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Spironolactone Renal Impairment Side Effects

Spironolactone Renal Impairment Side Effect Reports


The following Spironolactone Renal Impairment side effect reports were submitted by healthcare professionals and consumers.

This information will help you understand how side effects, such as Renal Impairment, can occur, and what you can do about them.

A side effect could appear soon after you start Spironolactone or it might take time to develop.



Pain, Fatigue, Chills, Rhinorrhoea, Productive Cough, Vision Blurred, Renal Impairment, Dyspnoea Exertional

This Renal Impairment side effect was reported by a pharmacist from US. A 64-year-old patient (weight:NA) experienced the following symptoms/conditions: cardiac failure congestive,hypertension,diabetes mellitus. The patient was prescribed Spironolactone (dosage: NA), which was started on Nov 30, 2003. Concurrently used drugs:
  • Lisinopril
  • Lisinopril
When starting to take Spironolactone the consumer reported the following symptoms:
  • Pain
  • Fatigue
  • Chills
  • Rhinorrhoea
  • Productive Cough
  • Vision Blurred
  • Renal Impairment
  • Dyspnoea Exertional
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Intentional Overdose, Suicide Attempt, Altered State Of Consciousness, Lactic Acidosis, White Blood Cell Count Increased, Renal Impairment, Hyperkalaemia

This Renal Impairment Spironolactone side effect was reported by a physician from JP on Jan 16, 2014. A male , 39 years of age, was treated with Spironolactone. The patient presented the following health conditions:
  • Intentional Overdose
  • Suicide Attempt
  • Altered State Of Consciousness
  • Lactic Acidosis
  • White Blood Cell Count Increased
  • Renal Impairment
  • Hyperkalaemia
. Spironolactone dosage: NA. Additional drugs used at the same time:
  • Metformin Hydrochloride
  • Pioglitazone
  • Sitagliptin Phosphate
  • Candesartan
  • Bisoprolol
  • Gabapentin
  • Paroxetine
The patient was hospitalized.
Product Name Confusion, Hyperkalaemia, Renal Impairment, Dry Skin

This is a Spironolactone side effect report of a 60-year-old female patient (weight:NA) from GB, suffering from the following symptoms/conditions: depression, who was treated with Spironolactone (dosage:50 Mg, 1x/day, start time: Apr 13, 2008), combined with:
  • Aspirin (75 Mg, 1x/day)
  • Amlodipine (10 Mg, 1x/day)
  • Fenofibrate (200 Mg, 1x/day)
  • Simvastatin (40mg Once Daily At Night)
  • Bumetanide (2mg Once Daily Every Morning)
  • Novomix (Unk)
  • Co-codamol (30/500)
  • Irbesartan (150 Mg, 1x/day)
, and developed a serious reaction and a Renal Impairment side effect. The patient presented with:
  • Product Name Confusion
  • Hyperkalaemia
  • Renal Impairment
  • Dry Skin
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from depression, resulting in Renal Impairment.

Lactic Acidosis, Blood Lactic Acid Increased, Blood Ph Decreased, Blood Bicarbonate Decreased, Blood Potassium Increased, Renal Impairment, Dysuria, Blood Urea Increased, Blood Creatinine Increased

A 70-year-old patient (weight: NA) from FI with the following symptoms: coronary artery disease started Spironolactone treatment (dosage: NA) on NS. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Lactic Acidosis
  • Blood Lactic Acid Increased
  • Blood Ph Decreased
  • Blood Bicarbonate Decreased
  • Blood Potassium Increased
  • Renal Impairment
  • Dysuria
  • Blood Urea Increased
  • Blood Creatinine Increased
. Concurrently used drugs:
  • Furosemide
  • Metformin
  • Etoricoxib
  • Ace Inhibitor Nos
The patient was hospitalized. This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Renal Impairment.
Renal Impairment, Blood Creatinine Increased

