormal Behaviour
  • Irritability
These side effects may potentially be related to Zoloft.
Weight Decreased, Anxiety, Irritability, Dizziness, Fatigue, Menstrual Disorder

This Irritability Zoloft side effect was reported by a physician from US on Feb 12, 2014. A Female , 40 years of age, weighting 151.0 lb, was diagnosed with and was treated with Zoloft. The patient presented the following health conditions:
  • Weight Decreased
  • Anxiety
  • Irritability
  • Dizziness
  • Fatigue
  • Menstrual Disorder
. Zoloft dosage: 50 Mg, Daily. Additional drugs used at the same time: NA.
Anger, Irritability

This is a Zoloft side effect report of a 33-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: panic attack, who was treated with Zoloft (dosage:Unk, start time: NS), combined with: NA., and developed a serious reaction and a Irritability side effect. The patient presented with:
  • Anger
  • Irritability
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Zoloft treatment in female patients suffering from panic attack, resulting in Irritability.

Decreased Interest, Asthenia, Fatigue, Apathy, Irritability, Myalgia, Restlessness, Dyspnoea

A 30-year-old female patient (weight: NA) from US with the following symptoms: NA started Zoloft treatment (dosage: Unk) on NS. Soon after starting Zoloft treatment, the consumer experienced several side effects, including:
  • Decreased Interest
  • Asthenia
  • Fatigue
  • Apathy
  • Irritability
  • Myalgia
  • Restlessness
  • Dyspnoea
. Concurrently used drugs: NA. This finding indicates that some patients can be more vulnerable to developing Zoloft side effects, such as Irritability.
Anxiety, Fatigue, Apathy, Insomnia, Irritability, Nervousness, Myalgia, Negative Thoughts, Asthenia

A female patient from US was prescribed and started Zoloft on Nov 08, 2013. Patient felt the following Zoloft side effects: anxiety, fatigue, apathy, insomnia, irritability, nervousness, myalgia, negative thoughts, asthenia Additional patient health information: Female , 30 years of age, The consumer reported the following symptoms: . Zoloft dosage: Unk. Concurrently used drugs: NA.
Crying, Decreased Interest, Asthenia, Fatigue, Headache, Apathy, Psychiatric Symptom, Irritability

This report suggests a potential Zoloft Irritability side effect(s) that can have serious consequences. A 30-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): depression and used Zoloft (dosage: Unk) starting NS. Soon after starting Zoloft the patient began experiencing various side effects, including:
  • Crying
  • Decreased Interest
  • Asthenia
  • Fatigue
  • Headache
  • Apathy
  • Psychiatric Symptom
  • Irritability
Drugs used concurrently:NA. Although Zoloft demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Irritability, may still occur.
Anxiety, Decreased Interest, Asthenia, Fatigue, Apathy, Psychiatric Symptom, Feeling Guilty, Disturbance In Attention, Irritability

An adverse event was reported by a consumer or non-health professional on Oct 31, 2013 by a Female taking Zoloft (dosage: Unk) . Location: US , 30 years of age, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Zoloft side effects: anxiety, decreased interest, asthenia, fatigue, apathy, psychiatric symptom, feeling guilty, disturbance in attention, irritability. Additional medications/treatments:
Anxiety, Depressed Mood, Asthenia, Fatigue, Headache, Insomnia, Irritability, Abdominal Discomfort, Nervousness

This Irritability problem was reported by a consumer or non-health professional from US. A 30-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Zoloft (dosage: Unk). The following drugs/medications were being taken at the same time: NA. When commencing Zoloft, the patient experienced the following unwanted symptoms /side effects:
  • Anxiety
  • Depressed Mood
  • Asthenia
  • Fatigue
  • Headache
  • Insomnia
  • Irritability
  • Abdominal Discomfort
  • Nervousness
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Irritability, may become evident only after a product is in use by the general population.
Asthenia, Fatigue, Irritability

This is a Zoloft side effect report of a 30-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Zoloft (dosage: Unk) starting NS. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Asthenia
  • Fatigue
  • Irritability
This opens a possibility that Zoloft could cause Irritability and that some female patients may be more susceptible.
Fatigue, Asthenia, Apathy, Psychiatric Symptom, Insomnia, Irritability

This Irritability side effect was reported by a consumer or non-health professional from US on Oct 30, 2013. A patient from US , 30 years of age, was treated with Zoloft. Directly after treatment started, patient experienced the unwanted or unexpected Zoloft side effects: fatigue, asthenia, apathy, psychiatric symptom, insomnia, irritability. Zoloft dosage: Unk. These side effects may potentially be related to Zoloft.
Asthenia, Fatigue, Headache, Apathy, Psychiatric Symptom, Irritability

This Irritability side effect was reported by a consumer or non-health professional from US. A 30-year-old female patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Zoloft (dosage: Unk), which was started on NS. Concurrently used drugs: NA. When starting to take Zoloft the consumer reported the following symptoms:
  • Asthenia
  • Fatigue
  • Headache
  • Apathy
  • Psychiatric Symptom
  • Irritability
These side effects may potentially be related to Zoloft.
Apathy, Irritability, Myalgia

