Paroxetine Safety Questions, Paroxetine Answers
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Paroxetine Safety Reports
Total Paroxetine reports: 616.Paroxetine FDA safety alerts: 2003 2004 2005 2006 .
Reported deaths: 49 Reported hospitalizations: 148.
Take Paroxetine Side Effects Survey or Share Your Paroxetine Story.
Reported Paroxetine Side Effects: anxiety, nausea, suicidal ideation, headache, intentional overdose, hyperhidrosis, somnolence, depression, aggression, insomnia, agitation.
Paroxetine Usage.
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Paroxetine Side Effects Report #5230929-6Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: depressed mood, depression, stress, suicidal ideation. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with FLUOXETINE, NEFAZODONE. Patient recovered.
Paroxetine Side Effects Report #5230931-4
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Female patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: abnormal dreams, anger, crying, feeling abnormal, insomnia, stress, suicidal ideation. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5230944-2
Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Female patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: condition aggravated, confusional state, delusion, depressed mood, dissociation, feeling abnormal, flashback, overdose. PAROXETINE dosage: 40MG PER DAY. During the same period patient was treated with AMITRIPTYLINE, ALCOHOL, DIAZEPAM, PREMPAK C. Patient recovered.
Paroxetine Side Effects Report #5230949-1
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Female patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, blood amylase increased, diarrhoea, vomiting. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5230950-8
Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: agitation, anger, depressed mood, depression, irritability. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5230951-X
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Female patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: suicidal ideation. PAROXETINE dosage: unknown. Patient recovered.
Paroxetine Side Effects Report #5230955-7
Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Female patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: asthenia, dizziness, gastrointestinal disorder, lethargy, nausea, palpitations, paraesthesia. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with AMITRIPTYLINE. Patient recovered.
Paroxetine Side Effects Report #5230965-X
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Female patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: anger, convulsion, disturbance in attention, fatigue, major depression, memory impairment, mood swings, poor quality sleep. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with CITALOPRAM, ST JOHNS WORT. Patient recovered.
Paroxetine Side Effects Report #5230975-2
Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, confusional state, disturbance in attention, headache, hyperventilation, ill-defined disorder, malaise, psychiatric symptom. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with TRAZODONE, ZOPICLONE, BENDROFLUAZIDE, MIRTAZAPINE, PROPRANOLOL. Patient recovered.
Paroxetine Side Effects Report #5230995-8
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Female patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: crying, suicidal ideation. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5231004-7
Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Male patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: suicidal ideation. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5231014-X
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Male patient was diagnosed with post-traumatic stress disorder and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: melaena, mood swings, panic attack, rectal haemorrhage. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with EPANUTIN, TRAMADOL. Patient recovered.
Paroxetine Side Effects Report #5231016-3
Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Male patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: anorexia, depressed mood, major depression, poor quality sleep, restless legs syndrome, thinking abnormal, weight decreased. PAROXETINE dosage: 30MG PER DAY. During the same period patient was treated with CHLORPROMAZINE. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5231023-0
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: anxiety, depression, suicidal ideation. PAROXETINE dosage: 30MG PER DAY. During the same period patient was treated with PROTHIADEN, FLUANXOL. Patient recovered.
Paroxetine Side Effects Report #5231025-4
Physician from UNITED KINGDOM reported PAROXETINE problem on Jan 31, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, physical assault, trance, weight increased. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5231040-0
PAROXETINE problem was reported by a Physician from UNITED KINGDOM on Jan 31, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, completed suicide, overdose, suicidal ideation. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5231098-9
Consumer or non-health professional from FRANCE reported PAROXETINE problem on Jan 29, 2007. Male patient, 69 years of age, was diagnosed with depression, sleep apnoea syndrome and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: blood osmolarity decreased, blood uric acid decreased, brugada syndrome, hyponatraemia, syncope. PAROXETINE dosage: 40MG PER DAY. During the same period patient was treated with TEGRETOL, RISPERDAL, AMLOR, SECTRAL. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5232530-7
PAROXETINE problem was reported by a Consumer or non-health professional from MEXICO on Feb 02, 2007. Female patient, 58 years of age, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: renal failure. PAROXETINE dosage: 20MG PER DAY. Patient was hospitalized. Patient died on 01/13/2007.
