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Cymbalta Side Effects

PatientsVille

Common Cymbalta Side Effects


The most commonly reported Cymbalta side effects (click to view or check a box to report):

Nausea (1362)
Dizziness (1252)
Headache (900)
Feeling Abnormal (847)
Fatigue (734)
Depression (731)
Insomnia (721)
Anxiety (624)
Alanine Aminotransferase Increased (619)
Paraesthesia (558)
Hyperhidrosis (557)
Diarrhoea (546)
Aspartate Aminotransferase Increased (536)
Suicidal Ideation (503)
Hepatic Enzyme Increased (466)
Blood Pressure Increased (463)
Vomiting (431)
Loss Of Consciousness (427)
Fall (422)
Asthenia (420)

➢ More



If you or someone in your family has experienced a serious side effect to a health product, you are encouraged to report the experience to your health care professional (e.g. physician, pharmacist). You could also complete a copy of the side effect reporting form or report your side effect to FDA.

Cymbalta Side Effects Reported to FDA



Cymbalta Side Effect Report#9999309
Dysphagia, Nausea, Dizziness, Hallucination, Paraesthesia, Muscle Spasms, Chills, Pain
This is a report of a 33-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: neck pain,back pain, who was treated with Cymbalta (dosage: 1 Pill 1 Time Per Day, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Dysphagia, Nausea, Dizziness, Hallucination, Paraesthesia, Muscle Spasms, Chills, Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cymbalta treatment in female patients, resulting in Dysphagia side effect.
Cymbalta Side Effect Report#9999236
Lethargy, Myalgia, Headache, Nausea, Vomiting
This report suggests a potential Cymbalta Lethargy side effect(s) that can have serious consequences. A male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: NA and used Cymbalta (dosage: 30 Mg, Bid) starting
Oct 10, 2013. After starting Cymbalta the patient began experiencing various side effects, including: Lethargy, Myalgia, Headache, Nausea, VomitingAdditional drugs used concurrently: NA.The patient was hospitalized. Although Cymbalta demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Lethargy, may still occur.
Cymbalta Side Effect Report#9999142
Halo Vision, Aura, Impaired Work Ability, Dry Mouth, Dry Eye, Gait Disturbance, Hypertension
This Halo Vision problem was reported by a consumer or non-health professional from US. A 64-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: neuropathy peripheral,depression. On
Aug 01, 2009 this consumer started treatment with Cymbalta (dosage: 1 X Night). The following drugs were being taken at the same time: NA. When using Cymbalta, the patient experienced the following unwanted symptoms/side effects: Halo Vision, Aura, Impaired Work Ability, Dry Mouth, Dry Eye, Gait Disturbance, HypertensionAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Halo Vision, may become evident only after a product is in use by the general population.
Cymbalta Side Effect Report#9996293
Asthma, Off Label Use
This Asthma side effect was reported by a pharmacist from GB. A 40-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Cymbalta (drug dosage: 60 Mg, Qd), which was initiated on NS. Concurrently used drugs: NA..After starting to take Cymbalta the consumer reported adverse symptoms, such as: Asthma, Off Label UseThese side effects may potentially be related to Cymbalta. The patient was hospitalized.
Cymbalta Side Effect Report#9996194
Nightmare, Hypoaesthesia, Paraesthesia, Hyperhidrosis, Nausea, Feeling Cold, Pain
This is a report of a 42-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Cymbalta (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Nightmare, Hypoaesthesia, Paraesthesia, Hyperhidrosis, Nausea, Feeling Cold, Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cymbalta treatment in female patients, resulting in Nightmare side effect.
Cymbalta Side Effect Report#9995832
Dysphemia, Paraesthesia, Nausea, Anxiety, Emotional Distress, Weight Increased
This report suggests a potential Cymbalta Dysphemia side effect(s) that can have serious consequences. A 40-year-old male patient (weight: NA) from US was diagnosed with the following symptoms/conditions: depression and used Cymbalta (dosage: 1 Time Daily Once Daily Taken By Mouth) starting NS. After starting Cymbalta the patient began experiencing various side effects, including: Dysphemia, Paraesthesia, Nausea, Anxiety, Emotional Distress, Weight IncreasedAdditional drugs used concurrently: NA. Although Cymbalta demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Dysphemia, may still occur.
