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METHOTREXATE Safety Reports

Total METHOTREXATE reports: 548.
METHOTREXATE FDA safety alerts: 2005 2006 .
Reported deaths: 162    Reported hospitalizations: 191.
Take METHOTREXATE Side Effects Survey or Share Your METHOTREXATE Story. Read More Here.

Showing 1-75 of 548 Next >

Health Professional from FINLAND reported METHOTREXATE problem on Feb 26, 2007. Female patient, child 9 years of age, was diagnosed with brain neoplasm malignant and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from FINLAND on Feb 26, 2007. Female patient, 16 years of age, was diagnosed with brain neoplasm malignant and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, ETOPOSIDE, CISPLATIN, CARBOPLATIN, CYTARABINE. Patient died.

Consumer or non-health professional from FINLAND reported METHOTREXATE problem on Feb 26, 2007. Female patient, child 2 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, MERCAPTOPURINE, PREDNISONE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from FINLAND on Feb 26, 2007. Male patient, child 2 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

Health Professional from FINLAND reported METHOTREXATE problem on Feb 26, 2007. Female patient, child 2 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from FINLAND on Feb 26, 2007. Male patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

Consumer or non-health professional from FINLAND reported METHOTREXATE problem on Feb 26, 2007. Female patient, child 3 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from FINLAND on Feb 26, 2007. Male patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

Health Professional from UNITED STATES reported METHOTREXATE problem on Mar 05, 2007. Male patient, 49 years of age, was diagnosed with b precursor type acute leukaemia, acute lymphocytic leukaemia, prophylaxis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: leukopenia, mucosal inflammation, rash maculo-papular. METHOTREXATE dosage: unknown. During the same period patient was treated with ETOPOSIDE, CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE SULPHATE, CYTARABINE, DEXAMETHASONE, TRIMETHOPRIM. Patient recovered.

METHOTREXATE problem was reported by a Health Professional from FINLAND on Mar 02, 2007. Female patient, child 2 years of age, was diagnosed with medulloblastoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. Patient died.

Consumer or non-health professional from FINLAND reported METHOTREXATE problem on Mar 02, 2007. Female patient, child 7 years of age, was diagnosed with medulloblastoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, ETOPOSIDE, CISPLATIN, CARBOPLATIN, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from FINLAND on Mar 02, 2007. Male patient, child 2 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

Consumer or non-health professional from FINLAND reported METHOTREXATE problem on Mar 02, 2007. Female patient, child 2 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, MERCAPTOPURINE, PREDNISONE. Patient died.

METHOTREXATE problem was reported by a Health Professional from FINLAND on Mar 02, 2007. Female patient, child 2 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

Consumer or non-health professional from FINLAND reported METHOTREXATE problem on Mar 02, 2007. Female patient, child 3 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from FINLAND on Mar 02, 2007. Male patient, child 4 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on Feb 20, 2007. Female patient, 40 years of age, weighting 127.9 lb, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: beta haemolytic streptococcal infection, brain abscess, cerebral infarction, intervertebral discitis, psoas abscess, sepsis. METHOTREXATE dosage: unknown. During the same period patient was treated with REMICADE, ADCAL, FOLIC ACID, ACETAMINOPHEN, RISEDRONATE, SANDOCAL, SULFASALAZINE, VOLTAREN. Patient was hospitalized. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from AUSTRALIA on Feb 21, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: areflexia, faecal incontinence, herpes simplex, leukaemia recurrent, loss of proprioception, myelopathy, nuclear magnetic resonance imaging abnormal, osteomyelitis, paralysis flaccid. METHOTREXATE dosage: 12 MG PER_CYCLE IT. During the same period patient was treated with CYTARABINE, CYCLOPHOSPHAMIDE, VINCRISTINE, DOXORUBICIN, DEXAMETHASONE. Patient died.

Consumer or non-health professional from AUSTRALIA reported METHOTREXATE problem on Feb 21, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bk virus infection, cerebral haemorrhage, cerebral infarction, haematuria, myelopathy, sepsis. METHOTREXATE dosage: unknown. During the same period patient was treated with CYTARABINE, CYCLOPHOSPHAMIDE, VINCRISTINE. Patient died.

