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Pain (37)
Severe Muscular-skeletal Pain (25)
Sever Bone Pain (12)
Back Pain Irritablility Leg Burning (6)
Burning Mouth (4)
Dry Skin On Soles (4)
Itching (4)
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Boniva Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 5448 

Hypertension, Arthralgia, Fracture Delayed Union, Fall, Mass, Intervertebral Disc Protrusion, Tendon Disorder, Spondylolisthesis, Obesity (8463380-6)
on Jun 18, 2012 Female from UNITED STATES , 64 years of age, weighting 207.2 lb, was diagnosed with
  • osteoporosis prophylaxis
and was treated with Boniva. Directly after, patient experienced the unwanted or unexpected Boniva side effects: hypertension, arthralgia, fracture delayed union, fall, mass, intervertebral disc protrusion, tendon disorder, spondylolisthesis, obesity. Boniva dosage: N/A.
Associated medications used:
  • Fosamax
  • Reclast
  • Fosamax
  • Fosamax
  • Fosamax
  • Fosamax
Patient was hospitalized and became disabled.

Contusion, Rib Fracture, Laceration, Fall (8463095-4)
Patient was taking Boniva. Patient felt the following Boniva side effects: contusion, rib fracture, laceration, fall on Jul 09, 2009 from UNITED STATES Additional patient health information: Female , 93 years of age, was diagnosed with
  • osteoporosis
and. Boniva dosage: N/A.

Stress Fracture (8463088-7)
Adverse event was reported on Mar 30, 2007 by a Female taking Boniva (Dosage: N/A) . Location: UNITED STATES , 42 years of age, After Boniva was administered, patient encountered several Boniva side effects: stress fracture.

Hand Fracture, Fall (8463087-5)
on Dec 21, 2011 Female from UNITED STATES , 88 years of age, was treated with Boniva. Directly after, patient experienced the unwanted or unexpected Boniva side effects: hand fracture, fall. Boniva dosage: N/A.


Dysphagia, Asthenia, Dyspepsia, Headache, Dysphonia, Hypersensitivity, Dyspnoea, Nausea, Choking Sensation (8463042-5)
on Dec 30, 2009 Female from UNITED STATES , weighting 95.02 lb, was diagnosed with
  • osteopenia
and was treated with Boniva. Patient felt the following Boniva side effects: dysphagia, asthenia, dyspepsia, headache, dysphonia, hypersensitivity, dyspnoea, nausea, choking sensation. Boniva dosage: Other Indication: Osteoporosis.
Multiple prescriptions taken:
  • Toprol-xl
  • Ativan


Fall, Wrist Fracture, Upper Limb Fracture (8463027-9)
Patient was taking Boniva. After Boniva was administered, patient encountered several Boniva side effects: fall, wrist fracture, upper limb fracture on Apr 13, 2010 from UNITED STATES Additional patient health information: Female , weighting 259.9 lb, was diagnosed with
  • osteopenia
and. Boniva dosage: Frequency:every 3 Monthly.
Multiple concurrent drugs taken:
  • Calcium
  • Tricor
  • Imitrex
  • Librax
  • Risperidone
  • Zocor
  • Depakote
  • Advair Diskus 100/50


Ligament Rupture, Alopecia, Fall (8463026-7)
Adverse event was reported on Apr 20, 2010 by a Female taking Boniva (Dosage: N/A) was diagnosed with
  • osteoporosis
  • thyroid disorder
and. Location: UNITED STATES , weighting 141.3 lb, Directly after, patient experienced the unwanted or unexpected Boniva side effects: ligament rupture, alopecia, fall.
Associated medications used:
  • Thyroid Tab
  • Potassium Acetate
  • Ascorbic Acid
  • Poly-iron
  • Pacerone
  • Coumadin
  • Folic Acid


Foot Fracture, Chest Discomfort, Pain In Extremity (8463025-5)
on Jul 21, 2010 Female from UNITED STATES , 58 years of age, was diagnosed with
  • osteoporosis
and was treated with Boniva. Patient felt the following Boniva side effects: foot fracture, chest discomfort, pain in extremity. Boniva dosage: N/A.
Multiple prescriptions taken:
  • Niacin
  • Os-cal +d


Wrist Fracture (8463024-3)
on Jul 15, 2010 Female from UNITED STATES , 86 years of age, was diagnosed with
  • osteoporosis
and was treated with Boniva. After Boniva was administered, patient encountered several Boniva side effects: wrist fracture. Boniva dosage: N/A.