Cymbalta Side Effect Report#9995813
Deep Vein Thrombosis, Gallbladder Non-functioning, Depression, Pain, Memory Impairment
This Deep Vein Thrombosis problem was reported by a consumer or non-health professional from US. A 29-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: pain,ankylosing spondylitis. On
Sep 23, 2013 this consumer started treatment with Cymbalta (dosage: By Mouth). The following drugs were being taken at the same time: NA. When using Cymbalta, the patient experienced the following unwanted symptoms/side effects: Deep Vein Thrombosis, Gallbladder Non-functioning, Depression, Pain, Memory ImpairmentThe patient was hospitalized.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Deep Vein Thrombosis, may become evident only after a product is in use by the general population.
Cymbalta Side Effect Report#9995756
Product Substitution Issue
This Product Substitution Issue side effect was reported by a physician from US. A 50-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Cymbalta (drug dosage: 30 Mg Daily Oral?approx 1-2 Months), which was initiated on NS. Concurrently used drugs: NA..After starting to take Cymbalta the consumer reported adverse symptoms, such as: Product Substitution IssueThese side effects may potentially be related to Cymbalta.
Cymbalta Side Effect Report#9995754
Contusion, Abdominal Pain, Pain
This is a report of a 53-year-old patient (weight: NA) from US, suffering from the following health symptoms/conditions: NA, who was treated with Cymbalta (dosage: NA, start time: NS), combined with: NA. and developed a serious reaction and side effect(s): Contusion, Abdominal Pain, Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cymbalta treatment in patients, resulting in Contusion side effect.
Cymbalta Side Effect Report#9995101
Hyponatraemia, Pituitary Haemorrhage
This report suggests a potential Cymbalta Hyponatraemia side effect(s) that can have serious consequences. A 70-year-old female patient (weight: NA) from JP was diagnosed with the following symptoms/conditions: depression,constipation and used Cymbalta (dosage: 20 Mg, Bid) starting
Dec 03, 2013. After starting Cymbalta the patient began experiencing various side effects, including: Hyponatraemia, Pituitary HaemorrhageAdditional drugs used concurrently:
  • Magmitt (330 Mg, Tid)
Although Cymbalta demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Hyponatraemia, may still occur.
Cymbalta Side Effect Report#9995097
Delirium, Hyponatraemia, Confusional State, Muscle Twitching, Somnolence, Off Label Use
This Delirium problem was reported by a consumer or non-health professional from GB. A 71-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: neuralgia. On
Feb 07, 2014 this consumer started treatment with Cymbalta (dosage: 30 Mg, Each Evening). The following drugs were being taken at the same time:
  • Bendroflumethiazide (Unk)
  • Co-dydramol (Unk)
  • Durogesic (Unk)
  • Felodipine (Unk)
  • Irbesartan (Unk)
  • Levothyroxine (Unk)
  • Oramorph (Unk)
  • Pantoprazole (Unk)
When using Cymbalta, the patient experienced the following unwanted symptoms/side effects: Delirium, Hyponatraemia, Confusional State, Muscle Twitching, Somnolence, Off Label UseThe patient was hospitalized and became disabled.Although all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Delirium, may become evident only after a product is in use by the general population.
Cymbalta Side Effect Report#9995095
Hyponatraemia
This Hyponatraemia side effect was reported by a consumer or non-health professional from FR. A 76-year-old female patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Cymbalta (drug dosage: 60 Mg, Qd), which was initiated on
Dec 17, 2013. Concurrently used drugs:
  • Lyrica (150 Mg, Qd)
  • Rivotril (0.35 Ml (7 Drops), Qd)
  • Lipanthyl (160 Mg, Qd)
  • Amlor (5 Mg, Qd)
  • Debridat /00465201/ (Unk)
  • Doliprane (Unk)
.After starting to take Cymbalta the consumer reported adverse symptoms, such as: HyponatraemiaThese side effects may potentially be related to Cymbalta. The patient was hospitalized.
Cymbalta Side Effect Report#9991836
Stomatitis Necrotising, Sinusitis, Osteonecrosis, Tooth Loss, Mucosal Infection, Sinus Perforation, Cranial Nerve Disorder, Herpes Virus Infection, Oral Pain
