PAIN and Genteal


PAIN Symptoms and Causes

Pain is a signal in your nervous system that something may be wrong. It is an unpleasant feeling, such as a prick, tingle, sting, burn, or ache. Pain may be sharp or dull. It may come and go, or it may be constant. You may feel Pain in one area of your body, such as your back, abdomen, chest, pelvis, or you may feel Pain all over.

Pain can be helpful in diagnosing a problem. If you never felt Pain, you might seriously hurt yourself without knowing it, or you might not realize you have a medical problem that needs treatment.

There are two types of Pain: acute and chronic. Acute Pain usually comes on suddenly, because of a disease, injury, or inflammation. It can often be diagnosed and treated. It usually goes away, though sometimes it can turn into chronic Pain. Chronic Pain lasts for a long time, and can cause severe problems.

Pain is not always curable, but there are many ways to treat it. Treatment depends on the cause and type of Pain. There are drug treatments, including Pain relievers. There are also non-drug treatments, such as acupuncture, physical therapy, and sometimes surgery.

NIH: National Institute of Neurological Disorders and Stroke

Check out the latest treatments for PAIN

PAIN treatment research studies

Genteal clinical trials, surveys and public health registries

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Genteal Side Effects

Eye Irritation (30)
Eye Pain (25)
Vision Blurred (18)
Eye Pruritus (17)
Ocular Hyperaemia (16)
Pruritus (16)
Cataract (11)
Cataract Operation (9)
Eyelid Disorder (8)
Dry Eye (8)
Corneal Abrasion (7)
Lacrimation Increased (6)
Eye Swelling (6)
Foreign Body Sensation In Eyes (6)
Eye Infection (4)
Fall (4)
Hypersensitivity (4)
Weight Decreased (4)
Ulcerative Keratitis (3)
Instillation Site Pain (3)
Keratitis (3)
Corneal Disorder (3)
Visual Acuity Reduced (3)
Superficial Injury Of Eye (3)
Condition Aggravated (2)
Eye Operation (2)
Headache (2)
Cellulitis (2)
Anorexia (2)
Depression (2)
Eye Burns (2)
Furuncle (2)
Intraocular Pressure Increased (2)
Cerebrovascular Accident (2)
Eye Discharge (2)
Large Intestinal Obstruction Reduction (2)
Plastic Surgery (2)
Eye Inflammation (2)
Dyspnoea (2)
Diplopia (2)
Abnormal Sensation In Eye (2)
Conjunctival Ulcer (2)
Blepharospasm (2)
Anaphylactic Shock (2)
Visual Impairment (2)
Visual Disturbance (2)
Pneumonia (2)
Cataract Operation Complication (2)
Death (2)
Malaise (2)

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Common Meds

Abilify (10132)
Adderall (1304)
Amlodipine (6664)
Amoxicillin (4387)
Benadryl (1568)
Celebrex (12876 )
Celexa (1342)
Cialis (2975)
Cipro (8580)
Citalopram (7792)
Crestor (18839)
Cymbalta (14373)
Doxycycline (1757)
Effexor (7289)
Flexeril (435)
Flomax (2177)
Fluoxetine (4261)
Gabapentin (4593)
Hydrocodone (2469)
Ibuprofen (8222)
Lantus (10968)
Lexapro (3499)
Lipitor (17769)
Lisinopril (8919)
Lyrica (27148)
Medrol (650)
Mirena (41254)
Mobic (957)
Morphine (5356)
Naproxen (538)
Neurontin (6501)
Oxycodone (4438)
Pradaxa (13372)
Prednisone (5926)
Prilosec (2631)
Prozac (1954)
Seroquel (27216)
Simvastatin (8348)
Synthroid (4452)
Tamiflu (5585)
Topamax (3748)
Tramadol (5054)
Trazodone (1458)
Viagra (5394)
Vicodin (1153)
Wellbutrin (6324)
Xanax (2847)
Zocor (5718)