A patient from UNITED KINGDOM was prescribed and started Spironolactone on Apr 24, 2012. Patient felt the following Spironolactone side effects: renal impairment, blood creatinine increased Additional patient health information: male , 83 years of age, The consumer reported the following symptoms: was diagnosed with and. Spironolactone dosage: 25 Mg, Qd. Concurrently used drugs:
  • Bisoprolol Fumarate
  • Levothyroxine Sodium
  • Aspirin
  • Simvastatin
  • Lansoprazole
  • Nitroglycerin
  • Furosemide (40 Mg, Bid)
  • Ramipril (2.5 Mg, Qd)
The patient was hospitalized.
Gout, Hypomagnesaemia, Hypocalcaemia, Diarrhoea, Renal Impairment, Flank Pain

This report suggests a potential Spironolactone Renal Impairment side effect(s) that can have serious consequences. A 77-year-old patient from NETHERLANDS (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: NA) starting May 11, 2010. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • Gout
  • Hypomagnesaemia
  • Hypocalcaemia
  • Diarrhoea
  • Renal Impairment
  • Flank Pain
Drugs used concurrently:
  • Metoprolol Tartrate
  • Finasteride
  • Prednisolone
  • Furosemide
  • Oxazepam
  • Midazolam Hcl
  • Digoxin
  • Atorvastatin Calcium
Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Renal Impairment, may still occur.
Renal Impairment

An adverse event was reported by a health professional on Feb 24, 2012 by a male taking Spironolactone (dosage: 25 Mg, Unk) was diagnosed with and. Location: GERMANY , 79 years of age, weighting 242.5 lb, patient began experiencing various side effects, including: Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: renal impairment. Additional medications/treatments:
Associated medications used:
  • Ramipril (5 Mg, Bid)
  • Bicanorm (1 G, Unk)
  • Amlodipine (5 Mg, Unk)
  • Lorzaar (100 Mg, Unk)
  • Allopurinol (100 Mg, Unk)
  • Actos (15 Mg, Unk)
  • Simvabeta (20 Mg, Unk)
The patient was hospitalized.
Renal Injury, Anxiety, Renal Impairment, Emotional Distress, Multi-organ Failure, Renal Failure

This Renal Impairment problem was reported by a consumer or non-health professional from UNITED STATES. A 76-year-old patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Jan 21, 2005 a consumer started treatment with Spironolactone (dosage: Unk). The following drugs/medications were being taken at the same time:
  • Trasylol
  • Norvasc
  • Trasylol (200 Ml X 2, Unk)
  • Synthroid
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Renal Injury
  • Anxiety
  • Renal Impairment
  • Emotional Distress
  • Multi-organ Failure
  • Renal Failure
Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Renal Impairment, may become evident only after a product is in use by the general population.
Hyperkalaemia, Renal Impairment

This is a Spironolactone side effect report of a 61-year-old patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: cardiac failure congestive and was treated with Spironolactone (dosage: 50 Mg Every Day Po) starting Sep 14, 2010. Concurrently used drugs: NA. Soon after that, the consumer experienced the following of symptoms:
  • Hyperkalaemia
  • Renal Impairment
The patient was hospitalized. This opens a possibility that Spironolactone could cause Renal Impairment and that some patients may be more susceptible.
Pyrexia, Headache, Renal Impairment, Blood Glucose Increased

This Renal Impairment side effect was reported by a pharmacist from JAPAN on Aug 04, 2011. A female patient from JAPAN , 51 years of age, weighting 149.9 lb, was treated with Spironolactone. Directly after treatment started, patient experienced the unwanted or unexpected Spironolactone side effects: pyrexia, headache, renal impairment, blood glucose increased. Spironolactone dosage: 25 Mg, Unk.
Associated medications used:
  • Rasilez (150 Mg, Daily)
  • Rezaltas Combination
  • Crestor (2.5 Mg, Unk)
  • Levothyroxine Sodium (75 Mg, Unk)
  • Equa (50 Mg, Unk)
  • Digoxin (0.25 Mg, Unk)
  • Aspirin (100 Mg, Unk)
  • Allopurinol (200 Mg, Unk)
The patient was hospitalized. These side effects may potentially be related to Spironolactone.
Rhabdomyolysis, Renal Impairment, Hyperkalaemia, Pain, Oedema Peripheral