Paroxetine Side Effects Report #5232659-3
Physician from UNITED STATES reported PAROXETINE problem on Feb 06, 2007. Female patient, 17 years of age, weighting 110.0 lb, was diagnosed with major depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: depression, disease recurrence. PAROXETINE dosage: 20 MG 2 DAILY PO. Patient recovered.
Paroxetine Side Effects Report #5232823-3
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 06, 2007. Male patient, weighting 185.0 lb, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, anhedonia, apathy, balance disorder, chills, feeling abnormal, suicidal ideation. PAROXETINE dosage: unknown. Patient recovered.
Paroxetine Side Effects Report #5233355-9
Consumer or non-health professional from UNITED STATES reported PAROXETINE problem on Feb 06, 2007. Female patient, 28 years of age, weighting 253.0 lb, was diagnosed with anxiety and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: arrhythmia, cardiac disorder, chills, economic problem, feeling abnormal, hot flush, palpitations. PAROXETINE dosage: 30MG DAILT PO. Patient recovered.
Paroxetine Side Effects Report #5233692-8
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 05, 2007. Male patient, 53 years of age, was diagnosed with post-traumatic stress disorder and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: diarrhoea, electric shock, gastroenteritis, insomnia, tic, viral infection. PAROXETINE dosage: 30MG PER DAY. During the same period patient was treated with XANAX, CYMBALTA. Patient recovered.
Paroxetine Side Effects Report #5233710-7
Consumer or non-health professional from JAPAN reported PAROXETINE problem on Feb 02, 2007. Female patient, 73 years of age, was diagnosed with depression, parkinson's disease and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: blood creatine phosphokinase increased, depressed level of consciousness, hyperhidrosis, incontinence, muscle rigidity, neuroleptic malignant syndrome, pyrexia, tremor. PAROXETINE dosage: 10MG PER DAY. During the same period patient was treated with PRAMIPEXOLE DIHYDROCHLORIDE, CARBIDOPA AND LEVODOPA. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5238515-9
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 12, 2007. Male patient was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: melanocytic naevus, precancerous skin lesion. PAROXETINE dosage: 20MG PER DAY. Patient recovered.
Paroxetine Side Effects Report #5239206-0
Physician from ITALY reported PAROXETINE problem on Jan 30, 2007. Male patient, 77 years of age, was diagnosed with dementia and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: cardio-respiratory arrest, disseminated intravascular coagulation, hyperglycaemia, hyperosmolar state, metabolic alkalosis, neuroleptic malignant syndrome, pneumonia aspiration, renal failure, respiratory failure. PAROXETINE dosage: 20 MG, QD. During the same period patient was treated with CLOZAPINE. Patient was hospitalized. Patient died.
Paroxetine Side Effects Report #5239548-9
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 29, 2007. Male patient, 25 years of age, was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, alcohol use, amnesia, headache, homicide, hyperhidrosis, incorrect dose administered, nausea, nightmare. PAROXETINE dosage: unknown. During the same period patient was treated with ZOPICLONE, ALCOHOL. Patient recovered.
Paroxetine Side Effects Report #5240485-4
Consumer or non-health professional from UNITED STATES reported PAROXETINE problem on Feb 15, 2007. Female patient was diagnosed with panic disorder, depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: abdominal pain, anxiety, constipation, crying, depression, dry mouth, insomnia, suicidal ideation, weight increased. PAROXETINE dosage: 40MG PER DAY. During the same period patient was treated with WELLBUTRIN, HYDROCHLOROTHIAZIDE, DIOVAN, ATIVAN. Patient recovered.
Paroxetine Side Effects Report #5241478-3
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED STATES on Feb 14, 2007. Female patient, 59 years of age, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: depression, immobile, social avoidant behaviour, suicidal ideation, thrombosis. PAROXETINE dosage: 40MG PER DAY. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5241506-5
Consumer or non-health professional from FRANCE reported PAROXETINE problem on Feb 09, 2007. Female patient, 27 years of age, weighting 66.14 lb, was diagnosed with anxiety and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: alopecia, back pain, blood osmolarity decreased, constipation, decreased appetite, dehydration, disturbance in attention, hypoalbuminaemia, hypoglycaemia. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with LAROXYL, LEXOMIL. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5244208-4
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 15, 2007. Male patient, 60 years of age, was diagnosed with anxiety, hypertension and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: completed suicide, overdose. PAROXETINE dosage: unknown. During the same period patient was treated with METFORMIN, ASPIRIN, DIAZEPAM, PERINDOPRIL ERBUMINE, SALBUTAMOL, SIMVASTATIN. Patient died on 01/25/2007.