Recent Reviews

When I eat or drink this burning feeling in my chest going up like I am about vomiting.what is happening? And something I and chest pain too! And I am 14 and a girl

I am 12 weeks pregnant and last night i felt a pain on my lower right stomach trying to change the position i was sleeping and it was uncormfotable and very painful that i even screamed a little and after 2 minutes or so it went away and fa

When I press down on my stomach, in the lower right side in the pelvic region it hurts. Right by my hip bone. This has been going on for about a week. Could this be really bad? Im scared that I could be pregnant. but i dont think

<span style='color: #808080;'><b>Describe Your Neck pain from INFLUENZA (SEASONAL) (NO BRAND NAME) 2010 Experience Here:</b> Took 2010 flu shot on January 5, 2010. Fever ,chills and shaking 5 hours later. 12 hours late

22 years old my last period was july 7th 2011 and i have been intamate like almost every day. My period is due in 6 days...2 days ago i went to the bathrroom and wiped there was lite pink there, that was that. The next day the same happened. Now toda

60 years old, male. Left Nipple pain. Feels as though a piece of glass is right behind the nipple. It is very painful. Took a round of antibiotics and it didn't work. Had ultrasound done this morning and they said there is nothing there. Not to worry

A 40-year-old manager, at a prominent legal firm in L.A., experiences abdominal pain post lunch. He goes to the restroom a couple of times, but continues to experience pain and cramps. He eventually decides to get himself examined. While questioning

A rather large, painless bubble on my foreskin.

After 3 yrs still having worsening pain,popping of implant. Suspect may have been fracured in implantation. Wonder if any one else has had problems.

After becoming very ill, suffering much pain, losing weight and having many sleepless nights i was finally diagnosed with hoshimotos disease, subsequently i have hypothyroidism. I am only talking 50 mg oroxine 3 times a week and 100 mg the other 2 d

I took Beano (only one pill) last week and 2 hours later I ended up with a terrible stomach pain.I did not connect the dots, I suspected that it was caused by certain ingredients in the food I was eating. Itwas a very unique pain

Yesterday, after taking Sam-e with Glucosamine. I got a pain between my shoulder blade, jaw pain, dizziness, sweating. felt like a heart attack. I did not go to the hospital because of the money needed. No ins

<b><span style='font-weight: normal;'><b>After 6 weeks of oral lamisil I experienced</b>eczema, muscle weakness, asthma, bloody bowels, lower abdominal pain, dizziness, extreme f

63 yo man received Zostavax injection in the left upper arm 12/13/11. Developed painful blister on the right shoulder and pain at the right lower ribs 12/10/11.

After using Clobetasol for a two week cycle, my doctor suggested I use it one day during the week, applying it twice that day. Since that time, I have experinced severe chest pain. I recently saw my doctor for heart attack symptoms before I reali

Arthritis Treatment Safe, Natural Cure for Adults. Synflex Liquid Glucosamine, Rheumatoid Arthritis Joint Pain Relief Remedy, Diet Supplements. Synflex, Glucosamine for Dogs. Free Shipping! &lt;a href=''&g

My father is 68 and retired, he is also diabetic. He suffers from severe joints, hip and back pain. He has been using panadol extra strength but finds it takes too long to act. He is also allergic to aspirin and was hospitalized with a ruptured u

While taking Pradaxa I had severe knife feeling pain in left eye. I have been off 2 days and it is better. I will check with eye docotr this week and see if it is eye or meds.