This Renal Impairment side effect was reported by a health professional from . A 80-year-old patient (weight:NA) experienced the following symptoms/conditions: NA. The patient was prescribed Spironolactone (dosage: NA), which was started on NS. Concurrently used drugs:
  • Bisoprolol Fumarate
  • Simvastatin (40 Mg (40 Mg, 1 In 1 D))
  • Bumetanide
  • Aspirin
  • Heparin
  • Insulin (insulin)
  • Ranitidine
  • Valsartan
When starting to take Spironolactone the consumer reported the following symptoms:
  • Rhabdomyolysis
  • Renal Impairment
  • Hyperkalaemia
  • Pain
  • Oedema Peripheral
These side effects may potentially be related to Spironolactone.
Renal Injury, Stress, Anxiety, Renal Failure, Fear, Renal Impairment, Unevaluable Event, Anhedonia

This Renal Impairment Spironolactone side effect was reported by a physician from UNITED STATES on Jun 06, 2009. A Female , 69 years of age, weighting 185.2 lb, was treated with Spironolactone. The patient presented the following health conditions:
  • Renal Injury
  • Stress
  • Anxiety
  • Renal Failure
  • Fear
  • Renal Impairment
  • Unevaluable Event
  • Anhedonia
. Spironolactone dosage: 25mg. Additional drugs used at the same time:
  • Cardizem (120mg Daily)
  • Coumadin (2.5mg-no Pill Sundays)
  • Captopril (Unk)
  • Coreg (0.25mg ? Tab Bid)
  • Trasylol (, Loading Dose Of 200ml, Then 50cc Per Hour Drip)
  • Insulin (Unk)
  • Acetylsalicylic Acid Srt
  • Trasylol (Initial (test) Dose Of 1 Ml)
Subdural Haematoma, Dyspnoea, Unresponsive To Stimuli, Asthenia, Hyponatraemia, Renal Impairment

This is a Spironolactone side effect report of a female patient (weight:NA) from UNITED KINGDOM, suffering from the following symptoms/conditions: NA, who was treated with Spironolactone (dosage:NA, start time: Oct 28, 2010), combined with:
  • Gleevec (Unk)
  • Iloprost
  • Furosemide
  • Diuretics
, and developed a serious reaction and a Renal Impairment side effect. The patient presented with:
  • Subdural Haematoma
  • Dyspnoea
  • Unresponsive To Stimuli
  • Asthenia
  • Hyponatraemia
  • Renal Impairment
which developed after the beginning of treatment. The patient was hospitalized. This side effect report can indicate a possible existence of increased vulnerability to Spironolactone treatment in female patients suffering from NA, resulting in Renal Impairment.
Presyncope, Contraindication To Medical Treatment, Pallor, Blood Pressure Decreased, Renal Impairment, Ventricular Tachycardia, Electrocardiogram Qt Prolonged

A 77-year-old patient (weight: NA) from UNITED STATES with the following symptoms: NA started Spironolactone treatment (dosage: NA) on NS. Soon after starting Spironolactone treatment, the consumer experienced several side effects, including:
  • Presyncope
  • Contraindication To Medical Treatment
  • Pallor
  • Blood Pressure Decreased
  • Renal Impairment
  • Ventricular Tachycardia
  • Electrocardiogram Qt Prolonged
. Concurrently used drugs:
  • Daily Asa
  • Synthroid
  • Quinine Sulfate (2 Tablets, Twice)
  • Naproxen (aleve) (2 Tablets)
  • Lasix
This finding indicates that some patients can be more vulnerable to developing Spironolactone side effects, such as Renal Impairment.
Stress, Unevaluable Event, Pain, Anhedonia, Multi-organ Failure, Renal Impairment, Anxiety, Renal Injury, Mental Disorder

A patient from UNITED STATES was prescribed and started Spironolactone on Nov 22, 2009. After Spironolactone was administered, patient encountered several Spironolactone side effects: stress, unevaluable event, pain, anhedonia, multi-organ failure, renal impairment, anxiety, renal injury, mental disorder Additional patient health information: male , 76 years of age, weighting 180.8 lb, The consumer reported the following symptoms: . Spironolactone dosage: Unk. Concurrently used drugs:
  • Trasylol (200 Ml X 2, Unk)
  • Trasylol
  • Synthroid
  • Norvasc
International Normalised Ratio Increased, Mobility Decreased, Pain In Extremity, Asthenia, Rhabdomyolysis, Renal Impairment