METHOTREXATE problem was reported by a Health Professional from FINLAND on Mar 02, 2007. Male patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE, DOXORUBICIN, CYTARABINE, MERCAPTOPURINE, DAUNORUBICIN. Patient died.

Consumer or non-health professional from FINLAND reported METHOTREXATE problem on Mar 02, 2007. Male patient, child 5 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE SULPHATE, DOXORUBICIN, CYCLOPHOSPHAMIDE, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, MERCAPTOPURINE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Feb 21, 2007. Male patient, child 11 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Feb 21, 2007. Female patient, 16 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, ETOPOSIDE, CISPLATIN, CARBOPLATIN, CYCLOPHOSPHAMIDE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Feb 21, 2007. Male patient, 19 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CYTARABINE, MERCAPTOPURINE, CYCLOPHOSPHAMIDE, DAUNORUBICIN. Patient died.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Feb 21, 2007. Male patient, 15 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Feb 21, 2007. Female patient, child 9 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. Patient died.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Feb 21, 2007. Female patient, 15 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Feb 21, 2007. Female patient, child 11 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, PREDNISONE, MERCAPTOPURINE. Patient died.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Feb 21, 2007. Male patient, child 12 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Feb 21, 2007. Female patient, 13 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, CORTISONE ACETATE, DAUNORUBICIN, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, CYTARABINE. Patient died.

Health Professional from FRANCE reported METHOTREXATE problem on Mar 12, 2007. Female patient, 16 years of age, was diagnosed with bone sarcoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, hepatotoxicity, mucosal inflammation, nephropathy toxic, pyrexia, reversible posterior leukoencephalopathy syndrome. METHOTREXATE dosage: unknown. During the same period patient was treated with ETOPOSIDE, IFOSFAMIDE, FOLINIC ACID. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from on Mar 12, 2007. Female patient, 16 years of age, weighting 110.2 lb, was diagnosed with bone sarcoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: anaemia, blood creatinine increased, convulsion, haemodialysis, headache, hypertension, mucosal inflammation. METHOTREXATE dosage: unknown. During the same period patient was treated with ETOPOSIDE, IFOSFAMIDE. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on Mar 09, 2007. Female patient, 72 years of age, weighting 149.9 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cerebral infarction, syncope. METHOTREXATE dosage: 10 MG 1XW PO. During the same period patient was treated with OMEPRAZOLE, CELECOXIB, FOLIC ACID, ALENDRONATE, INFLIXIMAB. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from JAPAN on Mar 05, 2007. Female patient, 32 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, delusion, erythema, hallucination, visual, nuclear magnetic resonance imaging brain abnormal, pachymeningitis, pneumonia. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOSPORINE, BUSULFAN, CYCLOPHOSPHAMIDE. Patient recovered.

Consumer or non-health professional from UNITED STATES reported METHOTREXATE problem on Feb 28, 2007. Female patient, 30 years of age, was diagnosed with ovarian germ cell choriocarcinoma stage i and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: toxic skin eruption. METHOTREXATE dosage: 30 MG QD IV. During the same period patient was treated with FOLIC ACID. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 28, 2007. Female patient, 25 years of age, was diagnosed with abortion induced and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: folliculitis, toxic skin eruption. METHOTREXATE dosage: unknown. Patient recovered.

Consumer or non-health professional from UNITED STATES reported METHOTREXATE problem on Feb 28, 2007. Male patient, 46 years of age, was diagnosed with burkitt's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bacterial infection, pyrexia, toxic skin eruption. METHOTREXATE dosage: unknown. During the same period patient was treated with DOXORUBICIN, CYCLOPHOSPHAMIDE, ONCOVIN, PREDNISOLONE, FOLIC ACID. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from on Mar 13, 2007. Male patient, 49 years of age, was diagnosed with prophylaxis against graft versus host disease and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: mucosal inflammation, rash maculo-papular, recall phenomenon, white blood cell count decreased. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DEXAMETHASONE, VINCRISTINE, DOXORUBICIN, CYTARABINE, TRIMETHOPRIM, ETOPOSIDE. Patient recovered.

Health Professional from JAPAN reported METHOTREXATE problem on Mar 19, 2007. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: inappropriate antidiuretic hormone secretion. METHOTREXATE dosage: unknown. During the same period patient was treated with CYTARABINE, PREDNISOLONE. Patient recovered.