Paroxetine Side Effects Report #5244999-2
Consumer or non-health professional from FRANCE reported PAROXETINE problem on Feb 12, 2007. Male patient, 69 years of age, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: blood osmolarity decreased, blood sodium decreased, blood uric acid decreased, brugada syndrome, hyponatraemia, syncope. PAROXETINE dosage: 40 MG/DAY. During the same period patient was treated with RISPERDAL, AMLODIPINE, SECTRAL, TEGRETOL. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5245267-5
PAROXETINE problem was reported by a Physician from UNITED STATES on Feb 14, 2007. Female patient, 22 years of age, weighting 118.2 lb, was diagnosed with anxiety disorder and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: collapse of lung, completed suicide, disability, dissociation, endometriosis, hormone level abnormal, injury asphyxiation, insomnia, performance status decreased. PAROXETINE dosage: 10MG PER DAY. Patient died on 10/07/2003.
Paroxetine Side Effects Report #5246132-X
Consumer or non-health professional from FRANCE reported PAROXETINE problem on Feb 16, 2007. Female patient, 39 years of age, was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: cardiac failure, cardiogenic shock, circulatory collapse, cytolytic hepatitis, depressed level of consciousness, electrocardiogram st segment depression, electrocardiogram t wave amplitude decreased, haemodynamic instability, hyperlactacidaemia. PAROXETINE dosage: unknown. During the same period patient was treated with HYDROXYCHLOROQUINE SULPHATE, BROMAZEPAM, ZOLPIDEM. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5247000-X
PAROXETINE problem was reported by a Consumer or non-health professional from FRANCE on Feb 14, 2007. Female patient, 62 years of age, was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: dyskinesia, memory impairment. PAROXETINE dosage: unknown. During the same period patient was treated with ANAFRANIL, LEVOTHYROXINE, LEXOMIL, MIZOLLEN. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5247013-8
Consumer or non-health professional from FRANCE reported PAROXETINE problem on Feb 14, 2007. Female patient, 85 years of age, was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: eosinophilia, face oedema, rash maculo-papular, toxic skin eruption, urticaria. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with ALLOPURINOL, CHLORAMINOPHENE, EQUANIL, IMOVANE, FOZITEC. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5248108-5
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 21, 2007. Male patient, 50 years of age, was diagnosed with depression, insomnia and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: dyskinesia, muscle spasms, muscle twitching, myalgia, myotonia. PAROXETINE dosage: unknown. During the same period patient was treated with TRAZODONE, CHOLESTYRAMINE. Patient recovered.
Paroxetine Side Effects Report #5248647-7
Consumer or non-health professional from UNITED STATES reported PAROXETINE problem on Feb 26, 2007. Female patient, 36 years of age, weighting 200.0 lb, was diagnosed with anxiety, depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: hypoaesthesia. PAROXETINE dosage: 40 MG ONCE A DAY PO. Patient recovered.
Paroxetine Side Effects Report #5249849-6
PAROXETINE problem was reported by a Pharmacist from FRANCE on Feb 27, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: loss of consciousness. PAROXETINE dosage: unknown. During the same period patient was treated with ZYPREXA, TERCIAN, NORSET, DEPAMIDE, PRAZEPAM. Patient recovered.
Paroxetine Side Effects Report #5252838-9
Health Professional from UNITED KINGDOM reported PAROXETINE problem on Feb 14, 2007. Male patient, 60 years of age, weighting 213.2 lb, was diagnosed with depression, diabetes mellitus and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: completed suicide, overdose. PAROXETINE dosage: unknown. During the same period patient was treated with METFORMIN, ASPIRIN, DIAZEPAM, PERINDOPRIL ERBUMINE, SALBUTAMOL, SIMVASTATIN. Patient died on 01/25/2007.
Paroxetine Side Effects Report #5252840-7
PAROXETINE problem was reported by a Health Professional from JAPAN on Feb 12, 2007. Female patient, 73 years of age, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aspartate aminotransferase increased, blood lactate dehydrogenase increased, hyperhidrosis, incontinence, muscle rigidity, neuroleptic malignant syndrome, stupor, tremor. PAROXETINE dosage: unknown. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5254736-3
Consumer or non-health professional from UNITED STATES reported PAROXETINE problem on Feb 12, 2007. Male patient, weighting 6.60 lb, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: melanocytic naevus, wound infection. PAROXETINE dosage: 20 MG; QD; TRPL. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5255544-X
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 16, 2007. Male patient was diagnosed with anxiety, depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, condition aggravated, muscle twitching, nervousness, self-injurious ideation, suicidal ideation. PAROXETINE dosage: unknown. Patient recovered.