This report suggests a potential Spironolactone Renal Impairment side effect(s) that can have serious consequences. A 69-year-old female patient from UNITED KINGDOM (weight:NA) was diagnosed with the following health condition(s): NA and used Spironolactone (dosage: 25 Mg, Daily) starting Oct 01, 2009. Soon after starting Spironolactone the patient began experiencing various side effects, including:
  • International Normalised Ratio Increased
  • Mobility Decreased
  • Pain In Extremity
  • Asthenia
  • Rhabdomyolysis
  • Renal Impairment
Drugs used concurrently:
  • Aspirin (75 Mg, Daily)
  • Citalopram (20 Mg, Daily)
  • Codeine Sulfate (60 Mg, Prn)
  • Frusemide /00032601/ (Unk)
  • Simvastatin (40 Mg, Daily)
  • Warfarin Sodium (Unk)
  • Balsalazide Disodium (750 Mg, Tid)
  • Bumetanide (1 Mg, Bid)
The patient was hospitalized and became disabled. Although Spironolactone demonstrated significant improvements in a number of clinically relevant cases, troublesome symptoms, such as Renal Impairment, may still occur.
Altered State Of Consciousness, Hypoglycaemia, Renal Impairment

An adverse event was reported by a physician on Nov 18, 2009 by a Female taking Spironolactone (dosage: 25 Mg,daily) . Location: JAPAN , 83 years of age, weighting 101.4 lb, patient began experiencing various side effects, including: Patient felt the following Spironolactone side effects: altered state of consciousness, hypoglycaemia, renal impairment. Additional medications/treatments:
Multiple prescriptions taken:
  • Cibenzoline Succinate (200 Mg, Daily)
  • Furosemide (40 Mg, Daily)
  • Famotidine (20 Mg, Unk)
  • Metildigoxin (0.5 Mg, Unk)
  • Allopurinol (100 Mg, Unk)
  • Rebamipide (300 Mg, Unk)
  • Warfarin Sodium (2 Mg, Unk)
The patient was hospitalized.
Altered State Of Consciousness, Hypoglycaemia, Renal Impairment

This Renal Impairment problem was reported by a physician from JAPAN. A 83-year-old female patient (weight: NA) was diagnosed with the following medical condition(s): NA.On Feb 12, 2008 a consumer started treatment with Spironolactone (dosage: 25 Mg,daily). The following drugs/medications were being taken at the same time:
  • Cibenzoline Succinate (200 Mg, Daily)
  • Furosemide (40 Mg, Daily)
  • Famotidine (20 Mg, Unk)
  • Metildigoxin (0.5 Mg, Unk)
  • Allopurinol (100 Mg, Unk)
  • Rebamipide (300 Mg, Unk)
  • Warfarin Sodium (2 Mg, Unk)
When commencing Spironolactone, the patient experienced the following unwanted symptoms /side effects:
  • Altered State Of Consciousness
  • Hypoglycaemia
  • Renal Impairment
The patient was hospitalized. Although all drugs are carefully tested before they are licensed for use, they carry potential side effect risks. Some side effects, such as Renal Impairment, may become evident only after a product is in use by the general population.
Renal Impairment

This is a Spironolactone side effect report of a female patient (weight: NA) from UNITED STATES. The patient developed the following symptoms/conditions: NA and was treated with Spironolactone (dosage: 25mg Tablet 25 Mg Qd Oral) starting Apr 02, 2009. Concurrently used drugs:
  • Aspirin
  • Atenolol
  • Epi Pen (epinephrine Autoinjector)
  • Hydrochlorothiazide
  • Klonopin
  • Lipitor
  • Lisinopril
  • Loprox Gel
Soon after that, the consumer experienced the following of symptoms:
  • Renal Impairment
This opens a possibility that Spironolactone could cause Renal Impairment and that some female patients may be more susceptible.
Hyperkalaemia, Renal Impairment

This Renal Impairment side effect was reported by a pharmacist from UNITED STATES on Feb 23, 2009. A patient from UNITED STATES , 76 years of age, weighting 154.3 lb, was diagnosed with and was treated with Spironolactone. Patient felt the following Spironolactone side effects: hyperkalaemia, renal impairment. Spironolactone dosage: 100 Mg Every Day Po. The patient was hospitalized. These side effects may potentially be related to Spironolactone.

DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

Spironolactone Renal Impairment Causes and Reviews


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Spironolactone Renal Impairment Reviews

Tue, 09 Nov 2010

I am a female patient from NY, age 33. I am being treated for Hashimoto Thyroiditis with Synthroid and Cytomel. I was concerned that after 11 years since my diagnosis, my hair is still falling out at an alarming rate. My doctor noticed that my testosterone levels were a bit high and decided to treat me with Spironolactone (50 MG). I noticed no difference in the amount of hair loss but have been having constant, uncomfortable eye spasms and a breast tenderness as well as breast enlargement. This is just after a little over a month of treatment. I will stop taking Spironolactone as I do not see it as being beneficial to me.

Wed, 02 May 2012

I'm a 29 year old female and started taking spiro to get rid of my persistent adult acne. I took 100mg a day for about 2 weeks and it worked really quickly to clear my skin, I also went up an entire cup size which was a bonus and because it stopped any fluid retention I lost a bit of weight as well.
Unfortunately I had to stop taking it because of the side effects. The worst was a really low mood and anxiety, I would take it and half an hour later have to skull 2-3 litres of water, wee it all out and then couldn't sleep because my heart was racing to much and I felt really on edge. I also felt slightly nauseous all of the time (probably contributed to the weight loss) and found that it made me fart a lot. 
I'm going to try it again though, this time on a lower dosage just a few times a week to see how that goes.

Thu, 18 Aug 2011

mid morningstablets of 25 mg working very well at reducing excess water -edema-but have bouts of diarrhorea

Sat, 16 Jan 2010
I was on Spironolactone (12.5 daily) . Hindsight, almost immediately I began suffering from ED. Mixed symptoms thought at the time from Diabetes T2 . Was also on Ace Inhibitors, Digoxin, Ibuprofenm Furosemide. After 18 months suddenly developed MAJOR heartburn and EXTREMELY sore nipples. When GP was told of new symptons, was immediately told to halt Spiron. I have been off of it for 4 months now, but STILL experience nipple pain. Can anyone tell me how to stop the pain ?? I was told that it would go away, but I am starting to wonder. I am a 58 yo WM, 5'7, 250# . My chest has increased 2 'cup' sizes at least. Would like to find out how to reverse these unwanted effects.
Thu, 03 Feb 2011
Painful intercorse
Wed, 18 May 2011
I'm 27 f female from aust, i have been taking Spironolactone for about four months now. I have been prescribed this due to hair loss (thining really quickly) and i have found it to be amazing! I have been having mood swings as a result and headaches... however apart from that I couldnt be happier. My hair has stopped falling out! the hair i have is so much thicker and healthier... i dont wear a hat anymore and i got a knot in my hair for the first time yesterday.. sounds strange, but i was over the moon about it :) being able to grow my hair again has made me so happy I have had to take regular blood test to keep an eye on my levels. So far so good :)
DISCLAIMER: ALL DATA PROVIDED AS-IS, refer to terms of use for additional information.

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Top Spironolactone Side Effects

Hyperkalaemia (208)
Renal Failure Acute (103)
Dyspnoea (81)
Dehydration (59)
Asthenia (56)
Gynaecomastia (55)
Diarrhoea (52)
Nausea (50)
Blood Potassium Increased (50)
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Fatigue (46)
Hypotension (43)
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Dizziness (40)
Pain (37)
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Renal Impairment (28)
Condition Aggravated (27)
Malaise (26)
Chest Pain (25)
Cardiac Failure (25)
Cough (25)
Fall (25)
Anaemia (24)
Pyrexia (23)
Pruritus (23)
Back Pain (22)
Rash (22)
Death (21)
Hypertension (21)
Blood Urea Increased (20)
Anxiety (20)
Blood Pressure Decreased (20)
Cardiac Failure Congestive (20)
Headache (20)
Weight Increased (19)
Pulmonary Embolism (18)
Blood Pressure Increased (18)
Breast Pain (18)
Confusional State (17)
Weight Decreased (17)
Hypokalaemia (17)
Syncope (16)
Pneumonia (16)
Myocardial Infarction (16)
Oedema (15)

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