METHOTREXATE problem was reported by a Health Professional from FRANCE on Mar 19, 2007. Female patient, 16 years of age, weighting 110.2 lb, was diagnosed with bone sarcoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, haemodialysis, hepatotoxicity, mucosal inflammation, nephropathy toxic, pyrexia, reversible posterior leukoencephalopathy syndrome. METHOTREXATE dosage: unknown. During the same period patient was treated with ETOPOSIDE, IFOSFAMIDE, FOLINIC ACID. Patient recovered.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Mar 02, 2007. Male patient, 15 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, DAUNORUBICIN, CYTARABINE, CORTISON, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Mar 02, 2007. Male patient, 19 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, DAUNORUBICIN, CYTARABINE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE. Patient died.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Mar 02, 2007. Female patient, 15 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, DAUNORUBICIN, CYTARABINE, CORTISON, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Mar 02, 2007. Male patient, child 12 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioma, treatment related secondary malignancy. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, DAUNORUBICIN, CYTARABINE, CORTISON, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE. Patient died.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Mar 01, 2007. Female patient, child 11 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glioblastoma multiforme. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE, PREDNISONE. Patient died.

METHOTREXATE problem was reported by a Health Professional from UNITED KINGDOM on Mar 01, 2007. Female patient, 37 years of age, weighting 207.2 lb, was diagnosed with immunosuppression, rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: induration, staphylococcal abscess, subcutaneous abscess. METHOTREXATE dosage: 15 MG WEEKLY. During the same period patient was treated with REMICADE, AMPICILLIN, DICLOFENAC, FOLIC ACID, TRAMADOL, ORAL CONTRACEPTIVE. Patient recovered.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Mar 05, 2007. Female patient, 13 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cytology abnormal, glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, DAUNORUBICIN, CYTARABINE, CORTISON, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Mar 05, 2007. Female patient, 16 years of age, was diagnosed with brain neoplasm malignant and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cytology abnormal, glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, CYTARABINE, ETOPOSIDE, CISPLATIN, CARBOPLATIN, CYCLOPHOSPHAMIDE. Patient died.

Consumer or non-health professional from GERMANY reported METHOTREXATE problem on Mar 05, 2007. Male patient, child 11 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cytology abnormal, glioma. METHOTREXATE dosage: unknown. During the same period patient was treated with VINCRISTINE, DOXORUBICIN, DAUNORUBICIN, CYTARABINE, CORITSON, ASPARAGINASE, CYCLOPHOSPHAMIDE, MERCAPTOPURINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 06, 2007. Male patient, 68 years of age, was diagnosed with non-hodgkin's lymphoma, pneumonia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: bone marrow failure, renal impairment, stomatitis. METHOTREXATE dosage: 2800 MG FREQ UNK IV. During the same period patient was treated with ERTAPENEM, EPIRUBICIN, ETOPOSIDE, FOLINIC ACID, IFOSFAMIDE, MESNA, OMEPRAZOLE. Patient recovered.

Health Professional from JAPAN reported METHOTREXATE problem on Mar 26, 2007. Female patient, 53 years of age, was diagnosed with dermatomyositis, diabetes mellitus and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: pneumatosis intestinalis. METHOTREXATE dosage: unknown. During the same period patient was treated with PREDNISOLONE, METHYLPREDNISOLONE, VOGLIBOSE, INSULIN. Patient recovered.

METHOTREXATE problem was reported by a Pharmacist from UNITED STATES on Mar 23, 2007. Female patient, 64 years of age, was diagnosed with dehydration, hypokalaemia, pancytopenia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: pancytopenia. METHOTREXATE dosage: unknown. During the same period patient was treated with METHADONE, ESCITALOPRAM, METOPROLOL SUCCINATE, GABAPENTIN, ESOMEPRAZOLE MAGNESIUM, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from MALAYSIA reported METHOTREXATE problem on Mar 22, 2007. Male patient, 40 years of age, was diagnosed with hodgkin's disease and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: glasgow coma scale abnormal, meningeal disorder, myelitis transverse, myelopathy, paraplegia, respiratory distress, urinary retention. METHOTREXATE dosage: unknown. Patient died.

METHOTREXATE problem was reported by a Physician from INDIA on Mar 08, 2007. Male patient, 40 years of age, was diagnosed with lip and/or oral cavity cancer and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: dermatitis bullous, hypersensitivity, leukopenia, mucosal inflammation, pain in extremity, pyrexia, stomatitis, thrombocytopenia. METHOTREXATE dosage: 100 MG ONCE IV. Patient recovered.