Paroxetine Side Effects Report #5255794-2
Consumer or non-health professional from UNITED KINGDOM reported PAROXETINE problem on Feb 16, 2007. Male patient was diagnosed with anxiety, obsessive-compulsive disorder and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, physical assault, trance, weight increased. PAROXETINE dosage: 20 MG;PO;QD. Patient recovered.
Paroxetine Side Effects Report #5253130-9
PAROXETINE problem was reported by a Physician from FRANCE on Feb 19, 2007. Male patient was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, confusional state, hypersomnia, hypertension, sudden onset of sleep. PAROXETINE dosage: 30MG PER DAY. During the same period patient was treated with MILLEPERTUIS, NEBILOX, HYPERIUM, OLMESARTAN MEDOXOMIL, HYDROCHLOROTHIAZIDE, AMLODIPINE, DOGMATIL, LYSANXIA. Patient recovered.
Paroxetine Side Effects Report #5253153-X
Health Professional from GERMANY reported PAROXETINE problem on Feb 28, 2007. Female patient, 47 years of age, was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: agitation, rhabdomyolysis, somnolence, suicide attempt. PAROXETINE dosage: 20MG SEE TEXT. During the same period patient was treated with PROMETHAZINE, AMITRIPTYLINE. Patient recovered.
Paroxetine Side Effects Report #5254278-5
PAROXETINE problem was reported by a Consumer or non-health professional from FRANCE on Feb 21, 2007. Female patient, 78 years of age, was diagnosed with depression, essential hypertension and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: asthenia, consciousness fluctuating, hyponatraemia, speech disorder. PAROXETINE dosage: unknown. During the same period patient was treated with DIGOXIN. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5255312-9
Consumer or non-health professional from NETHERLANDS reported PAROXETINE problem on Feb 26, 2007. Female patient, 57 years of age, weighting 143.3 lb, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: colon cancer. PAROXETINE dosage: 20MG PER DAY. During the same period patient was treated with FEROGRADUMET. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5255317-8
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 22, 2007. Female patient, 55 years of age, was diagnosed with anxiety and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aggression, anger, depressed mood, dizziness, dyskinesia, emotional disorder. PAROXETINE dosage: 20MG TWICE PER DAY. During the same period patient was treated with SOLPADOL. Patient recovered.
Paroxetine Side Effects Report #5256029-7
Health Professional from JAPAN reported PAROXETINE problem on Feb 23, 2007. Female patient, 73 years of age, was diagnosed with depression and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: aspartate aminotransferase increased, blood lactate dehydrogenase increased, gait disturbance, incontinence, neuroleptic malignant syndrome, stupor, tremor. PAROXETINE dosage: 10 MG/DAY. During the same period patient was treated with PRAMIPEXOLE DIHYDROCHLORIDE. Patient was hospitalized. Patient recovered.
Paroxetine Side Effects Report #5256266-1
PAROXETINE problem was reported by a Consumer or non-health professional from UNITED STATES on Mar 02, 2007. Male patient, 22 years of age, weighting 165.0 lb, was diagnosed with post-traumatic stress disorder, social phobia and was treated with PAROXETINE. After drug was administered, patient experienced the following problems/side effects: condition aggravated, depression, impaired work ability, post-traumatic stress disorder, restlessness, social phobia. PAROXETINE dosage: 30MG 1 TIMES DAILY PO. Patient recovered.
