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Glucose (6)
Low Platlet (4)
Severe Tiredness (4)
Weight Gain (4)
Pulmonary Hypertension (3)
Cellulitis (2)
Chills (2)
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Rebif Side Effects and Adverse Effects reported to US Food and Drug Administration (FDA)

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Showing 1-25 of 16230 

Fluid Retention, Tooth Disorder, Fatigue, Weight Decreased, Influenza Like Illness, Anaemia, Retinal Vascular Occlusion, Headache, Functional Gastrointestinal Disorder (8459510-2)
on Jun 14, 2012 Female from UNITED STATES , weighting 105.8 lb, was treated with Rebif. Directly after, patient experienced the unwanted or unexpected Rebif side effects: fluid retention, tooth disorder, fatigue, weight decreased, influenza like illness, anaemia, retinal vascular occlusion, headache, functional gastrointestinal disorder. Rebif dosage: N/A.
Associated medications used:
  • Hyzaar
  • Atenolol
  • Fosamax
  • Synthroid
  • Lisinopril
  • Oxybutynin Cl Er


Blood Glucose Increased, Pneumonia, Abdominal Discomfort, Hysterectomy, Peptic Ulcer, Hernia, Pain, Sinusitis, Pyrexia (8459508-4)
Patient was taking Rebif. Patient felt the following Rebif side effects: blood glucose increased, pneumonia, abdominal discomfort, hysterectomy, peptic ulcer, hernia, pain, sinusitis, pyrexia on Jun 14, 2012 from UNITED STATES Additional patient health information: Female , weighting 167.6 lb, . Rebif dosage: N/A.
Multiple prescriptions taken:
  • Ibuprofen


Normal Newborn, Multiple Sclerosis Relapse (8459489-3)
Adverse event was reported on Jun 14, 2012 by a Female taking Rebif (Dosage: N/A) was diagnosed with
  • multiple sclerosis
and. Location: UNITED STATES , weighting 224.9 lb, After Rebif was administered, patient encountered several Rebif side effects: normal newborn, multiple sclerosis relapse.

Balance Disorder, Fatigue, Injection Site Erythema, Injection Site Pain, Feeling Hot, Gait Disturbance (8459486-8)
on Jun 14, 2012 Female from UNITED STATES , weighting 180.8 lb, was treated with Rebif. Directly after, patient experienced the unwanted or unexpected Rebif side effects: balance disorder, fatigue, injection site erythema, injection site pain, feeling hot, gait disturbance. Rebif dosage: N/A.


Brain Operation, Intervertebral Disc Protrusion, Injection Site Pain, Injection Site Haematoma, Injection Site Erythema (8459485-6)
on Jun 14, 2012 Female from UNITED STATES , weighting 163.1 lb, was treated with Rebif. Patient felt the following Rebif side effects: brain operation, intervertebral disc protrusion, injection site pain, injection site haematoma, injection site erythema. Rebif dosage: N/A.
Multiple prescriptions taken:
  • Hydrocodone
  • Celexa
  • Hydroxyzine


Visual Acuity Reduced, Peroneal Nerve Palsy, Diabetes Mellitus, Multiple Sclerosis, Fall, Back Pain (8459484-4)
Patient was taking Rebif. After Rebif was administered, patient encountered several Rebif side effects: visual acuity reduced, peroneal nerve palsy, diabetes mellitus, multiple sclerosis, fall, back pain on Jun 14, 2012 from UNITED STATES Additional patient health information: Male , weighting 194.0 lb, . Rebif dosage: N/A.

Injection Site Discolouration, Injection Site Induration, Injection Site Haematoma, Multiple Sclerosis Relapse, Influenza Like Illness (8458223-0)
Adverse event was reported on Jun 14, 2012 by a Male taking Rebif (Dosage: N/A) was diagnosed with
  • multiple sclerosis
and. Location: UNITED STATES , weighting 145.5 lb, Directly after, patient experienced the unwanted or unexpected Rebif side effects: injection site discolouration, injection site induration, injection site haematoma, multiple sclerosis relapse, influenza like illness. Patient was hospitalized.

Gait Disturbance, Fatigue, Balance Disorder, Feeling Hot, Soft Tissue Necrosis, Injection Site Erythema, Injection Site Pain (8456673-X)
on Jun 07, 2012 Female from UNITED STATES , weighting 180.8 lb, was treated with Rebif. Patient felt the following Rebif side effects: gait disturbance, fatigue, balance disorder, feeling hot, soft tissue necrosis, injection site erythema, injection site pain. Rebif dosage: N/A.