This is a report of a 50-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: depression,affective disorder,anxiety,attention deficit/hyperactivity disorder, who was treated with Cymbalta (dosage: 30 Mg, Qd, start time: 201112), combined with: NA. and developed a serious reaction and side effect(s): Stomatitis Necrotising, Sinusitis, Osteonecrosis, Tooth Loss, Mucosal Infection, Sinus Perforation, Cranial Nerve Disorder, Herpes Virus Infection, Oral Pain after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cymbalta treatment in female patients, resulting in Stomatitis Necrotising side effect.
Cymbalta Side Effect Report#9988828
Pain, Hypertension, Dry Mouth
This report suggests a potential Cymbalta Pain side effect(s) that can have serious consequences. A 58-year-old female patient (weight: NA) from MX was diagnosed with the following symptoms/conditions: arthritis and used Cymbalta (dosage: NA) starting NS. After starting Cymbalta the patient began experiencing various side effects, including: Pain, Hypertension, Dry MouthAdditional drugs used concurrently: NA.The patient was hospitalized. Although Cymbalta demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Pain, may still occur.
Cymbalta Side Effect Report#9981072
Hepatitis, Dyspnoea, Diarrhoea
This Hepatitis problem was reported by a consumer or non-health professional from US. A 66-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On 2009 this consumer started treatment with Cymbalta (dosage: 60 Mg, Bid). The following drugs were being taken at the same time: NA. When using Cymbalta, the patient experienced the following unwanted symptoms/side effects: Hepatitis, Dyspnoea, DiarrhoeaAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Hepatitis, may become evident only after a product is in use by the general population.
Cymbalta Side Effect Report#9980836
Paresis, Dyspnoea, Myalgia, Blood Creatine Phosphokinase Increased, Gamma-glutamyltransferase Increased, Back Pain, Blood Alkaline Phosphatase Increased, Pain In Extremity, Hyperbilirubinaemia
This Paresis side effect was reported by a consumer or non-health professional from FR. A 70-year-old male patient (weight:NA) experienced the following symptoms/conditions: NA.The patient was prescribed Cymbalta (drug dosage: 30 Mg, Qd), which was initiated on 2013. Concurrently used drugs:
  • Flecaine (30 Mg, Qd)
  • Prednisone (10 Mg, Each Morning)
  • Oxycontin (30 Mg, Bid)
  • Oxinorm /00045603/ (10 Mg, Until 4 Daily)
  • Flecaine (150 Mg, Qd)
  • Inexium /01479302/ (20 Mg, Each Morning)
  • Heptamyl (Unk, Tid)
  • Tardyferon (Unk, Each Morning)
.After starting to take Cymbalta the consumer reported adverse symptoms, such as: Paresis, Dyspnoea, Myalgia, Blood Creatine Phosphokinase Increased, Gamma-glutamyltransferase Increased, Back Pain, Blood Alkaline Phosphatase Increased, Pain In Extremity, HyperbilirubinaemiaThese side effects may potentially be related to Cymbalta. The patient was hospitalized.
Cymbalta Side Effect Report#9980786
Stridor, Cough, Dysgeusia
This is a report of a 47-year-old female patient (weight: NA) from DE, suffering from the following health symptoms/conditions: neuralgia, who was treated with Cymbalta (dosage: 60 Mg, Qd, start time: 201311), combined with:
  • Pregabalin (150 Mg, Tid)
  • Amitriptylinoxide (60 Mg, Qd)
  • Tapentadol (100 Mg, Tid)
and developed a serious reaction and side effect(s): Stridor, Cough, Dysgeusia after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cymbalta treatment in female patients, resulting in Stridor side effect.
Cymbalta Side Effect Report#9972773
Completed Suicide
This report suggests a potential Cymbalta Completed Suicide side effect(s) that can have serious consequences. A 45-year-old female patient (weight: NA) from FR was diagnosed with the following symptoms/conditions: NA and used Cymbalta (dosage: NA) starting NS. After starting Cymbalta the patient began experiencing various side effects, including: Completed SuicideAdditional drugs used concurrently:
  • Zyprexa
Although Cymbalta demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Completed Suicide, may still occur.
Cymbalta Side Effect Report#9970011
Skin Wrinkling, Eye Swelling, Dry Skin, Yellow Skin, Skin Discolouration, Dry Skin
This Skin Wrinkling problem was reported by a consumer or non-health professional from MX. A 45-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: NA. On