Loose Tooth, Knee Arthroplasty, Implant Site Pain, Joint Arthroplasty, Hip Arthroplasty (8462920-0)
Patient was taking Boniva. Directly after, patient experienced the unwanted or unexpected Boniva side effects: loose tooth, knee arthroplasty, implant site pain, joint arthroplasty, hip arthroplasty on Nov 09, 2011 from UNITED STATES Additional patient health information: Female , 85 years of age, . Boniva dosage: N/A.

Eye Haemorrhage, Visual Acuity Reduced, Glaucoma (8459210-9)
Adverse event was reported on Jun 21, 2012 by a Female taking Boniva (Dosage: N/A) was diagnosed with
  • osteoporosis
and. Location: BRAZIL , weighting 114.6 lb, Patient felt the following Boniva side effects: eye haemorrhage, visual acuity reduced, glaucoma.

Palpitations, Arrhythmia, Nausea (8459056-1)
on Jun 18, 2012 Female from GERMANY , 74 years of age, was treated with Boniva. After Boniva was administered, patient encountered several Boniva side effects: palpitations, arrhythmia, nausea. Boniva dosage: 3 Mg/ml Prior To The Event Was On 19/mar/2012.
Multiple concurrent drugs taken:
  • Falithrom


Contusion, Breast Disorder Female, Open Wound, Amnesia, Ligament Sprain, Hyperlipidaemia, Gastrooesophageal Reflux Disease, Osteonecrosis Of Jaw, Bone Disorder (8457447-6)
on Jun 18, 2012 Female from UNITED STATES , 56 years of age, weighting 218.3 lb, was diagnosed with
  • osteoporosis
  • osteopenia
and was treated with Boniva. Directly after, patient experienced the unwanted or unexpected Boniva side effects: contusion, breast disorder female, open wound, amnesia, ligament sprain, hyperlipidaemia, gastrooesophageal reflux disease, osteonecrosis of jaw, bone disorder. Boniva dosage: N/A.
Associated medications used:
  • Fosamax
Patient was hospitalized and became disabled.

Dental Caries, Fistula, Nasal Septum Deviation, Impaired Healing, Pulmonary Oedema, Vasodilatation, Exostosis, Gastrointestinal Pain, Uterine Leiomyoma (8456563-2)
Patient was taking Boniva. Patient felt the following Boniva side effects: dental caries, fistula, nasal septum deviation, impaired healing, pulmonary oedema, vasodilatation, exostosis, gastrointestinal pain, uterine leiomyoma on Jun 11, 2012 from UNITED STATES Additional patient health information: Female , 55 years of age, weighting 99.21 lb, was diagnosed with
  • bone loss
and. Boniva dosage: N/A.
Multiple prescriptions taken:
  • Fosamax


Pelvic Pain, Musculoskeletal Pain (8456423-7)
Adverse event was reported on Jun 15, 2012 by a Female taking Boniva (Dosage: N/A) was diagnosed with
  • osteoporosis
and. Location: KOREA, REPUBLIC OF , 60 years of age, After Boniva was administered, patient encountered several Boniva side effects: pelvic pain, musculoskeletal pain. Patient was hospitalized.

Dyspnoea, Headache, Haematuria (8456422-5)
on Jun 19, 2012 Male from INDONESIA , 52 years of age, was treated with Boniva. Directly after, patient experienced the unwanted or unexpected Boniva side effects: dyspnoea, headache, haematuria. Boniva dosage: N/A. Patient was hospitalized.

Femur Fracture (8456308-6)
on Jun 08, 2012 Female from UNITED STATES , weighting 140.2 lb, was diagnosed with
  • osteoporosis
and was treated with Boniva. Patient felt the following Boniva side effects: femur fracture. Boniva dosage: N/A. Patient was hospitalized.

Spondylolisthesis, Femur Fracture (8456284-6)
Patient was taking Boniva. After Boniva was administered, patient encountered several Boniva side effects: spondylolisthesis, femur fracture on Jun 08, 2012 from UNITED STATES Additional patient health information: Female , weighting 130.1 lb, was diagnosed with
  • osteopenia
and. Boniva dosage: N/A.
Multiple concurrent drugs taken:
  • Felodipine
  • Maxzide (Dose: 50/75)
  • Quinapril
  • Terazosin Hcl
Patient was hospitalized.

Middle Insomnia, Myalgia, Movement Disorder, Arthralgia, Paraesthesia (8454900-6)
Adverse event was reported on Jun 15, 2012 by a Female taking Boniva (Dosage: N/A) was diagnosed with
  • osteoporosis
and. Location: UNITED STATES , weighting 108.0 lb, Directly after, patient experienced the unwanted or unexpected Boniva side effects: middle insomnia, myalgia, movement disorder, arthralgia, paraesthesia.