Hypertension (8450704-9)
on Jun 13, 2012 Female from UNITED STATES , weighting 156.5 lb, was diagnosed with
  • multiple sclerosis
  • depression
and was treated with Rebif. After Rebif was administered, patient encountered several Rebif side effects: hypertension. Rebif dosage: 44 Ug, 3x/week.
Multiple concurrent drugs taken:
  • Paxil (20 Mg, Daily)
  • Lipitor (Unk, Daily)
  • Atorvastatin Calcium (10 Mg, Daily)
  • Lipitor (20 Mg, Daily)


Multiple Sclerosis Relapse, Injection Site Discolouration, Nausea, Cholecystectomy, Injection Site Erythema (8450130-2)
Patient was taking Rebif. Directly after, patient experienced the unwanted or unexpected Rebif side effects: multiple sclerosis relapse, injection site discolouration, nausea, cholecystectomy, injection site erythema on Jun 12, 2012 from UNITED STATES Additional patient health information: Female , weighting 119.0 lb, was diagnosed with
  • multiple sclerosis
and. Rebif dosage: N/A.

Injection Site Erythema, Colonic Polyp (8450112-0)
Adverse event was reported on Jun 11, 2012 by a Male taking Rebif (Dosage: N/A) . Location: UNITED STATES , weighting 141.1 lb, Patient felt the following Rebif side effects: injection site erythema, colonic polyp.

Neoplasm (8450111-9)
on Jun 11, 2012 Female from UNITED STATES , weighting 160.9 lb, was diagnosed with
  • multiple sclerosis
and was treated with Rebif. After Rebif was administered, patient encountered several Rebif side effects: neoplasm. Rebif dosage: N/A.

Neutrophil Count Decreased (8449876-1)
on Jun 14, 2012 Female from POLAND , weighting 125.7 lb, was treated with Rebif. Directly after, patient experienced the unwanted or unexpected Rebif side effects: neutrophil count decreased. Rebif dosage: N/A.
Associated medications used:
  • Fluoxemerck 20 Mg
  • Ambrosol
  • Ketoprofen
  • Solu-medrol
  • Ketoconazolum
  • Nystatin
  • Cladribine
  • Albuterol


Fatigue, Urticaria, Balance Disorder, Weight Increased, Injection Site Induration, Optic Neuritis, Insomnia, Sensory Disturbance, Dyspnoea (8449871-2)
Patient was taking Rebif. Patient felt the following Rebif side effects: fatigue, urticaria, balance disorder, weight increased, injection site induration, optic neuritis, insomnia, sensory disturbance, dyspnoea on Jun 13, 2012 from GERMANY Additional patient health information: Female , 48 years of age, . Rebif dosage: N/A.

Migraine (8449860-8)
Adverse event was reported on Jun 11, 2012 by a Female taking Rebif (Dosage: N/A) was diagnosed with
  • multiple sclerosis
and. Location: FRANCE , weighting 185.2 lb, After Rebif was administered, patient encountered several Rebif side effects: migraine.
Multiple concurrent drugs taken:
  • Desogestrel And Ethinyl Estradiol
  • Venlafaxine Hcl
  • Zopiclone


Injection Site Pain, Cardiac Septal Defect, Injection Site Haematoma (8448973-4)
on Jun 07, 2012 Female from UNITED STATES , weighting 110.2 lb, was diagnosed with
  • multiple sclerosis
and was treated with Rebif. Directly after, patient experienced the unwanted or unexpected Rebif side effects: injection site pain, cardiac septal defect, injection site haematoma. Rebif dosage: N/A.

Injection Site Erythema, Injection Site Swelling, Abdominal Hernia Repair, Influenza Like Illness, Nausea (8448866-2)
on Jun 11, 2012 Female from UNITED STATES , weighting 130.1 lb, was treated with Rebif. Patient felt the following Rebif side effects: injection site erythema, injection site swelling, abdominal hernia repair, influenza like illness, nausea. Rebif dosage: N/A.

Urinary Incontinence, Loss Of Consciousness, Injection Site Erythema, Head Injury (8448859-5)
Patient was taking Rebif. After Rebif was administered, patient encountered several Rebif side effects: urinary incontinence, loss of consciousness, injection site erythema, head injury on Jun 11, 2012 from UNITED STATES Additional patient health information: Male , weighting 222.7 lb, was diagnosed with
  • multiple sclerosis
and. Rebif dosage: N/A.
Multiple concurrent drugs taken:
  • Provigil
  • Provigil
  • Prinivil
  • Multiple Vitamin
  • Vitamin D


Thrombocytopenia, Systemic Lupus Erythematosus, Fibromyalgia, Arthralgia (8447562-5)
Adverse event was reported on Jun 11, 2012 by a Female taking Rebif (Dosage: N/A) was diagnosed with
  • multiple sclerosis
and. Location: UNITED STATES , weighting 110.2 lb, Directly after, patient experienced the unwanted or unexpected Rebif side effects: thrombocytopenia, systemic lupus erythematosus, fibromyalgia, arthralgia.