Feb 13, 2014 this consumer started treatment with Cymbalta (dosage: 30 Mg, Qd). The following drugs were being taken at the same time: NA. When using Cymbalta, the patient experienced the following unwanted symptoms/side effects: Skin Wrinkling, Eye Swelling, Dry Skin, Yellow Skin, Skin Discolouration, Dry SkinAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Skin Wrinkling, may become evident only after a product is in use by the general population.
Cymbalta Side Effect Report#9960845
Dyspnoea, Tremor, Sleep Disorder, Mood Swings, Bipolar Disorder, Condition Aggravated
This Dyspnoea side effect was reported by a health professional from US. A 48-year-old female patient (weight:NA) experienced the following symptoms/conditions: bipolar i disorder.The patient was prescribed Cymbalta (drug dosage: 30 Mg ( 3 Tabs) A Few Weeks Am Po), which was initiated on NS. Concurrently used drugs: NA..After starting to take Cymbalta the consumer reported adverse symptoms, such as: Dyspnoea, Tremor, Sleep Disorder, Mood Swings, Bipolar Disorder, Condition AggravatedThese side effects may potentially be related to Cymbalta.
Cymbalta Side Effect Report#9960316
Gingivitis, Periodontitis
This is a report of a 35-year-old female patient (weight: NA) from FR, suffering from the following health symptoms/conditions: depression, who was treated with Cymbalta (dosage: NA, start time:
Dec 16, 2013), combined with: NA. and developed a serious reaction and side effect(s): Gingivitis, Periodontitis after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cymbalta treatment in female patients, resulting in Gingivitis side effect.
Cymbalta Side Effect Report#9949481
Malnutrition, Protein Deficiency
This report suggests a potential Cymbalta Malnutrition side effect(s) that can have serious consequences. A 46-year-old female patient (weight: NA) from US was diagnosed with the following symptoms/conditions: depression and used Cymbalta (dosage: 60 Mg, Tid) starting NS. After starting Cymbalta the patient began experiencing various side effects, including: Malnutrition, Protein DeficiencyAdditional drugs used concurrently: NA.The patient was hospitalized. Although Cymbalta demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Malnutrition, may still occur.
Cymbalta Side Effect Report#9949477
Blood Alkaline Phosphatase Increased
This Blood Alkaline Phosphatase Increased problem was reported by a consumer or non-health professional from JP. A 48-year-old female patient (weight: NA) was diagnosed with the following symptoms/conditions: depression. On NS this consumer started treatment with Cymbalta (dosage: 60 Mg, Qd). The following drugs were being taken at the same time: NA. When using Cymbalta, the patient experienced the following unwanted symptoms/side effects: Blood Alkaline Phosphatase IncreasedAlthough all drugs are carefully tested before they are licensed for use, they carry side effect risks. Some side effects, such as Blood Alkaline Phosphatase Increased, may become evident only after a product is in use by the general population.
Cymbalta Side Effect Report#9949273
Blood Pressure Increased
This Death side effect was reported by a consumer or non-health professional from JP. A 75-year-old male patient (weight:NA) experienced the following symptoms/conditions: depression.The patient was prescribed Cymbalta (drug dosage: 20 Mg, Qd), which was initiated on
Mar 25, 2011. Concurrently used drugs:
  • Lyrica (Unk)
  • Voltaren /00372302/
  • Tramadol Hydrochloride And Acetaminophen
  • Nicorandil (10 Mg, Unk)
  • Artist (2.5 Mg, Unk)
  • Nexium /01479302/ (20 Mg, Unk)
  • Clopidogrel Sulfate (75 Mg, Unk)
  • Warfarin Potassium (1 Df, Unk)
.After starting to take Cymbalta the consumer reported adverse symptoms, such as: Blood Pressure IncreasedThese side effects may potentially be related to Cymbalta.
Cymbalta Side Effect Report#9940641
Cataract, Presyncope, Abdominal Pain Upper, Vomiting, Diarrhoea, Influenza
This is a report of a 76-year-old female patient (weight: NA) from US, suffering from the following health symptoms/conditions: depression, who was treated with Cymbalta (dosage: 60 Mg, Qd, start time:
Feb 18, 2014), combined with: NA. and developed a serious reaction and side effect(s): Cataract, Presyncope, Abdominal Pain Upper, Vomiting, Diarrhoea, Influenza after the beginning of treatment. This case can indicate the possible existence of increased vulnerability to Cymbalta treatment in female patients, resulting in Cataract side effect.