This Irritability Zoloft side effect was reported by a consumer or non-health professional from US on Oct 30, 2013. A Female , 30 years of age, was treated with Zoloft. The patient presented the following health conditions:
  • Apathy
  • Irritability
  • Myalgia
. Zoloft dosage: Unk. Additional drugs used at the same time: NA.
Anxiety, Depressed Mood, Asthenia, Fatigue, Apathy, Psychiatric Symptom, Irritability, Nervousness, Appetite Disorder

This is a Zoloft side effect report of a 30-year-old female patient (weight:NA) from US, suffering from the following symptoms/conditions: NA, who was treated with Zoloft (dosage:Unk, start time: NS), combined with: NA., and developed a serious reaction and a Irritability side effect. The patient presented with:
  • Anxiety
  • Depressed Mood
  • Asthenia
  • Fatigue
  • Apathy
  • Psychiatric Symptom
  • Irritability
  • Nervousness
  • Appetite Disorder
which developed after the beginning of treatment. This side effect report can indicate a possible existence of increased vulnerability to Zoloft treatment in female patients suffering from NA, resulting in Irritability.
Crying, Apathy, Feelings Of Worthlessness, Feeling Guilty, Disturbance In Attention, Irritability, Abdominal Discomfort, Nervousness, Myalgia

A 30-year-old patient (weight: NA) from US with the following symptoms: NA started Zoloft treatment (dosage: Unk) on NS. Soon after starting Zoloft treatment, the consumer experienced several side effects, including:
  • Crying
  • Apathy
  • Feelings Of Worthlessness
  • Feeling Guilty
  • Disturbance In Attention
  • Irritability
  • Abdominal Discomfort
  • Nervousness
  • Myalgia
. Concurrently used drugs:
  • Effexor Xr (Unk)
  • Pristiq (Unk)
This finding indicates that some patients can be more vulnerable to developing Zoloft side effects, such as Irritability.
Crying, Decreased Interest, Depressed Mood, Pain, Headache, Initial Insomnia, Disturbance In Attention, Irritability, Abdominal Discomfort

A patient from US was prescribed and started Zoloft on Oct 29, 2013. After Zoloft was administered, patient encountered several Zoloft side effects: crying, decreased interest, depressed mood, pain, headache, initial insomnia, disturbance in attention, irritability, abdominal discomfort Additional patient health information: male , 30 years of age, The consumer reported the following symptoms: . Zoloft dosage: Unk. Concurrently used drugs:
  • Effexor Xr (Unk)
  • Pristiq (Unk)
Decreased Interest, Irritability

This report suggests a potential Zoloft Irritability side effect(s) that can have serious consequences. A 30-year-old female patient from US (weight:NA) was diagnosed with the following health condition(s): NA and used Zoloft (dosage: Unk) starting NS. Soon after starting Zoloft the patient began experiencing various side effects, including:
  • Decreased Interest
  • Irritability
Drugs used concurrently:NA. Although Zoloft demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Irritability, may still occur.
Asthenia, Fatigue, Insomnia, Irritability, Abdominal Discomfort

An adverse event was reported by a consumer or non-health professional on Oct 29, 2013 by a Female taking Zoloft (dosage: Unk) . Location: US , 30 years of age, patient began experiencing various side effects, including: Patient felt the following Zoloft side effects: asthenia, fatigue, insomnia, irritability, abdominal discomfort. Additional medications/treatments:
Anxiety, Decreased Interest, Depressed Mood, Asthenia, Fatigue, Apathy, Insomnia, Irritability, Nervousness

This Irritability problem was reported by a consumer or non-health professional from US. A 30-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On NS a consumer started treatment with Zoloft (dosage: Unk). The following drugs/medications were being taken at the same time: NA. When commencing Zoloft, the patient experienced the following unwanted symptoms /side effects:
  • Anxiety
  • Decreased Interest
  • Depressed Mood
  • Asthenia
  • Fatigue
  • Apathy
  • Insomnia
  • Irritability
  • Nervousness
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Irritability, may become evident only after a product is in use by the general population.
Crying, Anxiety, Pain, Social Avoidant Behaviour, Feelings Of Worthlessness, Feeling Guilty, Irritability, Appetite Disorder, Restlessness

This is a Zoloft side effect report of a 30-year-old female patient (weight: NA) from US. The patient developed the following symptoms/conditions: NA and was treated with Zoloft (dosage: Unk) starting NS. Concurrently used drugs:
  • Effexor Xr (Unk)
Soon after that, the consumer experienced the following of symptoms:
  • Crying
  • Anxiety
  • Pain
  • Social Avoidant Behaviour
  • Feelings Of Worthlessness
  • Feeling Guilty
  • Irritability
  • Appetite Disorder
  • Restlessness
This opens a possibility that Zoloft could cause Irritability and that some female patients may be more susceptible.
Crying, Anxiety, Social Avoidant Behaviour, Irritability, Feeling Guilty, Tension, Restlessness, Dyspnoea