Breast Calcifications, Hyperlipidaemia, Sleep Disorder, Phlebolith, Electrocardiogram Abnormal, Fall, Stress Fracture, Hot Flush (8453626-2)
on Jun 13, 2012 Female from UNITED STATES , 57 years of age, weighting 134.5 lb, was diagnosed with
  • osteoporosis
  • hypothyroidism
and was treated with Boniva. Patient felt the following Boniva side effects: breast calcifications, hyperlipidaemia, sleep disorder, phlebolith, electrocardiogram abnormal, fall, stress fracture, hot flush. Boniva dosage: N/A.
Multiple prescriptions taken:
  • Synthroid
  • Fosamax
  • Alendronate Sodium
  • Fosamax
  • Fosamax
  • Fosamax
  • Alendronate Sodium
Patient was hospitalized and became disabled.

Tibia Fracture, Spinal Fracture, Femur Fracture, Hip Fracture (8451050-X)
on Jun 08, 2012 Female from UNITED STATES , weighting 128.1 lb, was treated with Boniva. After Boniva was administered, patient encountered several Boniva side effects: tibia fracture, spinal fracture, femur fracture, hip fracture. Boniva dosage: N/A.
Multiple concurrent drugs taken:
  • Fosamax
  • Folic Acid


Pneumonia, T-cell Lymphoma, Depression, Weight Decreased, Pancreatitis (8451014-6)
Patient was taking Boniva. Directly after, patient experienced the unwanted or unexpected Boniva side effects: pneumonia, t-cell lymphoma, depression, weight decreased, pancreatitis on Jun 13, 2012 from GERMANY Additional patient health information: Female , weighting 110.2 lb, was diagnosed with
  • osteoporosis
and. Boniva dosage: N/A.

(8448645-6)
Adverse event was reported on Jun 19, 2012 by a Male taking Boniva (Dosage: N/A) was diagnosed with
  • osteoporosis
and. Location: INDONESIA , 80 years of age, .

Femur Fracture (8448453-6)
on Jun 08, 2012 Female from UNITED STATES , 63 years of age, was diagnosed with
  • osteopenia
and was treated with Boniva. After Boniva was administered, patient encountered several Boniva side effects: femur fracture. Boniva dosage: N/A.

Scar, Pathological Fracture, Pain In Extremity, Stress Fracture, Low Turnover Osteopathy, Femur Fracture, Gait Disturbance, Walking Aid User (8447641-2)
on May 29, 2012 Female from UNITED STATES , 65 years of age, was diagnosed with
  • osteopenia
and was treated with Boniva. Directly after, patient experienced the unwanted or unexpected Boniva side effects: scar, pathological fracture, pain in extremity, stress fracture, low turnover osteopathy, femur fracture, gait disturbance, walking aid user. Boniva dosage: N/A.
Associated medications used:
  • Fosamax (Oral)
  • Actonel (Oral)
Patient was hospitalized.

Showing 1-25 of 5448 

Boniva Health Episodes

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Boniva Information

Alternative BONIVA Names:IBANDRONA

Active Ingredient: IBANDRONA

Boniva Dosage, Warnings, Usage.

Side Effects reported to FDA: 5448. View Boniva Adverse Reports

Boniva safety alerts: 2008 2007

Reported deaths: 239

Reported hospitalizations: 1530

Bisphosphonates (marketed as Actonel, Actonel+Ca, Aredia, Boniva, Didronel, Fosamax, Fosamax+D, Reclast, Skelid, and Zometa)

Audience: Pharmacists, other healthcare professionals

[Posted 01/07/2008] FDA informed healthcare professionals and patients of the possibility of severe and sometimes incapacitating bone, joint, and/or muscle (musculoskeletal) pain in patients taking bisphosphonates. Although severe musculoskeletal pain is included in the prescribing information for all bisphosphonates, the association between bisphosphonates and severe musculoskeletal pain may be overlooked by healthcare professionals, delaying diagnosis, prolonging pain and/or impairment, and necessitating the use of analgesics. The severe musculoskeletal pain may occur within days, months, or years after starting a bisphosphonates. Some patients have reported complete relief of symptoms after discontinuing the bisphosphonate, whereas others have reported slow or incomplete resolution. The risk factors for and incidence of severe musculoskeletal pain associated with bisphosphonates are unknown.

Healthcare professionals should consider whether bisphosphonate use might be responsible for severe musculoskeletal pain in patients who present with these symptoms and consider temporary or permanent discontinuation of the drug.

[January 07, 2008 - Drug Information page - FDA]

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