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The appearance of Cymbalta on this list does not mean that FDA has concluded that the drug has the listed risk. It means that FDA has identified a potential safety issue, but it does not mean that FDA has found a causal relationship between the drug and the listed risk.


What are common Cymbalta Side Effects for Women?

Women Side EffectsReports
Nausea 1106
Dizziness 988
Headache 738
Feeling Abnormal 685
Fatigue 587
Insomnia 556
Depression 535
Anxiety 466
Diarrhoea 466
Alanine Aminotransferase Increased 450

What are common Cymbalta Side Effects for Men?

Men Side EffectsReports
Dizziness 253
Nausea 249
Depression 192
Alanine Aminotransferase Increased 168
Insomnia 163
Feeling Abnormal 160
Headache 158
Anxiety 155
Suicidal Ideation 150
Fatigue 145

Track Your Side Effects

Note Your Observations

It is really important to keep track of your health symptoms, right from the time you start a new medicine. You can do it any way you prefer: in a notebook, in a computer file or using our online tool. You should also note down any other medicines you are taking at the same time, because there could be an interaction between these medicines.

Why Your Notes are Important

Your notes could be helpful in several ways:

  • You can use them to remind you of details that may alert your health care professional(s) to a problem
  • You will have a record to refer to in the future, in case you are ever prescribed the same medicine again

  • Log Form

    You can use the following log form to write down important information, like the date and time you experienced a side effect and your symptoms, how strong the symptoms were, and any other medicines you were using.

    Medicine Name and Dosage:
    Side Effects Scale Date & Time Other Medicine(s) or Treatment(s)
    Scale: 1 = very mild to 10 = very bad

    Side effects reports are analyzed to discover potential health product safety signals. Some important reactions may take an extremely long time to develop or occur infrequently. Continued monitoring of adverse reactions is thus essential to maintain a comprehensive safety and effectiveness profile of health products.

    You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    Cymbalta reports list potential signals of serious risks and new safety information that were identified using the FDA Adverse Event Reporting System (FAERS).
    FAERS is a database that contains information on adverse event and medication errors reports submitted to FDA by healthcare professionals (such as physicians, pharmacists, nurses and others), consumers (such as patients, family members, layers and others) and manufacturers.

    Discuss Cymbalta Side Effects

    Did You Have a Cymbalta Side Effect?

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    How Effective is Cymbalta for You?

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    Cymbalta Safety Alerts, Active Ingredients, Usage Information

    NDC0002-3235
    TypeHUMAN PRESCRIPTION DRUG
    Proprietary NameCymbalta
    NameDuloxetine hydrochloride
    Dosage FormCAPSULE, DELAYED RELEASE
    RouteORAL
    On market since20040824
    LabelerEli Lilly and Company
    Active Ingredient(s)DULOXETINE HYDROCHLORIDE
    Strength(s)20
    Unit(s)mg/1
    Pharma ClassNorepinephrine Uptake Inhibitors [MoA],Serotonin and Norepinephrine Reuptake Inhibitor [EPC],Seroton

    Cymbalta Dosage, Warnings, Usage.

    Side Effects reported to FDA: 14373

    Cymbalta safety alerts: 2005

    Reported deaths: 928

    Reported hospitalizations: 4360

    Cymbalta (duloxetine) Public Health Advisory: Suicidality in Adults Being Treated with Antidepressant Medications

    Audience: Neuropsychiatric healthcare professionals and consumers

    [UPDATE 07/08/2005] FDA notified healthcare professionals about the availability of updated Healthcare Professional and Patient Information Sheets for antidepressant medications that were the subject of a June 30, 2005 Public Health Advisory issued about the risk of suicidality (suicidal thinking or behavior) in adults being treated with antidepressant medications.

    [Posted 07/01/2005] In response to recent scientific publications that report the possibility of increased risk of suicidal behavior in adults treated with antidepressants, the FDA has issued a Public Health Advisory to update patients and healthcare providers with the latest information on this subject. Even before the publication of these recent reports, FDA had already begun the process of reviewing available data to determine whether there is an increased risk of suicidal behavior in adults taking antidepressants. The Agency has asked manufacturers to provide information from their trials using an approach similar to that used in the evaluation of the risk of suicidal behavior in the pediatric population taking antidepressants. This effort will involve hundreds of clinical trials and may take more than a year to complete.

    [July 08, 2005 - Healthcare Professional and Patient Information Sheets - FDA]
    [June 30, 2005 - Public Health Advisory - FDA]
    [June 30, 2005 - Drug Information Page - FDA]

    Latest Cymbalta clinical trials