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Drug Information: Paroxetine
URL of this page: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a698032.html
(pa rox' e teen)IMPORTANT WARNING:
| A small number of children, teenagers, and young adults (up to 24 years of age) who took antidepressants ('mood elevators') such as paroxetine during clinical studies became suicidal (thinking about harming or killing oneself or planning or trying to do so). Children, teenagers, and young adults who take antidepressants to treat depression or other mental illnesses may be more likely to become suicidal than children, teenagers, and young adults who do not take antidepressants to treat these conditions. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Children younger than 18 years of age should not normally take paroxetine, but in some cases, a doctor may decide that paroxetine is the best medication to treat a child's condition.You should know that your mental health may change in unexpected ways when you take paroxetine or other antidepressants even if you are an adult over age 24. You may become suicidal, especially at the beginning of your treatment and any time that your dose is increased or decreased. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself, or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling asleep or staying asleep; aggressive behavior; irritability; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.Your healthcare provider will want to see you often while you are taking paroxetine, especially at the beginning of your treatment. Be sure to keep all appointments for office visits with your doctor.The doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with paroxetine. Read the information carefully and ask your doctor or pharmacist if you have any questions. You also can obtain the Medication Guide from the FDA website: http://www.fda.gov/cder/drug/antidepressants/antidepressants_MG_2007.pdf.No matter what your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. You should also talk about the risks and benefits of not treating your condition. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. This risk is higher if you or anyone in your family has or has ever had bipolar disorder (mood that changes from depressed to abnormally excited) or mania (frenzied, abnormally excited mood) or has thought about or attempted suicide. Talk to your doctor about your condition, symptoms, and personal and family medical history. You and your doctor will decide what type of treatment is right for you. |
Why is this medication prescribed?
Paroxetine tablets, suspension (liquid), and extended-release (long-acting) tablets are used to treat depression, panic disorder (sudden, unexpected attacks of extreme fear and worry about these attacks), and social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life). Paroxetine tablets and oral solution are also used to treat obsessive compulsive disorder (bothersome thoughts that won't go away and the need to perform certain actions over and over), generalized anxiety disorder (excessive worrying that is difficult to control), and posttraumatic stress disorder (disturbing psychological symptoms that develop after a frightening experience). Paroxetine extended-release tablets are also used to treat premenstrual dysphoric disorder (PMDD, physical and psychological symptoms that occur before the onset of the menstrual period each month). Paroxetine is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.
How should this medicine be used?
Paroxetine comes as a tablet, a suspension (liquid), and a controlled-release (long-acting) tablet to take by mouth. It is usually taken once daily in the morning or evening, with or without food. You may want to take paroxetine with food to stop it from upsetting your stomach. Take paroxetine at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take paroxetine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Shake the liquid well before each use to mix the medication evenly.
Swallow the extended-release and Pexeva® brand tablets whole; do not split, chew, or crush them.
Your doctor may start you on a low dose of paroxetine and gradually increase your dose, not more than once a week.
Paroxetine controls your condition but does not cure it. It may take several weeks or longer before you feel the full benefit of paroxetine. Continue to take paroxetine even if you feel well. Do not stop taking paroxetine without talking to your doctor. Your doctor will probably decrease your dose gradually. If you suddenly stop taking paroxetine, you may experience withdrawal symptoms such as depression; mood changes; frenzied or abnormally excited mood; irritability; anxiety; confusion; dizziness; headache; tiredness; numbness or tingling in the arms, legs, hands, or feet; unusual dreams; difficulty falling asleep or staying asleep; nausea; or sweating. Tell your doctor if you experience any of these symptoms when your dose of paroxetine is decreased.
Other uses for this medicine
Paroxetine is also sometimes used to treat chronic headaches, tingling in the hands and feet caused by diabetes, and certain male sexual problems. Paroxetine is also used with other medications to treat bipolar disorder (mood that changes from depressed to abnormally excited ). Talk to your doctor about the possible risks of using this drug for your condition.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking paroxetine,
- tell your doctor and pharmacist if you are allergic to paroxetine or any other medications.
- tell your doctor if you are taking monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or have stopped taking them within the past 2 weeks, or if you are taking thioridazine or pimozide (Orap). Your doctor will probably tell you not to take paroxetine. If you stop taking paroxetine, you should wait at least 2 weeks before you start to take an MAO inhibitor.
