Diarrhea Predominant Irritable Bowel Syndrome | The Effects of Soy Dietary Fiber in Adults With Diarrhea Predominant Irritable Bowel Syndrome
Diarrhea Predominant Irritable Bowel Syndrome research study
What is the primary objective of this study?
The investigators will evaluate the efficacy of soy dietary fiber in adults with diarrhea predominant irritable bowel syndrome.
Who is eligible to participate?
Inclusion Criteria: - willing to consent/undergo necessary procedures - between the age of 19 and 75 years - diarrhea predominant irritable bowel syndrome (satisfied with Rome II criteria) Exclusion Criteria: - uncontrolled hypertension (Blood pressure > 170/100 mmHg) - uncontrolled diabetes mellitus (FBS > 180 mg/dL) - malignancy, cerebrovascular disease, cardiovascular disease - history of abdominal surgery except appendectomy and hernia repair - inflammatory bowel disease - clinically or laboratory-confirmed gastroenteritis - the use of motility drug or dietary fiber supplement in 2 weeks - allergy to soy fiber - serum Cr > 2 x Upper normal limit - AST or ALT > 2 x Upper normal limit - Pregnancy, Lactating woman
Which medical condition, disease, disorder, syndrome, illness, or injury is researched?
Diarrhea Predominant Irritable Bowel Syndrome
Interventions can include giving participants drugs, medical devices, procedures, vaccines, and other products that are either investigational or already available or noninvasive approaches such as surveys, education, and interviews.
Dietary Supplement:Soy Dietary FiberSoy Dietary Fiber, Once a day, before meal, 1 pack(20g), per oral with water 90mL
Dietary Supplement:Rice powderRice powder, Once a day, before meal, 1 pack(20g), per oral with water 90mL
Research studies and clinical trials typically have two or more research arms. An arm is a group of people who receive the same treatment in the study.
Soy Dietary Fiber
Start Date: July 2011
Completed Date: July 2012
Primary Outcome: sum of irritable bowel syndrome symptom score
Secondary Outcome: irritable bowel syndrome symptom score
Study sponsors, principal investigator, and references
Principal Investigator: Joo Sung Kim, M.D., PhD
Lead Sponsor: Seoul National University Hospital