Yes I am Aspavor 20mg and also have a back pain were I am constantly taking pain killers. I actually thought that I did some thing wrong by lifting but just from sitting or turning my body it will return it starts to effect my job off shore and h

i feel nick pain & headache i am ussed 9th month

PAIN Clinical Trials and Studies

Treatments might be new drugs or new combinations of drugs, new surgical procedures or devices, or new ways to use existing treatments. The goal of clinical trials is to determine if a new test or treatment works and is safe. Clinical trials can also look at other aspects of care, such as improving the quality of life for people with chronic illnesses. People participate in clinical trials for a variety of reasons. Healthy volunteers say they participate to help others and to contribute to moving science forward. Participants with an illness or disease also participate to help others, but also to possibly receive the newest treatment and to have the additional care and attention from the clinical trial staff.
Rank Status Study
1 Recruiting Improving Pain Management and Long Term Outcomes Following High Energy Orthopedic Trauma (Pain Study)
Condition: Pilon Fracture
Interventions: Drug: NSAID;   Drug: Gabapentinoids;   Drug: placebo
Outcome Measures: Opioid Utilization;   Persistent Pain;   Surgery for non-union;   Post Surgical Pain Intensity;   Pre Surgical Pain Intensity;   Length of Index Hospitalization;   Adverse Effects and Complications;   Functional Outcome;   Generic Health Status;   Depressive Symptoms;   Post Traumatic Stress (PTSD);   Medical Costs;   Fracture Severity;   Fracture Classification
2 Recruiting Literacy-Adapted Psychosocial Treatments for Chronic Pain --- "Learning About Mastering/My Pain"
Conditions: Chronic Pain;   Pain;   Widespread Chronic Pain;   Chronic Pain Syndrome;   Chronic Pain Due to Injury
Interventions: Behavioral: Pain Ed;   Behavioral: CBT for Pain;   Other: Usual Care
Outcome Measures: Brief Pain Inventory-Intensity (BPI-Intensity);   Brief Pain Inventory-Interference (BPI-Interference);   Patient Health Questionnaire - 9 (PHQ-9);   Patient Global Impression of Change (PGIC)
3 Recruiting A Multimodal Pain Pathway in Urogynecologic Surgery
Conditions: Pain;   Constipation;   Nausea
Intervention: Drug: Multimodal
Outcome Measures: Pain;   Pain;   Constipation
4 Unknown  Prevalence of Pain in Inpatient at the Hospital Italiano de Buenos Aires
Condition: Pain
Outcome Measures: Prevalence of Pain;   Response to analgesic treatment;   The cause of Pain during hospitalization;   Number of patients reporting Pain to heath care personnel;   Proportion of physicians who know the patient is in Pain according to the evolution in medical chart;   Number of nurses who know that the patient has Pain according to medical chart;   Proportion of hospitalized patients treated for Pain;   Type of analgesic treatment received;   Number of patients with Pain evaluated by a Pain specialist
5 Recruiting Pain - Postoperative Analgesia INvestigation
Condition: Postoperative Pain
Interventions: Drug: Exparel®;   Drug: Bupivacaine hydrochloride
Outcome Measures: Change in Postoperative Pain;   Overall opioid use;   Mean length of hospital stay;   Change from Baseline in Quality of Life
6 Recruiting Pain During Chest Tube Withdrawal: Evaluation Using Pan Monitor
Condition: Chest Pain
Interventions: Procedure: Chest drain withdrawal;   Device: Pain Monitor
Outcome Measures: Pain monitor evaluation of Pain;   Pain intensity
7 Recruiting Biomarkers for Pain in Spinal Cord Injury (SCI) Patients
Conditions: Traumatic Spinal Cord Injury;   Neuropathic Pain
Intervention: Other: blood samples
Outcome Measures: To identify candidate biomarkers for Pain in the chronic SCI samples.;   To identify the temporal relationship of the development of Pain and the manifestation of the biomarkers identified
8 Recruiting Neck Exercises, Training and Pain Management as a Treatment for Whiplash Patients With Chronic Neck Pain
Conditions: Neck Pain;   Chronic Pain Syndrome
Interventions: Other: Education and training;   Behavioral: Pain management