- tell your doctor and pharmacist what other prescription and nonprescription medications, and vitamins you are taking or plan to take. Be sure to mention any of the following: anticoagulants ('blood thinners') such as warfarin (Coumadin); antidepressants (mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); antihistamines; aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn); atomoxetine (Straterra), atazanavir (Reyataz); bromocriptine (Parlodel); bupropion (Wellbutrin); buspirone (Buspar); celecoxib (Celebrex); chlorpromazine (Thorazine); cimetidine (Tagamet); clopidogrel (Plavix); codeine (found in many cough and pain medications); dexamethasone (Decadron); dextromethorphan (found in many cough medications); diazepam (Valium); dicloxacillin (Dynapen); digoxin (Lanoxin); dipyridamole (Persantine); diuretics ('water pills'); haloperidol (Haldol); isoniazid (INH, Nydrazid); lithium (Eskalith, Lithobid); medications for irregular heartbeat such as amiodarone (Cordarone, Pacerone), encainide (Enkaid), flecainide (Tambocor), mexiletine (Mexitil), moricizine (Ethmozine): propafenone (Rythmol), and quinidine (Quinidex); medications for mental illness and nausea; medications for migraine headaches such as almotriptan (Axert), eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), and zolmitriptan (Zomig);medications for seizures such as phenobarbital and phenytoin (Dilantin); meperidine (Demerol); methadone (Dolophine); metoclopramide (Reglan); metoprolol (Lopressor, Toprol XL); ondansetron (Zofran); other selective serotonin reuptake inhibitors such as citalopram (Celexa), fluoxetine (Prozac, Sarafem); fluvoxamine (Luvox); and sertraline (Zoloft); procyclidine (Kemadrin); propoxyphene (Darvon); propranolol (Inderal); ranitidine (Zantac); rifampin (Rifadin, Rimactane); risperidone (Risperdal); ritonavir (Norvir); sibutramine (Meridia); tamoxifen (Nolvadex); terbinafine (Lamisil); theophylline (Theobid, Theo-Dur); ticlopidine (Ticlid); timolol (Blocadren); tramadol (Ultram); trazodone (Desyrel); and venlafaxine (Effexor). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor what herbal products and nutritional supplements you are taking, especially St. John's wort and tryptophan.
- tell your doctor if you use or have ever used street drugs or have overused prescription medications, if you have recently had a heart attack, and if you have or have ever had glaucoma (an eye disease); seizures; bleeding from your stomach or esophagus (tube that connects the mouth and stomach) or liver, kidney, or heart disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking paroxetine, call your doctor.
- you should know that paroxetine may make you drowsy and affect your judgment and thinking. Do not drive a car or operate machinery until you know how this medication affects you.
- ask your doctor about the safe use of alcoholic beverages while you are taking paroxetine.
What special dietary instructions should I follow?
Unless your doctor tells you otherwise, continue your normal diet.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Paroxetine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- headache
- dizziness
- weakness
- difficulty concentrating
- nervousness
- forgetfulness
- confusion
- sleepiness or feeling "drugged"
- nausea
- vomiting
- diarrhea
- constipation
- gas
- stomach pain
- heartburn
- changes in ability to taste food
- decreased appetite
- weight loss or gain
- changes in sex drive or ability
- dry mouth
- sweating
- yawning
- sensitivity to light
- runny nose
- cough
- lump or tightness in throat
- pain in the back, muscles, joints, or anywhere in the body
- muscle weakness or tightness
- flushing
- problems with teeth
- unusual dreams
- painful or irregular menstruation
Some side effects can be serious. If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your doctor immediately:
- blurred vision
- rapid, pounding, or irregular heartbeat
- chest pain
- seizure
- abnormal bleeding or bruising
- sore throat, fever, chills, and other signs of infection
- uncontrollable shaking of a part of the body
- sudden muscle twitching or jerking that you cannot control
- numbness or tingling in your hands, feet, arms, or legs
- difficult, frequent, or painful urination
- swelling, itching, burning, or infection in the vagina
- painful erection that lasts for hours
- sudden upset stomach, vomiting, weakness, cramping, bloating, swelling, tightness in hands and feet, dizziness, headache and/or confusion
- hives
- skin rash
- itching
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
- hoarseness
- difficulty breathing or swallowing
- black and tarry stools
- red blood in stools
- bloody vomit
- vomiting material that looks like coffee grounds
Paroxetine may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/index.html] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Symptoms of overdose may include:
- drowsiness
- coma
- upset stomach
- uncontrollable shaking of a part of the body
- fast, pounding, irregular, or slow heartbeat
- confusion
- vomiting
- dizziness
- seizures
- fainting
- blurred vision
- extreme tiredness
- unusual bruising or bleeding
- lack of energy
- loss of appetite
- pain in the upper right part of the stomach
- flu-like symptoms
- yellowing of the skin and eyes
- aggressive behavior
- muscle pain, stiffness or weakness
- sudden muscle twitching or jerking that you cannot control
- dark red or brown urine
- difficulty urinating
- diarrhea
- frenzied, abnormally excited mood
- sweating
- fever
- difficulty walking
What other information should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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