Consumer or non-health professional from AUSTRALIA reported METHOTREXATE problem on Mar 22, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: areflexia, bk virus infection, cerebral haemorrhage, cerebral infarction, csf protein increased, febrile neutropenia, gastrointestinal haemorrhage, haematuria, no therapeutic response. METHOTREXATE dosage: 12 MG IT. During the same period patient was treated with CYTARABINE, IDARUBICIN, FLUDARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from GERMANY on Mar 12, 2007. Female patient, child 9 years of age, was diagnosed with brain neoplasm malignant and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: convulsion, glioma, intracranial pressure increased, nervous system disorder. METHOTREXATE dosage: unknown. Patient died.

Health Professional from UNITED KINGDOM reported METHOTREXATE problem on Mar 15, 2007. Female patient, 37 years of age, weighting 207.2 lb, was diagnosed with immunosuppression, rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: induration, staphylococcal abscess, subcutaneous abscess. METHOTREXATE dosage: 15 MG WEEKLY UNK. During the same period patient was treated with REMICADE, AMPICILLIN, DICLOFENAC, FOLIC ACID, TRAMADOL, ORAL CONTRACEPTIVE. Patient was hospitalized. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from on Mar 26, 2007. Female patient, 53 years of age, was diagnosed with dermatomyositis, diabetes mellitus and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: pneumatosis intestinalis, pneumomediastinum, pneumoperitoneum, subcutaneous emphysema. METHOTREXATE dosage: 7.5 MG WEEKLY. During the same period patient was treated with PREDNISOLONE, INSULIN, VOGLIBOSE. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from reported METHOTREXATE problem on Mar 26, 2007. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: blood osmolarity abnormal, depressed level of consciousness, fatigue, hyponatraemia, hypothalamo-pituitary disorder, inappropriate antidiuretic hormone secretion. METHOTREXATE dosage: 15 MG X 1 DOSE. During the same period patient was treated with PREDNISOLONE, CYTARABINE, IDARUBICIN, MITOXANTRONE. Patient was hospitalized. Patient recovered.

METHOTREXATE problem was reported by a Health Professional from AUSTRALIA on Apr 02, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cerebral infarction, haemorrhage, sepsis, spinal cord disorder. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, CYTARABINE, FLUDARABINE, IDARUBICIN, HEMATOPOETIC PROGENITOR CELLS. Patient died.

Health Professional from AUSTRALIA reported METHOTREXATE problem on Apr 02, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: atrophy, leukaemia recurrent, malignant neoplasm progression, myelopathy, osteomyelitis, sepsis, spinal cord disorder. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, DOXORUBICIN, DEXAMETHASONE, CYTARABINE, MERCAPTOPURINE. Patient died.

METHOTREXATE problem was reported by a Health Professional from AUSTRALIA on Apr 09, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cerebral infarction, haemorrhage, sepsis, spinal cord disorder. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, CYTARABINE, FLUDARABINE, IDARUBICIN, HEMATOPOETIC PROGENITOR CELLS. Patient died.

Health Professional from JAPAN reported METHOTREXATE problem on Apr 06, 2007. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: inappropriate antidiuretic hormone secretion. METHOTREXATE dosage: unknown. During the same period patient was treated with PREDNISOLONE, DAUNORUBICIN, MITOXANTRONE. Patient recovered.

METHOTREXATE problem was reported by a Health Professional from AUSTRALIA on Apr 09, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, osteomyelitis, sepsis, spinal cord disorder. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, DOXORUBICIN, DEXAMETHASONE, CYTARABINE, MERCAPTOPURINE. Patient died.

Consumer or non-health professional from FRANCE reported METHOTREXATE problem on Mar 22, 2007. Male patient, 16 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: renal colic. METHOTREXATE dosage: unknown. Patient was hospitalized. Patient recovered.