Outcome Measures: Medical Outcomes Study Short Form 36 (SF36) - Physical Component Summary (PCS);   craniocervical flexion test;   cervical range of motion;   neck positioning test;   Self-rated measure Global Perceived Effect;   Neck Disability Index;   Pain Bothersomeness;   Pain Specific Functioning Scale;   TAMPA scale of Kinesiophobia;   Impact of Event scale;   Euroqol-5D;   Mechanical allodynia
9 Not yet recruiting A Randomized-controlled Study of a Cognitive-behavioral Intervention for Children With Functional Abdominal Pain
Conditions: Functional Abdominal Pain Syndrome;   Abdominal Pain
Interventions: Behavioral: Intervention group;   Behavioral: Active control group
Outcome Measures: Change in Pain Symptoms;   Health-related quality of life;   Pain-related coping;   Pain-related cognitions
10 Not yet recruiting Effective Screening for Pain Study
Conditions: Pain;   Pain Management
Interventions: Behavioral: NRS Pain now;   Behavioral: PEG
Outcome Measures: Arm 1 (NRS now), to arm 2 (PEG), to arm 3 (usual care) pairwise difference scores in baseline and Pain disability detection at one week, and satisfaction with Pain management at one week;   Arm 1 (NRS now), to arm 2 (PEG), to arm 3 (usual care) pairwise differences in Pain missingness and rating variability;   Arm 1 (NRS now), to arm 2 (PEG), to arm 3 (usual care) pairwise difference scores in baseline and Pain disability detection at one week,
11 Recruiting The Underlying Mechanism of Spinal Manipulative Therapy and the Effect of Pain on Physical Outcome Measures
Conditions: Low Back Pain;   Degeneration of Lumbosacral Intervertebral Disc;   Muscle Weakness;   Spine Stiffness
Interventions: Other: SMT for low back Pain patients;   Other: Pain induction (optional)
Outcome Measures: Change of Modified Oswestry Low Back Pain Disability Index;   Change of 11-point Numeric Pain Rating Scale;   Change in Body Pain diagram;   Change in measurement of lumbar multifidus muscle thickness by rehabilitative ultrasound imaging;   Change of spinal stiffness testing by a mechanical indentation machine;   Electromyography of trunk muscles;   Magnetic resonance imaging of lumbar region;   Fear Avoidance Beliefs Questionnaire;   Change in Borg Category-Ratio Scale of Perceived Exertion;   Global Rating Of Change
12 Recruiting Lactobacillus Reuteri in Treatment of Functional Abdominal Pain and Chronic Constipation in Children
Conditions: Abdominal Pain;   Constipation - Functional
Interventions: Dietary Supplement: Administration of L.reuteri in children with abdominal Pain;   Dietary Supplement: Administration of placebo in children with abdominal Pain;   Dietary Supplement: Administration of L.reuteri in children with constipation;   Dietary Supplement: Administration of placebo in children with constipation
Outcome Measures: Intensity of abdominal Pain;   Severity of chronic constipation;   Intensity of abdominal Pain after treatment;   Severity of chronic constipation after treatment
13 Recruiting Post-market Study of Intrathecal Morphine Compared to Conventional Medical Management for Pain Control and Improvement of Opioid-related Side Effects
Conditions: Nonmalignant Pain;   Chronic Pain;   Chronic Intractable Pain
Intervention: Device: SynchroMed Infusion System and Intrathecal Morphine Sulfate
Outcome Measures: Clinical Success;   Pain Assessment;   Opioid-Related Side Effects
14 Recruiting Acupuncture in Acute Nonspecific Low Back Pain
Condition: Low Back Pain
Interventions: Procedure: Acupuncture and standard treatment in general practice;   Other: Standard treatment in general practice
Outcome Measures: Median time in days to recovery of Pain.;   Reduction in Pain;   Global measure of improvement;   Back specific functional status;   Sick leaves;   Use of medication;   Visits at the GP;   Side effects of treatment
15 Unknown  Bupivacaine Pain Pumps to Decrease Mastectomy Post-Operative Pain
Condition: Pain
Interventions: Drug: Bupivacaine;   Drug: Saline