This Irritability side effect was reported by a consumer or non-health professional from US on Oct 25, 2013. A female patient from US , 30 years of age, was treated with Zoloft. Patient felt the following Zoloft side effects: crying, anxiety, social avoidant behaviour, irritability, feeling guilty, tension, restlessness, dyspnoea. Zoloft dosage: Unk. These side effects may potentially be related to Zoloft.
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DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Zoloft Irritability Causes and Reviews


For most adults, moderate alcohol use is probably not harmful. However, about 18 million adult Americans have an alcohol use disorder (AUD). This means that their drinking causes distress and harm. It includes alcoholism and alcohol abuse.

Alcoholism, or alcohol dependence, is a disease that causes

  • Craving - a strong need to drink
  • Loss of control - not being able to stop drinking once you've started
  • Physical dependence - withdrawal symptoms
  • Tolerance - the need to drink more alcohol to feel the same effect

With alcohol abuse, you are not physically dependent, but you still have a serious problem. The drinking may cause problems at home, work, or school. It may cause you to put yourself in dangerous situations, or lead to legal or social problems.

Another common problem is binge drinking. It is drinking about five or more drinks in two hours for men. For women, it is about four or more drinks in two hours.

Too much alcohol is dangerous. Heavy drinking can increase the risk of certain cancers. It can cause damage to the liver, brain, and other organs. Drinking during pregnancy can harm your baby. Alcohol also increases the risk of death from car crashes, injuries, homicide, and suicide.

You may have an AUD if you can answer yes to two or more of these questions:

In the past year, have you

  • Ended up drinking more or for a longer time than you had planned to?
  • Wanted to cut down or stop drinking, or tried to, but couldn't?
  • Spent a lot of your time drinking, or recovering from drinking?
  • Felt a strong need to drink?
  • Found that drinking - or being sick from drinking - often interfered with your family life, job, or school?
  • Kept drinking even though it was causing trouble with your family or friends?
  • Given up or cut back on activities that you enjoyed just so you could drink?
  • Gotten into dangerous situations while drinking or after drinking? Some examples are driving drunk and having unsafe sex.
  • Kept drinking even though it was making you feel depressed or anxious? Or when it was adding to another health problem?
  • Had to drink more and more to feel the effects of the alcohol?
  • Had withdrawal symptoms when the alcohol was wearing off? They include trouble sleeping, shakiness, Irritability, anxiety, depression, restlessness, nausea, and sweating. In severe cases, you could have a fever, seizures, or hallucinations.

If you have any of these symptoms, your drinking may already be a cause for concern. The more symptoms you have, the more serious the problem is. If you think you might have an AUD, see your health care provider for an evaluation. Your provider can help make a treatment plan, prescribe medicines, and if needed, give you treatment referrals.

NIH: National Institute on Alcohol Abuse and Alcoholism


Zoloft Irritability Reviews

Thu, 04 Mar 2010

Zoloft has been fantastic in helping with my anxiety issues. The biggest side effect I have noticed is an increase in bowel movements and constant thirst. Both side effects are tolerated because it helps me so much.

Fri, 24 Feb 2012

Overdose of Zoloft can cause severe reactions and serotonin syndrome is one of the life-threatening situations. Death can also result from Zoloft overdose. People who have lost someone due to Zoloft have filed a Zoloft lawsuit.

Sun, 28 Nov 2010

HORRIBLE stomach cramps. couldn't even walk. also, MAJOR diarhea.

Fri, 14 May 2010
Can Zoloft trigger Homicidal Ideation in a 10yr boy caught in the middle of hostile divorce?
Mon, 10 May 2010
I've been taking Zoloft for a number of years. I did not have any problems to begin with but now I have so many issues with bowel problems, terrible skin condition and am unable to lose weight. I have become gluten intolerant and various spices where once I could eat anything without any problems.
Thu, 25 Nov 2010
Jen - it's more likely you have PCOS than the Zoloft doing those things to you. Get checked out for that.
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Zoloft Side Effects

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Depression (561)
Insomnia (391)
Feeling Abnormal (378)
Atrial Septal Defect (376)
Dizziness (374)
Nausea (362)
Headache (337)
Fatigue (304)
Diarrhoea (253)
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Pain (224)
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Maternal Exposure During Pregnancy (151)
Confusional State (146)
Aggression (145)
Foetal Exposure During Pregnancy (143)
Vomiting (141)
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Abnormal Behaviour (139)
Irritability (138)
Hypertension (137)
Crying (137)
Malaise (133)
Suicide Attempt (129)
Weight Increased (126)
Nervousness (125)
Somnolence (125)
Loss Of Consciousness (119)
Panic Attack (112)
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Weight Decreased (108)
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Paraesthesia (93)
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