METHOTREXATE problem was reported by a Health Professional from UNITED STATES on Mar 23, 2007. Female patient, 15 years of age, was diagnosed with juvenile arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: anaemia, dizziness, gastric ulcer, gastritis, occult blood positive, tachycardia. METHOTREXATE dosage: 25 MG;WEEKLY;ORAL. During the same period patient was treated with PREDNISONE, FOLIC ACID, LANSOPRAZOLE, NAPROSYN. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from reported METHOTREXATE problem on Apr 05, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cerebral haemorrhage, cerebral infarction, febrile neutropenia, gastrointestinal haemorrhage, haematuria, hodgkin's disease recurrent, myelopathy, paralysis flaccid, sepsis. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DEXAMETHASONE, VINCRISTINE, DOXORUBICIN, CYTARABINE, IDARUBICIN, FLUDARABINE. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from on Apr 05, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: incontinence, leukaemia recurrent, myelopathy, osteomyelitis, paralysis flaccid, sensory loss, sepsis. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DEXAMETHASONE, MERCAPTOPURINE, VINCRISTINE, DOXORUBICIN, CYTARABINE, ANTIVIRAL TREATMENT, STEROID TREATMENT. Patient died.

Pharmacist from UNITED STATES reported METHOTREXATE problem on Mar 22, 2007. Female patient, 34 years of age, was diagnosed with rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: accidental overdose, diarrhoea, gastric infection, mouth ulceration, oedema peripheral, skin ulcer, vomiting, wound. METHOTREXATE dosage: unknown. During the same period patient was treated with ARAVA, PREDNISONE, ARCOXIA, LCD CREAM. Patient was hospitalized. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 09, 2007. Female patient, 48 years of age, weighting 160.0 lb, was diagnosed with psoriasis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: hepatic fibrosis, hepatic pain, hepatic steatosis. METHOTREXATE dosage: 10 MG A WEEK FOR 2 MONTH PO 7.5 MG WEEKLY FOR 4 MONTH PO. Patient recovered.

Consumer or non-health professional from JAPAN reported METHOTREXATE problem on Mar 30, 2007. Female patient, 32 years of age, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: acute graft versus host disease in skin, delusion, erythema, hallucination, visual, nuclear magnetic resonance imaging brain abnormal, pachymeningitis, pneumonia. METHOTREXATE dosage: unknown. During the same period patient was treated with SANDIMMUNE, BUSULFAN, CYCLOPHOSPHAMIDE. Patient recovered.

METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED STATES on Apr 02, 2007. Male patient, 25 years of age, was diagnosed with non-hodgkin's lymphoma, prophylaxis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cerebral infarction, febrile neutropenia, haemorrhage, myelopathy, sepsis, spinal cord disorder. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, DOXORUBICIN, VINCRISTINE, DEXAMETHASONE, CYTARABINE, FLUDARABINE, IDARUBICIN. Patient was hospitalized and became disabled. Patient died.

Consumer or non-health professional from UNITED STATES reported METHOTREXATE problem on Apr 02, 2007. Female patient, 26 years of age, was diagnosed with acute lymphocytic leukaemia and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: malignant neoplasm progression, myelopathy, osteomyelitis, sepsis, spinal cord disorder. METHOTREXATE dosage: unknown. During the same period patient was treated with CYCLOPHOSPHAMIDE, VINCRISTINE SULPHATE, DOXORUBICIN, DEXAMETHASONE, CYTARABINE, MERCAPTOPURINE. Patient was hospitalized and became disabled. Patient died.

METHOTREXATE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Mar 26, 2007. Female patient, 37 years of age, weighting 207.2 lb, was diagnosed with immunosuppression, rheumatoid arthritis and was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: extravasation, induration, staphylococcal infection, subcutaneous abscess. METHOTREXATE dosage: 15 MG WEEKLY. During the same period patient was treated with REMICADE, AMPICILLIN, DICLOFENAC, FOLIC ACID, TRAMADOL, ORAL CONTRACEPTIVE, FLOXACILLIN. Patient was hospitalized. Patient recovered.

Consumer or non-health professional from UNITED KINGDOM reported METHOTREXATE problem on Mar 26, 2007. Female patient, 72 years of age, weighting 149.9 lb, was treated with METHOTREXATE. After drug was administered, patient experienced the following problems/side effects: cerebral infarction, loss of consciousness, syncope. METHOTREXATE dosage: 10 MG WEEKLY PO. During the same period patient was treated with OMEPRAZOLE, CELECOXIB, FOLIC ACID, FOSAMAX, INFLIXIMAB. Patient recovered.

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