Injection Site Reaction, Blood Potassium Decreased, Multiple Sclerosis, Convulsion (8447558-3)
on Jun 11, 2012 Female from UNITED STATES , weighting 160.9 lb, was diagnosed with
  • multiple sclerosis
  • burning sensation
and was treated with Rebif. Patient felt the following Rebif side effects: injection site reaction, blood potassium decreased, multiple sclerosis, convulsion. Rebif dosage: N/A.
Multiple prescriptions taken:
  • Elavil
  • Fiorinal
  • Neurontin
  • Morphine
  • Lasix
  • Baclofen
  • Verapamil
  • Diazepam
Patient was hospitalized.

Weight Decreased, Diabetes Mellitus (8447557-1)
on Jun 11, 2012 Female from UNITED STATES , weighting 134.5 lb, was diagnosed with
  • multiple sclerosis
and was treated with Rebif. After Rebif was administered, patient encountered several Rebif side effects: weight decreased, diabetes mellitus. Rebif dosage: N/A.

Myocardial Infarction, Femoral Artery Occlusion, Pain In Extremity (8447548-0)
Patient was taking Rebif. Directly after, patient experienced the unwanted or unexpected Rebif side effects: myocardial infarction, femoral artery occlusion, pain in extremity on Jun 14, 2012 from UNITED STATES Additional patient health information: Female , weighting 125.7 lb, was diagnosed with
  • relapsing-remitting multiple sclerosis
  • pain
and. Rebif dosage: N/A.
Associated medications used:
  • Ibuprofen
Patient was hospitalized.

Splenic Abscess, Endocarditis, Gastrointestinal Disorder, Headache, Upper Respiratory Tract Infection, Injection Site Pruritus (8443859-3)
Adverse event was reported on Jun 09, 2012 by a Female taking Rebif (Dosage: N/A) was diagnosed with
  • multiple sclerosis
  • depression
  • band sensation
  • muscle spasms
and. Location: UNITED STATES , weighting 141.1 lb, Patient felt the following Rebif side effects: splenic abscess, endocarditis, gastrointestinal disorder, headache, upper respiratory tract infection, injection site pruritus.
Multiple prescriptions taken:
  • Pristiq
  • Gabapentin
  • Baclofen
Patient was hospitalized.

Thyroid Cancer (8443771-X)
on Jun 12, 2012 Female from GREECE , 58 years of age, was diagnosed with
  • multiple sclerosis
and was treated with Rebif. After Rebif was administered, patient encountered several Rebif side effects: thyroid cancer. Rebif dosage: N/A. Patient was hospitalized.

Benign Ovarian Tumour, Intervertebral Disc Operation, Injection Site Erythema, Headache, Injection Site Scar, Injection Site Pain (8442755-5)
on Jun 04, 2012 Female from UNITED STATES , weighting 136.7 lb, was diagnosed with
  • relapsing-remitting multiple sclerosis
and was treated with Rebif. Directly after, patient experienced the unwanted or unexpected Rebif side effects: benign ovarian tumour, intervertebral disc operation, injection site erythema, headache, injection site scar, injection site pain. Rebif dosage: N/A. Patient was hospitalized.

Showing 1-25 of 16230 

Rebif Health Episodes

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It is very important to keep track of all side effects and discuss them with your doctor. If you think you may have a medical emergency, call your doctor or 911 immediately.

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Most drugs have a large list of nonsevere or mild adverse effects which do not rule out continued usage. These effects depend on individual sensitivity, and can include nausea, dizziness, diarrhea, malaise, vomiting, headache, dermatitis, dry mouth, etc. Check commonly reported side effects . These can be considered a form of pseudo-allergic reaction, as not all users experience these effects; many users experience none at all.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Rebif Information

Alternative REBIF Names:INTERFERO

Active Ingredient: INTERFERO

More About Rebif

Side Effects reported to FDA: 16230. View Rebif Adverse Reports

Rebif safety alerts: No

Reported deaths: 713

Reported hospitalizations: 8523

Managing Your Medicines

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