Outcome Measures: Differences in post-operative static and moving Pain scores between patients randomized either to bupivacaine- (treatment) or saline- (placebo) filled, percutaneously-placed Pain pump analgesic administration for post-operative Pain control.;   Document long-term changes in QOL scores between patients randomized either to bupivacaine- (treatment) or saline- (placebo) filled, percutaneously-placed Pain pump analgesic administration for post-operative Pain control.
16 Recruiting Ketamine in Chronic Kid's PainKiCK Pain
Condition: Chronic Pain
Intervention: Drug: Ketamine
Outcome Measure: Dosage of ketamine that is most tolerable
17 Recruiting A Epidemiological Survey of Preoperative Pain Perception and Postoperative Pain in Chinese Population
Conditions: Pain;   Surgery
Outcome Measures: Pressure Pain threshold;   Pressure Pain tolerance;   PCA press frequency after operation;   Pain scores on visual analog scale after operation;   Opioid consumption dose after operation
18 Recruiting The Effect of an Inter-Disciplinary Program, Including MBSR, in Breast Cancer Survivors With Chronic Neuropathic Pain
Conditions: Breast Cancer;   Painful Neuropathy;   Chronic Pain;   Worries; Pain or Disability;   Quality of Life
Intervention: Behavioral: Mindfulness-Based Stress Reduction
Outcome Measures: Change from baseline in Pain-related disability, as measured by the Brief Pain Inventory - Pain Interference scale, at 3-month post-intervention.;   Change from baseline in neuropathic Pain intensity, as measured by the Neuropathic Pain Symptom Inventory, at 3 months post-intervention;   Change from baseline in Pain severity, as measured by the Brief Pain Inventory - Pain Severity scale, at 3 months post-intervention;   Change from baseline in mood states, as measured by the Profile of Mood States scale, at 3 months post-intervention;   Overall change in status from baseline, as measured by Patient Global Impression of Change scale, at 3 months post-intervention;   Change from baseline in stress, as measured by the Perceived Stress Scale, at 3 months post-intervention;   Change from baseline in depressive symptoms, as measured by the Patient Health Questionnaire - 9 scale, at 3 months post-intervention;   Change from baseline in Pain catastrophizing, as measured by the Pain Catastrophizing Scale, at 3 months post-intervention.;   Change from baseline in mindfulness, as measured by the Five Facet Mindfulness Questionnaire, at 3 months post-intervention.;   Change from baseline in quality of life, as measured by the Short-Form-12 Health Survey, at 3 months post-intervention.;   Change from pre-intervention in biomarkers of stress, as measured by hair cortisol levels, at 3 months post-intervention.;   Change from baseline in immune function, as measured by blood levels of interleukin-4, interleukin-6, interleukin-10, tumor necrosis factor - alpha, and C reactive protein, at 3 months post-intervention.;   Change from baseline in biomarkers of stress, as measured by telomere length, at 3 months post-intervention.;   Change from pre-intervention in neuronal health, as measured by white matter integrity, at 2 weeks post-intervention.;   Change from pre-intervention in brain areas associated with emotional regulation, as measured by blood flow in the brain seen in functional magnetic imaging, at 2 weeks post-intervention.;   Change from pre-intervention in brain structure, as measured by changes in structural volume different areas of the brain, at 2 weeks post-intervention.
19 Recruiting Characterizing the Role of Pain Sensitivity in Acute to Persistent Low Back Pain
Condition: Low Back Pain
Outcome Measures: Experimental Pain Threshold;   mRNA expression of Pain sensitivity genes
20 Recruiting Internet Intervention for Adolescents With Chronic Pain
Conditions: Chronic Pain;   Abdominal Pain;   Headache
Interventions: Behavioral: Online Behavioral Intervention;   Other: Education: Online Patient Education
Outcome Measures: Change in Activity Limitations from Baseline to Immediately Post-Treatment, 6-month follow-up, and 12-month follow-up;   Change in Pain from Baseline to Immediately Post-Treatment, 6-month follow-up, and 12-month follow-up;   Depression and Pain-specific anxiety;   Treatment Satisfaction;   Parental Response to Pain Behavior;   Sleep Quality;   Service Use;   Miscarried Helping